141 research outputs found
A Proteomic and Cellular Analysis of Uropods in the Pathogen Entamoeba histolytica
- Author
- A Aguilar-Rojas
- AM Lechner
- Anuradha Lohia
- BN Mitra
- C Banuelos
- C Martinez-Lopez
- CG Clark
- CH Gonzalez De la Rosa
- Christian Weber
- Chung-Chau Hon
- D Bansal
- Daniela Faust
- E Coudrier
- E Ficko-Blean
- E Gonzalez
- E Labruyere
- E Orozco
- E Raz
- F Girard-Misguich
- F Sanchez-Madrid
- G Garcia-Rivera
- GC Roberts
- H Irmer
- H JWong
- J Calderon
- J Santi-Rocca
- Jacques Marquay Markiewicz
- JH Lee
- K Ginalski
- L Blanchoin
- LA Baxt
- LA Baxt
- LE Arias-Romero
- LE Arias-Romero
- LS Diamond
- M Espinosa-Cantellano
- M Tillack
- M Vargas
- MD Abd-Alla
- MP Barrios-Ceballos
- MS Bretscher
- MS Bretscher
- N Guillen
- Nancy Guillen
- P Arhets
- P Arhets
- P Tavares
- P Tavares
- R Bracha
- R Haque
- RC MacFarlane
- RG Fehon
- RR Vines
- S Ankri
- S Blazquez
- S Blazquez
- S Ghosh
- S Marion
- S Marion
- S Pan
- SM Reynolds
- SN Buss
- Sylvie Syan
- T Jacobs
- T Lauwaet
- U Edman
- WA Petri Jr
- XJ Cheng
- XJ Cheng
- XY Wang
- Y Hou
- Z Jevnikar
- Z Jevnikar
- Z Mai
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Exposure of Entamoeba histolytica to specific ligands induces cell polarization via the activation of signalling pathways and cytoskeletal elements. The process leads to formation of a protruding pseudopod at the front of the cell and a retracting uropod at the rear. In the present study, we show that the uropod forms during the exposure of trophozoites to serum isolated from humans suffering of amoebiasis. To investigate uropod assembly, we used LC-MS/MS technology to identify protein components in isolated uropod fractions. The galactose/N-acetylgalactosamine lectin, the immunodominant antigen M17 (which is specifically recognized by serum from amoeba-infected persons) and a few other cells adhesion-related molecules were primarily involved. Actin-rich cytoskeleton components, GTPases from the Rac and Rab families, filamin, α-actinin and a newly identified ezrin-moesin-radixin protein were the main factors found to potentially interact with capped receptors. A set of specific cysteine proteases and a serine protease were enriched in isolated uropod fractions. However, biological assays indicated that cysteine proteases are not involved in uropod formation in E. histolytica, a fact in contrast to the situation in human motile immune cells. The surface proteins identified here are testable biomarkers which may be either recognized by the immune system and/or released into the circulation during amoebiasis
RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro
- Author
- A Buil
- A Hammarstedt
- A Varshney
- AE Justice
- AS Rocha
- AT Turer
- BB Sun
- C Christodoulides
- C Fuerer
- C Giambartolomei
- D Shungin
- D Wiederschain
- E Arner
- E Jeffery
- E Jeffery
- F Caux
- G Greicius
- GC Rivera-Gonzalez
- GT Consortium
- H Clevers
- H Guo
- I Surakka
- J Hilkens
- J Sanchez-Gurmaches
- J Sanchez-Gurmaches
- J Wakefield
- J Yang
- JE Minchin
- JEN Minchin
- JEN Minchin
- KA Kim
- KE Pinnick
- KH Willert
- KL Spalding
- KN Manolopoulos
- L Planas-Paz
- LA Lotta
- M Civelek
- M Lonn
- M Sigal
- M Todorcevic
- M Wabitsch
- MD Jensen
- MD Robinson
- MJ Lindhurst
- MJ Lindhurst
- N Barker
- NY Loh
- O Kazanskaya
- QA Wang
- RK Gupta
- RK Semple
- RN Kettleborough
- S George
- SK McMenamin
- SL Pulit
- SM Kim
- T Sato
- T Tchkonia
- U Styrkarsdottir
- V Krishnan
- V Vidal
- W de Lau
- X Rong
- Y Zhou
- YD Tchoukalova
- Zhifen Chen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 03/06/2020
- Field of study
Fat distribution is an independent cardiometabolic risk factor. However, its molecular and cellular underpinnings remain obscure. Here we demonstrate that two independent GWAS signals at RSPO3, which are associated with increased body mass index-adjusted waist-to-hip ratio, act to specifically increase RSPO3 expression in subcutaneous adipocytes. These variants are also associated with reduced lower-body fat, enlarged gluteal adipocytes and insulin resistance. Based on human cellular studies RSPO3 may limit gluteofemoral adipose tissue (AT) expansion by suppressing adipogenesis and increasing gluteal adipocyte susceptibility to apoptosis. RSPO3 may also promote upper-body fat distribution by stimulating abdominal adipose progenitor (AP) proliferation. The distinct biological responses elicited by RSPO3 in abdominal versus gluteal APs in vitro are associated with differential changes in WNT signalling. Zebrafish carrying a nonsense rspo3 mutation display altered fat distribution. Our study identifies RSPO3 as an important determinant of peripheral AT storage capacity
Massive horizontal gene transfer, strictly vertical inheritance and ancient duplications differentially shape the evolution of Bacillus cereus enterotoxin operons hbl, cytK and nhe
- Author
- A Fagerlund
- A Fagerlund
- A Gurevich
- A Rejasse
- A Sorokin
- AE Darling
- AM Gaviria Rivera
- AR Hoffmaster
- B Cardazzo
- C Ash
- C Brezillon
- C Cadot
- CC Thompson
- Christopher Huptas
- CS Han
- D Kantas
- D Phung
- DH Huson
- DJ Beecher
- DJ Beecher
- DP Martin
- E Guillemet
- E Helgason
- E Helgason
- E Helgason
- E Oltuszak-Walczak
- EV Koonin
- F Sievers
- FA Drobniewski
- FM Hoton
- G Jimenez
- GC Frankland
- H Agaisse
- HA Hong
- I Swiecicka
- I Swiecicka
- J Goris
- JG Lawrence
- JM Gonzalez Jr
- JT Simpson
- K Tamura
- K Tamura
- KP Francis
- KS Ko
- L Slamti
- L Slamti
- L Thorsen
- L Thorsen
- LH Duc
- LK Nakamura
- LK Nakamura
- LO Ticknor
- LP Stenfors
