216 research outputs found
The Global Alliance for Infections in Surgery : defining a model for antimicrobial stewardship-results from an international cross-sectional survey
- Author
- Abbo Lilian M.
- Abu-Zidan FikriM.
- Adesunkanmi Abdulrashid K.
- Al-Dahir Sara
- Al-Hasan Majdi N.
- Alis Halil
- Alves Carlos
- Ansaloni Luca
- Araujo da Silva Andre R.
- Augustin Goran
- Bala Miklosh
- Barbadoro Pamela
- Barie Philip S.
- Beltran Marcelo A.
- Bhangu Aneel
- Bouchra Belefquih
- Brecher Stephen M.
- Brink Adrian J.
- Cainzos Miguel A.
- Camacho-Ortiz Adrian
- Carlet Jean
- Catani Marco
- Catena Fausto
- Chandy Sujith J.
- Cherry-Bukowiec Jill R.
- Chiara Osvaldo
- Chichom-Mefire Alain
- Coccolini Federico
- Colak Elif
- Cornely Oliver A.
- Cui Yunfeng
- De Simone Belinda
- de Souza Hamilton P.
- De Waele Jan J.
- Demetrashvili Zaza
- Dhingra Sameer
- Di Marzo Francesco
- Di Saverio Salomone
- Dogjani Agron
- Dorj Gereltuya
- Dortet Laurent
- Duane ThereseM.
- Elmangory Mutasim M.
- Enani Mushira A.
- Ferrada Paula
- Foianini J. Esteban
- Gachabayov Mahir
- Gandhi Chinmay
- Ghnnam Wagih Mommtaz
- Giamarellou Helen
- Gkiokas Georgios
- Gomi Harumi
- Goranovic Tatjana
- Griffiths Ewen A.
- Guerra Gronerth Rosio I.
- Haidamus Monteiro Julio C.
- Hardcastle Timothy C.
- Hecker Andreas
- Hodonou Adrien M.
- Ioannidis Orestis
- Isik Arda
- Iskandar Katia A.
- Jusoh Asri Che
- Kafil Hossein S.
- Kanj Souha S.
- Kaplan Lewis J.
- Kapoor Garima
- Karamarkovic Aleksandar R.
- Kenig Jakub
- Kerschaever Ivan
- Khamis Faryal
- Khanna Ashish
- Khokha Vladimir
- Kiguba Ronald
- Kim Hong B.
- Ko Wen-Chien
- Koike Kaoru
- Kozlovska Iryna
- Kumar Anand
- Labricciosa Francesco M.
- Lagunes Leonel
- Latifi Rifat
- Lee Jae G.
- Lee Young R.
- Leppaniemi Ari
- Li Yousheng
- Liang Stephen Y.
- Lowman Warren
- Machain Gustavo M.
- Maegele Marc
- Major Piotr
- Malama Sydney
- Manzano-Nunez Ramiro
- Marinis Athanasios
- Martinez Casas Isidro
- Marwah Sanjay
- Maseda Emilio
- May Addison K.
- McFarlane Michael E.
- Memish Ziad
- Mertz Dominik
- Mesina Cristian
- Mishra ShyamK.
- Moore Ernest E.
- Munyika Akutu
- Mylonakis Eleftherios
- Napolitano Lena
- Negoi Ionut
- Nestorovic Milica D.
- Nicolau David P.
- Omari Abdelkarim H.
- Ordonez Carlos A.
- Pagani Leonardo
- Paiva Jose-Artur
- Pant Narayan D.
- Parreira Jose G.
- Pedziwiatr Michal
- Pereira BrunoM.
- Pereira Nuno Rocha
- Ponce-de-Leon Alfredo
- Poulakou Garyphallia
- Preller Jacobus
- Pulcini Celine
- Pupelis Guntars
- Quiodettis Martha
- Rawson Timothy M.
- Reis Tarcisio
- Rems Miran
- Rizoli Sandro
- Roberts Jason
- Rodriguez-Bano Jesus
- Sakakushev Boris
- Sanders James
- Santos Natalia
- Sartelli Massimo
- Sato Norio
- Sawyer Robert G.
- Scarpelini Sandro
- Scoccia Loredana
- Scudeller Luigia
- Shafiq Nusrat
- Shelat Vishalkumar
- Sifri Costi D.
- Siribumrungwong Boonying
- Soreide Kjetil
- Soto Rodolfo
- Talving Peep
- Tessier Jeffrey M.
- Trung Ngo Tat
- Tumbarello Mario
- Ulrych Jan
- Uranues Selman
- Van Goor Harry
- Vereczkei Andras
- Viale Pierluigi
- Wagenlehner Floriann
- Watkins Richard R.
- Wechsler-Foerdoes Agnes
- Xiao Yonghong
- Yuan Kuo-Ching
- Zahar Jean-Ralph
- Zakrison Tanya L.
- Zuckerbraun Brian
- Zuidema Wietse P.
- Publication venue
- Publication date
- 01/01/2017
- Field of study
Background: Antimicrobial Stewardship Programs (ASPs) have been promoted to optimize antimicrobial usage and patient outcomes, and to reduce the emergence of antimicrobial-resistant organisms. However, the best strategies for an ASP are not definitively established and are likely to vary based on local culture, policy, and routine clinical practice, and probably limited resources in middle-income countries. The aim of this study is to evaluate structures and resources of antimicrobial stewardship teams (ASTs) in surgical departments from different regions of the world. Methods: A cross-sectional web-based survey was conducted in 2016 on 173 physicians who participated in the AGORA (Antimicrobials: A Global Alliance for Optimizing their Rational Use in Intra-Abdominal Infections) project and on 658 international experts in the fields of ASPs, infection control, and infections in surgery. Results: The response rate was 19.4%. One hundred fifty-six (98.7%) participants stated their hospital had a multidisciplinary AST. The median number of physicians working inside the team was five [interquartile range 4-6]. An infectious disease specialist, a microbiologist and an infection control specialist were, respectively, present in 80.1, 76.3, and 67.9% of the ASTs. A surgeon was a component in 59.0% of cases and was significantly more likely to be present in university hospitals (89.5%, p <0.05) compared to community teaching (83.3%) and community hospitals (66.7%). Protocols for pre-operative prophylaxis and for antimicrobial treatment of surgical infections were respectively implemented in 96.2 and 82.3% of the hospitals. The majority of the surgical departments implemented both persuasive and restrictive interventions (72.8%). The most common types of interventions in surgical departments were dissemination of educational materials (62.5%), expert approval (61.0%), audit and feedback (55.1%), educational outreach (53.7%), and compulsory order forms (51.5%). Conclusion: The survey showed a heterogeneous organization of ASPs worldwide, demonstrating the necessity of a multidisciplinary and collaborative approach in the battle against antimicrobial resistance in surgical infections, and the importance of educational efforts towards this goal.Peer reviewe
Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types
- Author
- Abdel-Rahman Mohamed H.
