202 research outputs found

    Ancient variants and exegesis for Il. 14.382

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    A detailed analysis of the scholiastic and Eustathian material concerning the variants \u3b4\u3cc\u3c3\u3ba\u3b5\u3bd / \u3b4\u3cc\u3c3\u3ba\u3bf\u3bd / \u3b4\u1ff6\u3ba\u3b5\u3bd in Il. 14.382 is performed. Examination of the manuscripts and an investigation into the history of the modern studies suggests it is more plausible to conclude that the reading attributed to Aristarchus in the scholia was \u3b4\u3cc\u3c3\u3ba\u3bf\u3bd and not \u3b4\u3cc\u3c3\u3ba\u3b5\u3bd. This assessment is congruent with the evidence from Eustathius. The dispute in the critical literature between the evaluation of \u3b4\u1ff6\u3ba\u3b5\u3bd as a variant or as an explanatory gloss is resolved in favour of the variant, by also considering the recurrent Didymean expression \u3ba\u3b1\u1f76 \u1f14\u3c3\u3c4\u3b9\u3bd \u3b5\u1f50\u3c6\u3c1\u3b1\u3b4\u3ad\u3c3\u3c4\u3b5\u3c1\u3bf\u3bd

    Towards a new critical edition of the scholia to the Iliad: a specimen

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    An on-going new critical edition is presented, designed to gather together for the first time all the scholia vetera to the Iliad transmitted by the manuscript tradition. A short introduction is followed by a sample of the new critical text (i.e. sch. in Iliadem A 6-11), compared to the corresponding part in Hartmut Erbse's edition

    Oceanographic and climatic consequences of the tectonic evolution of the southern scotia sea basins, Antarctica

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    The Scotia Sea is a complex geological area located in the Southern Ocean which evolution is closely linked to the opening of the Drake Passage. Structural highs of continental nature derived from the former continental bridge between South America and the Antarctic Peninsula surround the abyssal plains of the Scotia Sea, restricting small isolated sedimentary basins along its southern margin. Morpho-structural and seismo-stratigraphic analyses of multichannel seismic reflection profiles, and additional geophysical data available in the region, have been conducted, decoding regional and global implications of the basins' evolution. The main aim of this work is to describe the stratigraphic evolution of the southern Scotia Sea basins, from their opening in the back-arc tectonic context of the Scotia Sea, to the last oceanographic changes which have carried on global climatic implications. The evolution of the south Scotia Sea occurred through two major tectonic stages registered in the sedimentary record of the region: 1) the end of the subduction in the northwest part of the Weddell Sea during the early Miocene, which shortened the back-arc subduction trench generating a major change in the regional tectonic field that determined the evolution of the southern basins towards two different types of passive margins: magma-poor and magma-rich; and 2) the full development of the southern Scotia Sea basins during the middle Miocene, that led to the opening of deep oceanic gateways along the South Scotia Ridge. Interplay among tectonics, oceanography and climate is proposed to control the regional sedimentary stacking pattern, with coeval changes globally identified

    Galaxy and Mass Assembly (GAMA): Variation in Galaxy Structure Across the Green Valley

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    Using a sample of 472 local Universe (z < 0.06) galaxies in the stellar mass range 10.25 < log M*/MG < 10.75, we explore the variation in galaxy structure as a function of morphology and galaxy colour. Our sample of galaxies is sub-divided into red, green and blue colour groups and into elliptical and non-elliptical (disk-type) morphologies. Using KiDS and VIKING derived postage stamp images, a group of eight volunteers visually classified bars, rings, morphological lenses, tidal streams, shells and signs of merger activity for all systems. We find a significant surplus of rings (2.3σ) and lenses (2.9σ) in disk-type galaxies as they transition across the green valley. Combined, this implies a joint ring/lens green valley surplus significance of 3.3σ relative to equivalent disk-types within either the blue cloud or the red sequence. We recover a bar fraction of ∼ 44% which remains flat with colour, however, we find that the presence of a bar acts to modulate the incidence of rings and (to a lesser extent) lenses, with rings in barred disk-type galaxies more common by ∼ 20 − 30 percentage points relative to their unbarred counterparts, regardless of colour. Additionally, green valley disk-type galaxies with a bar exhibit a significant 3.0σ surplus of lenses relative to their blue/red analogues. The existence of such structures rules out violent transformative events as the primary end-of-life evolutionary mechanism, with a more passive scenario the favoured candidate for the majority of galaxies rapidly transitioning across the green valley. Key words: galaxies: elliptical and lenticular, cD – galaxies: spiral – galaxies: evo- lution – galaxies: star formation – galaxies: statistics – galaxies: structur