- LP Stenfors Arnesen
- LP Stenfors Arnesen
- M Ehling-Schulz
- M Ganash
- M Gohar
- M Kim
- M Richter
- MA Ragan
- Maria-Elisabeth Böhm
- MG Murray
- MH Guinebretiere
- MH Guinebretiere
- MH Guinebretiere
- MK Dommel
- N Declerck
- NJ Tourasse
- NJ Tourasse
- NT Hoa
- OA Okstad
- PH Damgaard
- PS Novichkov
- R Chikhi
- R Koch
- R Kuroki
- RK Patel
- S Lechner
- SG Bavykin
- SH Beattie
- Siegfried Scherer
- SN Gardner
- SR Klee
- T Lindback
- T Lindback
- T Lund
- U Heilkenbrinker
- Viktoria Magdalena Krey
- VM Doll
- X Hu
- X Hu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study
- Author
- Abduljalal M
- Abdullaev AA
- Abdullaeva GJ
- Abifadel M
- Acevedo Rivera KJ
- Adamidis P-S
- Aguilar HG
- Aguilar-Salinas CA
- Al-Khateeb A
- Al-Rasadi K
- Al-Sarraf A
- Al-Sayed N
- Alammari D
- Alareedh M
- Alcala HG
- Alfil S
- Alhabib K
- Alieva RB
- Alkhnifsawi M
- Almahmeed W
- Almeida AF
- Alnouri F
- Alonso R
- Alrowaily NL
- Alsahari A
- Alvarado RM
- Alvarez JA
- Alves AC
- Amezcua Martinez JC
- Anagnostis P
- Anastasiou G
- Antonio-Villa NE
- Antza C
- Aouchiche K
- Aparicio BPN
- Arca M
- Arjona Villica~na RD
- Arriaga Cazares HE
- Ashavaid TF
- Ates S
- Attilakos A
- Averna M
- Ayoub C
- Balligand J-L
- Banach M
- Barrera Bustillo MDLR
- Bartkova I
- Batool H
- Battelino T
- Baumgartner-Kaut M
- Bañares V
- Bendary A
- Benn M
- Benso A
- Berteotti M
- Bertolini S
- Bielecka-Dąbrowa A
- Bilhoto C
- Binder C
- Biolo GB
- Bizjan BJ
- Blom D
- Boccara F
- Bogsrud MP
- Bonanni L
- Borghi C
- Borowiec-Wolna J
- Bossi AC
- Bourbon M
- Branchi A
- Brandts JM
- Bruckert E
- Brunham L
- Buganova I
- Buonuomo PS
- Buresova K
- Béliard S
- Calabrò P
- Calandra S
- Capra ME
- Cariou B
- Carrera RA
- Carrié A
- Casula M
- Catapano AL
- Cavallaro R
- Cefalù AB
- Cepova J
- Chacon RC
- Charrières S
- Chlebus I
- Chlebus K
- Chmara M
- Chua Y-A
- Cipollone F
- Citroni N
- Coelho R
- Cohen H
- Cooremans ER
- Corral P
- Correia S
- Cottin Y
- Cruz D
- Cuevas A
- Dalal JJ
- Davletov K
- De Andrés R
- De Gier C
- De los Rios Ibarra MO
- Debeljak M
- Debreova M
- Del Ben M
- Deltas C
- Demeure F
- Descamps OS
- Dharmayat KI
- Di Filippo M
- Dieplinger H
- Do D-L
- Dominguez GJ
- Doumas M
- Dourmap C
- Drogari E
- Durlach V
- Durst R
- Dvorakova J
- Dwiputra B
- Díaz-Díaz JL
- Elbahry A
- Elias-Lopez D
- Encinas BR
- Ezhov MV
- Fabryova L
- Farnier M
- Federici M
- Ferreira P
- Ferreira-Hermosillo A
- Ferri C
- Ferrieres D
- Ferrières J
- Figueroa Andrade MH
- Filippatos T
- Fiorenza AM
- Fortunato G
- Fozilov KG
- Freiberger T
- Fuentes-Jiménez F
- Futema M
- Gach A
- Gaita D
- Galema-Boers A
- Galimberti F
- Gallo A
- Gama G
- Ganokroj P
- Garcia de Leon LE
- Garcia AH
- Garcia AYR
- Garcia P
- Gardu~no Garcia JJ
- Garnica Cuellar JC
- Garoufi A
- Gaudet D
- Gazzotti M
- Genest J
- Georgiou A
- Ghaleb Y
- Gilis-Malinowska N
- Giorgino F
- Gomez Cruz JR
- Gomez Herrera LG
- Gonova K
- Gonzalez Gonzalez JR
- Gonzalez PAC
- Goudev A
- Greber-Platzer S
- Groselj U
- Guardamagna O
- Guerra A
- Guzman BG
- Hankard R
- Harada-Shiba M
- Harangi M
- Hegele RA
- Hellman M
- Hennig M
- Herrera UJ
- Holguin Almada JR
- Holven KB
- Hosseini S
- Hovingh GK
- Humphries SE
- Huong Truong T
- Hyanek J
- Höllerl F
- Iacovides P
- Iannuzzo G
- Innerhofer R
- Ioannou A
- Iughetti L
- Jambart S
- Jamialahmadi T
- Jesina P
- Jóźwiak J
- Kadir SHSA
- Kadurova M
- Kan LE
- Karall D
- Kareem H
- Kasim NAM
- Kayikcioglu M
- Khan SA
- Khoshimov SU
- Khovidhunkit W
- Khudary AA
- Kim N-T
- Kiouri E
- Klabnik A
- Kleinschmidt M
- Kolovou G
- Kolovou V
- Konopka A
- Kostis A
- Kotsis V
- Koumaras C
- Koutagiar I
- Kovac J
- Kozárová M
- Lalic K
- Lalic NM
- Lamari F
- Lambadiari V
- Latif AZA
- Latkovskis G
- Laufs U
- Le H-A
- Le T-T
- Leitersdorf E
- Lemale J
- Lewek J
- Lia S
- Liamis G
- Liberopoulos E
- Lima-Martinez MM
- Lin J
- Lischka J
- Lobarinhas G
- Lopes A
- Lopez HA
- Ludvik B
- Lupi A
- Lyons ARM
- Macias JJC
- Maher V
- Mahfouz L
- Malik M
- Maly J
- Mandraffino G
- Marais AD
- Maroni L
- Martagon AJ
- Masuda D
- Mata P
- Matos LD
- Mawlawi HA
- McCrindle B
- Medeiros AM
- Medrano Rodriguez AB
- Mehta R
- Mendez Valencia CV
- Mertens A
- Michalska-Grzonkowska A
- Milionis H
- Miltiadous G
- Minicocci I
- Mirrakhimov E
- Miserez AR
- Miserez EB
- Mitchenko O
- Mlinaric M
- Moffa S
- Molk N
- Mollaki V
- Mombelli G
- Morales Oyervides JC
- Moulin P
- Moura MD
- Mourre F
- Mouzarou A
- Muntoni S
- Muñiz-Grijalvo O
- Myśliwiec M
- März W
- Mäser M
- Nascimbeni F
- Nawawi H
- Nazli SA
- Nguyen M-N-T
- Nikolov F
- Nizamov UI
- Nociar J
- Nor NSM
- Nordestgaard BG
- Novodvorsky P
- Olmastroni E
- Ortega AF
- Osorio MLR
- Padilla Padilla FG
- Paillard F
- Pais P
- Pajkowski M
- Palma I
- Panayiotou AG
- Paragh G
- Parati G
- Parczewska A
- Passaro A
- Pecchioli V
- Pederiva C
- Pellegatta F
- Peng FK
- Peretti N
- Perez Vazquez DI
- Perica D
- Petakov A
- Petrov I
- Petrulioniene Z
- Pipek M
- Pipolo A
- Pirro M
- Pisciotta L
- Pistkova E
- Podkrajsek KT
- Pojskic B
- Polychronopoulos G
- Ponde CK
- Popovic L
- Portano JDM
- Portilla NC
- Postadzhiyan A
- Potočňáková L
- Pradignac A
- Prado RM
- Proyias P
- Pujia A
- Raal F
- Rabès J-P
- Rajkovic N
- Rallidis L
- Ramaswami U
- Ramirez GAG
- Rana MA
- Ranai NM
- Raslova K
- Rasulic I
- Ray KK
- Razman AZ
- Reda A
- Reddy LL
- Reiner Ž
- Repetti E
- Retana GG
- Reyes Rodriguez EA
- Reyes X
- Reynaud R
- Rhadi SH
- Ribeiro R
- Rinaldi E
- Rizos CV
- Rodriguez EM
- Roeters van Lennep J
- Romanowska-Kocejko M
- Ruel I
- Sadiq F
- Sadoh W
- Sadykova D