- Abeshouse Adam
- Adebamowo Clement
- Adebamowo Sally N.
- Agnew Kathy
- Ahn Keunsoo
- Ajani Jaffer A.
- Akbani Rehan
- Akeredolu Teniola
- Al-Ahmadie Hikmat
- Albert Monique
- Alexopoulou Iakovina
- Ally Adrian
- Alvaro Domenico
- Anderson Matthew L.
- Andry Chris
- Antenucci Anna
- Anur Pavana
- Appelbaum Elizabeth L.
- Aredes Natália D.
- Armenia Joshua
- Arnaout Angel
- Asa Sylvia L.
- Auman J. Todd
- Aymerich Marta
- Aziz Dina
- Bailey Matthew
- Balasundaram Miruna
- Balu Saianand
- Barnett Gene
- Barnholtz-Sloan Jill S.
- Barrett Wendi
- Bartlett John
- Bathe Oliver
- Baudin Eric
- Baylin Stephen
- Becker Karl-Friedrich
- Beer David
- Behera Madhusmita
- Behrens Carmen
- Bell Debra
- Bell Sue
- Bellair Michelle
- Bennett Joseph
- Benz Christopher
- Berchuck Andrew
- Berger Ashton C.
- Bergeron Alain
- Berkowitz Ross
- Bernard Brady
- Beroukhim Rameen
- Beuschlein Felix
- Bifulco Carlo
- Bigner Darell
- Birrer Michael
- Birsoy Kivanc
- Bocklage Therese
- Bodenheimer Tom
- Bondaruk Jolanta
- Bootwalla Moiz S.
- Borad Mitesh
- Borgia Jeffrey A.
- Bossler Aaron
- Botnariuc Natalia
- Boussioutas Alex
- Bowen Jay
- Bowlby Reanne
- Bowman Rayleen
- Bradford Carol
- Bragazzi Maria Consiglia
- Brat Daniel J.
- Breggia Anne
- Brewer Cathy
- Brimo Fadi
- Broaddus Russell
- Brooks Denise
- Broom Bradley M.
- Broudy Thomas
- Bryce Alan H.
- Bubley Glenn
- Bueno Raphael
- Burnette Andrew
- Caesar-Johnson Samantha J.
- Calatozzolo Chiara
- Campo Elias
- Campos Benito
- Caraman Irina
- Cardinale Vincenzo
- Carey Francis
- Carey Thomas
- Carlotti Carlos Gilberto
- Carlsen Rebecca
- Carney Michael
- Carpino Guido
- Carroll Peter R.
- Carter Candace
- Carvalho Andre L.
- Castle Erik
- Castro Patricia D.
- Catto James
- Cebulla Colleen M.
- Cernat Mircea
- Chabot John
- Chakravarty Debyani
- Chambwe Nyasha
- Chan June M.
- Chan Timothy A.
- Chandan Vishal
- Chang Kyle
- Chatila Walid K.
- Chemencedji Inga
- Chen Amy
- Chen Chu
- Chen Hu
- Chen Zhongyuan
- Cheng Feixiong
- Cherniack Andrew D.
- Chesla David
- Chevalier Simone
- Cheville John
- Cho Juok
- Chuah Eric
- Chudamani Sudha
- Chung Ki
- Cibulskis Carrie
- Clipca Adrian
- Colman Howard
- Cope Leslie
- Copland John A.
- Corcoran Niall
- Cordes Matthew G.
- Costello Tony
- Cottingham Sandra
- Couce Marta
- Covington Kyle
- Crain Daniel
- Cramer Daniel
- Creaney Jenette
- Creighton Chad J.
- Cuppini Lucia
- Curley Erin
- Cuzzubbo Stefania
- Czerniak Bogdan
- Danilova Ludmila
- Davis Amy
- de Bruijn Ino
- de Carvalho Ana C.
- de Krijger Ronald
- De Rienzo Assunta
- De Rose Agostino
- Defreitas Timothy
- Delman Keith
- Demchok John A.
- Desjardins Laurence
- Devine Karen
- Deyarmin Brenda
- Dhalla Noreen
- Dhanasekaran Renumathy
- Dhankani Varsha
- Dhir Rajiv
- Dimeco Francesco
- Ding Li
- Dinh Huyen
- Dinkin Mikhail
- Dipersio John
- Disaia Philip
- Doddapaneni Harshavardhan
- Donehower Lawrence A.
- Doruc Serghei
- Dos Santos Jose Sebastião
- Dottino Peter R.
- Drake Bettina
- Drummond Jennifer
- Drwiega Paul
- Dubina Michael
- Duell Rebecca
- Duffy Elizabeth R.
- Eckman John
- Edenfield W. Jeffrey
- Eijckenboom Wil
- Elder J. Bradley
- Engel Jay
- Eschbacher Jennifer
- Esmaeli Bita
- Evason Kimberley
- Facciolo Francesco
- Fan Cheng
- Fan Huihui
- Fantacone-Campbell J. Leigh
- Farnell Michael
- Farver Carol
- Fassnacht Martin
- Fehrenbach Ashley
- Felau Ina
- Feldman Michael
- Feltmate Colleen
- Ferguson Martin L.
- Finocchiaro Gaetano
- Flotte Thomas
- Fong Kwun M.
- Force Seth
- Forgie Ian
- Frazer Scott
- Fregnani José H.
- Fronick Catrina C.
- Fujimoto Junya
- Fulop Jordonna
- Fulton Lucinda A.
- Fulton Robert S.
- Gabra Hani
- Gabriel Stacey B.
- Galbraith Joseph
- Gao Galen F.
- Gao Jianjiong
- Gardner Johanna
- Gastier-Foster Julie M.
- Gaudio Eugenio
- Ge Zhongqi
- Gehlenborg Nils
- Gerken Mark
- Gershenwald Jeffrey
- Getz Gad
- Ghossein Ronald
- Giama Nasra
- Gibbs Richard A.
- Gilbert Sebastien
- Gillis Ad
- Gimenez-Roqueplo Anne-Paule
- Giné Eva
- Giordano Thomas
- Girard Nicolas
- Giuliante Felice
- Glenn Pat
- Glenn Robert
- Godwin Andrew K.
- Godwin Eryn M.
- Gonzalez Ana Maria Angulo
- Goodman Marc
- Gopalan Anuradha
- Goparaju Chandra
- Gorincioi Ghenadie
- Govindan Ramaswamy
- Graefen Markus
- Grazi Gianluca
- Grizzle William E.
- Gross Benjamin E.
- Guillermo Armando López
- Guo Charles
- Ha Gavin
- Haddad Andrea
- Hagedorn Curt H.
- Hale Walker
- Han Yi
- Hanh Phan Thi
- Hansen Paul
- Harr Jodi
- Hartmann Arndt
- Haydu Lauren
- Hayes D. Neil
- Hayward Nicholas
- Heath Sharon
- Hegde Apurva M.
- Heiman David I.
