12 research outputs found

    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

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    Reliability estimation using an integrated support vector regression – variable neighborhood search model

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    As failure and reliability predictions play a significant role in production systems they have caught the attention of researchers. In this study, Support Vector Regression (SVR), which is known as a powerful neural network method, is developed as a way of forecasting reliability. Generally, SVR is applied in many research environments, and the results illustrate that SVR is a successful method in solving non-linear regression problems. However, SVR parameters tuning is a vital task for performing an accurate reliability estimation. We propose variable neighborhood search (VNS) for continuous space, including some simple but efficient shaking and local search as its main operators, to tune the SVR parameters and create a novel SVR-VNS hybrid system to improve the reliability of estimation accuracy. The proposed method is validated with a benchmark from the former literature and compared with conventional techniques, namely RBF (Gaussian), AR (autoregressive), MLP (logistic), MLP (Gaussian), and SVMG (SVM with genetic algorithm). The experimental results indicate that the proposed model has a superior performance for prediction reliability than other techniques

    Present status and future directions:Root resorption

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    Root resorption is the loss of dental hard tissue because of odontoclastic action. In permanent teeth, it is undesirable and pathological in nature. Root resorption may occur on the inner aspect of the root canal (internal root resorption) or on the outer aspect of the root (external root resorption). Regardless of its location, root resorption is irreversible, and may result in discomfort for the patient, requires management and/or, in some cases, results in the premature loss of the affected tooth. Root resorption is often challenging to accurately diagnose and manage. The aim of this narrative review is to present the relevant literature on the aetiology, pathogenesis, diagnosis and management, as well as discuss the future directions of diagnosis and management of root resorption

    Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food

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