- Sahebkar A
- Salgado JM
- Sanin V
- Santos R
- Sarzani R
- Saucedo JR
- Sauque-Reyna L
- Sawhney JPS
- Sbrana F
- Schiele F
- Schmieder R
- Scholl-Bürgi S
- Schreier L
- Schunkert H
- Schurr D
- Scicali R
- Sfikas G
- Shaghee F
- Shah S
- Shah SAV
- Shek AB
- Shipton JL
- Shpitzen S
- Sibaja CM
- Sikonja J
- Silva F
- Simental Mendia LE
- Simoneau I
- Simões F
- Singh S
- Skalidis E
- Skoumas I
- Slastnikova E
- Sobrevilla FL
- Sokal E
- Soran H
- Spenerova M
- Stabouli S
- Starostecka E
- Stephenne X
- Stevens CAT
- Stroes E
- Stróżyk A
- Stylianou A
- Su T-C
- Subramaniam T
- Sultan A
- Suppressa P
- Susekov A
- Sustar U
- Sykora J
- Symeonides P
- S|ulakova A
- Tamayo MT
- Tarugi P
- Tavares M
- Thajer A
- Thushara Matthias A
- Tichy L
- Tilney M
- Tisheva S
- Tomlinson B
- Toplak H
- Torres MTM
- Toukalkova L
- Tounian P
- Trenti C
- Trogkanis E
- Tsaroumi A
- Tselepis AD
- Tybjærg-Hansen A
- Tziomalos K
- Tzvetkov I
- Urbanova Z
- Valdez Talavera LA
- Valero R
- Vallejo-Vaz AJ
- Varga T
- Vargas GC
- Vargas-Vazquez A
- Vasanwala RF
- Venkatesh SA
- Vera Arroyo LE
- Verges B
- Verma IC
- Viigimaa M
- Virtuoso MJ
- Vohnout B
- Vrablik M
- Vázquez Cárdenas A
- Wang L
- Wasąg B
- Watts GF
- Weigman A
- Werba JP
- Wojtecka A
- Yamashita S
- Yelnik C
- Yotov Y
- Zacharis E
- Zakirova DV
- Zambon A
- Zazueta AR
- Zdrojewski T
- Zenti MG
- Zepeda Carrillo EA
- Zubieta VM
- Šaligova J
- Żarczyńska-Buchowiecka M
- Publication venue
- Elsevier
- Publication date
- 29/08/2023
- Field of study
Background Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies. Methods For this cross-sectional study, we assessed children and adolescents younger than 18 years with a clinical or genetic diagnosis of HeFH at the time of entry into the Familial Hypercholesterolaemia Studies Collaboration (FHSC) registry between Oct 1, 2015, and Jan 31, 2021. Data in the registry were collected from 55 regional or national registries in 48 countries. Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13·0 mmol/L were excluded from this study. Data were assessed overall and by WHO region, World Bank country income status, age, diagnostic criteria, and index-case status. The main outcome of this study was to assess current identification and management of children and adolescents with familial hypercholesterolaemia. Findings Of 63 093 individuals in the FHSC registry, 11 848 (18·8%) were children or adolescents younger than 18 years with HeFH and were included in this study; 5756 (50·2%) of 11 476 included individuals were female and 5720 (49·8%) were male. Sex data were missing for 372 (3·1%) of 11 848 individuals. Median age at registry entry was 9·6 years (IQR 5·8–13·2). 10 099 (89·9%) of 11 235 included individuals had a final genetically confirmed diagnosis of familial hypercholesterolaemia and 1136 (10·1%) had a clinical diagnosis. Genetically confirmed diagnosis data or clinical diagnosis data were missing for 613 (5·2%) of 11 848 individuals. Genetic diagnosis was more common in children and adolescents from high-income countries (9427 [92·4%] of 10 202) than in children and adolescents from non-high-income countries (199 [48·0%] of 415). 3414 (31·6%) of 10 804 children or adolescents were index cases. Familial-hypercholesterolaemia-related physical signs, cardiovascular risk factors, and cardiovascular disease were uncommon, but were more common in non-high-income countries. 7557 (72·4%) of 10 428 included children or adolescents were not taking lipid-lowering medication (LLM) and had a median LDL-C of 5·00 mmol/L (IQR 4·05–6·08). Compared with genetic diagnosis, the use of unadapted clinical criteria intended for use in adults and reliant on more extreme phenotypes could result in 50–75% of children and adolescents with familial hypercholesterolaemia not being identified. Interpretation Clinical characteristics observed in adults with familial hypercholesterolaemia are uncommon in children and adolescents with familial hypercholesterolaemia, hence detection in this age group relies on measurement of LDL-C and genetic confirmation. Where genetic testing is unavailable, increased availability and use of LDL-C measurements in the first few years of life could help reduce the current gap between prevalence and detection, enabling increased use of combination LLM to reach recommended LDL-C targets early in life. Funding Pfizer, Amgen, Merck Sharp & Dohme, Sanofi–Aventis, Daiichi Sankyo, and Regeneron
Multi-messenger observations of a binary neutron star merger
- Author
- Aab A
- Aartsen MG
- Abbott BP
- Abbott R
- Abbott TD
- Abbott TMC
- Abdalla H
- Abe F
- Abeysekara AU
- Abramo LR
- Abramowski A
- Abreu P
- Acernese F
- Acero F
- Ackermann M
- Ackley K
- Ackley K
- Adams C
- Adams J
- Adams SM
- Adams T
- Addesso P
- Adhikari RX
- Adya VB
- Affeldt C
- Afrough M
- Agarwal B
- Agathos M
- Agatsuma K
- Aggarwal N
- Aglietta M
- Agliozzo C
- Agudo I
- Aguiar OD
- Aguilar JA
- Aharonian F
- Ahlers M
- Ahrens M
- Aiello L
- Ain A
- Ajith P
- Akras S
- Al Samarai I
- Albert A
- Albert A
- Albuquerque IFM
- Albury JM
- Alcaniz JS
- Alexander KD
- Alfaro R
- Alighieri S Di Serego
- Allam S
- Allekotte I
- Allen B
- Allen G
- Allison J
- Allison JR
- Allocca A
- Almela A
- Altin PA
- Altmann D
- Alvarez C
- Alvarez JD
- Alvarez M Dovale
- Alvarez-Muiz J
- Amati L
- Amato A
- An T
- Ananyeva A
- Anastasi GA
- Anchordoqui L
- Andeen K
- Anderson JP
- Anderson SB
- Anderson T
- Anderson WG
- Andrada B
- Andre M
- Andreoni I
- Andreoni I
- Andringa S
- Angelova SV
- Anghinolfi M
- Angner EO