- Heins Zachary J.
- Henderson Joel
- Hermes Beth
- Hernandez Brenda
- Herold-Mende Christel
- Hersey Peter
- Hess Julian
- Hibshoosh Hanina
- Hilty Joe
- Hinoue Toshinori
- Ho Thai
- Hoadley Katherine A.
- Holt Robert
- Hooke Jeffrey A.
- Hoon Dave
- Horowitz Neil
- Houck John
- Hovens Christopher
- Hoyle Alan P.
- Hu Hai
- Hu Hai
- Hu Jianhong
- Huland Hartwig
- Hung Nguyen Phi
- Huntsman David
- Hutter Carolyn M.
- Iacocca Mary
- Ittmann Michael
- Jacobus Laura
- Jakrot Valerie
- Janssen Klaus-Peter
- Jefferys Stuart R.
- Jimeno Antonio
- Jones Corbin D.
- Jones Steven J. M.
- Ju Zhenlin
- Juhl Hartmut
- Jungk Christin
- Junker Kerstin
- Kakavand Hojabr
- Kalkanis Steven
- Kanchi Rupa S.
- Kandoth Cyriac
- Kang Koo Jeong
- Karlan Beth Y.
- Kasaian Katayoon
- Kasapi Melpomeni
- Kastl Alison
- Kebebew Electron
- Kefford Richard
- Kelley Robin K.
- Kemp Rafael
- Kendall Sara
- Kendler Ady
- Kendrick Michael
- Khuri Fadlo
- Kibel Adam
- Kim Jaegil
- Knijnenburg Theo
- Knudson Michael
- Knutson Tina
- Kocher Jean-Pierre
- Kohl Bernard
- Kopp Karla
- Korchina Viktoriya
- Korkut Anil
- Korpershoek Esther
- Korst Robert
- Kovatich Albert J.
- Kramer Roger
- Kucherlapati Melanie H.
- Kucherlapati Raju S.
- Kumar Bahavna
- Kundra Ritika
- Kvecher Leonid
- Kycler Witold
- La Konnor
- Lacombe Louis
- Ladanyi Marc
- Lai Phillip H.
- Laird Peter W.
- Landen Charles N.
- Landrum Lisa
- Lang James
- Larson Caroline
- Latour Mathieu
- Lau Kevin
- Lawrence Michael S.
- Lazar Alexander J.
- Le Xuan
- Lechan Ronald
- Lee Darlene
- Lee Jung Il
- Lee Kenneth
- Lee Sandra
- Lehman Norman L.
- Leighton Jake S.
- Leinonen Kalle
- Leraas Kristen M.
- Levine Douglas A.
- Lewis Lora
- Ley Timothy
- Li Jun
- Li Jun
- Li Wei
- Liang Han
- Liang Han
- Lichtenberg Tara M.
- Lin Pei
- Linehan W. Marston
- Ling Shiyun
- Lipp Eric
- Liptay Michael J.
- Liu Jia
- Liu Jianfang
- Liu Wenbin
- Liu Xiuping
- Liu Yuexin
- Logothetis Christopher
- Lohavanichbutr Pawadee
- Lolla Laxmi
- Long Georgina
- Longatto-Filho Adhemar
- Looijenga Leendert
- Lu Yiling
- Luketich James
- Luna Augustin
- Lyadov Vladimir
- Ma Deqin
- Ma Li
- Ma Yussanne
- Madan Rashna
- Maglinte Dennis T.
- Magliocca Kelly
- Maithel Shishir
- Mallery David
- Malykh Andrei
- Mandt Randy
- Manikhas George
- Mann Graham
- Mannel Robert
- Mannelli Massimo
- Mardis Elaine R.
- Mariamidze Armaz
- Mariani Odette
- Marino Mirella
- Marks Jeffrey
- Marra Marco A.
- Martignetti John A.
- Martin Julie
- Mattei Luca
- Mayo Michael
- Mccall Shannon
- Mcgraw Mary
- Mckercher Ginette
- Mclellan Michael D.
- Mclendon Roger
- Mcpherson Christopher
- Meier Sam
- Melamed Jonathan
- Meng Shaowu
- Meric-Bernstam Funda
- Merola Roberta
- Mes-Masson Anne-Marie
- Metwalli Adam R.
- Meyerson Matthew
- Mieczkowski Piotr A.
- Mikkelsen Tom
- Milhem Mohammed
- Miller Christopher A.
- Miller Judy
- Miller Michael
- Mills Gordon B.
- Mirsaidi Cyrus
- Moiseenko Fedor
- Moncrieff Marc
- Moore Kathleen
- Moore Richard A.
- Moran Cesar
- Morgan Margaret
- Morris Scott
- Morrison Carl
- Morton Donna
- Mose Lisle E.
- Moser Catherine
- Moxley Katherine
- Moyer Jeffey
- Mungall Andrew J.
- Mungall Karen
- Mura Sergiu
- Mural Richard J.
- Murawa Dawid
- Muto Michael
- Muzny Donna
- Myers Jerome
- Nagorney David
- Nair Praveen
- Naresh Rashi
- Naska Theresa
- Nelson Mark
- Ng Kwok-Shing
- Nguyen Phuong
- Nissan Moriah G.
- Noble Michael S.
- Noss Ardene
- Noushmehr Houtan
- O'Brien Daniel
- O'Neill Brian Patrick
- Ochoa Angelica
- Olabode Oluwole
- Olson Jeffrey J.
- Omberg Larsson
- Oosterhuis Wolter
- Ostrom Quinn T.
- Owonikoko Taofeek
- Pacak Karel
- Paklina Oxana
- Parfitt Jeremy
- Park Joong-Won
- Parker Joel S.
- Pass Harvey
- Patel Tushar
- Paulauskis Joseph
- Peng Xinxin
- Pennell Nathan A.
- Penny Robert
- Perin Alessandro
- Perou Amy H.
- Perou Charles M.
- Petersen Gloria
- Peterson Lisa
- Peto Myron
- Phillips Joanna
- Phillips Sarah M.
- Phu Bui Duc
- Piché Alain
- Pickens Alan
- Pihl Todd
- Pilarski Robert
- Pinero Edna M. Mora
- Pinto Peter A.
- Pirtac Maria
- Piwnica-Worms Helen
- Pollo Bianca
- Pool Mark
- Porten Sima
- Postier Russel
- Potapova Olga
- Powers James
- Prados Michael
- Prince Mark
- Que Florencia
- Quinn Michael
- Quintero-Aguilo Mario
- Rabeno Brenda
- Rai Karan
- Ramalingam Suresh
- Ramirez Nilsa C.
- Ramondetta Lois
- Rao Arvind
- Rassl Doris M.
- Rathmell W. Kimryn
- Raut Chandrajit P.
- Raymond Daniel
- Reis Rui M.
- Reuter Victor
- Reynolds Sheila
- Reznik Ed
- Rice David
- Richards William G.
- Rintoul Robert C.
