835 research outputs found

    The Role of Leguminous Browse Plants in a Cool Mediterranean Enviornment

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    There is considerable scope for improving the productivity and persistence of pasture systems, in the temperate low rainfall zones (\u3c 550 mm annual rainfall) of Australia and New Zealand. Alternative pasture species, including leguminous browse plants, have potential to increase the diversity and stability of these pasture systems. The genus Dorycnium (canary clover), has previously been identified as containing a number of species with desirable forage and soil conservation characteristics. Preliminary investigations have indicated that at least two species, D. rectum and D. hirsutum, produce significant quantities of forage in the year of establishment and are palatable to sheep. It is proposed that these plants may provide a valuable source of forage on land which currently lacks productive and persistent pasture. Forage produced by these plants would be allowed to accumulate in a ‘forage bank’ and used for strategic grazing during summer and autumn or for drought feeding

    Hesperian-Amazonian Transition Mid-Latitude Valleys: Markers of a Late Martian Climate Optima?

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    Recently the inventory of fluvial features that have been dated to the late Hesperian to early Amazonian epoch has increased dramatically, including a reassessment of the ages of the large alluvial fans and deltas (e.g., Eberswalde) to this time period. Mid-latitude Valleys (MLVs) are distinct from the older, more integrated Noachian-Hesperian Valley Networks which are deeply dissected, are generally of much larger spatial extent, and are more degraded. Although some MLVs involve rejuvenation of older Valley Networks, many MLVs are carved into smooth or rolling slopes and intercrater terrain. The MLVs range from a few meters to < 300 m in width, with nearly parallel valley walls and planforms that are locally sinuous. Although the MLVs in Newton and Gorgonum basins extend from the basin rims up to 75 km into the basin interior, most MLVs are shorter and often discontinuous. The occurrence of widespread MLVs suggest the possibility of their formation during one or perhaps more regional to global climatic episodes, possibly due to melting of seasonal to long-term accumulations of snow and ice. Temperatures warm enough to cause extensive melting may have occurred during optimal orbital and obliquity configurations, perhaps in conjunction with intensive volcanism releasing moisture and greenhouse gasses, or as a result of a brief episode of warming from a large impact. The concentration of MLVs to the northern and western basin slopes of Newton and Gorgonum basins suggests a possible aspect control to ice accumulation or melting. MLV activity occurred about at the same time as formation of the major outflow channels. A possible scenario is that delivery of water to the northern lowlands provided, through evaporation and sublimation, water that temporarily accumulated in the mid-southern latitudes as widespread ice deposits whose partial melting formed the MLVs and small, dominantly ice-covered lakes

    Morphology and tectonics of the Mid-Atlantic Ridge, 7°–12°S

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    We present swath bathymetric, gravity, and magnetic data from the Mid-Atlantic Ridge between the Ascension and the Bode Verde fracture zones, where significant ridge–hot spot interaction has been inferred. The ridge axis in this region may be divided into four segments. The central two segments exhibit rifted axial highs, while the northernmost and southernmost segments have deep rift valleys typical of slow-spreading mid-ocean ridges. Bathymetric and magnetic data indicate that both central segments have experienced ridge jumps since ~1 Ma. Mantle Bouguer anomalies (MBAs) derived from shipboard free air gravity and swath bathymetric data show deep subcircular lows centered on the new ridge axes, suggesting that mantle flow has been established beneath the new spreading centers for at least ~1 Myr. Inversion of gravity data indicates that crustal thicknesses vary by ~4 km along axis, with the thickest crust occurring beneath a large axial volcanic edifice. Once the effects of lithospheric aging have been removed, a model in which gravity variations are attributed entirely to crustal thickness variations is more consistent with data from an axis-parallel seismic line than a model that includes additional along-axis variations in mantle temperature. Both geophysical and geochemical data from the region may be explained by the melting of small (&lt;200 km) mantle chemical heterogeneities rather than elevated temperatures. Therefore, there may be no Ascension/Circe plume

    The Cyprinodon variegatus genome reveals gene expression changes underlying differences in skull morphology among closely related species

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    Genes in durophage intersection set at 15 dpf. This is a comma separated table of the genes in the 15 dpf durophage intersection set. Given are edgeR results for each pairwise comparison. Columns indicating whether a gene is included in the intersection set at a threshold of 1.5 or 2 fold are provided. (CSV 13 kb

    A systematic review and meta-synthesis of the impact of low back pain on people's lives