- Angus CR
- Annis J
- Ansseau I
- Antier S
- Anton G
- Antonelli LA
- Antonelli LA
- Anupama GC
- Aoki K
- Aoki W
- Appert S
- Aptekar RL
- Arai K
- Arakawa M
- Aramo C
- Araya MC
- Arcavi I
- Arceo R
- Ardid M
- Areeda JS
- Aresu G
- Argan A
- Argelles C
- Arnaud N
- Array LWA Long Wavelength
- Array MWA Murchison Widefield
- Arrieta M
- Arsene N
- Arteaga-Velzquez JC
- Artola R
- Arun KG
- Asakura Y
- Asaoka Y
- Ascenzi S
- Ashall C
- Ashley MCB
- Ashton G
- Asorey H
- Assis P
- Ast M
- Aston SM
- Astone P
- Atallah DV
- ATLAS
- Atwood WB
- Aubert J-J
- Aubert P
- Aublin J
- Auffenberg J
- Aufmuth P
- Aulbert C
- AultONeal K
- Austin C
- Avgitas T
- Avila G
- Avila-Alvarez A
- Awad A Kuotb
- Axani S
- Baar S
- Babak S
- Bachetti M
- Backes M
- Bacon P
- Bader MKM
- Badescu AM
- Bae S
- Bagherpour H
- Bai X
- Bailes M
- Baker PT
- Balaceanu A
- Balanutsa PV
- Balasubramanian A
- Balbinot E
- Baldaccini F
- Baldini L
- Ballardin G
- Ballmer SW
- Bally J
- Balzer A
- Banagiri S
- Banerji M
- Bannister KW
- Barayoga JC
- Barbarino C
- Barbato F
- Barber AS
- Barbiellini G
- Barbiellini G
- Barclay SE
- Baret B
- Barish BC
- Barker D
- Barkett K
- Barnard M
- Barnes J
- Barone F
- Barr B
- Barrios-Marti J
- Barron JP
- Barsotti L
- Barsuglia M
- Barta D
- Barthelmy SD
- Bartlett J
- Bartos I
- Barway S
- Barway S
- Barwick SW
- Basa S
- Bassiri R
- Basti A
- Bastieri D
- Batch JC
- Bauer FE
- Bauer FE
- Baum V
- Bawaj M
- Bay R
- Bayley JC
- Bazzan M
- Bazzano A
- Bchele M
- Beardmore AP
- Beardsley A
- Beatty JJ
- Becerril A
- Becherini Y
- Bechtol K
- Becker KH
- Becsy B
- Beer C
- Bejger M
- Belahcene I
- Belhorma B
- Bell AS
- Bellazzini R
- Bellido JA
- Bellm E
- Belmont-Moreno E
- Benetti S
- Benkhali F Ait
- Benoit-Levy A
- BenZvi SY
- Berat C
- Berenji B
- Berge D
- Berger BK
- Berger E
- Bergmann G
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- Fernandez-Galiana A
- Feroci M
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- Fulda P
- Funk S
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- Furusawa H
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- Fusco LA
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- Goldstein A
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- Golup G
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- Guelbenzu A Nicuesa
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- Guo CC
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- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
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- AKI Research Group
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- Casals XN
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- Castellanos A
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- Chen YS
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- Cheng KC
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- Chernyshuk S
- Chevret S
- Chhor V
- Chiang CC
- Chiang CH
- Chiang CH
- Chiang CH
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- Chiou KR
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- Chiu LC
- Chiumello D
- Chiurazzi C
- Chiurazzi C
- Cho Y
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- Chou W
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- Chouvarda I
- Christopher KB
- Chrétien JM
- Chrétien JM
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- Combes A
- Concha P
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- Constan A
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- Conti G
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- Corona A
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- Corte FD
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- Corzo L
- Coss-Bu JA
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- Costanzo E
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- Curiel-Balsera E
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- Cutuli SL
- Câmara M
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- da Silva VZ
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- Dalhuisen A
- Dalorzo M
- Damas P
- Dambrosio M
- Damås JK
- Das Neves A
- David H
- Davis C
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- Day A
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- De Backer A
- De Brito-Ashurst I
- De Cassai A
- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
- De La Rica AS
- De la Torre MA
- De Maglie M
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- De Pascale G
- De Rosa S
- De Sanctis F
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- De Sousa I
- de Vera AP
- de Wilde W
- De Zani D
- Deblier I
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- Del Arco A
- Del Moral OL
- Del Olmo R
- Del Rosario CG
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- Delgado MJ
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- Di Gravio V
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- Elbers PW
- Elgendy M
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- Emmanuel J
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- Endacott R
- Engelberts D
- ENVIN-HELICS Study Group
- Erb J
- Erdogan M
- Eroles AA
- Escalada SH
- Escalada SH
- Escoval A
- Escribá A
- Escórcio S
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- Espinasse F
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- Ferri F
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- Ferrón FR
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- Filipe E
- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
