963 research outputs found
The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Clearance of invading microbes requires phagocytes of the innate immune system. However, successful pathogens have evolved sophisticated strategies to evade immune killing. The opportunistic human fungal pathogen Candida albicans is efficiently phagocytosed by macrophages, but causes inflammasome activation, host cytolysis, and escapes after hypha formation. Previous studies suggest that macrophage lysis by C. albicans results from early inflammasome-dependent cell death (pyroptosis), late damage due to glucose depletion and membrane piercing by growing hyphae. Here we show that Candidalysin, a cytolytic peptide toxin encoded by the hypha-associated gene ECE1, is both a central trigger for NLRP3 inflammasome-dependent caspase-1 activation via potassium efflux and a key driver of inflammasome-independent cytolysis of macrophages and dendritic cells upon infection with C. albicans. This suggests that Candidalysin-induced cell damage is a third mechanism of C. albicans-mediated mononuclear phagocyte cell death in addition to damage caused by pyroptosis and the growth of glucose-consuming hyphae
Hundreds of variants clustered in genomic loci and biological pathways affect human height
- Author
- A Johansson
- A Superti-Furga
- Aila Rissanen
- Aki S. Havulinna
- Alan F. Wright
- Alan R. Sanders
- Alan R. Shuldiner
- Albert Hofman
- Albert Vernon Smith
- Alessandro De Grandi
- Alex N. Parker
- Alice M. Arnold
- Alistair S. Hall
- Ana Marusic
- Anders Hamsten
- Andrea Maschio
- Andreas Ziegler
- Andres Metspalu
- Andrew A. Hicks
- Andrew C. Heath
- Andrew P. Morris
- Andrew R. Wood
- Andrew T. Hattersley
- André G. Uitterlinden
- Anke Tönjes
- Anna Dominiczak
- Anna L. Dixon
- Anna-Liisa Hartikainen
- Anne U. Jackson
- Anneli Pouta
- Anthony J. Balmforth
- Antonella Mulas
- Antti Jula
- Arthur W. Musk
- Astrid Petersmann
- AV Segrè
- Ayellet V. Segrè
- B Devlin
- Barbara McKnight
- Ben Oostra
- Benjamin F. Voight
- Brenda W. Penninx
- Cameron Palmer
- Carlo Rivolta
- Carlos Iribarren
- Caroline Hayward
- Caroline S. Fox
- Carsten Oliver Schmidt
- CD Campbell
- Cecilia M. Lindgren
- Charles C. White
- Christian Gieger
- Christian Hengstenberg
- Christopher J. O’Donnell
- Claes Ohlsson
- Constance Chen
- Cornelia M. van Duijn
- Cristen J. Willer
- Dale R. Nyholt
- Daniel Gudbjartsson
- Daniel I. Chasman
- Daniele Cusi
- David J. Hunter
- David P. Strachan
- David S. Siscovick
- David Schlessinger
- Dawn Waterworth
- DB Goldstein
- Devin Absher
- DF Gudbjartsson
- Dominique J. Verlaan
- Dorret I. Boomsma
- Douglas F. Levinson
- Eco J. C. Geus
- Eero Kajantie
- Eleanor Wheeler
- Elin Grundberg
- Elisabeth Widen
- Elizabeth K. Speliotes
- Elizabeth L. Altmaier
- EM Kofoed
- ER Neptune
- Eric Boerwinkle
- Eric E. Schadt
- Erik Ingelsson
- Erika Salvi
- Eva Albrecht
- F Galton
- Fernando Rivadeneira
- Florian Ernst
- Francis S. Collins
- Frank B. Hu
- Fredrik Wiklund
- G Lettre
- G. Bragi Walters
- G. Mark Lathrop
- Gabrielle Boucher
- Gert-Jan van Ommen
- Gonneke Willemsen
- Gonçalo R. Abecasis
- Grant W. Montgomery
- Gudmar Thorleifsson
- Gudny Eiriksdottir
- Guillaume Lettre
- Guillaume Paré
- H.-Erich Wichmann
- Hana Lango Allen
- Harry Campbell
- Heather M. Stringham
- Heikki V. Huikuri
- Helene Alavere
- Henrik Grönberg
- Henry Völzke
- Heribert Schunkert
- Hugh Watkins
- Ida Surakka
- Igor Rudan
- Inga Prokopenko
- Ingrid B. Borecki
- Inke R. König
- Inês Barroso
- Irene Pichler
- Iris M. Heid
- Ivana Kolcic
- J Yang
- Jaakko Kaprio
- Jaakko Tuomilehto
- Jaana Laitinen
- Jacques S. Beckmann
- James F. Wilson
- Jan H. Smit
- Jeanette Erdmann
- Jeffrey R. O’Connell
- Jennie Hui
- Jennifer G. Sambrook
- Jerome I. Rotter
- JH Park
- Jian Yang
- Jianfeng Xu
- Jianjun Liu
- Jianxin Shi
- Jian’an Luan
- Jing Hua Zhao
- Joel N. Hirschhorn
- Johan G. Eriksson
- Johannes Kettunen
- John D. Rioux
- John F. Peden
- John P. Beilby
- John R. B. Perry
- John R. Thompson
- Jonathan P. Tyrer
- Jorma Viikari
- Joshua C. Randall
- Joshua W. Knowles
- Jouke-Jan Hottenga
- Joyce B. J. van Meurs
- Ju-Hyun Park
- Jubao Duan
- Juha Sinisalo
- Julius Suh Ngwa
- K Estrada
- KA Frazer
- Karen L. Mohlke
- Kari E. North
- Kari Stefansson
- Karol Estrada
- Katja K. Aben
- Ke Hao
- Ken Sin Lo
- Keri L. Monda
- Kevin B. Jacobs
- Kirsi H. Pietiläinen
- Kristin G. Ardlie
- L. Adrienne Cupples
- LA Hindorff
- Lachlan Coin
- Lambertus Kiemeney
- Larry D. Atwood
- Laura Zagato
- Lee M. Kaplan
- Leena Peltonen
- Leif C. Groop
- Lenore J. Launer
- Liesbeth Vandenput
- Liming Liang
- Lina Zgaga
- Lorena Citterio
- Lu Qi
- Lyle J. Palmer
- M Weinstein
- M. Carola Zillikens
- M. Juhani Junttila
- Manfred Kayser
- Manuela Uda
- Mari Nelis
- Mari-Liis Tammesoo
- Marja-Liisa Lokki
- Marjo-Riitta Jarvelin
- Marjolein J. Peters
- Mark I. McCarthy
- Mark J. Caulfield
- Markku Koiranen
- Markku S. Nieminen
- Markus Perola
- Martin den Heijer
- Martin Farrall
- Martin Ridderstråle
- Martina Müller
- Mary F. Feitosa
- Massimo Mangino
- Matthew N. Cooper
- Mattias Lorentzon
- Michael A. Province
- Michael Boehnke
- Michael C. Turchin
- Michael E. Goddard
- Michael N. Weedon
- Michael Preuss
- Michael Stumvoll
- Mika Kähönen
- MN Weedon
- MN Weedon
- N Soranzo
- Najaf Amin
- Nancy L. Heard-Costa
- Neil R. Robertson
- Nelson B. Freimer
- Nicholas G. Martin
- Nicholas J. Wareham
- Nicola Glorioso
- Nicole L. Glazer
- Nicole Soranzo
- Nigel W. Rayner
- Niina Pellikka
- Nilanjan Chatterjee
- Nilesh J. Samani
- Olle Melander
- Olli Raitakari
- Ozren Polasek
- Paavo Zitting
- Pablo V. Gejman
- Panos Deloukas
- Patricia B. Munroe
- Paul Elliott
- Paul M. Ridker
- Per Hall
- Peter Almgren
- Peter Kovacs
- Peter Kraft
- Peter M. Visscher
- Peter P. Pramstaller
- PM Visscher
- Quince Gibson
- RA Fisher
- Rany M. Salem
- Reedik Mägi
- Richard B. Hayes
- Richard N. Bergman
- Robert C. Kaplan
- Robert J. Weyant
- Robert W. Lawrence
- Roberto Elosua
- Ruth J. F. Loos
- S Raychaudhuri
- S Sanna
- Sailaja Vedantam
- Samuli Ripatti
- Sarah H. Wild
- Sekar Kathiresan
- Seppo Koskinen
- Serena Sanna
- Shamika Ketkar
- Shaun Purcell
- Shen Haiqing
- SM Purcell
- Sonja I. Berndt
- Soumya Raychaudhuri
- SP Dickson
- Stefan Schreiber
- Stephen J. Chanock
- Suzanne Rafelt
- Sven Bergmann
- TA Manolio
- Talin Haritunians
- Tamara B. Harris
- Teresa Ferreira
- Terho Lehtimäki
- Themistocles L. Assimes
- Thomas Illig
- Thomas Kocher
- Thomas Meitinger
- Thomas Quertermous
- Thomas W. Winkler
- Thor Aspelund
- Timothy D. Spector
- Timothy M. Frayling
- Toby Johnson
- Tom H. Mosley Jr
- Tomi Pastinen
- Tony Kwan
- Tsegaselassie Workalemahu
- Tuomas O. Kilpeläinen
- Tushar Bhangale
- Tõnu Esko
- Ulf Gyllensten
- Ulla Sovio
- Unnur Thorsteinsdottir
- Valgerdur Steinthorsdottir
- Veikko Salomaa
- Veronique Vitart
- Vilmundur Gudnason
- Vincent Mooser
- Wendy L. McArdle
- Willem H. Ouwehand
- Wilmar Igl
- Wolfgang Hoffman
- Yurii S. Aulchenko
- Zoltán Kutalik
- Åsa Johansson
- Publication venue
- NATURE PUBLISHING GROUP
- Publication date
- 01/01/2010
- Field of study
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human traits, but these typically explain small fractions of phenotypic variation, raising questions about the use of further studies. Here, using 183,727 individuals, we show that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait. The large number of loci reveals patterns with important implications for genetic studies of common human diseases and traits. First, the 180 loci are not random, but instead are enriched for genes that are connected in biological pathways (P = 0.016) and that underlie skeletal growth defects (P < 0.001). Second, the likely causal gene is often located near the most strongly associated variant: in 13 of 21 loci containing a known skeletal growth gene, that gene was closest to the associated variant. Third, at least 19 loci have multiple independently associated variants, suggesting that allelic heterogeneity is a frequent feature of polygenic traits, that comprehensive explorations of already-discovered loci should discover additional variants and that an appreciable fraction of associated loci may have been identified. Fourth, associated variants are enriched for likely functional effects on genes, being over-represented among variants that alter amino-acid structure of proteins and expression levels of nearby genes. Our data explain approximately 10% of the phenotypic variation in height, and we estimate that unidentified common variants of similar effect sizes would increase this figure to approximately 16% of phenotypic variation (approximately 20% of heritable variation). Although additional approaches are needed to dissect the genetic architecture of polygenic human traits fully, our findings indicate that GWA studies can identify large numbers of loci that implicate biologically relevant genes and pathways.
Association of the PHACTR1/EDN1 genetic locus with spontaneous coronary artery dissection
- Author
- Adlam David
- Al-Hussaini Abtehale
- Alver Maris
- Anand Sonia S.
- Ardissino Diego
- Armasu Sebastian M.
- Assimes Themistocles L.
