195 research outputs found

    The Havana Capitol, geometry and proportion through its original plans

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    [EN] The research on the National Capitol Building in Havana, Cuba, aims to study the building and its constructive solutions and materials, by means of the extensive graphic and photographic documentation preserved in the archives of the city. This documentation is a rigorous source of technical information, useful for analyzing the building in detail and understanding and dating its different construction phases. The research was developed in the city of Havana, Cuba, in the last five years in coordination with the Office of the City Historian, and it allowed creating a significant collection of plans, images and other graphic documents as a basis for future research. This article focuses on analyzing the work from its original plans (geometry and proportion, techniques of representation and graphic quality), which are a work of art by themselves, a meticulous handwork done by several Cuban architects and engineers. These documents have never seen the light until now.[ES] El objetivo de la investigación realizada en el Capitolio de La Habana se centra en estudiar el edificio, sus soluciones constructivas y materiales, en base a la extensa documentación gráfica y fotográfica existente en los diferentes archivos de la ciudad. Esta documentación constituye una fuente rigurosa de información técnica, útil para analizar en detalle el edificio y comprender y datar sus diferentes fases constructivas. La investigación ha sido desarrollada en La Habana, Cuba, durante los últimos cinco años en coordinación con la Oficina del Historiador de la Ciudad y ha permitido crear un archivo de planos, imágenes, y otros documentos gráficos como base de futuras investigaciones. Este artículo se centra en analizar la obra a partir de sus planos originales (geometría y proporción, técnicas de representación, calidad gráfica), que son una obra de arte en sí mismos y que nunca hasta ahora han visto la luz. Se trata de un minucioso trabajo realizado a mano por varios arquitectos e ingenieros cubanos.Mestre Martí, M.; Jiménez Delgado, A.; Ródenas López, M.; Jiménez Vicario, PM. (2018). El Capitolio de La Habana, geometría y proporción a través de sus planos originales. EGA. Revista de Expresión Gráfica Arquitectónica. 23(33):40-51. doi:10.4995/ega.2018.8859SWORD40512333DE LAS CUEVAS TORAYA, J. , (2001) . 500 years of construction in Cuba . Havana: Chavin. Servicios Gráficos y Editoriales, SLTHE ARCHITECT, (1933). No. 38. "The Capitol seen by an Architect ". The Architect, no. 38, p. 352FERNÁNDEZ, P. y Cía , (1933). The Book of the Capitol . Havana.SECRETARIAT OF PUBLIC WORKS (1931) . Inventory of non-consumable property of the Capitol. Havana: Ministry of Public Works.VEGA BOLAÑO, E., (2010). Diagnostic study of the cover of the National Capitol . Project of unpublished degree. Directors: MSc. Ing. Frank Díaz Alemán; Dr. Eng. OdalysÁlvarez Rodríguez. Havana: José Antonio Echevarría Polytechnic Higher Institute. School of Civil Engineering

    Educational data mining for tutoring support in Higher Education: a web-based tool case study in engineering degrees

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    This paper presents a web-based software tool for tutoring support of engineering students without any need of data scientist background for usage. This tool is focused on the analysis of students' performance, in terms of the observable scores and of the completion of their studies. For that purpose, it uses a data set that only contains features typically gathered by university administrations about the students, degrees and subjects. The web-based tool provides access to results from different analyses. Clustering and visualization in a low-dimensional representation of students' data help an analyst to discover patterns. The coordinated visualization of aggregated students' performance into histograms, which are automatically updated subject to custom filters set interactively by an analyst, can be used to facilitate the validation of hypotheses about a set of students. Classification of students already graduated over three performance levels using exploratory variables and early performance information is used to understand the degree of course-dependency of students' behavior at different degrees. The analysis of the impact of the student's explanatory variables and early performance in the graduation probability can lead to a better understanding of the causes of dropout. Preliminary experiments on data of the engineering students from the 6 institutions associated to this project were used to define the final implementation of the web-based tool. Preliminary results for classification and drop-out were acceptable since accuracies were higher than 90% in some cases. The usefulness of the tool is discussed with respect to the stated goals, showing its potential for the support of early profiling of students. Real data from engineering degrees of EU Higher Education institutions show the potential of the tool for managing high education and validate its applicability on real scenarios.This work was supported by the Erasmus+ Key Action 2 Strategic Partnerships KA203, funded by the European Commission, under Grant 2016-1-ES01-KA203-025452.info:eu-repo/semantics/publishedVersio