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    Copyright @ 2014 Froud et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.Background - Low back pain (LBP) is a common and costly problem that many interpret within a biopsychosocial model. There is renewed concern that core-sets of outcome measures do not capture what is important. To inform debate about the coverage of back pain outcome measure core-sets, and to suggest areas worthy of exploration within healthcare consultations, we have synthesised the qualitative literature on the impact of low back pain on people’s lives. Methods - Two reviewers searched CINAHL, Embase, PsycINFO, PEDro, and Medline, identifying qualitative studies of people’s experiences of non-specific LBP. Abstracted data were thematic coded and synthesised using a meta-ethnographic, and a meta-narrative approach. Results - We included 49 papers describing 42 studies. Patients are concerned with engagement in meaningful activities; but they also want to be believed and have their experiences and identity, as someone ‘doing battle’ with pain, validated. Patients seek diagnosis, treatment, and cure, but also reassurance of the absence of pathology. Some struggle to meet social expectations and obligations. When these are achieved, the credibility of their pain/disability claims can be jeopardised. Others withdraw, fearful of disapproval, or unable or unwilling to accommodate social demands. Patients generally seek to regain their pre-pain levels of health, and physical and emotional stability. After time, this can be perceived to become unrealistic and some adjust their expectations accordingly. Conclusions - The social component of the biopsychosocial model is not well represented in current core-sets of outcome measures. Clinicians should appreciate that the broader impact of low back pain includes social factors; this may be crucial to improving patients’ experiences of health care. Researchers should consider social factors to help develop a portfolio of more relevant outcome measures.Arthritis Research U

    Uncovering treatment burden as a key concept for stroke care: a systematic review of qualitative research

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    &lt;b&gt;Background&lt;/b&gt; Patients with chronic disease may experience complicated management plans requiring significant personal investment. This has been termed ‘treatment burden’ and has been associated with unfavourable outcomes. The aim of this systematic review is to examine the qualitative literature on treatment burden in stroke from the patient perspective.&lt;p&gt;&lt;/p&gt; &lt;b&gt;Methods and findings&lt;/b&gt; The search strategy centred on: stroke, treatment burden, patient experience, and qualitative methods. We searched: Scopus, CINAHL, Embase, Medline, and PsycINFO. We tracked references, footnotes, and citations. Restrictions included: English language, date of publication January 2000 until February 2013. Two reviewers independently carried out the following: paper screening, data extraction, and data analysis. Data were analysed using framework synthesis, as informed by Normalization Process Theory. Sixty-nine papers were included. Treatment burden includes: (1) making sense of stroke management and planning care, (2) interacting with others, (3) enacting management strategies, and (4) reflecting on management. Health care is fragmented, with poor communication between patient and health care providers. Patients report inadequate information provision. Inpatient care is unsatisfactory, with a perceived lack of empathy from professionals and a shortage of stimulating activities on the ward. Discharge services are poorly coordinated, and accessing health and social care in the community is difficult. The study has potential limitations because it was restricted to studies published in English only and data from low-income countries were scarce.&lt;p&gt;&lt;/p&gt; &lt;b&gt;Conclusions&lt;/b&gt; Stroke management is extremely demanding for patients, and treatment burden is influenced by micro and macro organisation of health services. Knowledge deficits mean patients are ill equipped to organise their care and develop coping strategies, making adherence less likely. There is a need to transform the approach to care provision so that services are configured to prioritise patient needs rather than those of health care systems

    Methanol maser associated outflows: detection statistics and properties

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    We have selected the positions of 54 6.7 GHz methanol masers from the Methanol Multibeam Survey catalogue, covering a range of longitudes between 20° and 34° of the Galactic plane. These positions were mapped in the J = 3-2 transition of both the 13CO and C18O lines. A total of 58 13CO emission peaks are found in the vicinity of these maser positions. We search for outflows around all 13CO peaks, and find evidence for high-velocity gas in all cases, spatially resolving the red and blue outflow lobes in 55 cases. Of these sources, 44 have resolved kinematic distances, and are closely associated with the 6.7 GHz masers, a subset referred to as Methanol Maser Associated Outflows (MMAOs). We calculate the masses of the clumps associated with each peak using 870 mum continuum emission from the ATLASGAL survey. A strong correlation is seen between the clump mass and both outflow mass and mechanical force, lending support to models in which accretion is strongly linked to outflow. We find that the scaling law between outflow activity and clump masses observed for low-mass objects, is also followed by the MMAOs in this study, indicating a commonality in the formation processes of low-mass and high-mass stars

    The state of the Martian climate

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    60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

    Performance of the CMS Cathode Strip Chambers with Cosmic Rays

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    The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns

    Müller glia provide essential tensile strength to the developing retina.

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    This is the final version of the article. It first appeared from the Rockefeller University Press via http://dx.doi.org/10.1083/jcb.201503115To investigate the cellular basis of tissue integrity in a vertebrate central nervous system (CNS) tissue, we eliminated Müller glial cells (MG) from the zebrafish retina. For well over a century, glial cells have been ascribed a mechanical role in the support of neural tissues, yet this idea has not been specifically tested in vivo. We report here that retinas devoid of MG rip apart, a defect known as retinoschisis. Using atomic force microscopy, we show that retinas without MG have decreased resistance to tensile stress and are softer than controls. Laser ablation of MG processes showed that these cells are under tension in the tissue. Thus, we propose that MG act like springs that hold the neural retina together, finally confirming an active mechanical role of glial cells in the CNS.This work was funded by a Herchel Smith Postdoctoral Fellowship to R.B.M., the Wellcome Trust programme in Developmental Biology to O.R. and J.O., NIH grants EY14358 (R.O.W.) and EY01730 (Vision Core), MRC Career Development Award and HFSP Young Investigator Grant to K.F., and a Wellcome Trust Investigator Award to W.A.H
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