- Aubry Pierre
- Auro Kirsi
- Bali Laurent
- Barnay Pierre
- Bedossa Marc
- Belle Loïc
- Benamer Hakim
- Benamer Hakim
- Bertram Lars
- Beutner Frank
- Bjonnes Andrew
- Boerwinkle Eric
- Boiffard Emmanuel
- Borecki Ingrid B.
- Bottinger Erwin P.
- Bouajila Sara
- Bouatia-Naji Nabila
- Braund Peter S.
- Bresson Didier
- Brunel Philippe
- Buring Julie E.
- Caussin Christophe
- Cayla Guillaume
- Chambers John C.
- Champin Stanislas
- Chasman Daniel I.
- Chen Shufeng
- Clarke Robert
- Collins Rory
- Combaret Nicolas
- Commeau Philippe
- Cottin Yves
- Cupples L Adrienne
- Danesh John
- de Andrade Mariza
- de Andrade Mariza
- De Poli Fabien
- de Vries Paul S.
- Dedoussis George
- Dehghan Abbas
- Delarche Nicolas
- Deloukas Panos
- Demuth Ilja
- Dubreuil Olivier
- Ducrocq Grégory
- Dunwoodie Sally L.
- Dupouy Patrick
- d’Escamard Valentina
- Elosua Roberto
- Empana Jean-Philippe
- Epstein Stephen E.
- Erdmann Jeanette
- Esko Tõnu
- Farrall Martin
- Fatkin Diane
- Feitosa Mary F.
- Filippi Emmanuelle
- Fluttaz Arnaud
- Ford Ian
- Franceschini Nora
- Franco Oscar H.
- Franzosi Maria Grazia
- Frossard Philippe
- Gauguier Dominique
- Georges Adrien
- Georges Jean Louis
- Gerbaud Edouard
- Gerbay Antoine
- Giannoulatou Eleni
- Gieger Christian
- Gilard Martine
- Goel Anuj
- Goodall Alison H.
- Gottesman Omri
- Grace Christopher
- Graham Robert M.
- Granger Christopher B.
- Gu Dongfeng
- Gudnason Vilmundur
- Gulati Rajiv
- Gustafsson Stefan
- Haber Marc
- Hall Alistair S.
- Hall Leanne M.
- Hamsten Anders
- Han Bok-Ghee
- Harbaoui Brahim
- Harris Tamara B.
- Harvey Richard
- Hayes Sharonne N.
- Hazen Stanley L.
- Hengstenberg Christian
- Hofman Albert
- Holloway Cameron
- Hopewell Jemma C.
- Houpe David
- Huang Jianfeng
- Huang Jie
- Huang Siying
- Hwang Shih-Jen
- Iismaa Siiri E.
- Ingelsson Erik
- Iribarren Carlos
- Jalilzadeh Shapour
- Jeunemaitre Xavier
- Jouven Xavier
- Jukema J Wouter
- Kadian-Dodov Daniella
- Kanoni Stavroula
- Karhunen Pekka J.
- Karrillon Gaëtan
- Kathiresan Sekar
- Kessler Thorsten
- Kim Bong-Jo
- Kim Yun Kyoung
- Kleber Marcus E.
- Koning René
- Kooner Jaspal S.
- Kovacic Jason C.
- Kullo Iftikhar J.
- Kyriakou Theodosios
- König Inke R.
- Lannfelt Lars
- Lau King Wai
- Le Bivic Louis
- Lehtimäki Terho
- Lhermusier Thibault
- Lieb Wolfgang
- Lind Lars
- Lindgren Cecilia M.
- Lokki Maisa
- Loos Ruth J.
- Lu Xiangfeng
- Lu Yingchang
- Lyytikäinen Leo P.
- Magnusson Patrik K.
- Mallick Nadeem H.
- Manchuelle Aurélie
- Manzo-Silberman Stephane Peggy
- Margaritis Marios
- Marliere Stéphanie
- Mayaud Norbert
- Mazurkiewicz Stephani
- McGrath-Cadell Lucy
- McPherson Ruth
- Mehra Narinder
- Meitinger Thomas
- Melander Olle
- Memon Fazal-ur-Rehman
- Meneveau Nicolas
- Metspalu Andres
- Mihailov Evelin
- Mishra Ketan
- Monnier Arsène
- Morris Andrew P.
- Morrison Alanna
- Motreff Pascal
- Motreff Pascal
- Muller David
- März Winfried
- Nelson Christopher P.
- Nelson Christopher P.
- Nieminen Markku S.
- Nikpay Majid
- O'Byrne Megan M.
- O'Donnell Christopher J.
- Olin Jeffrey W.
- Olson Timothy M.
- Palmer Colin N.
- Pedersen Nancy L.
- Perola Markus
- Pervjakova Natalia
- Peters Annette
- Qu Liming
- Quertermous Thomas
- Rader Daniel J.
- Rallidis Loukianos S.
- Range Grégoire
- Rasheed Asif
- Reilly Muredach P.
- Ridker Paul M.
- Rioufol Gilles
- Ripatti Samuli
- Roberts Robert
- Rose Lynda M.
- Roule Vincent
- Saint-Etienne Christophe
- Saleheen Danish
- Salengro Emmanuel
- Salfati Elias
- Salomaa Veikko
- Samani Nilesh J.
- Samani Nilesh J.
- Samuel Maria
- Sanghera Dharambir K.
- Saxena Richa
- Scholz Markus
- Schunkert Heribert
- Schwartz Stephen M.
- Seedorf Udo
- Shah Svati H.
- Silvain Johanne
- Sinisalo Juha
- Smith Albert V.
- Spaulding Christian
- Stewart Alexandre F.
- Stirrups Kathleen E.
- Stott David J.
- Sweeting Michael
- Teiger Emmanuel
- Thiery Joachim
- Thompson John R.
- Tikkanen Emmi
- Trompet Stella
- Tweet Marysia S.
- Uitterlinden Andre
- Valla Mathieu
- Valy Yann
- van Zuydam Natalie R.
- Varenne Olivier
- Wang Laiyuan
- Watkins Hugh
- Webb Thomas R.
- Welch Catherine A.
- Willenborg Christina
- Won Hong-Hee
- Wong Claire Mei Yi
- Wood Alice
- Yang Xueli
- Zabalawi Amer
- Zalloua Pierre A.
- Zaman Khan S.
- Zeng Lingyao
- Zhang Weihua
- Zhao Wei
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background:
Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes (ACS) afflicting predominantly younger to middle-aged women. Observational studies have reported a high prevalence of extracoronary vascular anomalies, especially fibromuscular dysplasia (FMD) and a low prevalence of coincidental cases of atherosclerosis. PHACTR1/EDN1 is a genetic risk locus for several vascular diseases, including FMD and coronary artery disease, with the putative causal noncoding variant at the rs9349379 locus acting as a potential enhancer for the endothelin-1 (EDN1) gene.
Objectives:
This study sought to test the association between the rs9349379 genotype and SCAD.
Methods:
Results from case control studies from France, United Kingdom, United States, and Australia were analyzed to test the association with SCAD risk, including age at first event, pregnancy-associated SCAD (P-SCAD), and recurrent SCAD.
Results:
The previously reported risk allele for FMD (rs9349379-A) was associated with a higher risk of SCAD in all studies. In a meta-analysis of 1,055 SCAD patients and 7,190 controls, the odds ratio (OR) was 1.67 (95% confidence interval [CI]: 1.50 to 1.86) per copy of rs9349379-A. In a subset of 491 SCAD patients, the OR estimate was found to be higher for the association with SCAD in patients without FMD (OR: 1.89; 95% CI: 1.53 to 2.33) than in SCAD cases with FMD (OR: 1.60; 95% CI: 1.28 to 1.99). There was no effect of genotype on age at first event, P-SCAD, or recurrence.
Conclusions:
The first genetic risk factor for SCAD was identified in the largest study conducted to date for this condition. This genetic link may contribute to the clinical overlap between SCAD and FMD
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
- Author
- Abecasis GR
- Abecasis GR
- Abecasis Goncalo R.
- Absher D
- Absher D
- Aherrahrou Z
- Ahmadi KR
- Alavere Helene
- Alizadeh Behrooz Z.
- Altshuler D
- Altshuler David
- Amin Najaf
- Andersen K
- Andrews JS
- Aragam J
- Arking DE
- Arnett DK
- Arora Pankaj
- Aspelund T
- Aspelund T
- Aspelund Thor
- Assime TL
- Assimes TL
- Assimes TL
- Atkinson EJ
- Attwood T
- Aulchenko YS
- Aulchenko YS
- Aulchenko YS
- Aulchenko Yurii
- Badola S
- Bakker SJ
- Ball SG
- Balmforth AJ
- Bandinelli Stefania
- Barbalic M
- Barroso In S.
- Beckmann J
- Beckmann Jacques S.
- Beilby John P.
- Bekaert S
- Belz S
- Benjamin E
- Benjamin EJ
- Benjamin EJ
- Bergman Richard N.
- Bergmann Sven
- Bickel C
- Bilo HJ
- Bis J
- Bis JC
- Bis JC
- Bis Joshua C
- Blankenberg S
- Blankenberg S
- Blankenberg S
- Blettner M
- Boban M
- Boban Mladen
- Bochud M
- Bochud Murielle
- Boehnke Michael
- Boerwinkle E
- Boerwinkle E
- Boerwinkle E
- Boerwinkle E
- Boerwinkle Eric
- Boomsma Dorret I.
- Borecki I
- Bragg-Gresham Jennifer L.
- Brandstätter A
- Braund P
- Braund PS
- Breteler Monique
- Brown MJ
- Bruse P
- Buckley Brendan
- Burke Gregory L
- Burnett MS
- Burtt N
- Böger CA
- Böhm BO
- Cambien F
- Cambien F
- Campbell H
- Campbell S
- Campbell Harry
- Caulfield MJ
- Caulfield Mark J.
- Cavalieri M
- Chakravarti Aravinda
- Chambers JC
- Chambers John C.
- Chang PP
- Chasman DI
- Chasman Daniel I.
- Chen IY
- Chen L
- Chen L
- Chen Yii-Der Ida
- Clarke Robert
- Cockcroft JR
- Collins Francis S.
- Connell JM
- Cook HT
- Cooper J
- Coresh J
- Cornelia M. McEniery CM
- Cornelis MC
- Corre Tanguy
- Corsi Anna Maria
- Cotlarciuc I
- Couper D
- Crisp-Hihn A
- Cupples L
- Cupples LA
- Cupples LA
- Curhan GC
- D'Adamo Adamo Pio
- Dandona S
- Davey Smith G
- Davies Gail
- de Andrade M
- De Backer GG
- De Bacquer D
- de Boer IH
- De Buyzere ML
- De Geus Eco J. C.
- de Jong PE
- De Meyer T
- de Silva R
- Deary Ian J.
- Debette Stéphanie
- Deckers JW
- Dehghan A
- Dehghan A
- Dehghan A
- Dehghan A
- Dehghan A
- Del Greco M Fabiola
- Deloukas P
- Deloukas P
- Demissie S
- Demissie-Banjaw S
- Deng G
- Destefano Anita L.
- Devaney J
- Devuyst O
- Dikkeschei LD
- Dimkovic N
- Ding J
- Dobnig H
- Dockrell M
- Doering A
- Dominiczak A
- Döring Angela
- Dörr M
- Dörr Marcus
- Eardman J
- Ebrahim S
- Eggermann T
- Ehret Georg B.