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- Fontana V
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- FROG ICU Investigators
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- GETGAG Working Group
- GETGAG/SEMICYUC
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- González-Jiménez AI
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- Hung WT
- Hung WT
- Hung WT
- Hung WT
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- Ignacio ML
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- Ince C
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- IPREA Study Group
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- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
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- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
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- Jensen JU
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- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
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- Juanas CA
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- Juez A
- Juliarena A
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- Kaminsky GE
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- Kim HJ
- Kim JM
- Kim JM
- Kim JW
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- Ko SB
- Kobayashi A
- Koco E
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- Kodate A
- Kodate A
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- Kolnikova I
- Komuro T
- Kondili E
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- Kooner G
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- Kosuk ME
- Kotsopoulos A
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- Kouatchet A
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- Kox M
- Kraegpoeth A
- Krenn CG
- Krishna B
- Kristof J
- Kruger A
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- Krüger A
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- Ku NS
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- Kubota K
- Kuebler WM
- Kulaga EV
- Kulkarni AP
- Kumari BK
- Kumbamu A
- Kunze-Szikszay N
- Kurmukov IA
- Kurth T
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- Kwon HM
- Kwon WY
- Kwon WY
- Kwon WY
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- Kyle UG
- Kyle UG
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- Labra C
- Lacerda P
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- Lafuente E
- Lagonidis D
- Lagos R
- Lahmer T
- Lai CC
- Lai CH
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- Lapteva K
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- Latini R
- Latini R
- Latini R
- Latorre J
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- Lavrentieva A
- Lawrence N
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- Lee WY
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- Leitao AL
- Leite RT
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- Liao X
- Lichtenstein D
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- Limuti R
- Lin KC
- Lin KC
- Lin KC
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- Lin KL
- Lin PH
- Lin SC
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- Lin WC
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- Lischinsky A
- Lissonde F
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- Liu CP
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- Llorente B
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- Lobo-Civico A
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- Lombardo MD
- Londoño JG
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- Loudet CI
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- MacPhee I
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- Madueño VP
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- Maertens B
- Maggiorini M
- Maghsoudi B
- Magnanimi E
- Magnoni S
- Magret M
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- Maistry N
- Maitra S
- Makiko S
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- Marcos-Zambrano LJ
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- Marin-Mateos H
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- Martín-Loeches I
- Martín-Loeches I
- Martínez F
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- Martínez MV
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- Martínez-Carmona JF
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- Mazurenko G
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- Mejías CR
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- Melnyk L
- Melo N
- Mendes A
- Mendez MC
- Mendonca AV
- Mendsaikhan N
- Menendez R
- Mengelle C
- Mercat A
- Mercat A
- Mercat A
- Mergulhão PJ
- Merino-Vega D
- Messenger D
- Mezidi M
- Mezidi M
- Michel L
- Midwinter MJ
- Mignot T
- Miguelena PR
- Mihara Y
- Millar M
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- Mimoz O
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- Mizugaki A
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- Mora-Ordóñez JM
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- Okamoto H
- Okayama Research Investigation Organizing Network (ORION)investigators
- Olaechea P
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- Olivares F
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- Oobayashi W
- Orden VA
- Ori C
- Orlando A
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- Philips BJ
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- Picoita F
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- Radu V
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- Rodríguez FG
