Fermionic Casimir effect with helix boundary condition

In this paper, we consider the fermionic Casimir effect under a new type of space-time topology using the concept of quotient topology. The relation between the new topology and that in Ref. \cite{Feng,Zhai3} is something like that between a M\"obius strip and a cylindric. We obtain the exact results of the Casimir energy and force for the massless and massive Dirac fields in the ($D+1$)-dimensional space-time. For both massless and massive cases, there is a $Z_2$ symmetry for the Casimir energy. To see the effect of the mass, we compare the result with that of the massless one and we found that the Casimir force approaches the result of the force in the massless case when the mass tends to zero and vanishes when the mass tends to infinity.Comment: 7 pages, 4 figures, published in Eur. Phys. J.

An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone

Most known thioredoxin-type proteins (Trx) participate in redox pathways, using two highly conserved cysteine residues to catalyze thiol-disulfide exchange reactions. Here we demonstrate that the so far unexplored Trx2 from African trypanosomes (Trypanosoma brucei) lacks protein disulfide reductase activity but functions as an effective temperature-activated and redox-regulated chaperone. Immunofluorescence microscopy and fractionated cell lysis revealed that Trx2 is located in the mitochondrion of the parasite. RNA-interference and gene knock-out approaches showed that depletion of Trx2 impairs growth of both mammalian bloodstream and insect stage procyclic parasites. Procyclic cells lacking Trx2 stop proliferation under standard culture conditions at 27°C and are unable to survive prolonged exposure to 37°C, indicating that Trx2 plays a vital role that becomes augmented under heat stress. Moreover, we found that Trx2 contributes to the in vivo infectivity of T. brucei. Remarkably, a Trx2 version, in which all five cysteines were replaced by serine residues, complements for the wildtype protein in conditional knock-out cells and confers parasite infectivity in the mouse model. Characterization of the recombinant protein revealed that Trx2 can coordinate an iron sulfur cluster and is highly sensitive towards spontaneous oxidation. Moreover, we discovered that both wildtype and mutant Trx2 protect other proteins against thermal aggregation and preserve their ability to refold upon return to non-stress conditions. Activation of the chaperone function of Trx2 appears to be triggered by temperature-mediated structural changes and inhibited by oxidative disulfide bond formation. Our studies indicate that Trx2 acts as a novel chaperone in the unique single mitochondrion of T. brucei and reveal a new perspective regarding the physiological function of thioredoxin-type proteins in trypanosomes

Correlation analysis of field-aligned currents measured by Swarm

The orientation of field-aligned current sheets (FACs) can be inferred from dual-spacecraft correlations of the FAC signatures between two Swarm spacecraft (A and C), using the maximum correlations obtained from sliding data segments. Statistical analysis of both the correlations and the inferred orientations shows clear trends in magnetic local time (MLT) which reveal behaviour of both large and small scale currents. The maximum correlation coefficients show distinct behaviour in terms of either the time shift, or the shift in longitude between Swarm A and C for various filtering levels. The low-latitude FACs show the strongest correlations for a broad range of MLT centred on dawn and dusk, with a higher correlation coefficient on the dusk-side and lower correlations near noon and midnight. The current sheet orientations are shown to broadly follow the mean shape of the auroral boundary for the lower latitudes corresponding to Region 2 FACs and that these are most well-ordered on the dusk side. Together with these correlation trends, individual events have also been sampled by higher altitude spacecraft in conjunction with Swarm (mapping both to region 1 and 2), showing that two different domains of FACs are apparent: small-scale (some tens of km) which are time variable and large-scale (>100 km) which are rather stationary. We investigate further how these FAC regimes are dependent on geomagnetic activity, focusing on high activity events. The trends found here for different activities are compared to effects seen in the ground magnetometer signals (dH/dt)

CP Violation in Tau Slepton Pair Production at Muon Colliders

We discuss in detail signals for CP violation in the Higgs boson and tau-slepton sectors through the production processes $\mu^+\mu^- \to \tilde{\tau}_i^- \tilde{\tau}_j^+$, where $i,j=1,2$ label the two $\tau$ slepton mass eigenstates in the minimal supersymmetric standard model. We assume that the soft breaking parameters of third generation sfermions contain CP violating phases, which induce CP violation in the Higgs sector through quantum corrections. We classify all the observables for probing CP violation in the Higgs boson and $\tau$ slepton sectors. These observables depend on the initial muon beam polarization, where we include transverse polarization states. If the heavy Higgs bosons can decay into tau slepton pairs, a complete determination of the CP properties of the neutral Higgs boson and $\tau$--slepton systems is possible. The interference between the Higgs boson and gauge boson contributions could also provide a powerful method for probing CP violation, if transversely polarized muon beams are available. We show in detail how to directly measure CP violation in the tau slepton system, under the assumption that the neutral Higgs mixing angles are determined through the on--shell production of the neutral Higgs bosons.Comment: 38 pages, 9 figures Including 7 eps ones. A figure to show the dependence on tan(beta) and the mass parameters of the sfermion sectors and a reference added. To appear in Phys. Rev.