- Eiriksdottir G
- Eiriksdottir G
- Ellinghaus D
- Elliott P
- Elliott Paul
- Elosua R
- Emilsson Valur
- Endlich K
- Epstein SE
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann J
- Erdmann Jeanette
- Esko Tõnu
- Eyheramendy Susana
- Fabretto Antonella
- Facheris Maurizio
- Faletra Flavio
- Farrall M
- Farrall Martin
- Feitosa M
- Felix JF
- Felix JF
- Felix JF
- Felix SB
- Felix Janine F.
- Ferrucci L
- Ferrucci L
- Ferrucci L
- Ferrucci Luigi
- Fischer M
- Floege J
- Foad N
- Folsom A
- Folsom AR
- Fornage Myriam
- Forouhi NG
- Fortmann S
- Fox CS
- Fox ER
- Franke A
- Friedrich N
- Fu Jingyuan
- Fuchsberger C
- Gabriel SB
- Galan Pilar
- Gale DP
- Ganesh Santhi K.
- Gansevoort RT
- Gao X
- Gasparini Paolo
- Giallauria F
- Gibson Q
- Gider Pierre
- Gieger Christian
- Gillebert TC
- Glazer N
- Glazer NL
- Glazer NL
- Glazer NL
- Glazer Nicole L.
- Go A
- Goel Anuj
- Goodall AH
- Gottdiener JS
- Gottdiener JS
- Gracey J
- Grammer TB
- Gray E
- Greiser KH
- Gretarsdottir S
- Groop Leif
- Grosshennig A
- Grosshennig A
- Gudnason V
- Gudnason V
- Gudnason V
- Gudnason Vilmundur
- Guiducci C
- Gulcher JR
- Gulde S
- Guo Xiuqing
- Gwilliams R
- Gyllensten U
- Gyllensten Ulf B.
- Hadley David
- Haerting J
- Hakonarson HH
- Hall A
- Hall AS
- Haller Toomas
- Halperin E
- Halperin E
- Hamburg NM
- Hamsten Anders
- Han X
- Haritunians T
- Haritunians T
- Haritunians T
- Harris T
- Harris TB
- Harris TB
- Harris Tamara B.
- Hastie N
- Hayward C
- Hayward Caroline
- Heath Simon
- Heckbert S
- Heckbert SR
- Heckbert SR
- Hedblad B
- Heid IM
- Heimerl S
- Hengstenberg C
- Hengstenberg C
- Hengstenberg C
- Hengstenberg C
- Henneman Peter
- Hepkema BG
- Hercberg Serge
- Hernandez Dena
- Hernandez-Fuentes M
- Herrington DM
- Hlatky M
- Hoen Peter A. C. T.
- Hoffmann MM
- Hofman A
- Hofman A
- Hofman A
- Hofman A
- Hofman A
- Hofman Albert
- Holm H
- Holm H
- Holm Hilma
- Homan van der Heide JJ
- Homuth G
- Hopewell Jemma C.
- Hottenga Jouke-Jan
- Howard TD
- Hu FB
- Hung Joseph
- Hwang SJ
- Hwang Shih-Jen
- Hypponen E
- Igl W
- Igl Wilmar
- Illig T
- Illig T
- Imboden M
- Ingelsson E
- Iribarren C
- Isaacs A
- Isaacs A
- Jackson Anne U.
- Janssens A Cecile J. W.
- Jarinova O
- Jarvelin MR
- Jarvelin Marjo-Riitta
- Jewell E
- Johansson A
- Johnson AD
- Johnson AD
- Johnson T
- Johnson Andrew D.
- Johnson Toby
- Jolley J
- Jukema J Wouter
- Kao WH
- Kardia SL
- Kathiresan S
- Kathiresan S
- Kathiresan S
- Kathiresan S
- Kathiresan S
- Kedenko L
- Keis Aime
- Kent KM
- Ketkar S
- Khaw Kay-Tee
- Kleber M
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- Zeginigg Marion
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- Zhang Weihua
- Zhao Jing Hua
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- Zweiker R
- Publication venue
- Nat Genet
- Publication date
- 01/01/2011
- Field of study
Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we identified at genome-wide significance (P = 2.7 × 10(-8) to P = 2.3 × 10(-13)) four new PP loci (at 4q12 near CHIC2, 7q22.3 near PIK3CG, 8q24.12 in NOV and 11q24.3 near ADAMTS8), two new MAP loci (3p21.31 in MAP4 and 10q25.3 near ADRB1) and one locus associated with both of these traits (2q24.3 near FIGN) that has also recently been associated with SBP in east Asians. For three of the new PP loci, the estimated effect for SBP was opposite of that for DBP, in contrast to the majority of common SBP- and DBP-associated variants, which show concordant effects on both traits. These findings suggest new genetic pathways underlying blood pressure variation, some of which may differentially influence SBP and DBP
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1
- Author
- Abecasis Gonçalo R.
- Absher Devin
- Adrienne Cupples L.
- Aherrahrou Zouhair
- Allayee Hooman
- Allione Alessandra
- Altshuler David
- Amin Najaf
- Anand Sonia S.
- Andersen Karl
- Anderson Jeffrey L.
- Angelica Merlini Pier
- Ardissino Diego
- Ardlie Kristin
- Assimes Themistocles L.
- Aulchenko Yurii S.
- Baas Annette F.
- Badger Stephen A.
- Balkau Beverley
- Ball Stephen G.
- Balmforth Anthony J.
- Bandinelli Stefania
- Barbalic Maja
- Barnes Timothy A.
- Barroso Inês
- Becker Diane M.
- Becker Lewis C.
- Beckmann Jacques S.
- Benediktsson Rafn
- Bengtsson Boström Kristina
- Bennett Amanda J.
- Berger Klaus
- Berglund Göran
- Bergman Richard N.
- Bingham Sheila A.
- Bis Joshua C.
- Blagieva Roza
- Blair Ross D.
- Blankenberg Stefan
- Blankensteijn Jan D.
- Bochud Murielle
- Boehm Bernhard O.
- Boehnke Michael
- Boerwinkle Eric
- Bonnycastle Lori L.
- Bots Michiel L.
- Bown Matthew J.
- Bradley Declan T.
- Bragi Walters G.
- Braund Peter S.
- Bravenboer Bert
- Brown Morris
- Bumpstead Suzannah
- Burnand Kevin
- Burton Paul R.
- Burtt Noël P.
- Buysschaert Ian
- Cambien Francois
- Campbell Harry
- Carlquist John F.
- Cauchi Stephane
- Caulfield Mark
- Chambers John C.
- Charpentier Guillaume
- Chen Li
- Child Anne H.
- Chines Peter S.
- Cichon Sven
- Clarke Robert
- Clough Rachel E.
- Cockerill Gillian
- Codd Veryan
- Coin Lachlan
- Connell John M.
- Cornelis Marilyn
- Couper David J.
- Crawford Gabe
- Crawford Gabriel J.
- Daly Mark J.
- Davies Robert W.
- de Faire Ulf
- de Graaf Jacqueline
- de Jong Paul E.
- Dedoussis George
- Dehghan Abbas
- Deloukas Panos
- Demissie Serkalem
- Devaney Joseph M.
- Di Gregorio Alessandra
- Diemert Patrick
- Dina Christian
- Do Ron
- Doering Angela
- Dominiczak Anna
- Doney Alex S. F.
- Dupuis Josée
- Döring Angela
- Dörr Marcus
- Edkins Sarah
- Eifert Sandra
- El Mokhtari Nour Eddine
- Elliott Amanda L.
- Elliott Katherine S.
- Elliott Katherine S.
- Elliott Paul
- Ellis Stephen G.
- Elosua Roberto
- Engert James C.
- Epstein Stephen E.
- Erdmann Jeanette
- Erdos Michael R.
- Eriksson Per
- Ernst Florian
- Eyheramendy Susana
- Farrall Martin
- Felix Stephan B.
- Ferreira Teresa
- Ferrucci Luigi
- Fischer Marcus
- Florez Jose C.
- Folkersen Lasse
- Folsom Aaron R.
- Forouhi Nita G.
- Fox Caroline S.
- Franco-Cereceda Anders
- Franklin Christopher S.
- Frayling Timothy M.
- Freimer Nelson B.
- Freyer Jennifer
- Frikke-Schmidt Ruth
- Froguel Philippe
- Futers Simon
- Galan Pilar
- Ganser Martha
- Gateva Vesela
- Gerry Hill B.
- Gieger Christian
- Gigante Bruna
- Girelli Domenico
- Gloyn Anna L.
- Goel Anuj
- Golledge Jonathan
- Goodall Alison H.
- Grallert Harald
- Grarup Niels
- Green Todd
- Gretarsdottir Solveig
- Griffin Simon
- Grobbee Diederick E.
- Groop Leif
- Groves Christopher J.
- Guarrera Simonetta
- Gudnason Vilmundur
- Guiducci Candace
- Gulcher Jeffrey R.
- Gut Ivo G.
- Gwilliam Rhian
- Gyllensten Ulf
- Hadjadj Samy
- Hadley David
- Hafez Hany
- Hall Alistair S.
- Halperin Eran
- Hammond Naomi
- Hamsten Anders
- Hansen Torben
- Harrison Seamus C.
- Hartikainen Anna-Liisa
- Hassanali Neelam
- Hattersley Andrew T.
- Hazen Stanley L.
- Heath Simon C.
- Hengstenberg Christian
- Hercberg Serge
- Herder Christian
- Hide Winston A.
- Hill Andrew A.
- Hitman Graham A.
- Hofman Albert
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- Holm Hilma
- Homuth Georg
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- Hu Frank B.
- Hua Zhao Jing
- Hughes Anne E.
- Humphries Steve E.
- Hunt Sarah E.
- Hunter David J.
- Huth Cornelia
- Hveem Kristian
- Illig Thomas
- Iribarren Carlos
- Isomaa Bo
- Jackson Anne U.
- Jarvelin Marjo-Riitta
- Johnson Anne
- Johnson Paul R. V.
- Johnson Toby
- Jones Gregory T.
- Jousilahti Pekka
- Jørgensen Torben
- Kaiser Michael A.
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- Kathiresan Sekar
- Khaw Kay-Tee
- Kiemeney Lambertus A.
- Klopp Norman
- Knowles Joshua W.
- Kolovou Genovefa
- Kong Augustine
- Kooner Jaspal S.
- Kraft Peter
- Kuusisto Johanna
- König Inke R.
- Laakso Markku
- Laaksonen Reijo
- Laan Maris
- Lakatta Edward G.
- Lambrechts Diether
- Langenberg Claudia
- Lauritzen Torsten
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- Lindgren Cecilia M.
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- Lucas Gavin
- Lyssenko Valeriya
- Mannucci Pier M.
- Maouche Seraya
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- Marre Michel
- Marrugat Jaume
- Martinelli Nicola
- Matthiasson Stefan E.
- Matthijs Boekholdt S.
- Matullo Giuseppe
- McArdle Wendy L.
- McCarroll Steve A.
- McCarthy Mark I.
- McCulloch Laura J.
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- Meigs James B.
- Meisinger Christa
- Meitinger Thomas
- Melander Olle
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- Munroe Patricia B.
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- Mühleisen Thomas W.
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- Nahrstaedt Janja
- Naik Dilip K.
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- Narisu Narisu
- Navarro Pau
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- Olivieri Oliviero
- Onland-Moret N. Charlotte
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- Palmen Jutta
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- Papadakis Konstantinos
- Patel Riyaz S.
- Patterson Chris C.
- Payne Felicity
- Peden John F.