- Rivera Michael
- Roach Jeffrey
- Roberts Lewis
- Robertson A. Gordon
- Robinson Bruce
- Roggin Kevin
- Roman-Roman Sergio
- Rosenthal Howard G.
- Rozek Laura
- Rubin Mark A.
- Ryan Michael
- Saad Fred
- Sadeghi Sara
- Saksena Gordon
- Sanchez-Vega Francisco
- Sander Chris
- Sankarankuty Ajith
- Santibanez Jireh
- Sastre Xavier
- Sauter Guido
- Saw Robyn
- Scapulatempo-Neto Cristovam
- Scarpace Lisa
- Schadendorf Dirk
- Schein Jacqueline E.
- Schiffman Mark
- Schilero Cathy
- Schlomm Thorsten
- Schmidt Heather K.
- Schmidt Laura S.
- Schoenfield Lynn
- Schultz Nikolaus
- Schumacher Steven E.
- Scolyer Richard
- Secord Angeles
- Seder Christopher W.
- Sekhon Harman
- Senecal Kelly
- Sepulveda Antonia
- Setdikova Galiya
- Sexton Katherine C.
- Shabunin Alexey
- Shannon Kerwin
- Sharp Alexis
- Shelley Carl Simon
- Shelton Candace
- Shelton Troy
- Shen Hui
- Sheridan Robert
- Sherman Mark
- Sheth Margi
- Shi Yan
- Shih Juliann
- Shimmel Kristen
- Shin Dong M.
- Shinbrot Eve
- Shipman Cassaundra
- Shmulevich Ilya
- Shriver Craig D.
- Shriver Craig D.
- Sica Gabriel
- Sifri Suzanne
- Sigmund Rita
- Signoretti Sabina
- Silveira Henrique C. S.
- Simko Jeffry
- Simon Ronald
- Simons Janae V.
- Singer Samuel
- Singh Bhuvanesh
- Singh Rosy
- Sipahimalani Payal
- Skelly Tara
- Sloan Andrew E.
- Slotta-Huspenina Julia
- Smallridge Robert
- Smith Jennifer
- Smith-McCune Karen
- Smolenski Kathy
- Smyrk Thomas
- Sofia Heidi J.
- Soloway Matthew G.
- Somiari Stella
- Sood Anil
- Spellman Paul
- Spillane Andrew
- Stancul Irina
- Stanton Melissa
- Staugaitis Susan M.
- Steele Ruth
- Stepa Serghei
- Stern Marc-Henri
- Stoehr Christine
- Stoehr Robert
- Stoop Hans
- Stretch Jonathan
- Stuart Joshua M.
- Su Tao
- Sumer S. Onur
- Sun Qiang
- Sun Yichao
- Sun Yutong
- Swanson Patricia
- Swisher Elizabeth
- Synott Maria
- Tam Angela
- Tamakawa Raina
- Tamboli Pheroze
- Tan Donghui
- Tang Yufang
- Tarnuzzer Roy
- Taubert Helge
- Tavobilov Mikhail
- Taylor Barry S.
- Tcaciuc Diana
- Tennstedt Pierre
- Thiessen Nina
- Thomas George
- Thompson Eric
- Thompson John
- Thompson R. Houston
- Thompson Timothy
- Thorp Richard
- Thorsson Vesteinn
- Tien Nguyen Viet
- Timmers Henri
- Tirapelli Daniela
- Tischler Arthur
- Torbenson Michael
- Troncoso Patricia
- Tsao Anne
- Tse Kane
- Tucker Kelinda
- Têtu Bernard
- Unterberg Andreas
- Urba Walter
- Valdivieso Federico
- Van Bang Nguyen
- Van Den Berg David J.
- van Kessel Kim E.
- Van Meir Erwin G.
- Van Tine Brian
- Vandenberg Scott
- Veluvolu Umadevi
- Vicha Ales
- Vidal Daniel O.
- Vocke Cathy D.
- Voet Doug
- von Deimling Andreas
- Voronina Olga
- Wach Sven
- Wakely Paul
- Waldmann Jens
- Walker Joan
- Wan Yunhu
- Wang Jing
- Wang Jioajiao
- Wang Linghua
- Wang Min
- Wang Timothy
- Wang Yumeng
- Wang Zhining
- Warnick Ronald
- Weinstein John N.
- Weisenberger Daniel J.
- Wentzensen Nicolas
- Westervelt Peter
- Wheeler David A.
- Wilkerson Matthew D.
- Williams Felicia
- Wilmott James
- Wilson Richard K.
- Wise Lisa
- Wistuba Ignacio
- Wiznerowicz Maciej
- Wolf Gregory
- Wolinsky Yingli
- Wong Christopher K.
- Wong Tina
- Worrell Robert
- Wu Ye
- Wullich Bernd
- Xi Liu
- Yang Hannah
- Yang Ian
- Yang Ju Dong
- Yang Liming
- Yao Fan
- Yau Christina
- Yena Peggy
- Zach Leigh Anne
- Zaren Howard
- Zelinka Tomas
- Zenklusen Jean C.