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- Romeu JD
- Rood PJ
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- Rossini P
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- Suchomel P
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- Tofiño AL
- Toh CH
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- Tomas E
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- WIND study group
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- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
- Zahorec M
- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
- Zeroual N
- Zerva L
- Zhang J
- Zhou JC
- Zhou JC
- Zhou JX
- Zhovnir V
- Zibandah N
- Zijlstra F
- Zimmerman J
- Zogheib E
- Zogheib E
- Zogheib E
- Zullino V
- Zwaag J
- Zýková I
- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Search for High-Mass Resonances Decaying to τν in pp Collisions at √s=13 TeV with the ATLAS Detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Adachi S
- Adamczyk L
- Adelman J
- Adersberger M
- Adye T
- Affolder AA
- Afik Y
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahlen SP
- Ahmadov F
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov AV
- Alberghi GL
- Albert J
- Albicocco P
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alstaty MI
- Alvarez Gonzalez B
- Alvarez Piqueras D
- Alviggi MG
- Amadio BT
- Amaral Coutinho Y
- Ambroz L
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
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- Anders JK
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- Andreazza A
- Andrei V
- Angelidakis S
- Angelozzi I
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antonelli M
- Antrim DJ
- Anulli F
- Aoki M
- Arabidze G
- Arai Y
- Araque JP
- Araujo Ferraz V
- Araujo Pereira R
- Araya S Tapia
- Arce ATH
- Ardell RE
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Armadans R Caminal
- Armbruster AJ
- Armitage LJ
- Arnaez O
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- Artamonov A
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- Artz S
- Asai S
- Asbah N
- Ashkenazi A
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- Astigarraga ME Pozo
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- Baines JT
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- Brock I
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- Budagov IA
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- Burmeister I
- Burr JTP
- Buschmann E
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- Buttar CM
- Butterworth JM
- Butti P
- Buttinger W
- Buzatu A
- Buzykaev AR
- Bylund O Bessidskaia
- Cabras G
- Cabrera Urban S
- Caforio D
- Cai H
- Cairo VMM
- Cakir I Turk
- Cakir O
- Calace N
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
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- Calvet D
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- Campoverde A
- Canale V
- Cantero J
- Cao T
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- Caprini I
- Caprini M
- Capua M
- Carbone RM
- Cardarelli R
- Cardillo F
- Carli I
- Carli T
- Carlino G
- Carlson BT
- Carminati L
- Carney RMD
- Caron S
- Carquin E
- Carra S
- Carrillo-Montoya GD
- Casadei D
- Casado MP
- Casha AF
- Casolino M
- Casper DW
- Castelijn R
- Castillo Gimenez V
- Castillo LR Flores
- Castro NF
- Catinaccio A
- Catmore JR
- Cattai A
- Caudron J
- Cavaliere V
- Cavallaro E
- Cavalli D
- Cavalli-Sforza M
- Cavasinni V
- Celebi E
- Ceradini F
- Cerda Alberich L
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cervelli A
- Cetin SA
- Chafaq A
- Chakraborty D
- Chan SK
- Chan WS
- Chan YL
- Chang P
- Chapman JD
- Charlton DG
- Chau CC
- Chavez Barajas CA
- Che S
- Chegwidden A
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chelstowska MA
- Chen C
- Chen C
- Chen H
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- Chen Y-H
- Cheng HC
- Cheng HJ
- Cheplakov A
- Cheremushkina E
- Cheu E
- Cheung K
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm AS
- Chitan A
- Chiu I
- Chiu YH
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- Chomont AR
- Chouridou S
- Chow YS
- Christodoulou V
- Chu MC
- Chudoba J
- Chuinard AJ
- Chwastowski JJ
- Chytka L
- Cinca D
- Cindro V
- Cioara IA
- Ciocio A
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- Citron ZH
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- Collaboration ATLAS
- Collot J
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- Coniavitis E
- Connell SH
- Connelly IA
- Constantinescu S
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- Corga K De Vasconcelos
- Cormier F
- Cormier KJR
- Cornell S Diez
- Corradi M
- Correia AM Henriques
- Corrigan EE
- Corriveau F
- Cortes-Gonzalez A
- Costa MJ
- Costanzo D
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- Cox BE
- Crane J
- Cranmer K
- Crawley SJ
- Creager RA
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- Crescioli F
- Cristinziani M
- Croft V
- Crosetti G
- Cueto A
- Cukierman AR
- Curatolo M
- Cuth J
- Czekierda S
- Czodrowski P
- D'amen G
- D'Auria S
- D'eramo L
- D'Onofrio M
- Da Cunha Sargedas De Sousa MJ
- Da Via C
- Dabrowski W
- Dado T
- Dahbi S
- Dai T
- Dale O
- Dallaire F
- Dallapiccola C
- Dam M
- Damazio D Oliveira
- Dandoy JR
- Daneri MF
- Dang NP
- Dann NS
- Danninger M
- Dao V
- Darbo G
- Darmora S
- Dartsi O
- Dattagupta A
- Daubney T
- Davey W
- David C
- Davidek T
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- Dawson I
- de Asmundis R
- De Benedetti A
- De Bruin PH Sales
- De Castro S
- De Cecco S
- De Groot N