- Pedersen Oluf
- Peltonen Leena
- Perola Markus
- Perry John R. B.
- Peters Annette
- Petersen Ann-Kristin
- Peyvandi Flora
- Pfeufer Arne
- Platou Carl
- Polidoro Silvia
- Potter Simon
- Pouta Anneli
- Powell Janet T.
- Pramstaller Peter P.
- Preuss Michael
- Proença Christine
- Prokopenko Inga
- Qi Lu
- Qu Liming
- Quertermous Thomas
- Quyyumi Arshed A.
- Rader Daniel J.
- Rallidis Loukianos S.
- Rathmann Wolfgang
- Raychaudhuri Soumya
- Reffelmann Thorsten
- Refstrup Mette
- Reilly Muredach P.
- Rettig Rainer
- Ricceri Fulvio
- Rice Catherine
- Roberts Robert
- Robertson Neil R.
- Rocheleau Ghislain
- Roden Michael
- Romanazzi Valeria
- Rosendaal Frits R.
- Rubin Diana
- Rudan Igor
- Sacerdote Carlotta
- Salomaa Veikko
- Samani Nilesh J.
- Sampson Michael J.
- Sandhu Manjinder S.
- Sanna Serena
- Saxena Richa
- Sayers Robert D.
- Schadt Eric
- Scheet Paul
- Schillert Arne
- Schlessinger David
- Schreiber Stefan
- Schrezenmeir Jürgen
- Schunkert Heribert
- Schwartz Stephen M.
- Schäfer Arne
- Scott D Julian A.
- Scott Laura J.
- Scuteri Angelo
- Seedorf Udo
- Segrè Ayellet V.
- Shields Beverley M.
- Shrader Peter
- Sigurdsson Gunnar
- Sijbrands Eric
- Siscovick David S.
- Sivananthan Mohan
- Sivapalaratnam Suthesh
- Sladek Rob
- Smith Alberto
- Smith Andrew J.
- Smith Tamara B.
- Snieder Harold
- Snoep Jaapjan D.
- Sohrabi Soroush
- Song Kijoung
- Soranzo Nicole
- Sparsø Thomas
- Spector Tim D.
- Spertus John A.
- Stark Klaus
- Stefansson Kari
- Stein Lincoln D.
- Steinthorsdottir Valgerdur
- Stewart Alexandre F. R.
- Stirrups Kathy
- Stoll Monika
- Strachan David P.
- Strassburger Klaus
- Stringham Heather M.
- Subirana Isaac
- Sun Qi
- Susan Burnett Mary
- Swift Amy J.
- Sylvius Nicolas
- Syvänen Ann-Christine
- Tanaka Toshiko
- Teijink Joep A. W.
- Tennstedt Stephanie
- Teumer Alexander
- Thompson John R.
- Thompson Matthew M.
- Thomson Ian A.
- Thorand Barbara
- Thorgeirsson Gudmundur
- Thorleifsson Gudmar
- Thorsteinsdottir Unnur
- Tichet Jean
- Tobin Martin D.
- Tognoni Giovanni
- Tomaszewski Maciej
- Topless Ruth
- Tuomi Tiinamaija
- Tuomilehto Jaakko
- Tybjærg-Hansen Anne
- Uda Manuela
- Uiterwaal Cuno S.
- Uitterlinden Andre
- Uitterlinden Andre G.
- Valle Timo T.
- van Bockxmeer Frank M.
- van Dam Rob M.
- van der Harst Pim
- van der Schouw Yvonne T.
- van Duijn Cornelia M.
- van Gilst Wiek H.
- van Haeften Timon W.
- van Herpt Thijs
- van Hoek Mandy
- van Rij Andre
- van Rij Andre M.
- van Vliet-Ostaptchouk Jana V.
- Vasudevan Thodur M.
- Vicky Phillips L.
- Vineis Paolo
- Voight Benjamin F.
- Vollenweider Peter
- Völker Uwe
- Völzke Henry
- Waeber Gerard
- Wain Louise V.
- Walker Mark
- Wallace Chris
- Waltham Matthew
- Wareham Nicholas J.
- Watanabe Richard M.
- Waterworth Dawn M.
- Watkins Hugh
- Webster John
- Weedon Michael N.
- Welch Ryan P.
- Wells George A.
- Wichmann H-Erich
- Wijmenga Cisca
- Wild John B.
- Wild Philipp S.
- Willenborg Christina
- Willer Cristen J.
- William Rayner N.
- Williams Frances M.
- Wilson Tang W. H.
- Wilson James F.
- Witteman Jaqueline C. M.
- Wouter Jukema J.
- Wright Benjamin J.
- Wu Guanming
- Ye Shu
- Yu Grace
- Yuan Xin
- Zeggini Eleftheria
- Zelenika Diana
- Zeller Tanja
- Zhai Guangju
- Zhang Feng
- Ziegler Andreas
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
Abdominal aortic aneurysm (AAA) is a common cause of morbidity and mortality and has a significant heritability. We carried out a genome-wide association discovery study of 1866 patients with AAA and 5435 controls and replication of promising signals (lead SNP with a p value < 1 × 10-5) in 2871 additional cases and 32,687 controls and performed further follow-up in 1491 AAA and 11,060 controls. In the discovery study, nine loci demonstrated association with AAA (p < 1 × 10-5). In the replication sample, the lead SNP at one of these loci, rs1466535, located within intron 1 of low-density-lipoprotein receptor-related protein 1 (LRP1) demonstrated significant association (p = 0.0042). We confirmed the association of rs1466535 and AAA in our follow-up study (p = 0.035). In a combined analysis (6228 AAA and 49182 controls), rs1466535 had a consistent effect size and direction in all sample sets (combined p = 4.52 × 10-10, odds ratio 1.15 [1.10-1.21]). No associations were seen for either rs1466535 or the 12q13.3 locus in independent association studies of coronary artery disease, blood pressure, diabetes, or hyperlipidaemia, suggesting that this locus is specific to AAA. Gene-expression studies demonstrated a trend toward increased LRP1 expression for the rs1466535 CC genotype in arterial tissues; there was a significant (p = 0.029) 1.19-fold (1.04-1.36) increase in LRP1 expression in CC homozygotes compared to TT homozygotes in aortic adventitia. Functional studies demonstrated that rs1466535 might alter a SREBP-1 binding site and influence enhancer activity at the locus. In conclusion, this study has identified a biologically plausible genetic variant associated specifically with AAA, and we suggest that this variant has a possible functional role in LRP1 expression
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
- Author
- Abecasis GR
- Abecasis Gonçalo R.
- Absher D
- Adair Linda S.
- Adeyemo Adebowale
- Aherrahrou Z
- Ahmadi KR
- Ala-Korpela Mika
- Alexander Myriam
- Altshuler D
- Altshuler David
- Amin Najaf
- Andersen K
- Aragam J
- Arfan Ikram M.
- Arking DE
- Arking Dan E.
- Arnett D
- Arora Pankaj
- Artigas Maria Soler
- Aspelund T
- Aspelund Thor
- Assimes TL
- Atkinson EJ
- Aulchenko YS
- Aulchenko YS
- Aulchenko YS
- Aulchenko Yurii
- Badola S
- Bakker SJ
- Bakker Stephan J. L.
- Ball SG
- Balmforth AJ
- Bandinelli Stefania
- Barbalic M
- Barroso Inês
- Beckmann J
- Beckmann Jacques S.
- Beilby John P.
- Benjamin E
- Benjamin EJ
- Bergman Richard N.
- Bergmann Sven
- Bickel C
- Bilo HJ
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- Bis Joshua C.
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- Boehnke Michael
- Boerwinkle E
- Boerwinkle E
- Boerwinkle E
- Boerwinkle Eric
- Bolton Judith A Hoffman
- Bonnycastle Lori L.
- Borecki I
- Bornstein Stefan R.
- Bots Michiel L.
- Bragg-Gresham Jennifer L.
- Brand Eva
- Brand Stefan-Martin
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- Publication venue
- Nature
- Publication date
- 01/01/2011
- Field of study
Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or ≥90 mm Hg diastolic blood pressure). Even small increments in blood pressure are associated with an increased risk of cardiovascular events. This genome-wide association study of systolic and diastolic blood pressure, which used a multi-stage design in 200,000 individuals of European descent, identified sixteen novel loci: six of these loci contain genes previously known or suspected to regulate blood pressure (GUCY1A3-GUCY1B3, NPR3-C5orf23, ADM, FURIN-FES, GOSR2, GNAS-EDN3); the other ten provide new clues to blood pressure physiology. A genetic risk score based on 29 genome-wide significant variants was associated with hypertension, left ventricular wall thickness, stroke and coronary artery disease, but not kidney disease or kidney function. We also observed associations with blood pressure in East Asian, South Asian and African ancestry individuals. Our findings provide new insights into the genetics and biology of blood pressure, and suggest potential novel therapeutic pathways for cardiovascular disease prevention
New genetic loci link adipose and insulin biology to body fat distribution.