- Zhang Hailei
- Zhang Hongxin
- Zhang Hongzheng
- Zhang Huiwen
- Zhang Jiashan (Julia)
- Zhang Jiexin
- Zhang Lizhi
- Zhang Wei
- Zhao Fengmei
- Zhou Wanding
- Zmuda Erik
- Zuna Rosemary
- Zwarthoff Ellen C.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Protein ubiquitination is a dynamic and reversibleprocess of adding single ubiquitin molecules orvarious ubiquitin chains to target proteins. Here,using multidimensional omic data of 9,125 tumorsamples across 33 cancer types from The CancerGenome Atlas, we perform comprehensive molecu-lar characterization of 929 ubiquitin-related genesand 95 deubiquitinase genes. Among them, we sys-tematically identify top somatic driver candidates,including mutatedFBXW7with cancer-type-specificpatterns and amplifiedMDM2showing a mutuallyexclusive pattern withBRAFmutations. Ubiquitinpathway genes tend to be upregulated in cancermediated by diverse mechanisms. By integratingpan-cancer multiomic data, we identify a group oftumor samples that exhibit worse prognosis. Thesesamples are consistently associated with the upre-gulation of cell-cycle and DNA repair pathways, char-acterized by mutatedTP53,MYC/TERTamplifica-tion, andAPC/PTENdeletion. Our analysishighlights the importance of the ubiquitin pathwayin cancer development and lays a foundation fordeveloping relevant therapeutic strategies
Erratum: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- Abate Degu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdela Jemal
- Abdelalim Ahmed
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Molla
- Abebe Zegeye
- Abera Semaw Ferede
- Abil Olifan Zewdie
- Abraha Haftom Niguse
- Abu Raddad Laith J
- Abun Rmeileh Niveen M.E
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Pawan
- Adamu Abdu Abdullahi
- Adane Akilew Awoke
- Adebayo Oladimeji
- Adedoyin Rufus Adesoji
- Adekanmbi Victor T
- Ademi Zanfina
- Adetokunboh Olatunji O
- Adib Mina G
- Admasie Amha
- Adsuar Jose C
- Afanvi Kossivi Agbélénko
- Afarideh Mohsen
- Afshin Ashkan
- Agarwal Gina
- Aggarwal Anju
- Aghayan Sargis A
- Agrawal Anurag
- Agrawal Sutapa
- Ahmadi Moghadam M
- Ahmadi Alireza
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
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- Touvier Mathilde
- Tovani Palone Marcos Roberto
- Towbin Jeffrey A
- Tran Bach Xuan
- Tran Khanh Bao
- Truelsen Thomas Clement
- Truong Nu Thi
- Tsadik Afewerki Gebremeskel
- Tudor Car Lorainne
- Tuzcu E. Murat
- Tymeson Hayley D
- Tyrovolas Stefanos
- Ukwaja Kingsley N
- Ullah Irfan
- Updike Rachel L
- Usman Muhammad Shariq
- Uthman Olalekan A
- Vaduganathan Muthiah
- Vaezi Afsane
- Valdez Pascual Rubén
- van Donkelaar Aaron
- Varavikova Elena A
- Varughese Santosh
- Vasankari Tommi Juhani
- Venkateswaran Vidhya
- Venketasubramanian Narayanaswamy
- Villafaina Santos
- Violante Francesco Saverio
- Vladimirov Sergey K
- Vlassov Vasiliy Victorovich
- Vollset Stein Emil
- Vos Theo
- Vosoughi Kia
- Vu Giang Thu
- Vujčić Isidora S
- Wagnew Fasil Shiferaw
- Waheed Yasir
- Waller Stephen G
- Walson Judd L
- Wang Yafeng
- Wang Yanping
- Wang Yuan Pang
- Weiderpass Elisabete
- Weintraub Robert G
- Weldegebreal Fitsum
- Werdecker Andrea
- Werkneh Adhena Ayaliew
- West James Jason
- Westerman Ronny
- Whiteford Harvey A
- Widecka Justyna
- Wijeratne Tissa
- Winkler Andrea Sylvia
- Wiyeh Alison Beriliy
- Wiysonge Charles Shey
- Wong Tienyin
- Wu Shouling
- Wu Shouling
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yadollahpour Ali
- Yahyazadeh Jabbari Seyed Hossein
- Yamada Tomohide
- Yan Lijing L
- Yano Yuichirou
- Yaseri Mehdi
- Yasin Yasin Jemal
- Yeshaneh Alex
- Yimer Ebrahim M
- Yip Paul S.F
- Yisma Engida
- Yonemoto Naohiro
- Yoon Seokjun
- Yotebieng Marcel
- Younis Mustafa Z.“Mike”
- Yousefifard Mahmoud
- Yu Chuanhua
- Zaidi Zoubida
- Zaman Sojib Bin
- Zamani Mohammad
- Zavala-Arciniega Luis
- Zhang Anthonylin
- Zhang Hao
- Zhang Kai
- Zhou Maigeng
- Zimsen Stephanie R.M
- Zodpey Sanjay P
- Øverland Simon
- Šantrić Milićević Milena M.M
- Šekerija Mario
- Publication venue
- 'Elsevier BV'
- Publication date
- 28/06/2019
- Field of study
Interpretation: By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning
Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud Morad
- Aad Georges
- Abbott Brad
- Abdinov Ovsat
- Abeloos Baptiste
- Abidi Syed
- AbouZeid Ossama
- Abraham Nicola
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby
- Adachi Shunsuke
- Adamczyk Leszek
- Adelman Jahred
- Adersberger Michael
- Adye Tim
- Affolder Tony
- Afik Yoav
- Agatonovic-Jovin Tatjana
- Agheorghiesei Catalin
- Aguilar-Saavedra Juan
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akatsuka Shunichi
- Akerstedt Henrik
- Akilli Ece
- Akimov Andrei
- Alberghi Gian
- Albert Justin
- Albicocco Pietro
- Alconada Verzini Maria
- Alderweireldt Sara
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Ali Babar
- Aliev Malik
- Alimonti Gianluca
- Alison John
- Alkire Steven
- Allbrooke Benedict
- Allen Benjamin
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Alshehri Azzah
- Alstaty Mahmoud
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazia
- Amadio Brian
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana
- Amoroso Simone
- Anastopoulos Christos
- Ancu Lucian
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders John
- Anderson Kelby
- Andreazza Attilio
- Andrei George
- Angelidakis Stylianos
- Angelozzi Ivan
- Angerami Aaron
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antel Claire
- Antonelli Mario
- Antonov Alexey
- Antrim Daniel
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
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- Araujo Ferraz Victor
- Arce Ayana
- Ardell Rose
- Arduh Francisco
- Arguin Jean-Francois
- Argyropoulos Spyridon
- Arik Metin
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- Armitage Lewis
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- Barreiro Fernando
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- Biebel Otmar
- Biedermann Dustin
- Bielski Rafal
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- Biglietti Michela
- Billoud Thomas
- Bilokon Halina
- Bindi Marcello
- Bingul Ahmet
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- Bisanz Tobias
- Bittrich Carsten
- Bjergaard David
- Black James
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- Blue Andrew
- Blumenschein Ulrike
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- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona
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- Boehler Michael
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- Bogavac Danijela
- Bogdanchikov Alexander
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- Büscher Daniel
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- C-Q Changqiao
- Cabrera Urbán Susana
- Caforio Davide
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- Calvet David
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- Caminal Armadans Roger
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- Carbone Ryne
- Cardarelli Roberto
- Cardillo Fabio
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- Carlson Benjamin
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- Caron Sascha
- Carquin Edson
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- Carrá Sonia
- Casadei Diego
- Casado Maria
- Casha Albert
- Casolino Mirkoantonio
- Casper David
- Castelijn Remco
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- Castro Nuno
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- Cavaliere Viviana
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- Cavasinni Vincenzo
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- Chan Wing
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- Charlton Dave
- Chau Chav
- Chavez Barajas Carlos
- Che Siinn
- Cheatham Susan
- Chegwidden Andrew
- Chekanov Sergei
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- Chelkov Gueorgui
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- Chen Cheng
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- Chen Jing