- de Jong P
- De la Torre H
- de Lima DE Ferreira
- De Lorenzi F
- De Maria A
- De Pedis D
- De Regie JB De Vivie
- de Renstrom PA Bruckman
- De Salvo A
- De Sanctis U
- De Santo A
- De K
- Debenedetti C
- Dedovich DV
- Dehghanian N
- Del Gaudio M
- Del Peso J
- Delgove D
- Deliot F
- Delitzsch CM
- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- della Volpe D
- Delmastro M
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- Delsart PA
- DeMarco DA
- Demers S
- Demichev M
- Denisov SP
- Denysiuk D
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- Derkaoui JE
- Derue F
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- Deviveiros PO
- Dewhurst A
- Dhaliwal S
- Di Bello FA
- Di Ciaccio A
- Di Ciaccio L
- Di Clemente WK
- Di Donato C
- Di Girolamo A
- Di Micco B
- Di Nardo R
- Di Petrillo KF
- Di Simone A
- Di Sipio R
- Di Valentino D
- Diaconu C
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- Dias do Vale T
- Dias FA
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- Dickinson J
- Diehl EB
- Dietrich J
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- do Vale MAB
- Dobre M
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- Doglioni C
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- Drechsler E
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- Duehrssen M
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- Zivkovic L
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- Zorbas TG
- Zou R
- Zu Theenhausen H Meyer
- zur Nedden M
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2018
- Field of study
A search for high-mass resonances decaying to τν using proton-proton collisions at √s=13 TeV produced by the Large Hadron Collider is presented. Only τ-lepton decays with hadrons in the final state are considered. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 36.1 fb−1. No statistically significant excess above the standard model expectation is observed; model-independent upper limits are set on the visible τν production cross section. Heavy W′ bosons with masses less than 3.7 TeV in the sequential standard model and masses less than 2.2–3.8 TeV depending on the coupling in the nonuniversal G(221) model are excluded at the 95% credibility level
Combined measurement of differential and total cross sections in the H → γγ and the H → ZZ* → 4ℓ decay channels at s=13 TeV with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abhayasinghe DK
- Abidi SH
- Abouzeid OS
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- Yao W-M
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- Yildirim E
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- Yusuff I
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- Zaffaroni E
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- Zaitsev AM
- Zakharchuk N
- Zalieckas J
- Zambito S
- Zanzi D
- Zaripovas DR
- Zeitnitz C
- Zeißner SV
- Zemaityte G
- Zeng JC
- Zeng Q
- Zenin O
- Zerwas D
- Zgubič M
- Zhang D
- Zhang DF
- Zhang F
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang L
- Zhang M
- Zhang P
- Zhang R
- Zhang R
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao X
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zhou B
- Zhou C
- Zhou L
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Zinser M
- Ziolkowski M
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zur Nedden M
- Zwalinski L
- Álvarez Piqueras D
- Åkesson TPA
- Šfiligoj T
- Ženiš T
- Živković L
- Publication venue
- Elsevier
- Publication date
- 01/01/2018
- Field of study
A combined measurement of differential and inclusive total cross sections of Higgs boson production is performed using 36.1 fb−1 of 13 TeV proton–proton collision data produced by the LHC and recorded by the ATLAS detector in 2015 and 2016. Cross sections are obtained from measured H→γγ and H→ZZ*(→4ℓ event yields, which are combined taking into account detector efficiencies, resolution, acceptances and branching fractions. The total Higgs boson production cross section is measured to be 57.0−5.9 +6.0 (stat.) −3.3 +4.0 (syst.) pb, in agreement with the Standard Model prediction. Differential cross-section measurements are presented for the Higgs boson transverse momentum distribution, Higgs boson rapidity, number of jets produced together with the Higgs boson, and the transverse momentum of the leading jet. The results from the two decay channels are found to be compatible, and their combination agrees with the Standard Model predictions
Operation and performance of the ATLAS Tile Calorimeter in Run 1
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Abeloos B
- Abhayasinghe DK
- Abidi SH
- Abouelfadl 
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Adachi S
- Adamczyk L
- Adelman J
- Adersberger M
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Aielli G
- Akatsuka S
- Akerstedt H
- Akilli E
- Akimov AV
- Alberghi GL
- Albert J
- Albicocco P
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alstaty MI
- Alvarez 
- Alviggi MG
- Amadio BT
- Amaral Coutinho Y
- Ambroz L
- Amelung C
- Amidei D
- Amor 
- Amoroso S
- Amrouche CS
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Anderson KJ
- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angelozzi I
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
- Aperio Bella L
- Arabidze G
- Arai Y
- Araque JP
- Araujo Ferraz V
- Arce ATH
- Ardell RE
- Arduh FA
- Argos FC
- Arguin J-
- Argyropoulos S
- Armadans R
- Armbruster AJ
- Armitage LJ
- Armstrong A
- Arnaez O
- Arnold H
- Arratia M
- Arslan O
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Ashkenazi A