- Author
- Aalto Ville
- Aasarød Knut
- Abecasis Goncalo R
- Abecasis Gonçalo
- Absher Devin
- Adair Linda S
- Adam Martin
- Adeyemo Adebowale
- Ahlqvist Emma
- Ahmadi Kourosh R
- Ahola Aila
- Ainali Chrysanthi
- Akylbekova Ermeg
- Ala-Korpela Mika
- Alavere Helen
- Albagha Omar M E
- Albrecht Eva
- Alen Markku
- Alexander Myriam
- Alhenc-Gelas François
- Alizadeh Behrooz Z
- Allison Matthew A
- Alonso Nerea
- Altshuler David
- Ambite Jose Luis
- Amin Najaf
- Amouyel Philippe
- An Ping
- Anderson Carl A
- Anderson Denise
- Anderson Garnet
- Andrews Jeanette S
- Antonella Mulas
- Antti Jula
- Aragaki Aaron K
- Arking Dan E
- Arnold Alice
- Arnold Alice M
- Arora Pankaj
- Arscott Gillian M
- Artigas Maria Soler
- Arveiler Dominique
- Asiki Gershim
- Aspelund Thor
- Assimes Themistocles L
- Atalay Mustafa
- Atkinson Elizabeth J
- Aulchenko Yurii
- Avery Christy
- Bain Stephen C
- Bakker Stephan J L
- Balcells Susana
- Balkau Beverley
- Ballantyne Christie M
- Balmforth Anthony J
- Bandinelli Stefania
- Barbalic Maja
- Barrett Amy
- Barroso Ines
- Barroso Inês
- Basart Hanneke
- Basart Hanneke V
- Bataille Veronique
- Baumert Jens
- Beckmann Jacques S
- Beekman Marian
- Been Latonya F
- Beilby John
- Beilby John P
- Bell Jordana T
- Bellis Claire
- Bennett Amanda J
- Bennett Franklyn
- Berenson Gerald S
- Bergman Richard N
- Bergmann Sven
- Berndt Sonja I
- Berne Christian
- Bidulescu Aurelian
- Bielak Lawrence F
- Bierut Laura J
- Biffar Reiner
- Bis Joshua C
- Blackburn Hannah
- Blangero John
- Blankenberg Stefan S
- Blüher Matthias
- Boban Mladen
- Bochud Murielle
- Boehm Bernhard O
- Boehnke Michael
- Boerwinkle Eric
- Boezen H Marike
- Bolton Jennifer L
- Bolton Judith A Hoffman
- Bonnet Fabrice
- Bonnycastle Lori L
- Boomsma Dorret I
- Borecki Ingrid
- Boright Andrew P
- Borja Judith B
- Bornstein Stefan R
- Boston Jonathan
- Bots Michiel L
- Bouatia-Naji Nabila
- Bouchard Claude
- Bovet Pascal
- Boyd Heather A
- Bragg-Gresham Jennifer L
- Brambilla Paolo
- Brand Eva
- Brand Stefan-Martin
- Brandi Maria Luisa
- Braund Peter S
- Brennan Eoin P
- Brismar Kerstin
- Brody Jennifer
- Broekmans Frank J
- Broer Linda
- Brown Matthew A
- Brown Morris J
- Brown-Gentry Kristin
- Bruinenberg Marcel
- Buchkovich Martin L
- Buckley Brendan M
- Buil Alfonso
- Bull Shelley B
- Burgdorf Christof
- Buring Julie E
- Burnett Mary S
- Burnier Michel
- Burri Andrea
- Burton Paul R
- Bush William S
- Busonero Fabio
- Buxbaum Sarah G
- Buyske Steve
- Buzkova Petra
- Byrne Enda M
- Böger Carsten A
- Böhringer Stefan
- Böttcher Yvonne
- Cambien Francois
- Campbell Harry
- Campbell Susan
- Carba Delia B
- Carlson Chris
- Carlson Olga D
- Carty Cara
- Casas Juan P
- Caspersen Ida H
- Castano-Betancourt Martha
- Cauchi Stéphane
- Cauley Jane A
- Caulfield Mark
- Cavalieri Margherita
- Cazier Jean-Baptiste
- Center Jacqueline R
- Cesana Giancarlo
- Chakravarti Aravinda
- Chambers John
- Chandak Giriraj R
- Chang Hsing-Yi
- Chang Yen-Pei C
- Chanock Stephen J
- Charchar Fadi J
- Chasman Dan
- Chaturvedi Nish
- Chen Constance
- Chen Han
- Chen Ida
- Chen Jin
- Chen Ming-Huei
- Chen Wei
- Chen Yii-Der Ida
- Cheng Iona
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- Surdulescu Gabriela
- Svensson Olle
- Swan Elizabeth J
- Swertz Morris A
- Swift Amy J
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- Tammesoo Mar-Liis
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- Vedantam Sailaja
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- Verlaan Dominique
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- Wichmann H-Erich
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- Wiggins Kerri L
- Wijmenga Cisca
- Wijnands-van Gent Colette J M
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- Wild Sarah H
- Wilk Alicja
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- Willemsen Gonneke
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- Willenborg Christina
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- Williams Winfred W
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- Wilson James F
- Wilson James G
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- Wilson Scott G
- Winkler Thomas
- Witteman Jacqueline C
- Witteman Jacqueline C M
- Wojczynski Mary K
- Wolffenbuttel Bruce H R
- Wong Andrew
- Wong Tien Y
- Woo Jean
- Wood Andrew R
- Wood Andy
- Workalemahu Tsegaselassie
- Wright Alan F
- Wu Chunyuan
- Wu Joseph M W
- Wu Ying
- Würtz Peter
- Xiao Su-Mei
- Yajnik Chittaranjan S
- Yang Jian
- Yang Qiong
- Yang Tsun-Po
- Yao Jie
- Yengo Loïc
- Yerges-Armstrong Laura M
- Young Alicia
- Young Elizabeth H
- Young J H
- Young Lauren
- Yuan Xin
- Zaboli Ghazal
- Zalloua Pierre A
- Zarrabeitia María T
- Zelenika Diana
- Zemunik Tatijana
- Zerbini Gianpaolo
- Zgaga Lina
- Zhai Guangju
- Zhang Feng
- Zhang Qunyuan
- Zhang Weihua
- Zhao Jing Hua
- Zhao Wei
- Zheng Hou-Feng
- Zheng Wei
- Zhou Yanhua
- Zhu Haidong
- Zhu Kun
- Zhu Xiaofeng
- Zhuang Wei V
- Zhuang Wei Vivian
- Ziegler Andreas
- Zillikens M Carola
- Zimmermann Martina E
- Zitting Paavo
- Zondervan Krina T
- Zukowska-Szczechowska Ewa
- Zygmunt Marek
- Ärnlöv Johan
- Österholm Anne-May
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms
Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV
- Author
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adler Volker
- Adzic Petar
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akin Ilina Vasileva
- Alagoz Enver
- Albajar Carmen
- Albayrak Elif Asli
- Albergo Sebastiano
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alimena Juliette
- Alverson George
- Alves Gilvan
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anderson Jacob
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Warren
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Arora Sanjay
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asin Ivan
- Askew Andrew
- Aslanoglou Xenofon
- Assran Yasser
- Ata Metin
- Attikis Alexandros
- Aubin Alexandre
- Auffray Etiennette
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M
- Babb John
- Baber Mark
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahtiyar Hüseyin
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Monika
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbieri Richard
- Barbone Lucia
- Barfuss Anne-Fleur
- Bargassa Pedrame
- Barge Derek
- Baringer Philip
- Barker Anthony
- Barlas Esra
- Barnes Virgil E
- Barnett Bruce Arnold
- Barney David
- Barone Luciano
- Barth Christian
- Bartosik Nazar
- Basegmez Suzan
- Battilana Carlo
- Bauer Gerry
- Bauerdick Lothar AT
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bazterra Victor Eduardo
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beaupere Nicolas
- Beernaert Kelly
- Behnamian Hadi
- Behr Joerg
- Behrenhoff Wolf
- Behrens Ulf
- Beirão Da Cruz E Silva Cristóvão
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Alan James
- Bell Ken W
- Bellan Riccardo
- Bellato Marco
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Bencze Gyorgy
- Bendavid Joshua
- Benedetti Daniele
- Benelli Gabriele
- Benhabib Lamia
- Beni Noemi
- Benitez Jose F
- Benucci Leonardo
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Bergholz Matthias
- Beri Suman Bala
- Bernardes Cesar Augusto
- Bernardini Jacopo
- Bernet Colin
- Berry Douglas
- Berry Edmund
- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Bethani Agni
- Betts Russell Richard
- Bhardwaj Ashutosh
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bialkowska Helena
- Bian Jian-Guo
- Bianchi Giovanni
- Bianchini Lorenzo
- Bianco Stefano
- Biasini Maurizio
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bilki Burak
- Bilmis Selcuk
- Bisello Dario
- Bitioukov Sergei
- Blekman Freya
- Blobel Volker
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Blyweert Stijn
- Boccali Tommaso
- Bocci Andrea
- Bochenek Joseph
- Bodek Arie
- Bodlak Martin
- Boimska Bożena
- Bolla Gino
- Bolognesi Sara
- Bonacorsi Daniele
- Bonato Alessio
- Bondu Olivier
- Bontenackels Michael
- Boos Edouard
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Bortoletto Daniela
- Bose Suvadeep
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Boutle Sarah
- Bradmiller-Feld John
- Braibant-Giacomelli Sylvie
- Branca Antonio
- Branson James G
- Breedon Richard
- Breto Guillermo
- Breuker Horst
- Brew Christopher
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brinson Jessica
- Broccolo Giuseppe
- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brom Jean-Marie
- Brona Grzegorz
- Brooke James John
- Brown Robert M
- Brownson Eric
- Brun Hugues
- Bruner Christopher
- Bruno Giacomo
- Buchmann Marco-Andrea
- Buchmuller Oliver
- Bucinskaite Inga
- Bunkowski Karol
- Bunn Julian
- Buontempo Salvatore
- Burgmeier Armin
- Burkett Kevin
- Burton Darren
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H
- Butz Erik
- Bylsma Ben
- Bäni Lukas
- Böser Christian
- Cabrillo Iban Jose
- Caebergs Thierry
- Caillol Cécile
- Cakir Altan
- Calabria Cesare
- Calamba Aristotle
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Calligaris Luigi
- Calvert Brian
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- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Canelli Maria Florencia
- Cankocak Kerem
- Capiluppi Paolo
- Cappello Gigi
- Cardaci Marco
- Carlin Roberto
- Carlsmith Duncan
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Wagner
- Carver Matthew
- Casal Bruno
- Casarsa Massimo
- Casasso Stefano
- Casimiro Linares Edgar
- Castaldi Rino
- Castello Roberto
- Castilla-Valdez Heriberto
- Castro Andrea
- Caudron Adrien
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Ceard Ludivine
- Centis Vignali Matteo
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Chabert Eric Christian
- Chakaberia Irakli
- Chamizo Llatas Maria
- Chan Kwok Ming
- Chan Matthew
- Chang Paoti
- Chang Sunghyun
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Charaf Otman
- Charlot Claude
- Chasco Matthew
- Chasserat Julien
- Chatterjee Avishek
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Sushil
- Checchia Paolo
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Kuan-Hsin
- Chen Mingshui
- Chen Po-Hsun
- Chen Yi
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiochia Vincenzo
- Chiorboli Massimiliano
- Chlebana Frank
- Choi Minkyoo
- Choi Suyong
- Choi Young Kyu
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C
- Choudhury Somnath
- Christopher Grant
- Chu Jennifer
- Chwalek Thorsten
- Ciangottini Diego
- Ciesielski Robert
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R
- Clare Robert
- Clarida Warren
- Clement Emyr
- Clerbaux Barbara
- CMS Collaboration
- Cockerill David JA
- Codispoti Giuseppe
- Colafranceschi Stefano
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Contardo Didier
- Conte Eric
- Contreras-Campana Christian
- Contreras-Campana Emmanuel
- Conway John
- Conway Rylan
- Cooper Seth
- Cornelis Tom
- Correa Martins Junior Marcos
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Costantini Silvia
- Costanza Francesco
- Couderc Fabrice
- Coughlan John A
- Cousins Robert
- Covarelli Roberto
- Cowden Christopher
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cripps Nicholas
- Crucy Shannon
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Curry David
- Cussans David
- Custódio Analu
- Cutajar Michael
- Cutts David
- Cwiok Mikolaj
- Czellar Sandor
- D'Agnolo Raffaele Tito
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- Da Costa Eliza Melo
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dahmes Bryan
- Dahms Torsten
- Dalchenko Mykhailo
- Dall'Osso Martino
- Dallavalle Gaetano-Marco
- Damgov Jordan
- Danielson Thomas
- Das Souvik
- Daskalakis Georgios
- Dasu Sridhara
- Daubie Evelyne
- Dauncey Paul
- David Tinoco Mendes Andre
- Davies Gavin
- De Almeida Dias Flavia
- de Barbaro Pawel
- De Benedetti Abraham
- De Boer Wim
- De Cosa Annapaola
- De Filippis Nicola
- De Gruttola Michele
- De Guio Federico
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Oliveira Martins Carley
- De Palma Mauro
- De Roeck Albert