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- Chen Xin
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- Cheng Hok
- Cheng Huajie
- Cheplakov Alexander
- Cheremushkina Evgeniya
- Cherkaoui El Moursli Rajaa
- Cheu Elliott
- Cheung Kingman
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Chiodini Gabriele
- Chisholm Andrew
- Chitan Adrian
- Chiu Yu
- Chizhov Mihail
- Choi Kyungeon
- Chomont Arthur
- Chouridou Sofia
- Chow Yun
- Christodoulou Valentinos
- Chu Ming
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
- Ciftci Abbas
- Cinca Diane
- Cindro Vladimir
- Cioara Irina
- Ciocio Alessandra
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- Citron Zvi
- Citterio Mauro
- Ciubancan Mihai
- Clark Allan
- Clark Brian
- Clark Michael
- Clark Philip
- Clarke Robert
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James
- Colasurdo Luca
- Cole Brian
- Colijn Auke-Pieter
- Collot Johann
- Colombo Tommaso
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon
- Connelly Ian
- Constantinescu Serban
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
- Cooper-Sarkar Amanda
- Cormier Felix
- Cormier Kyle
- Corradi Massimo
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- Cortes-Gonzalez Arely
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- Cowan Glen
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- Cree Graham
- Crescioli Francesco
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- Cristinziani Markus
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- Cueto Ana
- Cuhadar Donszelmann Tulay
- Cukierman Aviv
- Cummings Jane
- Curatolo Maria
- Czekierda Sabina
- Czodrowski Patrick
- Cúth Jakub
- D'amen Gabriele
- D'Auria Saverio
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- D'Onofrio Monica
- Da Cunha Sargedas De Sousa Mario
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- Dabrowski Wladyslaw
- Dado Tomas
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- Dale Orjan
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- Dallapiccola Carlo
- Dam Mogens
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- de Asmundis Riccardo
- De Benedetti Abraham
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- Godlewski Jan
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- Yamanaka Takashi
- Yamane Fumiya
- Yamatani Masahiro
- Yamazaki Tomohiro
- Yamazaki Yuji
- Yan Zhen
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- Yao Weiming
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- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanzi Daniele
- Zeitnitz Christian
- Zemaityte Gabija
- Zemla Andrzej
- Zeng Jian
- Zeng Qi
- Zenin Oleg
- Zerwas Dirk
- Zhang Dengfeng
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Liqing
- Zhang Matt
- Zhang Peng
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Yu
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhou Bing
- Zhou Chen
- Zhou Li
- Zhou Maosen
- Zhou Mingliang
- Zhou Ning
- Zhou You
- Zhu Cheng
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- Zou Rui
- zur Nedden Martin
- Zwalinski Lukasz
- Åkesson Torsten
- Šfiligoj Tina
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belmont Iii Ronald John
- Belmont Moreno Ernesto
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Berceanu Ionela
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
- Bertens Redmer Alexander
- Berzano Dario
- Betev Latchezar
- Bhasin Anju
- Bhat Inayat Rasool
- Bhati Ashok Kumar
- Bhattacharjee Buddhadeb
- Bhom Jihyun
- Bianchi Livio
- Bianchi Nicola
- Bianchin Chiara
- Bielcik Jaroslav
- Bielcikova Jana
- Bilandzic Ante
- Biswas Rathijit
- Biswas Saikat
- Bjelogrlic Sandro
- Blair Justin Thomas
- Blau Dmitry
- Blume Christoph
- Bock Friederike
- Boettger Stefan
- Bogdanov Alexey
- Boggild Hans
- Boldizsar Laszlo
- Bombara Marek
- Book Julian Heinz
- Borel Herve
- Borissov Alexander
- Borri Marcello
- Bossu Francesco
- Botta Elena
- Bourjau Christian
- Braun-Munzinger Peter
- Bregant Marco
- Breitner Timo Gunther
- Broker Theo Alexander
- Browning Tyler Allen
- Broz Michal
- Brucken Erik Jens
- Bruna Elena
- Bruno Giuseppe Eugenio
- Budnikov Dmitry
- Buesching Henner
- Bufalino Stefania
- Buncic Predrag
- Busch Oliver
- Buthelezi Edith Zinhle
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- Yaldo Chris G
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- Yang Ping
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- Yokoyama Hiroki
- Yoo In-Kwon
- Yoon Jin Hee
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
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- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
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- Zhu Hongsheng
- Zhu Jianhui
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- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 14/09/2015
- Field of study
We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
Forward-central two-particle correlations in p-Pb collisions at root s(NN)=5.02 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aimo Ilaria
- Aiola Salvatore
- Ajaz Muhammad
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Armesto Perez Nestor
- Arnaldi Roberta
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Bach Matthias Jakob
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baltasar Dos Santos Pedrosa Fernando
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
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- Yaldo Chris G
- Yang Hongyan
- Yang Ping
- Yano Satoshi
- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In-Kwon
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
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- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Chunhui
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
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- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 26/06/2015
- Field of study
Two-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 2GeV/c. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B. V.Peer reviewe
Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions at root(NN)-N-S=2.76 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aimo Ilaria
- Aiola Salvatore
- Ajaz Muhammad
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Armesto Perez Nestor
- Arnaldi Roberta
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Bach Matthias Jakob
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
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- Zyzak Maksym
- Publication venue
- Publication date
- 22/07/2015
- Field of study
Peer reviewe
Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.
- Author
- Amin N. (Najaf)
- Arepalli S. (Sampath)
- Barker R.A. (Roger)
- Ben-Shlomo Y.
- Berendse H.W. (Henk W.)
- Berg D. (Daniela)
- Bettella F. (Francesco)
- Bhatia K.P. (Kailash)
- Bie R.M.A. (Rob) de
- Biffi A. (Alessandro)
- Blauwendraat C. (Cornelis)
- Bloem B.R. (Bastiaan)
- Bochdanovits Z. (Zoltan)
- Bonin M. (Malte) von
- Botia J.A. (Juan A.)
- Brice A. (Alexis)
- Brockmann K.
- Brooks J. (Janet)
- Burn D.J. (David)
- Caroline H Williams-Gray
- Castillo-Lizardo M. (Melissa)
- Charlesworth K. (Kate)
- Chen H. (Honglei)
- Chinnery P.F. (Patrick F.)
- Chong S. (Sean)
- Chouhan A.K. (Amit K.)
- Clarke C.E. (Carl E.)
- Cookson M.R. (Mark)
- Cooper J.M. (J Mark)
- Corvol J.C. (Jean-Christophe)
- Counsell C. (Carl)
- Damier P. (Philippe)
- Dartigues J.-F.
- David D.C. (Della C.)
- Deloukas P. (Panagiotis)
- Deuschl G. (Günther)
- Dexter D.T. (David)
- Dijk K.D. (Karin) van
- Dillman A. (Allissa)
- Dong J. (Jing)
- Drouet V. (Valérie)
- Duijn C.M. (Cornelia) van
- Durif F. (Frank)
- Dürr A. (Alexandra)
- Edkins T. (Ted)
- Escott-Price V. (Valentina)
- Evans J. (Jonathan Mark)
- Foltynie T. (Thomas)
- Gardner M. (Mac)
- Gasser T. (Thomas)
- Gibbs J.R. (J.Raphael)
- Goate A.M. (Alison)
- Gray E. (Emma)
- Guerreiro R. (Rita)
- Hardy J. (John)
- Harris C. (Clare)
- Heetveld S. (Sasja)
- Hernandez D.G. (Dena)
- Heutink P. (Peter)
- Hilten J.J. (Jacobus) van
- Hofman A. (Albert)
- Hollenbeck J.R. (John R.)
