Anytime Control using Input Sequences with Markovian Processor Availability

We study an anytime control algorithm for situations where the processing resources available for control are time-varying in an a priori unknown fashion. Thus, at times, processing resources are insufficient to calculate control inputs. To address this issue, the algorithm calculates sequences of tentative future control inputs whenever possible, which are then buffered for possible future use. We assume that the processor availability is correlated so that the number of control inputs calculated at any time step is described by a Markov chain. Using a Lyapunov function based approach we derive sufficient conditions for stochastic stability of the closed loop.Comment: IEEE Transactions on Automatic Control, to be publishe

Stochastic Stability of Event-triggered Anytime Control

We investigate control of a non-linear process when communication and processing capabilities are limited. The sensor communicates with a controller node through an erasure channel which introduces i.i.d. packet dropouts. Processor availability for control is random and, at times, insufficient to calculate plant inputs. To make efficient use of communication and processing resources, the sensor only transmits when the plant state lies outside a bounded target set. Control calculations are triggered by the received data. If a plant state measurement is successfully received and while the processor is available for control, the algorithm recursively calculates a sequence of tentative plant inputs, which are stored in a buffer for potential future use. This safeguards for time-steps when the processor is unavailable for control. We derive sufficient conditions on system parameters for stochastic stability of the closed loop and illustrate performance gains through numerical studies.Comment: IEEE Transactions on Automatic Control, under revie

A new and simple variable-angle accessory for infrared specular reflectance

A simple, low-cost accessory (patent pending) with only two flat mirrors and a new variable-angle mechanism has been developed for infrared specular reflectance measurements. The system allows the angles of incidence to be varied continuously from 15° (near normal incidence) to 85° (near grazing angle) without losing the alignment of the accessory. The reflectivity of boron nitride thin films deposited on metallic substrates has been measured at different angles of incidence to demonstrate the utility of this accessory

Cost-Effectiveness of Vaccination of Older Adults with an MF59®-Adjuvanted Quadrivalent Influenza Vaccine Compared to Standard-Dose and High-Dose Vaccines in Denmark, Norway, and Sweden

Individuals aged 65 years and above are at increased risk of complications and death from influenza compared with any other age group. Enhanced vaccines, as the MF59®-adjuvanted quadrivalent influenza vaccine (aQIV) and the high-dose quadrivalent influenza vaccine (HD-QIV), provide increased protection for older adults in comparison to the traditional standard-dose quadrivalent influenza vaccines (SD-QIV). This study aimed to assess the cost-effectiveness of aQIV compared to SD-QIV and HD-QIV in Denmark, Norway, and Sweden for adults aged ≥65 years. A static decision tree model was used to evaluate costs and outcomes of different vaccination strategies from healthcare payer and societal perspectives. This model projects that compared to SD-QIV, vaccination with aQIV could prevent a combined total of 18,772 symptomatic influenza infections, 925 hospitalizations, and 161 deaths in one influenza season across the three countries. From a healthcare payer perspective, the incremental costs per quality adjusted life year (QALY) gained with aQIV versus SD-QIV were EUR 10,170/QALY in Denmark, EUR 12,515/QALY in Norway, and EUR 9894/QALY in Sweden. The aQIV was cost saving compared with HD-QIV. This study found that introducing aQIV to the entire population aged ≥65 years may contribute to reducing the disease and economic burden associated with influenza in these countries.publishedVersio

Spatial Periodicity of Galaxy Number Counts, CMB Anisotropy, and SNIa Hubble Diagram Based on the Universe Accompanied by a Non-Minimally Coupled Scalar Field

We have succeeded in establishing a cosmological model with a non-minimally coupled scalar field $\phi$ that can account not only for the spatial periodicity or the {\it picket-fence structure} exhibited by the galaxy $N$-$z$ relation of the 2dF survey but also for the spatial power spectrum of the cosmic microwave background radiation (CMB) temperature anisotropy observed by the WMAP satellite. The Hubble diagram of our model also compares well with the observation of Type Ia supernovae. The scalar field of our model universe starts from an extremely small value at around the nucleosynthesis epoch, remains in that state for sufficiently long periods, allowing sufficient time for the CMB temperature anisotropy to form, and then starts to grow in magnitude at the redshift $z$ of $\sim 1$, followed by a damping oscillation which is required to reproduce the observed picket-fence structure of the $N$-$z$ relation. To realize such behavior of the scalar field, we have found it necessary to introduce a new form of potential $V(\phi)\propto \phi^2\exp(-q\phi^2)$, with $q$ being a constant. Through this parameter $q$, we can control the epoch at which the scalar field starts growing.Comment: 19 pages, 18 figures, Accepted for publication in Astrophysics & Space Scienc

Effect of the concentration of the nutrient solution on the nutrient content of chrysanthemum (Dendranthema grandiflorum (Ramat.)

