Guidance for Evidence-Informed Policies about Health Systems: Linking Guidance Development to Policy Development

In the second paper in a three-part series on health systems guidance, John Lavis and colleagues explore the challenge of linking guidance development and policy development at global and national levels

Improving bank erosion modelling at catchment scale by incorporating temporal and spatial variability

Bank erosion can contribute a significant portion of the sediment budget within temperate catchments, yet few catchment scale models include an explicit representation of bank erosion processes. Furthermore, representation is often simplistic resulting in an inability to capture realistic spatial and temporal variability in simulated bank erosion. In this study, the sediment component of the catchment scale model SHETRAN is developed to incorporate key factors influencing the spatio-temporal rate of bank erosion, due to the effects of channel sinuosity and channel bank vegetation. The model is applied to the Eden catchment, north-west England, and validated using data derived from a GIS methodology. The developed model simulates magnitudes of total catchment annual bank erosion (617 - 4063 t yr-1) within the range of observed values (211 - 4426 t yr-1). Additionally the model provides both greater inter-annual and spatial variability of bank eroded sediment generation when compared with the basic model, and indicates a potential 61% increase of bank eroded sediment as a result of temporal flood clustering. The approach developed within this study can be used within a number of distributed hydrologic models and has general applicability to temperate catchments, yet further development of model representation of bank erosion processes is required

Personality traits and mental disorders

Peer reviewe

The organisation of TB nursing work in primary health clinics in Cape Town, South Africa

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Communication around HPV vaccination for adolescents in low- and middle-income countries: a systematic scoping overview of systematic reviews

Abstract Background: Human papillomavirus (HPV) infection causes cervical cancer. More than 80% of those diagnosed with cervical cancer live in low- and middle-income countries (LMICs). The World Health Organization recommends vaccination as a public health measure against cervical cancer. Communication interventions are able to change how people think about vaccination and are thus instrumental in addressing vaccine hesitancy. Our aim was to provide a broad scoping overview of the available evidence on communication with adolescents, parents, and other stakeholders around HPV vaccination for adolescents, with a specific focus on LMICs. Methods: We conducted a systematic scoping overview of systematic reviews addressing a range of questions regarding communication around HPV vaccination. We considered reviews published between 2007 and 2018 focusing on communication around HPV vaccination and that searched for qualitative or quantitative studies for inclusion. We searched the Epistemonikos database which includes reviews from multiple electronic databases. Two overview authors screened titles and abstracts and examined potentially eligible reviews in full text. Data extraction was performed by one overview author and verified by a second. We assessed the reliability of the included reviews using an adapted version of AMSTAR 2. Results: We included twelve reviews in our overview. Four reviews assessed the effectiveness of communication interventions. These interventions intended to inform or educate about HPV and HPV vaccination, such as videos and fact sheets, or to remind or recall, such as text message reminders. Eight reviews assessed factors associated with HPV vaccination uptake, including communication-related factors such as whether the vaccine was recommended by a physician and people’s knowledge regarding the vaccine. Nine reviews searched for studies from LMICs, but most found only a small number of studies from these countries. Conclusions: The small number of studies identified from LMICs is of concern as these countries face the largest burden of disease related to HPV. This scoping overview also found and excluded a number of reviews because of important methodological limitations, highlighting the need for future reviews to use appropriate methods. The overview indicates areas in which further primary studies are needed on HPV vaccination communication in LMICs. Systematic review registration: Open Science Framework https://osf.io/agzb4/ Keywords: HPV, Human papillomavirus, Vaccine, Communication, Intervention, Adolescents, Low-income countries, Middle-income countries, Low- and middle-income countries, Systematic scoping overview of systematic review

Healthcare workers’ perceptions and experiences of communicating with people over 50 about vaccination: a qualitative evidence synthesis (Protocol)

This is a protocol for a Cochrane Review (qualitative). The objectives are as follows: To explore healthcare workers' perceptions and experiences of communication between themselves and older adults about vaccination