- de Trocóniz Jorge F
- De Visscher Simon
- De Wolf Eddi A
- Degano Alessandro
- Deisher Amanda
- Deiters Konrad
- Dejardin Marc
- Del Re Daniele
- Delaere Christophe
- Delannoy Andrés G
- Delgado Peris Antonio
- Dell'Orso Roberto
- Della Negra Michel
- Della Ricca Giuseppe
- Demaria Natale
- Demina Regina
- Demiragli Zeynep
- Demortier Luc
- Denegri Daniel
- Depasse Pierre
- Dermenev Alexander
- Descroix Alexis
- Dewanjee Ram Krishna
- Dhingra Nitish
- Di Giovanni Gian Piero
- Di Guida Salvatore
- Di Marco Emanuele
- Di Matteo Leonardo
- Diamond Brendan
- Diemoz Marcella
- Dierlamm Alexander
- Dietz Charles
- Dietz-Laursonn Erik
- Diez Pardos Carmen
- Dildick Sven
- Dilsiz Kamuran
- Dimitrov Anton
- Dinardo Mauro Emanuele
- Dishaw Adam
- Dissertori Günther
- Dittmann Jay
- Dittmar Michael
- Dittmer Susan
- Dobrzynski Ludwik
- Dobson Marc
- Dobur Didar
- Dolen James
- Dominguez Aaron
- Dominik Wojciech
- Domínguez Vázquez Daniel
- Donato Silvio
- Donegà Mauro
- Dooling Samantha
- Dordevic Milos
- Dorigo Tommaso
- Dorland Tyler
- Doroba Krzysztof
- Dos Reis Martins Thiago
- Dozen Candan
- Dragicevic Marko
- Dragoiu Cosmin
- Drell Brian Robert
- Dremin Igor
- Driga Olga
- Drozdetskiy Alexey
- Du Pree Tristan
- Du Ran
- Duarte Campderros Jordi
- Duarte Javier
- Dubinin Mikhail
- Duchardt Deborah
- Dudero Phillip Russell
- Dudko Lev
- Dugad Shashikant
- Duggan Daniel
- Dumanoglu Isa
- Dunne Patrick
- Dupont-Sagorin Niels
- Duric Senka
- Durkin Lloyd Stanley
- Duru Firdevs
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- Ferreira Parracho Pedro Guilherme
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- Filipovic Nicolas
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- Finger Miroslav
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- Focardi Ettore
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- Ford William T
- Forthomme Laurent
- Foudas Costas
- Fouz Maria Cruz
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- Garay Garcia Jasone
- Garcia Guillaume
- Garcia-Abia Pablo
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- Gascon Susan
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- Gasparini Ugo
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- Geurts Frank JM
- Ghete Vasile Mihai
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- Giakoumopoulou Viktoria Athina
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- Goncharov Maxim
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- Gonzalez Lopez Oscar
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- Goodell Joseph
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- Goy Lopez Silvia
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- Grab Christoph
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- Granier de Cassagnac Raphael
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- Hernandez Jose M
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- Korenkov Vladimir
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- Kortelainen Matti J
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- Skatchkov Nikolai
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- Smirnov Vitaly
- Smith Geoffrey
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- Smith John
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- Smith Wesley H
- Snigirev Alexander
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- Wallny Rainer
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- Waltenberger Wolfgang
- Wang Dayong
- Wang Fuqiang
- Wang Jian
- Wang Quan
- Wang Xianyou
- Wang Zheng
- Wardle Nicholas
- Wayand Stefan
- Wayne Mitchell
- Weber Hannsjoerg Artur
- Weber Hendrik
- Weber Martin
- Weber Matthias
- Weiler Thomas
- Weinberg Marc
- Welke Charles
- Wendland Lauri
- Weng Yao
- Werner Jeremy Scott
- West Christopher
- Wetzel James
- Whitbeck Andrew
- Whitmore Juliana
- Wickramage Nadeesha
- Wilbur Scott
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- Wilkinson Richard
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- Winn Dave
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- Wood Jeffrey Scott
- Wood John
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- Worm Steven
- Wright Douglas
- Wulsin Howard Wells
- Wulz Claudia-Elisabeth
- Wyslouch Bolek
- Wöhri Hermine Katharina
- Würthwein Frank
- Xiao Hong
- Xie Si
- Xie Wei
- Xu Lingshan
- Yagil Avraham
- Yalvac Metin
- Yang Fan
- Yang Mingming
- Yang Yong
- Yazgan Efe
- Yelton John
- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- York Andrew
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yücel Mete
- Zabel James
- Zabi Alexandre
- Zablocki Jakub
- Zaganidis Nicolas
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zeyrek Mehmet
- Zhang Jinzhong
- Zhang Linlin
- Zheng Yu
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zito Giuseppe
- Zou Wei
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio
Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan
- Author
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abdulsalam Abdulla
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adler Volker
- Adzic Petar
- Afanasiev Serguei
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Muhammad
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akgun Ugur
- Akin Ilina Vasileva
- Alagoz Enver
- Albajar Carmen
- Albayrak Elif Asli
- Albergo Sebastiano
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Alexander James
- Aliev Takhmasib
- Alimena Juliette
- Almeida Nuno
- Alverson George
- Alves Gilvan
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anastassov Anton
- Anderson Jacob
- Andrea Jeremy
- Andreev Valeri
- Andreev Vladimir
- Andreev Yuri
- Andrews Warren
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcidiacono Roberta
- Arenton Michael Wayne
- Arfaei Hessamaddin
- Argiro Stefano
- Arneodo Michele
- Arora Sanjay
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asghar Muhammad Irfan
- Asin Ivan
- Askew Andrew
- Aslanoglou Xenofon
- Assran Yasser
- Ata Metin
- Attikis Alexandros
- Auffray Etiennette
- Autermann Christian Tobias
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M.
- Babb John
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahtiyar Hüseyin
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Monika
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbone Lucia
- Barfuss Anne-Fleur
- Bargassa Pedrame
- Barge Derek
- Baringer Philip
- Barker Anthony
- Barlas Esra
- Barnett Bruce Arnold
- Barney David
- Barone Luciano
- Bartalini Paolo
- Barth Christian
- Bartosik Nazar
- Basegmez Suzan
- Battilana Carlo
- Bauer Gerry
- Bauerdick Lothar A. T.
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bazterra Victor Eduardo
- Bean Alice
- Beauceron Stephanie
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- Beaupere Nicolas
- Beernaert Kelly
- Behr Joerg
- Behrenhoff Wolf
- Behrens Ulf
- Beirão Da Cruz E Silva Cristóvão
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Alan James
- Bell Ken W.
- Bellan Riccardo
- Bellato Marco
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Bencze Gyorgy
- Bendavid Joshua
- Benedetti Daniele
- Benelli Gabriele
- Benhabib Lamia
- Beni Noemi
- Benitez Jose F.
- Benucci Leonardo
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Bergholz Matthias
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- Berry Edmund
- Berryhill Jeffrey
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- Betchart Burton
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- Betts Russell Richard
- Bhardwaj Ashutosh
- Bhat Pushpalatha C.
- Bhatnagar Vipin
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- Bhattacharya Satyaki
- Bhatti Anwar
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- Cerminara Gianluca
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- Chabert Eric Christian
- Chadwick Matthew
- Chakaberia Irakli
- Chamizo Llatas Maria
- Chan Kwok Ming
- Chan Matthew
- Chang Paoti
- Chang Sunghyun
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Charaf Otman
- Charlot Claude
- Chasco Matthew
- Chasserat Julien
- Chatrchyan Serguei
- Chatterjee Avishek
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Sushil
- Checchia Paolo
- Chen Guo-Ming
- Chen He-Sheng
- Chen Jie
- Chen Kai-Feng
- Chen Kuan-Hsin
- Chen Mingshui
- Chen Yi
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Chetluru Vasundhara
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiochia Vincenzo
- Chiorboli Massimiliano
- Chlebana Frank
- Choi Minkyoo
- Choi Suyong
- Choi Young Kyu
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C.
- Choudhury Somnath
- Christiansen Tim
- Christopher Grant
- Chuang Shan-Huei
- Chwalek Thorsten
- Ciesielski Robert
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
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- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R.
- Clare Robert
- Clarida Warren
- Clement Emyr
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- Cline David
- CMS Collaboration
- Coarasa Perez Jose Antonio
- Cockerill David J. A.
- Codispoti Giuseppe
- Colafranceschi Stefano
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Contardo Didier
- Conte Eric
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- Contreras-Campana Emmanuel
- Conway John
- Conway Rylan
- Cooper Seth
- Cornelis Tom
- Correa Martins Junior Marcos
- Cossutti Fabio
- Costa Marco
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- Costanza Francesco
- Couderc Fabrice
- Coughlan John A.
- Cousins Robert
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- De Gruttola Michele
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- De Jesus Damiao Dilson
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- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Oliveira Martins Carley
- De Palma Mauro
- De Roeck Albert
- de Trocóniz Jorge F.
- De Visscher Simon
- De Wolf Eddi A.
- Degano Alessandro
- Deisher Amanda
- Deiters Konrad
- Dejardin Marc
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- Sakuma Tai
- Sala Leonardo
- Salazar Ibarguen Humberto Antonio
- Salerno Roberto
- Salfeld-Nebgen Jakob
- Salur Sevil
- Salvati Emmanuele
- Sammet Jan
- Sanabria Juan Carlos
- Sanchez Ann - Karin
- Sander Christian
- Sanders David A.
- Sanders Stephen
- Sani Matteo
- Santanastasio Francesco
- Santaolalla Javier
- Santocchia Attilio
- Santoro Alberto
- Saoulidou Niki
- Sarangi Tapas
- Sarkar Subir
- Sasseville Michael
- Savin Alexander
- Savoy-Navarro Aurore
- Savrin Viktor
- Saxena Pooja
- Scarborough Tara
- Schael Stefan
- Schettler Hannes
- Schilling Frank-Peter
- Schizzi Andrea
- Schlein Peter
- Schleper Peter
- Schlieckau Eike
- Schmidt Alexander
- Schmidt Ringo
- Schmitt Michael Henry
- Schmitz Stefan Antonius
- Schnetzer Steve
- Schoerner-Sadenius Thomas
- Schott Gregory
- Schröder Matthias
- Schum Torben
- Schwick Christoph
- Schäfer Christoph
- Schöfbeck Robert
- Scodellaro Luca
- Searle Matthew
- Seez Christopher
- Segala Michael
- Seidel Markus
- Seitz Claudia
- Seixas Joao
- Sekmen Sezen
- Selvaggi Giovanna
- Selvaggi Michele
- Semenov Sergey
- Sen Niladri
- Sen Sercan
- Senghi Soares Mara
- Senkin Sergey
- Seo Hyunkwan
- Serban Alin Titus
- Serin Meltem
- Seva Tomislav
- Sever Ramazan
- Sexton-Kennedy Elizabeth
- Sgandurra Louis
- Sgaravatto Massimo
- Sguazzoni Giacomo
- Shah Mehar Ali
- Shalhout Shalhout
- Sharan Manoj
- Sharma Archana
- Sharma Archana
- Sharma Monika
- Sharma Seema
- Sharma Varun
- Sharma Vivek
- Sharp Peter
- Sheldon Paul
- Shepherd-Themistocleous Claire H.
- Shi Xin
- Shipsey Ian
- Shiu Jing-Ge
- Shivpuri Ram Krishen
- Shmatov Sergey
- Shoaib Muhammad
- Shrestha Shruti
- Shrinivas Amithabh
- Shukla Prashant
- Shumeiko Nikolai
- Sibille Jennifer
- Siegrist Patrice
- Sigamani Michael
- Sikler Ferenc
- Silkworth Christopher
- Silva Pedro
- Silvers David
- Silverwood Hamish
- Silvestris Lucia
- Simon Michal
- Simon Sean
- Simonetto Franco
- Simonis Hans-Jürgen
- Singh Anil
- Singh Gurpreet
- Singh Jasbir
- Singovsky Alexander
- Sinthuprasith Tutanon
- Sirois Yves
- Siroli Gian Piero
- Sirunyan Albert M.