    Data mining tool for academic data exploitation: literature review and first architecture proposal

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    Using data for making decisions is not new; companies use complex computations on customer data for business intelligence or analytics. Business intelligence techniques can discern historical patterns and trends from data and can create models that predict future trends and patterns. Analytics, broadly defined, comprises applied techniques from computer science, mathematics, and statistics for extracting usable information from very large datasets. Data itself is not new. Data has always been generated and used to inform decision-making. However, most of this was structured and organised, through regular data collections, surveys, etc. What is new, with the invention and dominance of the Internet and the expansion of digital systems across all sectors, is the amount of unstructured data we are generating. This is what we call the digital footprint: the traces that individuals leave behind as they interact with their increasingly digital world. Data analytics is the process where data is collected and analysed in order to identify patterns, make predictions, and inform business decisions. Our capacity to perform increasingly sophisticated analytics is changing the way we make predictions and decisions, with huge potential to improve competitive intelligence. These examples suggest that the actions from data mining and analytics are always automatic, but that is less often the case. Educational Data Mining (EDM) and Learning Analytics (LA) have the potential to make visible data that have heretofore gone unseen, unnoticed, and therefore unactionable. To help further the fields and gain value from their practical applications, the recommendations are that educators and administrators: • Develop a culture of using data for making instructional decisions; • Involve IT departments in planning for data collection and use; • Be smart data consumers who ask critical questions about commercial offerings and create demand for the most useful features and uses; • Start with focused areas where data will help, show success, and then expand to new areas; • Communicate with students and parents about where data come from and how the data are used; • Help align state policies with technical requirements for online learning systems. This report documents the first steps conducted within the SPEET1 ERASMUS+ project. It describes the conceptualization of a practical tool for the application of EDM/LA techniques to currently available academic data. The document is also intended to contextualise the use of Big Data within the academic sector, with special emphasis on the role that student profiles and student clustering do have in support tutoring actions. The report describes the promise of educational data mining (seeking patterns in data across many student actions), learning analytics (applying predictive models that provide actionable information), and visual data analytics (interactive displays of analyzed data) and how they might serve the future of personalized learning and the development and continuous improvement of adaptive systems. How might they operate in an adaptive learning system? What inputs and outputs are to be expected? In the next sections, these questions are addressed by giving a system-level view of how data mining and analytics could improve teaching and learning by creating feedback loops. Finally, the proposal of the key elements that conform a software application that is intended to give support to this academic data analysis is presented. Three different key elements are presented: data, algorithms and application architecture. From one side we should have a minimum data available. The corresponding relational data base structure is presented. This basic data can always be complemented with other available data that may help to decide or/and to explain decisions. Classification algorithms are reviewed and is presented how they can be used for the generation of the student clustering problem. A convenient software architecture will act as an umbrella that connects the previous two parts. The document is intended to be useful for a first understanding of academic data analysis. What we can get and what we do need to do. This is the first of a series of reports that taken all together will provide a complete and consistent view towards the inclusion of data mining as a helping hand in the tutoring action.European UnionProgramme: Erasmus+ Project Reference: 2016-1-ES01-KA203-025452info:eu-repo/semantics/draf

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

    Organocatalytic asymmetric domino Michael–Henry reaction for the synthesis of substituted bicyclo[3.2.1]octan-2-ones

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    This paper was submitted for publication in the journal "Chemical Communications" and the definitive version can be found at: http://dx.doi.org/10.1039/c3cc39165eThe first organocatalytic asymmetric reaction between 1,4-cyclohexanedione and nitroalkenes have been studied, affording bicyclo[3.2.1]octane derivatives containing four continuous stereogenic centres. The products were obtained through a domino Michael-Henry process as a single diastereoisomer with excellent enantioselectivities

    Role of bioactive lipid mediators in obese adipose tissue inflammation and endocrine dysfunction

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    Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

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    Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p&lt;0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p&lt;0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised

    Global economic burden of unmet surgical need for appendicitis

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    Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and92 492 million using approach 1 and 73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and95 004 million using approach 1 and 75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
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