Characterization of Leishmania spp. causing cutaneous leishmaniasis in Manaus, Amazonas, Brazil

In the State of Amazonas, American tegumentary leishmaniasis is endemic and presents a wide spectrum of clinical variability due to the large diversity of circulating species in the region. Isolates from patients in Manaus and its metropolitan region were characterized using monoclonal antibodies and isoenzymes belonging to four species of the parasite: Leishmania (Viannia) guyanensis, 73% (153/209); Leishmania (Viannia) braziliensis, 14% (30/209); Leishmania (Leishmania) amazonensis, 8% (17/209); and Leishmania (Viannia) naiffii, 4% (9/209). The most prevalent species was L. (V.) guyanensis. The principal finding of this study was the important quantity of infections involving more than one parasite species, representing 14% (29/209) of the total. The findings obtained in this work regarding the parasite are further highlighted by the fact that these isolates were obtained from clinical samples collected from single lesions

The southern Araçuaí belt and the Dom Silvério Group: geologic architecture and tectonic significance

The Araçuaí belt corresponds to the external portion of the western half of the Araçuaí-West Congo Neopro-terozoic orogen. TheAraçuaí belt fringes the São Francisco craton to east and is separated from the crystalline core of the orogen by the Abre Campo geophysical discontinuity. The southern Araçuaí belt involves four major lithologic units: the Archean and Paleoproterozoic gneisses of the Mantiqueira Complex, the Pedra Dourada Charnockite, the Paleoproterozoic Borrachudos Granitoid, and the metavolcanosedimentary rocks of the Dom Silvério Group. The Dom Silvério Group occurs in a NNE-SSW striking belt and consists of a thick package of metapelitic rocks with intercalations of quartzites, amphibolites, meta-ultramafics, banded iron formations, gondites and marbles. All units of the southern Araçuaí belt underwent four syn-metamorphic phases of deformation in the course of the Brasiliano event. The first phase, synchronous to a regional amphibolite facies metamorphism, was associated to a general tectonic transport towards north along the left-lateral Dom Silvério shear zone and its low angle segment. The second and third phases represent progressive stages of a west directed shortening, which led to the development of local thrusts and pervasive folds in several scales. The fourth phase is extensional and reflects the collapse of the orogen.<br>A Faixa Araçuaí corresponde à porção ocidental externa do orógeno neoproterozóico Araçuaí-Congo Ocidental. Margeia a borda leste do Cráton do São Francisco e é separada do núcleo cristalino do orógeno pela descontinuidade geofísica de Abre Campo. A porção meridional da Faixa Araçuaí envolve quatro unidades litológicas principais: os ortognaisses arqueanos e paleoproterozóicos do Complexo Mantiqueira, os charnoquitos Pedra Dourada, os granitóides paleoproterozóicos da Suíte Borrachudos e as rochas metavulcanossedimentares do Grupo Dom Silvério. O Grupo Dom Silvério ocorre em uma faixa NNE-SSW e engloba um pacote de rochas metapelíticas com intercalações de quartzitos, anfibolitos, meta-ultramáficas, formações ferríferas, gonditos e mármores. Todas as unidades da porção meridional da Faixa Araçuaí foram envolvidas em quatro fases deformacionais sin-metamórficas no curso do Evento Brasiliano. A primeira fase, sincrônica a um metamorfismo regional de fácies anfibolito, associou-se a um transporte tectônico geral para norte ao longo da zona de cisalhamento sinistral de Dom Silvério e no segmento de baixo ângulo a ela conectado. A segunda e terceira fases representam estágios progressivos de um encurtamento com movimentação geral para oeste, com desenvolvimento de empurrões localizados e intenso dobramento em todas as escalas. A quarta fase é extensional e reflete o colapso do orógeno