Objective: Evaluate the nutrient concentration at the foliar level of chrysanthemums grown in tezontle sand using three concentrations of the Steiner Universal Nutrient Solution. Design/Methodology/Approach: A completely randomized design was used, each treatment represented a concentration of the nutrient solution and each concentration had 11 repetitions, the study variables were: foliar concentration of nutrients: N, P, K, Ca, Mg and S, plant height (AP), stem diameter (DT), number of leaves (NH), flower diameter (DF), fresh weight (PF) and dry weight (PS). Results: The results showed this order of extraction K>N>Ca>P>Mg>S, for all concentrations, the foliar N content was low in the three treatments (<3.35%), the P was found in high concentrations. (>0.63%), K was higher in the 100% concentration treatment, Mg (>0.44%) was in sufficient levels, in Ca the 100% concentration had greater absorption and finally the S content was only the adequate in the concentration of 100 %, in the morphological variables there were no significant differences. Limitations of the study/Implications: High temperatures helped the proliferation of pests; therefore, it would be good to have a better control of temperatures inside the greenhouse. Findings/Conclusions: Therefore, using different concentrations of the nutrient solution in chrysanthemums grown in tezontle sand affects the nutrient content at the foliar level but not necessarily its morphology

Opposite poles: A comparison between two Spanish regions in health-related quality of life, with implications for health policy

<p>Abstract</p> <p>Background</p> <p>Although health is one of the main determinants of the welfare of societies, few studies have evaluated health related quality of life in representative samples of the population of a region or a country. Our aim is to describe the health-related quality of life of the inhabitants of two quite different Spanish regions (Canary Islands and Catalonia) and to compare the prevalence of health problems between age-sex groups.</p> <p>Methods</p> <p>We use data obtained from the 2006 Health Survey of Catalonia and the 2004 Canary Islands Health Survey. With an ordinal composite variable measuring HRQOL we identify the association of characteristics of individuals with self-reported quality of life and test for differences between the regions.</p> <p>Results</p> <p>The prevalence of problems in the five EQ-5 D dimensions increases with age and is generally higher for women than for men. The dimension with the highest prevalence of problems is "anxiety/depression", and there is noteworthy the extent of discomfort and pain among Canary Island women. Education, especially among the elderly, has an important effect on health-related quality of life.</p> <p>Conclusions</p> <p>There are substantial structural and compositional differences between the two regions. Regional context is a significant factor, independent of the compositional differences, and the effects of context are manifest above all in women. The findings show the importance of disease prevention and the need for improving the educational level of the population in order to reduce health inequalities.</p

Small-scale spatial variation in infection risk shapes the evolution of a Borrelia resistance gene in wild rodents

This is the author accepted manuscript. The final version is available from Wiley via the DOI in this record.Spatial variation in pathogen-mediated selection is predicted to influence the evolutionary trajectory of host populations and lead to spatial variation in their immunogenetic composition. However, to date few studies have been able to directly link small-scale spatial variation in infection risk to host immune gene evolution in natural, non-human populations. Here we use a natural rodent-Borrelia system to test for associations between landscape-level spatial variation in Borrelia infection risk along replicated elevational gradients in the Swiss Alps and Toll-like receptor 2 (TLR2) evolution, a candidate gene for Borrelia resistance, across bank vole (Myodes glareolus) populations. We found that Borrelia infection risk (i.e. the product of Borrelia prevalence in questing ticks and the average tick load of voles at a sampling site) was spatially variable and significantly negatively associated with elevation. Across sampling sites, Borrelia prevalence in bank voles was significantly positively associated with Borrelia infection risk along the elevational clines. We observed a significant association between naturally occurring TLR2 polymorphisms in hosts and their Borrelia infection status. The TLR2 variant associated with a reduced likelihood of Borrelia infection was most common in rodent populations at lower elevations that face a high Borrelia infection risk, and its frequency changed in accordance with the change in Borrelia infection risk along the elevational clines. These results suggest that small-scale spatial variation in parasite-mediated selection affects the immunogenetic composition of natural host populations, providing a striking example that the microbial environment shapes the evolution of the host’s immune system in the wild.The study was financially supported by the Swiss National Science Foundation (PP00P3_128386 and PP00P3_157455), the University of Zurich Research Priority Program ‘Evolution in Action: from Genomes to Ecosystems’, the Faculty of Science of the University of Zurich, the Baugarten Stiftung, the Stiftung für wissenschaftliche Forschung an der Universität Zürich (STWF 17_027) and the Georges und Antoine Claraz-Schenkung

Modified Gravity and Cosmology

In this review we present a thoroughly comprehensive survey of recent work on modified theories of gravity and their cosmological consequences. Amongst other things, we cover General Relativity, Scalar-Tensor, Einstein-Aether, and Bimetric theories, as well as TeVeS, f(R), general higher-order theories, Horava-Lifschitz gravity, Galileons, Ghost Condensates, and models of extra dimensions including Kaluza-Klein, Randall-Sundrum, DGP, and higher co-dimension braneworlds. We also review attempts to construct a Parameterised Post-Friedmannian formalism, that can be used to constrain deviations from General Relativity in cosmology, and that is suitable for comparison with data on the largest scales. These subjects have been intensively studied over the past decade, largely motivated by rapid progress in the field of observational cosmology that now allows, for the first time, precision tests of fundamental physics on the scale of the observable Universe. The purpose of this review is to provide a reference tool for researchers and students in cosmology and gravitational physics, as well as a self-contained, comprehensive and up-to-date introduction to the subject as a whole.Comment: 312 pages, 15 figure