- Holton J.L. (Janice)
- Hu M. (Michele)
- Huang X. (Xiaohong)
- Hudson G. (Gavin)
- Hunt S.E. (Sarah E.)
- Illig T. (Thomas)
- Jain A. (Ashok)
- Jansen I. (Iris)
- Javier Simón-Sánchez
- Jose M Bras
- Jónsson P.V. (Pálmi)
- Lambert J.-C.
- Langford C. (Cordelia)
- Lechler M.C. (Marie C.)
- Lees A.J. (Andrew)
- Lesage S. (Suzanne)
- Li Y. (Yarong)
- Lichtner P. (Peter)
- Limousin P. (Patricia)
- Lopez G.
- Lorenz D. (Delia)
- Lubbe S. (Steven)
- Lubbe S.J. (Steven J.)
- Lungu C. (Codrin)
- Majounie E. (Elisa)
- Martinez M. (Maria)
- McNeill N.H. (Nathan)
- Michels H. (Helen)
- Moorby C. (Catriona)
- Moore M. (Matt)
- Morris H.R. (Huw R.)
- Mudanohwo E. (Ese)
- Mätzler W. (Walter)
- Nalls M.A. (Michael)
- Nicholas W Wood
- Nicolas A. (Aude)
- Nollen E.A. (Ellen A.)
- O'Sullivan S.S. (Sean)
- Pearson J. (Justin)
- Perlmutter J.S. (Joel)
- Plagnol V. (Vincent)
- Pollak P. (Pierre)
- Post B. (Bart)
- Potter S.C. (Simon)
- Price R. (Ryan)
- Pétursson H. (Hjörvar)
- Revesz T. (Tamas)
- Riess O. (Olaf)
- Rivadeneira Ramirez F. (Fernando)
- Rizzu P. (Patrizia)
- Ryten M. (Mina)
- Saad M. (Mohamad)
- Sawcer S.J. (Stephen)
- Schapira A. (Anthony)
- Scheffer H. (Hans)
- Schulte C. (Claudia)
- Seinstra R.I. (Renée I.)
- Sharma M.
- Shaw K. (Karen)
- Sheerin U.-M. (Una-Marie)
- Shoulson I. (Ira)
- Shulman J.M.
- Shulman L. (Lee)
- Simón-Sánchez J. (Javier)
- Singleton A. (Andrew)
- Singleton A. (Andrew)
- Smith C. (Colin)
- Spencer C.C.A. (Chris C.)
- Stefansson H. (Hreinn)
- Stockton J.D. (Joanna D.)
- Strange A. (Amy)
- Sveinbjörnsdóttir S. (Sigurlaug)
- Talbot D.
- Tanner C.M. (Carlie)
- Tashakkori-Ghanbaria A. (Avazeh)
- Tison F. (François)
- Trabzuni D. (Danyah)
- Traynor B.J. (Bryan)
- Uitterlinden A.G. (André)
- Vandrovcova J. (Jana)
- Velseboer D. (Daan)
- Vidailhet M. (M.)
- Walker R. (Robert)
- Warrenburg B. (Bart) van de
- Wickremaratchi M. (Mirdhu)
- Williams N. (Nigel)
- Winder-Rhodes S. (Sophie)
- Wurster K.D. (Kathrin)
- Ye H. (Hui)
- Yogi P. (Puja)
- Zwart J-A. (John-Anker)
- Publication venue
- Genome Biol
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: Whole-exome sequencing (WES) has been successful in identifying genes that cause familial Parkinson's disease (PD). However, until now this approach has not been deployed to study large cohorts of unrelated participants. To discover rare PD susceptibility variants, we performed WES in 1148 unrelated cases and 503 control participants. Candidate genes were subsequently validated for functions relevant to PD based on parallel RNA-interference (RNAi) screens in human cell culture and Drosophila and C. elegans models. RESULTS: Assuming autosomal recessive inheritance, we identify 27 genes that have homozygous or compound heterozygous loss-of-function variants in PD cases. Definitive replication and confirmation of these findings were hindered by potential heterogeneity and by the rarity of the implicated alleles. We therefore looked for potential genetic interactions with established PD mechanisms. Following RNAi-mediated knockdown, 15 of the genes modulated mitochondrial dynamics in human neuronal cultures and four candidates enhanced α-synuclein-induced neurodegeneration in Drosophila. Based on complementary analyses in independent human datasets, five functionally validated genes-GPATCH2L, UHRF1BP1L, PTPRH, ARSB, and VPS13C-also showed evidence consistent with genetic replication. CONCLUSIONS: By integrating human genetic and functional evidence, we identify several PD susceptibility gene candidates for further investigation. Our approach highlights a powerful experimental strategy with broad applicability for future studies of disorders with complex genetic etiologies
Centrality evolution of the charged-particle pseudorapidity density over a broad pseudorapidity range in Pb-Pb collisions at root s(NN)=2.76TeV
- Author
- Adam Jaroslav
- Adam Jaroslav
- Adamová Dagmar
- Adamová Dagmar
- Aggarwal Madan Mohan
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agnello Michelangelo
- Agrawal Neelima
- Agrawal Neelima
- Ahammed Zubayer
- Ahammed Zubayer
- Ahn Sang Un
- Ahn Sang Un
- Aiola Salvatore
- Aiola Salvatore
- Akindinov Alexander
- Akindinov Alexander
- Alam Sk Noor
- Alam Sk Noor
- Aleksandrov Dmitry
- Aleksandrov Dmitry
- Alessandro Bruno
- Alessandro Bruno
- Alexandre Didier
- Alexandre Didier
- Alfaro Molina Jose Ruben
- Alfaro Molina Jose Ruben
- Alici Andrea
- Alici Andrea
- Alkin Anton
- Alkin Anton
- Almaraz J.R.M.
- Almaraz J.R.M.
- Alme Johan
- Alme Johan
- Alt Torsten
- Alt Torsten
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- Altinpinar Sedat
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- Altsybeev Igor
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- Andrei Cristian
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- Andronic Anton
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- Hwang D.S.
- Hwang D.S.
- Ilkaev Radiy
- Ilkaev Radiy
- Inaba Motoi
- Inaba Motoi
- Ippolitov Mikhail
- Ippolitov Mikhail
- Irfan M.
- Irfan M.
- Ivanov Marian
- Ivanov Marian
- Ivanov V.
- Ivanov V.
