Der Deutsche Germanistenverband –: eine „Fachgenossenschaft“ im Zielkonflikt

Deutscher Germanistenverband: An Academic Association in a Conflict of Objectives From its inauguration in 1912 until 1933 the DGV resembled an ideological society successfully pursuing anti-modern nationalistic goals in the area of educational and school policy with modern methods. At best, it might be said to have only marginally fulfilled the role of an academic association for the field of study. While it did not actively seek to join the National Socialist movement, it did not resist it either. Only since its annually held conference in966 has the DGV started to deal with its past and subsequently reformed the association’s activities rigorously to become a modern academic association. What remains problematic today, is the fact that the DGV represents both the interests of German scholars from higher education and those of school teachers of German – which in fact frequently diverge from each other – and therefore, due to internal differentiation, is in danger of being reduced to being an umbrella association

Stadt - Mann - Universität. Hamburg, Werner von Melle und ein Jahrhundert-Lebenswerk: Teil 1. Der Mann und die Stadt

How to become a Hanseatic? What made someone a (Hamburg) Patriot? Why was it not possible for a high-shool graduate to study in Hamburg before 1918? How was it possible that catastrophes in the 19th century led to modernisation in Hamburg? This publications will answer to questions like these.Around 1850 Hamburg underwent radical changes. Werner von Melle, born in 1853, played an active and forming part in the history of the city as a solicitor, senator, and mayor. Being the first president of the Hamburgische Wissenschaftliche Stiftung, he devoted himself to the foundation of the University of Hamburg.This first part of his biography deals with the complex relations between the man and the city

August Sauer (1855-1926)

Der Prager Germanist August Sauer wirkte nicht nur im engeren akademischen Rahmen an der dortigen Karl-Ferdinand-Universität, sondern auch in kultur- und wissenschaftspolitischer Hinsicht. Sein Einfluss auf die intellektuellen und wissenschaftlichen Diskurse in Böhmen bzw. später der Tschechoslowakei, aber auch auf Habsburg-Österreich insgesamt ist von nicht zu unterschätzender Bedeutung. Der vorliegende Sammelband würdigt August Sauers Werk aus literatur-, kultur- und geschichtswissenschaftlicher Perspektive, bei der der kultur- und wissenschaftspolitische Kontext genauso in den Blick genommen wird wie der engere fachhistorische Rahmen

Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe: A prospective European multicentre observational study

BACKGROUND: Little is known about current clinical practice concerning peri-operative red blood cell transfusion in neonates and small infants. Guidelines suggest transfusions based on haemoglobin thresholds ranging from 8.5 to 12 g dl-1, distinguishing between children from birth to day 7 (week 1), from day 8 to day 14 (week 2) or from day 15 (≥week 3) onwards. OBJECTIVE: To observe peri-operative red blood cell transfusion practice according to guidelines in relation to patient outcome. DESIGN: A multicentre observational study. SETTING: The NEonate-Children sTudy of Anaesthesia pRactice IN Europe (NECTARINE) trial recruited patients up to 60 weeks' postmenstrual age undergoing anaesthesia for surgical or diagnostic procedures from 165 centres in 31 European countries between March 2016 and January 2017. PATIENTS: The data included 5609 patients undergoing 6542 procedures. Inclusion criteria was a peri-operative red blood cell transfusion. MAIN OUTCOME MEASURES: The primary endpoint was the haemoglobin level triggering a transfusion for neonates in week 1, week 2 and week 3. Secondary endpoints were transfusion volumes, 'delta haemoglobin' (preprocedure - transfusion-triggering) and 30-day and 90-day morbidity and mortality. RESULTS: Peri-operative red blood cell transfusions were recorded during 447 procedures (6.9%). The median haemoglobin levels triggering a transfusion were 9.6 [IQR 8.7 to 10.9] g dl-1 for neonates in week 1, 9.6 [7.7 to 10.4] g dl-1 in week 2 and 8.0 [7.3 to 9.0] g dl-1 in week 3. The median transfusion volume was 17.1 [11.1 to 26.4] ml kg-1 with a median delta haemoglobin of 1.8 [0.0 to 3.6] g dl-1. Thirty-day morbidity was 47.8% with an overall mortality of 11.3%. CONCLUSIONS: Results indicate lower transfusion-triggering haemoglobin thresholds in clinical practice than suggested by current guidelines. The high morbidity and mortality of this NECTARINE sub-cohort calls for investigative action and evidence-based guidelines addressing peri-operative red blood cell transfusions strategies. TRIAL REGISTRATION: ClinicalTrials.gov, identifier: NCT02350348

The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age  6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score  652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)

From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions

Stadt – Mann – Universität. Hamburg, Werner von Melle und ein Jahrhundert-Lebenswerk: Teil 1 (Der Mann und die Stadt)

Wie wird man zum Hanseaten und was ist ein (Hamburger) Patriot? Warum konnte ein Abiturient bis 1918 nicht in Hamburg studieren und wieso führten Katastrophen im 19. Jahrhundert zu Modernisierungsschüben in der Freien und Hansestadt? Fragen dieser Art durchziehen das Buch – die meisten werden beantwortet. Um 1850 neigt sich ein gediegenes Großkapitel Hamburger Stadtgeschichte dem Ende zu. Am Beginn des neuen steht die Geburt eines Knaben. Werner von Melles Durchsetzungswillen verdankt Hamburg nicht zuletzt die Universität. Die Biographie über den ersten Präsidenten der Hamburgischen Wissenschaftlichen Stiftung erzählt die Geschichte seines langen Lebensweges im Koordinatennetz politischer Systeme und hanseatischer Stadtkultur. Ihr erster Teil ist Zeugnis einer komplexen Liebe und Partnerschaft zwischen dem Mann und der Stadt.How to become a Hanseatic? What made someone a (Hamburg) Patriot? Why was it not possible for a high-shool graduate to study in Hamburg before 1918? How was it possible that catastrophes in the 19th century led to modernisation in Hamburg? This publications will answer to questions like these. Around 1850 Hamburg underwent radical changes. Werner von Melle, born in 1853, played an active and forming part in the history of the city as a solicitor, senator, and mayor. Being the first president of the Hamburgische Wissenschaftliche Stiftung, he devoted himself to the foundation of the University of Hamburg. This first part of his biography deals with the complex relations between the man and the city

Stadt - Mann - Universität. Hamburg, Werner von Melle und ein Jahrhundert-Lebenswerk: Teil 1. Der Mann und die Stadt

How to become a Hanseatic? What made someone a (Hamburg) Patriot? Why was it not possible for a high-shool graduate to study in Hamburg before 1918? How was it possible that catastrophes in the 19th century led to modernisation in Hamburg? This publications will answer to questions like these.Around 1850 Hamburg underwent radical changes. Werner von Melle, born in 1853, played an active and forming part in the history of the city as a solicitor, senator, and mayor. Being the first president of the Hamburgische Wissenschaftliche Stiftung, he devoted himself to the foundation of the University of Hamburg.This first part of his biography deals with the complex relations between the man and the city

Special Issue on Ambient Assisted Living

International audienc