- Asimakopoulou EM
- Asquith L
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- Kivernyk O
- Kladiva E
- Klapdor-Kleingrothaus T
- Klein M
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- Klein U
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- Klimentov A
- Klingenberg R
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- Klioutchnikova T
- Klitzner FF
- Kluit P
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- Knoops EBFG
- Knue A
- Kobayashi A
- Kobayashi D
- Kobayashi T
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- Kocian M
- Kodys P
- Koffas T
- Koffeman E
- Koi T
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- Koletsou I
- Kondo T
- Kondrashova N
- Kono T
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- Konstantinides V
- Konstantinidis N
- Konya B
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- Koperny S
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- Korcyl K
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- Korn A
- Korolkov I
- Korolkova EV
- Kortner O
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- Kosek T
- Kostyukhin VV
- Kotwal A
- Koulouris A
- Kourkoumeli-Charalampidi A
- Kourkoumelis C
- Kourlitis E
- Kouskoura V
- Kowalewska AB
- Kowalewski R
- Kowalski TZ
- Kozakai C
- Kozanecki W
- Kozhin AS
- Köhler NM
- Köneke K
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- Kramberger G
- Krasnopevtsev D
- Krasny MW
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- Kuechler JT
- Kuehn S
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- Kukhtin V
- Kukla R
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- Kuleshov S
- Kulinich YP
- Kuna M
- Kunigo T
- Kupco A
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- Kurochkin YA
- Kurth MG
- Kuwertz ES
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- Landon MPJ
- Lanfermann MC
- Lang VS
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- Laplace S
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- Lasagni Manghi F
- Lassnig M
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- Law AT
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- Le B
- LeBlanc M
- LeCompte T
- Ledroit-Guillon F
- Lee CA
- Lee GR
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- Leggett C
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- Leight WA
- Leisos A
- Leite MAL
- Leitner R
- Lellouch D
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- Leney KJC
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- Liberti B
- Liblong A
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- Limosani A
- Lin CY
- Lin K
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- Linck RA
- Lindquist BE
- Lionti AL
- Lipeles E
- Lipniacka A
- Lisovyi M
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- Lopez 
- Lopez JA
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- Zur 
- Zwalinski L
- Ženiš T
- Živković L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
The Tile Calorimeter is the hadron calorimeter covering the central region of the ATLAS experiment at the Large Hadron Collider. Approximately 10,000 photomultipliers collect light from scintillating tiles acting as the active material sandwiched between slabs of steel absorber. This paper gives an overview of the calorimeter’s performance during the years 2008–2012 using cosmic-ray muon events and proton–proton collision data at centre-of-mass energies of 7 and 8TeV with a total integrated luminosity of nearly 30 fb−1. The signal reconstruction methods, calibration systems as well as the detector operation status are presented. The energy and time calibration methods performed excellently, resulting in good stability of the calorimeter response under varying conditions during the LHC Run 1. Finally, the Tile Calorimeter response to isolated muons and hadrons as well as to jets from proton–proton collisions is presented. The results demonstrate excellent performance in accord with specifications mentioned in the Technical Design Report
Performance of missing transverse momentum reconstruction with the ATLAS detector using proton–proton collisions at √s = 13 TeV
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
The performance of the missing transverse momentum (EmissT) reconstruction with the ATLAS detector is evaluated using data collected in proton–proton collisions at the LHC at a centre-of-mass energy of 13 TeV in 2015. To reconstruct EmissT, fully calibrated electrons, muons, photons, hadronically decaying τ -leptons, and jets reconstructed from calorimeter energy deposits and charged-particle tracks are used. These are combined with the soft hadronic activity measured by reconstructed charged-particle tracks not associated with the hard objects. Possible double counting of contributions from reconstructed charged-particle tracks from the inner detector, energy deposits in the calorimeter, and reconstructed muons from the muon spectrometer is avoided by applying a signal ambiguity resolution procedure which rejects already used signals when combining the various EmissT contributions. The individual terms as well as the overall reconstructed EmissT are evaluated with various performance metrics for scale (linearity), resolution, and sensitivity to the data-taking conditions. The method developed to determine the systematic uncertainties of the EmissT scale and resolution is discussed. Results are shown based on the full 2015 data sample corresponding to an integrated luminosity of 3.2 fb−1
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