Coherent electron-phonon coupling and polaron-like transport in molecular wires

We present a technique to calculate the transport properties through one-dimensional models of molecular wires. The calculations include inelastic electron scattering due to electron-lattice interaction. The coupling between the electron and the lattice is crucial to determine the transport properties in one-dimensional systems subject to Peierls transition since it drives the transition itself. The electron-phonon coupling is treated as a quantum coherent process, in the sense that no random dephasing due to electron-phonon interactions is introduced in the scattering wave functions. We show that charge carrier injection, even in the tunneling regime, induces lattice distortions localized around the tunneling electron. The transport in the molecular wire is due to polaron-like propagation. We show typical examples of the lattice distortions induced by charge injection into the wire. In the tunneling regime, the electron transmission is strongly enhanced in comparison with the case of elastic scattering through the undistorted molecular wire. We also show that although lattice fluctuations modify the electron transmission through the wire, the modifications are qualitatively different from those obtained by the quantum electron-phonon inelastic scattering technique. Our results should hold in principle for other one-dimensional atomic-scale wires subject to Peierls transitions.Comment: 21 pages, 8 figures, accepted for publication in Phys. Rev. B (to appear march 2001

Search for single top quarks in the tau+jets channel using 4.8 fb−1^{-1} of ppˉp\bar{p} collision data

We present the first direct search for single top quark production using tau leptons. The search is based on 4.8 fb$^{-1}$ of integrated luminosity collected in $p\bar{p}$ collisions at $\sqrt{s}$=1.96 TeV with the D0 detector at the Fermilab Tevatron Collider. We select events with a final state including an isolated tau lepton, missing transverse energy, two or three jets, one or two of them $b$ tagged. We use a multivariate technique to discriminate signal from background. The number of events observed in data in this final state is consistent with the signal plus background expectation. We set in the tau+jets channel an upper limit on the single top quark cross section of \TauLimObs pb at the 95% C.L. This measurement allows a gain of 4% in expected sensitivity for the observation of single top production when combining it with electron+jets and muon+jets channels already published by the D0 collaboration with 2.3 fb$^{-1}$ of data. We measure a combined cross section of \SuperCombineXSall pb, which is the most precise measurement to date.Comment: 12 pages, 5 figure

Physics searches at the LHC

With the LHC up and running, the focus of experimental and theoretical high energy physics will soon turn to an interpretation of LHC data in terms of the physics of electroweak symmetry breaking and the TeV scale. We present here a broad review of models for new TeV-scale physics and their LHC signatures. In addition, we discuss possible new physics signatures and describe how they can be linked to specific models of physics beyond the Standard Model. Finally, we illustrate how the LHC era could culminate in a detailed understanding of the underlying principles of TeV-scale physics.Comment: 184 pages, 55 figures, 14 tables, hundreds of references; scientific feedback is welcome and encouraged. v2: text, references and Overview Table added; feedback still welcom

Profiling of antioxidant potential and phytoconstituents of Plantago coronopus

The halophyte species Plantago coronopus has several described ethnomedicinal uses, but few reported biological activities. This work carried out for the first time a comparative analysis of P. coronopus organs in terms of phenolic composition and antioxidant activity of organic and water extracts from roots, leaves and flowers. The leaves contents in selected nutrients, namely amino acids and minerals, are also described. Roots (ethyl acetate and methanol extracts) had the highest radical scavenging activity (RSA) towards 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals, while leaves (hexane extract) had higher RSA on nitric oxide radical and iron chelating ability. High performance liquid chromatography (HPLC) analysis identified eighteen phenolics from which salicylic acid and epicatechin are here firstly described in Plantago species. Leaves had mineral levels similar to those of most vegetables, proving to be a good source for elements like calcium, sodium, iron and magnesium, and also for several of the essential amino acids justifying it use as food. Our results, especially those regarding the phenolics composition, can explain the main traditional uses given to this plantain and, altogether, emphasize the potential of P. coronopus as a source of bioactive molecules particularly useful for the prevention of oxidative stress-related diseases

Taxonomy based on science is necessary for global conservation

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