Macros in sbt: Problem Solved!

In the previous report, we described how incremental compilation was made more complicated when macro-enabled programs are involved, and we implemented the foundations of the support for metaprograms in sbt, a build tool and incremental compiler for Scala. Since then, we worked on improving the internal representation of dependency relationships between files in sbt, to make it easier to extend sbt and to define new relationships. This crucial development allowed us to fix all the remaining problems that sbt had with macros: how should we handle their transitive dependencies? How can we know what they inspect during their expansion? Are there other means by which macros could introduce dependencies? How should we use these informations? In this report, we will expose the new techniques that have been proposed and implemented to offer a complete support for metaprograms along with all their dependencies in sbt, and explain the most relevant parts of their implementation

Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

International audienceThe aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality. Our study included all patients on dialysis recorded in the French REIN Registry in April 2020. Clinical characteristics at last follow-up and the evolution of COVID-19 illness severity over time were recorded for diagnosed cases (either suspicious clinical symptoms, characteristic signs on the chest scan or a positive reverse transcription polymerase chain reaction) for SARS-CoV-2. A total of 1,621 infected patients were reported on the REIN registry from March 16th, 2020 to May 4th, 2020. Of these, 344 died. The prevalence of COVID-19 patients varied from less than 1% to 10% between regions. The probability of being a case was higher in males, patients with diabetes, those in need of assistance for transfer or treated at a self-care unit. Dialysis at home was associated with a lower probability of being infected as was being a smoker, a former smoker, having an active malignancy, or peripheral vascular disease. Mortality in diagnosed cases (21%) was associated with the same causes as in the general population. Higher age, hypoalbuminemia and the presence of an ischemic heart disease were statistically independently associated with a higher risk of death. Being treated at a selfcare unit was associated with a lower risk. Thus, our study showed a relatively low frequency of COVID-19 among dialysis patients contrary to what might have been assumed