10 research outputs found

    Producto alimenticio en forma de salsa tipo mayonesa y procedimiento de preparación

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    Producto alimenticio en forma de salsa tipo mayonesa y procedimiento de preparación. Salsa tipo mayonesa en cuya composición se incluye como emulsionante exclusivamente suero de mantequilla. Los restantes componentes son los habitualmente utilizados en este tipo de productos, como aceite vegetal, agua, vinagre de vino, azúcar, sal, zumo de limón, conservante y, opcionalmente, colorante y estabilizante. El procedimiento de preparación del producto se lleva a cabo en un equipo mezclador rotatorio siguiendo un orden determinado de adición de dichos componentes. El producto obtenido es estable al menos 16 meses a temperatura ambiente o mantenido en frío a 4◦C.Españ

    Large expert-curated database for benchmarking document similarity detection in biomedical literature search

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    Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

    Producto alimenticio en forma de salsa tipo mayonesa y procedimiento de preparación

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    Solicitud de patente (concesión en curso).-- Referencia OEPM: P200600466.-- Fecha de presentación: 22/02/2006.-- Solicitantes: Universidad de Sevilla (US), Corporación Alimentaria Peñasanta, S.A., Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Huelva.Salsa tipo mayonesa en cuya composición se incluye como emulsionante exclusivamente suero de mantequilla. Los restantes componentes son los habitualmente utilizados en este tipo de productos, como aceite vegetal, agua, vinagre de vino, azúcar, sal, zumo de limón, conservante y, opcionalmente, colorante y estabilizante. El procedimiento de preparación del producto se lleva a cabo en un equipo mezclador rotatorio siguiendo un orden determinado de adición de dichos componentes. El producto obtenido es estable al menos 16 meses a temperatura ambiente o mantenido en frío a 4°C.Peer reviewe

    Evaluación por competencias de la dimensión ética en la formación de Psicólogos en Colombia

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    14 páginasThis article presents the results of an inter-institutional research project between Universidad de La Sabana and Universidad Santo Tomás. An instrument was constructed to evaluate the level of development of five ethical competencies; and, from a non-random sample of 100 students from five psychology faculties in Bogota, first year and last year students were compared. The instrument was found to have 95% reliability and 69.51% factorial validity. It was also concluded that 80% of the students evaluated are at a level of development between deficient and acceptable of the competencies, and 20% are at a level of satisfactory development of these competencies; the final year students fall within this range. Translated with www.DeepL.com/Translator (free version)Este artículo presenta los resultados de una investi- gación interinstitucional Universidad de La Sabana — Universidad Santo Tomás. Se construyó un instrumen- to para evaluar el nivel de desarrollo de cinco com- petencias éticas; y, a partir de una muestra, no aleatoria, de 100 estudiantes de cinco facultades de psicología de Bogotá, se compararon estudiantes de primer año y de último año. Se encontró en el instru- mento diseñado un 95% de confiabilidad, y un 69.51% de validez factorial. Igualmente, se concluyó que el 80% de los estudiantes evaluados se encuentra en un nivel de desarrollo entre deficiente y aceptable de las competencias, y el 20% se encuentra en un nivel de desarrollo satisfactorio de dichas competencias; en este rango se inscriben los estudiantes de último año

    Evaluación por competencias de la dimensión ética en la formación de Psicólogos en Colombia

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    International audienceAfter listing all the dream sequences, long or short, found in a 1620s novel, Chan zhen yishi禪真逸史, and showing which rhetorical tools its author uses to open and close these literary dreams, the paper focuses on the study of three dreams that play an important part in the narrative’s structure. Though these dreams were initially interpreted by other protagonists according to the oneiromantic knowledge of the time, it is the elements that these initial readings overlooked that would have a greater effect on the later developments of the tale. Without contesting the value of the divinatory knowledge of dreams, the novelist thus proves himself capable of undertaking original explorations, religious and psychological, in the world of late imperial Chinese dreams.Après avoir recensé tous les épisodes oniriques qui ponctuent le récit de Chan zhen yishi 禪真逸史 (années 1620) et montré par quels procédés rhétoriques son auteur insère les rêves dans le roman, l’article s’attache à l’analyse de trois songes qui jouent un rôle particulièrement important dans sa structure narrative. Si ces rêves sont d’abord interprétés par les protagonistes en fonction du savoir mantique de l’époque, ce sont des éléments non immédiatement décryptables par celui-ci qui auront les plus importantes conséquences sur la structure du récit tout entier. Sans renier la vulgate oniromantique de son temps, l’auteur du roman se montre capable de dépasser celle-ci pour ouvrir l’espace onirique à des explorations religieuses et psychologiques inédites.本文首先歸納了《禪真逸史》(1620年代)中穿插的各種夢境,分析了該書作者將夢境嵌入小說的修辭手段,而後研究了在全書敘述結構中發揮重要作用的三個夢。書中角色根據當時的占夢之學對這些夢作了解讀,但是一些無法當下立解的要素實際上對於全書的敘事至為關鍵。該書作者無意否定占夢的價值,但從宗教和心理兩個方面為帝國晚期的夢寐敘事開創了新的空間

    DIII-D research advancing the physics basis for optimizing the tokamak approach to fusion energy

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    Funding Information: This material is based upon work supported by the US Department of Energy, Office of Science, Office of Fusion Energy Sciences, using the DIII-D National Fusion Facility, a DOE Office of Science user facility, under Awards DE-FC02-04ER54698 and DE-AC52-07NA27344. Publisher Copyright: © 2022 IAEA, Vienna.DIII-D physics research addresses critical challenges for the operation of ITER and the next generation of fusion energy devices. This is done through a focus on innovations to provide solutions for high performance long pulse operation, coupled with fundamental plasma physics understanding and model validation, to drive scenario development by integrating high performance core and boundary plasmas. Substantial increases in off-axis current drive efficiency from an innovative top launch system for EC power, and in pressure broadening for Alfven eigenmode control from a co-/counter-I p steerable off-axis neutral beam, all improve the prospects for optimization of future long pulse/steady state high performance tokamak operation. Fundamental studies into the modes that drive the evolution of the pedestal pressure profile and electron vs ion heat flux validate predictive models of pedestal recovery after ELMs. Understanding the physics mechanisms of ELM control and density pumpout by 3D magnetic perturbation fields leads to confident predictions for ITER and future devices. Validated modeling of high-Z shattered pellet injection for disruption mitigation, runaway electron dissipation, and techniques for disruption prediction and avoidance including machine learning, give confidence in handling disruptivity for future devices. For the non-nuclear phase of ITER, two actuators are identified to lower the L-H threshold power in hydrogen plasmas. With this physics understanding and suite of capabilities, a high poloidal beta optimized-core scenario with an internal transport barrier that projects nearly to Q = 10 in ITER at ∼8 MA was coupled to a detached divertor, and a near super H-mode optimized-pedestal scenario with co-I p beam injection was coupled to a radiative divertor. The hybrid core scenario was achieved directly, without the need for anomalous current diffusion, using off-axis current drive actuators. Also, a controller to assess proximity to stability limits and regulate β N in the ITER baseline scenario, based on plasma response to probing 3D fields, was demonstrated. Finally, innovative tokamak operation using a negative triangularity shape showed many attractive features for future pilot plant operation.Peer reviewe

    Large expert-curated database for benchmarking document similarity detection in biomedical literature search

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    Large expert-curated database for benchmarking document similarity detection in biomedical literature search

    No full text
    Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science. © The Author(s) 2019. Published by Oxford University Press

    Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

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    © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
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