- Skatchkov Nikolai
- Skhirtladze Nikoloz
- Skuja Andris
- Slaunwhite Jason
- Smirnov Igor
- Smirnov Vitaly
- Smith Geoffrey
- Smith James
- Smith John
- Smith Vincent J.
- Smith Wesley H.
- Snigirev Alexander
- Snoek Hella
- Snook Benjamin
- Snow Gregory R.
- Snowball Matthew
- Sobol Andrei
- Soffi Livia
- Sogut Kenan
- Sola Valentina
- Solano Ada
- Somalwar Sunil
- Son Dong-Chul
- Song Sanghyeon
- Sonmez Nasuf
- Sonnenschein Lars
- Sordini Viola
- Sorokin Pavel
- Spagnolo Paolo
- Spalding William J.
- Spanier Stefan
- Sparrow Alex
- Speer Thomas
- Sperka David
- Sphicas Paraskevas
- Spiegel Leonard
- Spiezia Aniello
- Spiga Daniele
- Spiridonov Alexander
- Spiropulu Maria
- Sprenger Daniel
- Squillacioti Paola
- Squires Michael
- St John Jason
- Stadie Hartmut
- Stahl Achim
- Staiano Amedeo
- Starodumov Andrei
- Staykova Zlatka
- Steggemann Jan
- Stein Matthias
- Steinbrück Georg
- Stenson Kevin
- Stephans George
- Stickland David
- Stieger Benjamin
- Stiliaris Efstathios
- Stober Fred-Markus Helmut
- Stolin Viatcheslav
- Stone Robert
- Stoye Markus
- Stoynev Stoyan
- Strauss Josef
- Stringer Robert
- Strobbe Nadja
- Strom Derek
- Stuart David
- Sturdy Jared
- Stöckli Fabian
- Suarez Gonzalez Juan
- Suarez Indara
- Sudano Elizabeth
- Sudhakar Katta
- Sulak Lawrence
- Sulimov Valentin
- Sultanov Georgi
- Summers Don
- Sumorok Konstanty
- Sumowidagdo Suharyo
- Sun Werner
- Sunar Cerci Deniz
- Sung Kevin
- Surat Ugur Emrah
- Suwonjandee Narumon
- Svintradze Irakli
- Svyatkovskiy Alexey
- Swain Sanjay Kumar
- Swanson Joshua
- Swartz Morris
- Symonds Philip
- Szillasi Zoltan
- Szleper Michal
- Sznajder Andre
- Sánchez Hernández Alberto
- Tabarelli de Fatis Tommaso
- Tadel Matevz
- Takahashi Maiko
- Takasugi Eric
- Tali Bayram
- Tambe Norbert
- Tamponi Umberto
- Tan Ping
- Tao Junquan
- Tapper Alexander
- Taroni Silvia
- Tatarinov Aysen
- Taurok Anton
- Tauscher Ludwig
- Tavernier Stefaan
- Taylor Lucas
- Temple Jeffrey
- Tenchini Roberto
- Teo Wee Don
- Teodorescu Liliana
- Teyssier Daniel
- Thea Alessandro
- Theofilatos Konstantinos
- Thom Julia
- Thomas Laurent
- Thomas Scott
- Thomassen Peter
- Thompson Joshua
- Thomsen Jan
- Thyssen Filip
- Thüer Sebastian
- Tiko Andres
- Tikvica Lucija
- Timciuc Vladlen
- Tiras Emrah
- Titov Maksym
- Tkaczyk Slawek
- Tlisov Danila
- To Wing
- Toback David
- Tomalin Ian R.
- Tomei Thiago
- Tonelli Manganote Edmilson José
- Tonelli Guido
- Tonjes Marguerite
- Tonwar Suresh C.
- Topakli Huseyin
- Topkar Anita
- Topsis-Giotis Iasonas
- Torassa Ezio
- Toropin Alexander
- Tosi Mia
- Tosi Nicolò
- Tosi Silvano
- Tourtchanovitch Leonid
- Traczyk Piotr
- Tran Nhan Viet
- Travaglini Riccardo
- Treberer-Treberspurg Wolfgang
- Treille Daniel
- Tricomi Alessia
- Triossi Andrea
- Tripathi Mani
- Trocino Daniele
- Trocsanyi Zoltan Laszlo
- Troendle Daniel
- Tropiano Antonio
- Troshin Sergey
- Tsamalaidze Zviad
- Tsirou Andromachi
- Tu Yanjun
- Tucker Jordan
- Tully Christopher
- Tumasyan Armen
- Tuo Shengquan
- Tuominen Eija
- Tuominiemi Jorma
- Tuovinen Esa
- Turkewitz Jared
- Turner Mark
- Turner Paul
- Tuuva Tuure
- Tuve Cristina
- Tytgat Michael
- Tyurin Nikolay
- Tzeng Yeng-Ming
- Ujvari Balazs
- Ulmer Keith
- Ulrich Ralf
- Uplegger Lorenzo
- Urscheler Christina
- Usai Emanuele
- Uvarov Lev
- Uzunian Andrey
- Vaandering Eric Wayne
- Valls Nil
- Valuev Vyacheslav
- Van Doninck Walter
- Van Haevermaet Hans
- Van Hove Pierre
- Van Mechelen Pierre
- Van Mulders Petra
- Van Onsem Gerrit Patrick
- Van Remortel Nick
- Van Spilbeeck Alex
- Vander Donckt Muriel
- Vander Velde Catherine
- Vanelderen Lukas
- Vanlaer Pascal
- Vardarli Fuat Ilkehan
- Varela Joao
- Varelas Nikos
- Vartak Adish
- Vavilov Sergey
- Vazquez Acosta Monica
- Vazquez Valencia Fabiola
- Veelken Christian
- Veeraraghavan Venkatesh
- Velasco Mayda
- Velicanu Dragos
- Velkovska Julia
- Venditti Rosamaria
- Venturi Andrea
- Verdier Patrice
- Verdini Piero Giorgio
- Veres Gabor Istvan
- Vergili Mehmet
- Vernieri Caterina
- Verwilligen Piet
- Verzetti Mauro
- Veszpremi Viktor
- Vesztergombi Gyorgy
- Veverka Jan
- Vidal Marono Miguel
- Vidal Richard
- Vila Ivan
- Vilar Cortabitarte Rocio
- Vilela Pereira Antonio
- Villasenor-Cendejas Luis Manuel
- Villella Ilaria
- Vinogradov Alexey
- Virdee Tejinder
- Viret Sébastien
- Vischia Pietro
- Vishnevskiy Dmitry
- Vitulo Paolo
- Vizan Garcia Jesus Manuel
- Vlasov Evgueni
- Vlimant Jean-Roch
- Vogel Helmut
- Volkov Alexey
- Volobouev Igor
- Volpe Roberta
- Vorobiev Igor
- Vorobyev Alexey
- Vorobyev Andrey
- Voutilainen Mikko
- Vuosalo Carl
- Vutova Mariana
- Wagner Stephen Robert
- Wagner-Kuhr Jeannine
- Wakefield Stuart
- Walker Matthew
- Wallny Rainer
- Walsh Roberval
- Walsh Sinead
- Waltenberger Wolfgang
- Wan Zongru
- Wang Dayong
- Wang Fuqiang
- Wang Jian
- Wang Minzu
- Wang Xianyou
- Wang Zheng
- Wardle Nicholas
- Wasserbaech Steven
- Wayand Stefan
- Wayne Mitchell
- Weber Hannsjoerg Artur
- Weber Hendrik
- Weber Martin
- Weber Matthias
- Weiler Thomas
- Weinberg Marc
- Wendland Lauri
- Weng Yao
- Werner Jeremy Scott
- West Christopher
- Wetzel James
- Whitbeck Andrew
- Whitmore Juliana
- Wickramage Nadeesha
- Wilbur Scott
- Wilken Rachel
- Wilkinson Richard
- Williams Thomas
- Willmott Carlos
- Wimpenny Stephen
- Winer Brian L.
- Winn Dave
- Winstrom Lucas
- Wissing Christoph
- Wittich Peter
- Wittmer Bruno
- Wolf Matthias
- Wolf Roger
- Wolfe Homer
- Wolszczak Weronika
- Womersley William John
- Won Steven
- Wood Darien
- Wood Jeffrey Scott
- Wood John
- Worm Steven
- Wright Douglas
- Wrochna Grzegorz
- Wu Weimin
- Wulz Claudia-Elisabeth
- Wyslouch Bolek
- Wöhri Hermine Katharina
- Würthwein Frank
- Xiao Hong
- Xie Si
- Xie Wei
- Xu Lingshan
- Yagil Avraham
- Yalvac Metin
- Yang Fan
- Yang Mingming
- Yang Yong
- Yang Zong-Chang
- Yazgan Efe
- Yelton John
- Yetkin Taylan
- Yi Kai
- Yilmaz Yetkin
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- Yoon Sungho
- York Andrew
- Yu Intae
- Yu Shin-Shan
- Yumiceva Francisco
- Yun Jae Chul
- Yücel Mete
- Zabel James
- Zabi Alexandre
- Zablocki Jakub
- Zaganidis Nicolas
- Zakaria Mohammed
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zeinali Maryam
- Zeise Manuel
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zeyrek Mehmet
- Zhang Jinzhong
- Zhang Linlin
- Zheng Yu
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
- Zielinski Marek
- Zito Giuseppe
- Zotto Pierluigi
- Zou Wei
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Riau University
- Publication date
- 01/01/2009
- Field of study
This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good
Juxtaposing BTE and ATE – on the role of the European insurance industry in funding civil litigation
- Author
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abdulsalam Abdulla
- Acosta Darin
- Acosta John Gabriel
- Adair Antony
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adiguzel Aytul
- Adler Volker
- Adzic Petar
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Muhammad
- Ahuja Sudha
- Akchurin Nural
- Akgun Bora
- Akgun Ugur
- Akin Ilina Vasileva
- Alagoz Enver
- Albajar Carmen
- Albayrak Elif Asli
- Albergo Sebastiano
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Alderweireldt Sara
- Aldá Júnior Walter Luiz
- Alexander James
- Aliev Takhmasib
- Alimena Juliette
- Almeida Nuno
- Alverson George
- Alves Gilvan
- Amapane Nicola
- Amsler Claude
- Anagnostou Georgios
- Anastassov Anton
- Anderson Jacob
- Andrea Jeremy
- Andreev Valeri
- Andreev Vladimir
- Andreev Yuri
- Andrews Warren
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Arcidiacono Roberta
- Arenton Michael Wayne
- Arfaei Hessamaddin
- Argiro Stefano
- Arneodo Michele
- Arora Sanjay
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asghar Muhammad Irfan
- Asin Ivan
- Askew Andrew
- Aslanoglou Xenofon
- Assran Yasser
- Ata Metin
- Attikis Alexandros
- Auffray Etiennette
- Autermann Christian Tobias
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avetisyan Aram
- Avila Carlos
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M.
- Babb John
- Bacchetta Nicola
- Bachmair Felix
- Bachtis Michail
- Baden Drew
- Baffioni Stephanie
- Bagliesi Giuseppe
- Bahtiyar Hüseyin
- Baillon Paul
- Bainbridge Robert
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ban Yong
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Monika
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Barbone Lucia
- Barfuss Anne-Fleur
- Bargassa Pedrame
- Barge Derek
- Baringer Philip
- Barker Anthony
- Barlas Esra
- Barnett Bruce Arnold
- Barney David
- Barone Luciano
- Bartalini Paolo
- Barth Christian
- Bartosik Nazar
- Basegmez Suzan
- Battilana Carlo
- Bauer Gerry
- Bauerdick Lothar A. T.