- Izucheev Vladimir
- Izucheev Vladimir
- Jacobs Peter Martin
- Jacobs Peter Martin
- Jadhav Manoj Bhanudas
- Jadhav Manoj Bhanudas
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- Jadlovsky Jan
- Jadlovsky Jan
- Jahnke Cristiane
- Jahnke Cristiane
- Jakubowska Monika Joanna
- Jakubowska Monika Joanna
- Jang Haeng Jin
- Jang Haeng Jin
- Janik Malgorzata Anna
- Janik Malgorzata Anna
- Jayarathna Pahula Hewage Sandun Yasassri
- Jayarathna Pahula Hewage Sandun Yasassri
- Jena Chitrasen
- Jena Chitrasen
- Jena Satyajit
- Jena Satyajit
- Jiménez Bustamante Raúl Tonatiuh
- Jiménez Bustamante Raúl Tonatiuh
- Jones Peter Graham
- Jones Peter Graham
- Jung H.
- Jung H.
- Jusko Anton
- Jusko Anton
- Kalinak Peter
- Kalinak Peter
- Kalweit Alexander Philipp
- Kalweit Alexander Philipp
- Kamin Jason Adrian
- Kamin Jason Adrian
- Kang Ju Hwan
- Kang Ju Hwan
- Kaplin Vladimir
- Kaplin Vladimir
- Kar Somnath
- Kar Somnath
- Karasu Uysal Ayben
- Karasu Uysal Ayben
- Karavichev Oleg V.
- Karavichev Oleg V.
- Karavicheva Tatiana L.
- Karavicheva Tatiana L.
- Karayan Lilit
- Karayan Lilit
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- Karpechev Evgeny
- Kebschull Udo
- Kebschull Udo
- Keidel Ralf
- Keidel Ralf
- Keijdener Darius Laurens D.
- Keijdener Darius Laurens D.
- Keil Markus
- Keil Markus
- Khan P.
- Khan P.
- Khan Shuaib Ahmad
- Khan Shuaib Ahmad
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- Khanzadeev Alexei
- Kharlov Yury
- Kharlov Yury
- Kileng Bjarte
- Kileng Bjarte
- Kim D.
- Kim D.
- Kim D.J.
- Kim D.J.
- Kim D.W.
- Kim D.W.
- Kim H.
- Kim H.
- Kim J.S.
- Kim J.S.
- Kim M.
- Kim M.
- Kim M.
- Kim M.
- Kim S.
- Kim S.
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- Kim T.
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- Kirsch Stefan
- Kisel Ivan
- Kisel Ivan
- Kiselev Sergej N.
- Kiselev Sergej N.
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- Kisiel Adam Ryszard
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- Kiss Gabor
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- Klay Jennifer Lynn
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- Klein Carsten
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- Klein Jochen
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- Kluge Alexander
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- Knichel Michael Linus
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- Kobayashi Taiyo
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- Kobdaj Chinorat
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- Kollegger Thorsten
- Kolojvari Anatoly
- Kolojvari Anatoly
- Kondratiev Valery P.
- Kondratiev Valery P.
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- Koyithatta Meethaleveedu Greeshma
- Koyithatta Meethaleveedu Greeshma
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- Krizek Filip
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- Krzewicki Mikolaj
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- Kubera Andrew Michael
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- Kweon Min Jung
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- Leeuwen Marco van
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- Lemmon Roy Crawford
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- León Monzón Ildefonso
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- Li X.
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- Lisa Michael A.
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- Ljunggren Hans Martin
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- Lowe Andrew John
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- Malaev Mikhail
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- Zhigareva Natalia
- Zhigareva Natalia
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- Šumbera Michal
- Šumbera Michal
- Šándor Ladislav
- Šándor Ladislav
- Publication venue
- Publication date
- 14/09/2015
- Field of study
Peer reviewe
Pseudorapidity and transverse-momentum distributions of charged particles in proton-proton collisions at root s=13 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Balasubramanian Supraja
- Baldisseri Alberto
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belmont Iii Ronald John
- Belmont Moreno Ernesto
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Berceanu Ionela
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
- Bertens Redmer Alexander
- Berzano Dario
- Betev Latchezar
- Bhasin Anju
- Bhat Inayat Rasool
- Bhati Ashok Kumar
- Bhattacharjee Buddhadeb
- Bhom Jihyun
- Bianchi Livio
- Bianchi Nicola
- Bianchin Chiara
- Bielcik Jaroslav
- Bielcikova Jana
- Bilandzic Ante
- Biswas Rathijit
- Biswas Saikat
- Bjelogrlic Sandro
- Blair Justin Thomas
- Blau Dmitry
- Blume Christoph
- Bock Friederike
- Boettger Stefan
- Bogdanov Alexey
- Boggild Hans
- Boldizsar Laszlo
- Bombara Marek
- Book Julian Heinz
- Borel Herve
- Borissov Alexander
- Borri Marcello
- Bossu Francesco
- Botta Elena
- Bourjau Christian
- Braun-Munzinger Peter
- Bregant Marco
- Breitner Timo Gunther
- Broker Theo Alexander
- Browning Tyler Allen
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- Buthelezi Edith Zinhle
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- Caffarri Davide
- Cai Xu
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- Calero Diaz Liliet
- Caliva Alberto
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- Camerini Paolo
- Carena Francesco
- Carena Wisla
- Carnesecchi Francesca
- Castillo Castellanos Javier Ernesto
- Castro Andrew John
- Casula Ester Anna Rita
- Ceballos Sanchez Cesar
- Cepila Jan
- Cerello Piergiorgio
- Cerkala Jakub
- Chang Beomsu
- Chapeland Sylvain
- Chartier Marielle
- Charvet Jean-Luc Fernand
- Chattopadhyay Subhasis
- Chattopadhyay Sukalyan
- Chelnokov Volodymyr
- Cherney Michael Gerard
- Cheshkov Cvetan Valeriev
- Cheynis Brigitte
- Chibante Barroso Vasco Miguel
- Cho Soyeon
- Chochula Peter
- Choi Kyungeon
- Chojnacki Marek
- Choudhury Subikash
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter
- Chujo Tatsuya
- Chung Suh-Urk
- Chunhui Zhang
- Cicalo Corrado
- Cifarelli Luisa
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- Deisting Alexander
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- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
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- Zhu Hongsheng
- Zhu Jianhui
- Zichichi Antonino
- Zimmermann Alice
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 29/09/2015
- Field of study
The pseudorapidity (eta) and transverse-momentum (p(T)) distributions of charged particles produced in proton-proton collisions are measured at the centre-of-mass energy root s = 13 TeV. The pseudorapidity distribution in vertical bar eta vertical bar <1.8 is reported for inelastic events and for events with at least one charged particle in vertical bar eta vertical bar <1. The pseudorapidity density of charged particles produced in the pseudorapidity region vertical bar eta vertical bar <0.5 is 5.31 +/- 0.18 and 6.46 +/- 0.19 for the two event classes, respectively. The transverse-momentum distribution of charged particles is measured in the range 0.15 <p(T) <20 GeV/c and vertical bar eta vertical bar <0.8 for events with at least one charged particle in vertical bar eta vertical bar <1. The evolution of the transverse momentum spectra of charged particles is also investigated as a function of event multiplicity. The results are compared with calculations from PYTHIA and EPOS Monte Carlo generators. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
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