    Sensitivity projections for a dual-phase argon TPC optimized for light dark matter searches through the ionization channel

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    Dark matter lighter than 10  GeV/c2 encompasses a promising range of candidates. A conceptual design for a new detector, DarkSide-LowMass, is presented, based on the DarkSide-50 detector and progress toward DarkSide-20k, optimized for a low-threshold electron-counting measurement. Sensitivity to light dark matter is explored for various potential energy thresholds and background rates. These studies show that DarkSide-LowMass can achieve sensitivity to light dark matter down to the solar neutrino fog for GeV-scale masses and significant sensitivity down to 10  MeV/c2 considering the Migdal effect or interactions with electrons. Requirements for optimizing the detector’s sensitivity are explored, as are potential sensitivity gains from modeling and mitigating spurious electron backgrounds that may dominate the signal at the lowest energies

    Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial

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    Background Third-generation aromatase inhibitors are more effective than tamoxifen for preventing recurrence in postmenopausal women with hormone-receptor-positive invasive breast cancer. However, it is not known whether anastrozole is more effective than tamoxifen for women with hormone-receptor-positive ductal carcinoma in situ (DCIS). Here, we compare the efficacy of anastrozole with that of tamoxifen in postmenopausal women with hormone-receptor-positive DCIS. Methods In a double-blind, multicentre, randomised placebo-controlled trial, we recruited women who had been diagnosed with locally excised, hormone-receptor-positive DCIS. Eligible women were randomly assigned in a 1:1 ratio by central computer allocation to receive 1 mg oral anastrozole or 20 mg oral tamoxifen every day for 5 years. Randomisation was stratified by major centre or hub and was done in blocks (six, eight, or ten). All trial personnel, participants, and clinicians were masked to treatment allocation and only the trial statistician had access to treatment allocation. The primary endpoint was all recurrence, including recurrent DCIS and new contralateral tumours. All analyses were done on a modified intention-to-treat basis (in all women who were randomised and did not revoke consent for their data to be included) and proportional hazard models were used to compute hazard ratios and corresponding confidence intervals. This trial is registered at the ISRCTN registry, number ISRCTN37546358. Results Between March 3, 2003, and Feb 8, 2012, we enrolled 2980 postmenopausal women from 236 centres in 14 countries and randomly assigned them to receive anastrozole (1449 analysed) or tamoxifen (1489 analysed). Median follow-up was 7·2 years (IQR 5·6–8·9), and 144 breast cancer recurrences were recorded. We noted no statistically significant difference in overall recurrence (67 recurrences for anastrozole vs 77 for tamoxifen; HR 0·89 [95% CI 0·64–1·23]). The non-inferiority of anastrozole was established (upper 95% CI <1·25), but its superiority to tamoxifen was not (p=0·49). A total of 69 deaths were recorded (33 for anastrozole vs 36 for tamoxifen; HR 0·93 [95% CI 0·58–1·50], p=0·78), and no specific cause was more common in one group than the other. The number of women reporting any adverse event was similar between anastrozole (1323 women, 91%) and tamoxifen (1379 women, 93%); the side-effect profiles of the two drugs differed, with more fractures, musculoskeletal events, hypercholesterolaemia, and strokes with anastrozole and more muscle spasm, gynaecological cancers and symptoms, vasomotor symptoms, and deep vein thromboses with tamoxifen. Conclusions No clear efficacy differences were seen between the two treatments. Anastrozole offers another treatment option for postmenopausal women with hormone-receptor-positive DCIS, which may be be more appropriate for some women with contraindications for tamoxifen. Longer follow-up will be necessary to fully evaluate treatment differences

    Sensitivity projections for a dual-phase argon TPC optimized for light dark matter searches through the ionization channel

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    Sensitivity projections for a dual-phase argon TPC optimized for light dark matter searches through the ionization channel

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    Dark matter lighter than 10 GeV/c2^2 encompasses a promising range of candidates. A conceptual design for a new detector, DarkSide-LowMass, is presented, based on the DarkSide-50 detector and progress toward DarkSide-20k, optimized for a low-threshold electron-counting measurement. Sensitivity to light dark matter is explored for various potential energy thresholds and background rates. These studies show that DarkSide-LowMass can achieve sensitivity to light dark matter down to the solar neutrino floor for GeV-scale masses and significant sensitivity down to 10 MeV/c2^2 considering the Migdal effect or interactions with electrons. Requirements for optimizing the detector's sensitivity are explored, as are potential sensitivity gains from modeling and mitigating spurious electron backgrounds that may dominate the signal at the lowest energies

    Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): A double-blind, randomised controlled trial

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    Multi-messenger observations of a binary neutron star merger

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    On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
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