- Baumgartel Darin
- Baus Colin
- Bayshev Igor
- Bazterra Victor Eduardo
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beaupere Nicolas
- Beernaert Kelly
- Behr Joerg
- Behrenhoff Wolf
- Behrens Ulf
- Beirão Da Cruz E Silva Cristóvão
- Belforte Stefano
- Beliy Nikita
- Belknap Donald
- Bell Alan James
- Bell Ken W.
- Bellan Riccardo
- Beluffi Camille
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Bencze Gyorgy
- Bendavid Joshua
- Benedetti Daniele
- Benelli Gabriele
- Benhabib Lamia
- Beni Noemi
- Benitez Jose F.
- Benucci Leonardo
- Benussi Luigi
- Benvenuti Alberto
- Beranek Sarah
- Beretvas Andrew
- Bergauer Thomas
- Berger Joram
- Bergholz Matthias
- Beri Suman Bala
- Bernardes Cesar Augusto
- Bernardini Jacopo
- Bernet Colin
- Berry Douglas
- Berry Edmund
- Berryhill Jeffrey
- Bertl Willi
- Besancon Marc
- Betchart Burton
- Bethani Agni
- Betts Russell Richard
- Bhardwaj Ashutosh
- Bhat Pushpalatha C.
- Bhatnagar Vipin
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhatti Anwar
- Bialkowska Helena
- Bian Jian-Guo
- Bianchi Giovanni
- Bianchini Lorenzo
- Bianco Stefano
- Biasini Maurizio
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bilki Burak
- Bilmis Selcuk
- Bisello Dario
- Bitioukov Sergei
- Blekman Freya
- Blobel Volker
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Blyweert Stijn
- Boccali Tommaso
- Bocci Andrea
- Bochenek Joseph
- Bodek Arie
- Boimska Bożena
- Bolla Gino
- Bolognesi Sara
- Bonacorsi Daniele
- Bonato Alessio
- Bondu Olivier
- Bontenackels Michael
- Boos Edouard
- Bornheim Adolf
- Borras Kerstin
- Borrello Laura
- Bortignon Pierluigi
- Bortoletto Daniela
- Bose Suvadeep
- Bose Tulika
- Botta Cristina
- Boudoul Gaelle
- Bouhali Othmane
- Bourilkov Dimitri
- Boutle Sarah
- Braibant-Giacomelli Sylvie
- Branca Antonio
- Branson James G.
- Breedon Richard
- Breto Guillermo
- Breuker Horst
- Brew Christopher
- Brigliadori Luca
- Brigljevic Vuko
- Brinkerhoff Andrew
- Broccolo Giuseppe
- Brochero Cifuentes Javier Andres
- Brochet Sébastien
- Brom Jean-Marie
- Brona Grzegorz
- Brooke James John
- Brown Robert M.
- Brownson Eric
- Brun Hugues
- Bruno Giacomo
- Buchmann Marco-Andrea
- Buchmuller Oliver
- Bucinskaite Inga
- Bunichev Viacheslav
- Bunin Pavel
- Bunkowski Karol
- Bunn Julian
- Buontempo Salvatore
- Burgmeier Armin
- Burkett Kevin
- Burton Darren
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H.
- Butt Jamila
- Butz Erik
- Bylsma Ben
- Bäni Lukas
- Böser Christian
- Cabrillo Iban Jose
- Caebergs Thierry
- Caillol Cécile
- Cakir Altan
- Calabria Cesare
- Calamba Aristotle
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Calligaris Luigi
- Callner Jeremy
- Calpas Betty
- Calvert Brian
- Calvo Enrique
- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Cankocak Kerem
- Capiluppi Paolo
- Cappello Gigi
- Cardaci Marco
- Carlin Roberto
- Carlsmith Duncan
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Carroll Ryan
- Cartiglia Nicolo
- Carvalho Wagner
- Casal Bruno
- Casarsa Massimo
- Casasso Stefano
- Casimiro Linares Edgar
- Castaldi Rino
- Castello Roberto
- Castilla-Valdez Heriberto
- Castro Andrea
- Caudron Adrien
- Caudron Julien
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Ceard Ludivine
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Chabert Eric Christian
- Chadwick Matthew
- Chakaberia Irakli
- Chamizo Llatas Maria
- Chan Kwok Ming
- Chan Matthew
- Chang Paoti
- Chang Sunghyun
- Chang You-Hao
- Chang Yu-Wei
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Charaf Otman
- Charlot Claude
- Chasco Matthew
- Chasserat Julien
- Chatrchyan Serguei
- Chatterjee Avishek
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chauhan Sushil
- Checchia Paolo
- Chen Guo-Ming
- Chen He-Sheng
- Chen Jie
- Chen Kai-Feng
- Chen Kuan-Hsin
- Chen Mingshui
- Chen Yi
- Cheng Tongguang
- Cherepanov Vladimir
- Chertok Maxwell
- Chetluru Vasundhara
- Cheung Harry
- Chhibra Simranjit Singh
- Chierici Roberto
- Chinellato Jose
- Chiochia Vincenzo
- Chiorboli Massimiliano
- Chlebana Frank
- Choi Minkyoo
- Choi Suyong
- Choi Young Kyu
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C.
- Choudhury Somnath
- Christiansen Tim
- Christopher Grant
- Chuang Shan-Huei
- Chwalek Thorsten
- Ciesielski Robert
- Cihangir Selcuk
- Cimmino Anna
- Ciocci Maria Agnese
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R.
- Clare Robert
- Clarida Warren
- Clement Emyr
- Clerbaux Barbara
- Cline David
- CMS Collaboration
- Coarasa Perez Jose Antonio
- Cockerill David J. A.
- Codispoti Giuseppe
- Colafranceschi Stefano
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Contardo Didier
- Conte Eric
- Contreras-Campana Christian
- Contreras-Campana Emmanuel
- Conway John
- Conway Rylan
- Cooper Seth
- Cornelis Tom
- Correa Martins Junior Marcos
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Costantini Silvia
- Costanza Francesco
- Couderc Fabrice
- Coughlan John A.
- Cousins Robert
- Covarelli Roberto
- Cowden Christopher
- Cox Bradley
- Cox Peter Timothy
- Creanza Donato
- Cremaldi Lucien Marcus
- Cripps Nicholas
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Cussans David
- Custódio Analu
- Cutajar Michael
- Cutts David
- Cwiok Mikolaj
- Czellar Sandor
- D'Agnolo Raffaele Tito
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dahmes Bryan
- Dahms Torsten
- Dalchenko Mykhailo
- Dallavalle Gaetano-Marco
- Damgov Jordan
- Danielson Thomas
- Das Souvik
- Daskalakis Georgios
- Dasu Sridhara
- Daubie Evelyne
- Dauncey Paul
- David Tinoco Mendes Andre
- Davies Gavin
- De Almeida Dias Flavia
- de Barbaro Pawel
- De Benedetti Abraham
- De Boer Wim
- De Cosa Annapaola
- De Filippis Nicola
- De Gruttola Michele
- De Guio Federico
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Mattia Marco
- De Moraes Gregores Eduardo
- De Oliveira Martins Carley
- De Palma Mauro
- De Roeck Albert
- de Trocóniz Jorge F.
- De Visscher Simon
- De Wolf Eddi A.
- Degano Alessandro
- Deisher Amanda
- Deiters Konrad
- Dejardin Marc
- Del Re Daniele
- Delaere Christophe
- Delannoy Andrés G.
- Delgado Peris Antonio
- Dell'Orso Roberto
- Della Negra Michel
- Della Ricca Giuseppe
- Demaria Natale
- Demina Regina
- Demiragli Zeynep
- Demortier Luc
- Denegri Daniel
- Deniz Muhammed
- Depasse Pierre
- Dermenev Alexander
- Descroix Alexis
- Dhingra Nitish
- Di Giovanni Gian Piero
- Di Guida Salvatore
- Di Marco Emanuele
- Di Matteo Leonardo
- Diamond Brendan
- Diemoz Marcella
- Dierlamm Alexander
- Dietz Charles
- Dietz-Laursonn Erik
- Diez Pardos Carmen
- Dildick Sven
- Dilsiz Kamuran
- Dimitrov Anton
- Dinardo Mauro Emanuele
- Dissertori Günther
- Dittmann Jay
- Dittmar Michael
- Djordjevic Milos
- Dobrzynski Ludwik
- Dobson Marc
- Dobur Didar
- Doesburg Robert
- Dolen James
- Dominguez Aaron
- Dominik Wojciech
- Domínguez Vázquez Daniel
- Donegà Mauro
- Dooling Samantha
- Dorigo Tommaso
- Dorland Tyler
- Dorney Brian
- Doroba Krzysztof
- Dos Reis Martins Thiago
- Dosselli Umberto
- Dozen Candan
- Dragicevic Marko
- Dragoiu Cosmin
- Drell Brian Robert
- Dremin Igor
- Drouhin Frédéric
- Drozdetskiy Alexey
- Du Pree Tristan
- Duarte Campderros Jordi
- Duarte Javier
- Dubinin Mikhail
- Duchardt Deborah
- Dudero Phillip Russell
- Dudko Lev
- Dugad Shashikant
- Duggan Daniel
- Dumanoglu Isa
- Dupont-Sagorin Niels
- Duric Senka
- Durkin Lloyd Stanley
- Duru Firdevs
- Dutta Dipanwita
- Dutta Suchandra
- Dutta Valentina
- Dünser Marc
- Eckerlin Guenter
- Ecklund Karl Matthew
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- Zeuner Wolfram Dietrich
- Zeyrek Mehmet
- Zhang Jinzhong
- Zhang Linlin
- Zheng Yu
- Zhokin Alexander
- Zhu Ren-Yuan
- Zhukov Valery
- Zhukova Victoria
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- Zito Giuseppe
- Zotto Pierluigi
- Zou Wei
- Zsigmond Anna Julia
- Zucchetta Alberto
- Zumerle Gianni
- Zuranski Andrzej
- Publication venue
- Publication date
- 01/01/2010
- Field of study
One of the ways in which legal services are financed, and indeed shaped, is through private insurance arrangement. Two contrasting types of legal expenses insurance contracts (LEI) seem to dominate in Europe: before the event (BTE) and after the event (ATE) legal expenses insurance. Notwithstanding institutional differences between different legal systems, BTE and ATE insurance arrangements may be instrumental if government policy is geared towards strengthening a market-oriented system of financing access to justice for individuals and business. At the same time, emphasizing the role of a private industry as a keeper of the gates to justice raises issues of accountability and transparency, not readily reconcilable with demands of competition. Moreover, multiple actors (clients, lawyers, courts, insurers) are involved, causing behavioural dynamics which are not easily predicted or influenced.
Against this background, this paper looks into BTE and ATE arrangements by analysing the particularities of BTE and ATE arrangements currently available in some European jurisdictions and by painting a picture of their respective markets and legal contexts. This allows for some reflection on the performance of BTE and ATE providers as both financiers and keepers. Two issues emerge from the analysis that are worthy of some further reflection. Firstly, there is the problematic long-term sustainability of some ATE products. Secondly, the challenges faced by policymakers that would like to nudge consumers into voluntarily taking out BTE LEI
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