470 research outputs found
Precise measurement of the W-boson mass with the CDF II detector
- Author
- Aaltonen T.
- Abbaneo D
- Adzic P
- Aguilar-Benitez M
- Ahmad M
- Ahmed I
- Albajar C
- Allfrey P
- Almeida N
- Alvarez Gonzalez B.
- Amerio S.
- Amidei D.
- Anastassov A.
- Andreev V
- Andreev Y
- Annovi A.
- Antos J.
- Apollinari G.
- Appel J. A.
- Arce P
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- Asaadi J.
- Asghar MI
- Ashmanskas W.
- Auerbach B.
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- Azarkin M
- Azfar F.
- Azhgirey I
- Badgett W.
- Bae T.
- Baillon P
- Ball AH
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- Barney D
- Barria P.
- Bartos P.
- Battilana C
- Bauce M.
- Bedeschi F.
- Bedoya CF
- Beecher D.
- Behari S.
- Bell AJ
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- Bellinger J.
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- Benedetti D
- Benjamin D.
- Beretvas A.
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- Bialas W
- Bilinskas MJ
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- Bisello D.
- Bitioukov S
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- Bland K. R.
- Bloch P
- Blumenfeld B.
- Bocci A
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- Bodek A.
- Bolognesi S
- Bondar N
- Boos E
- Bortoletto D.
- Boudreau J.
- Boveia A.
- Breuker H
- Brigliadori L.
- Bromberg C.
- Brona G
- Brucken E.
- Budagov J.
- Budd H. S.
- Bunin P
- Bunkowski K
- Burelo ED
- Burkett K.
- Busetto G.
- Bussey P.
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- Caballero IG
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- Calamba A.
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- Calvo E
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- Innocente V
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- Kirakosyan M
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- Kodolova O
- Kondo K.
- Konecki M
- Kong D. J.
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- Konstantinov D
- Korablev A
- Kossov M
- Kotwal A. V.
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- Krasnikov N
- Kreps M.
- Krofcheck D
- Krokhotin A
- Krolikowski J
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- Krop D.
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- Kruse M.
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- Kuhr T.
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- Levchenko P
- Lewis J. D.
- Limosani A.
- Lin C. -J.
- Linares EC
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- Lipeles E.
- Lister A.
- Litvintsev D. O.
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- Palencia E.
- Palichik V
- Papadimitriou V.
- Paramonov A. A.
- Pardo PL
- Pardos CD
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- Parracho PGF
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- Patrick J.
- Pauletta G.
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- Pellett D. E.
- Penzo A.
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- Piacentino G.
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- Weinberger M.
- Wester W. C. III
- Wester W. C. III
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- Winer B. L.
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- Wittich P.
- Wohri HK
- Wolbers S.
- Wolbers S.
- Wolfe H.
- Wolfe H.
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- Wright T.
- Wrochna G
- Wu X.
- Wu X.
- Wu Z.
- Wu Z.
- Yamamoto K.
- Yamamoto K.
- Yamaoka J.
- Yamato D.
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- Yang T.
- Yang U. K.
- Yang U. K.
- Yang Y. C.
- Yang Y. C.
- Yao W. -M.
- Yao W. -M.
- Yeh G. P.
- Yeh G. P.
- Yi K.
- Yi K.
- Yoh J.
- Yoh J.
- Yorita K.
- Yorita K.
- Yoshida T.
- Yoshida T.
- Yu G. B.
- Yu G. B.
- Yu I
- Yu I.
- Yu I.
- Yu S. S.
- Yu S. S.
- Yun J. C.
- Yun J. C.
- Zalewski R
- Zanetti A.
- Zanetti A.
- Zarubin A
- Zeng Y.
- Zeng Y.
- Zhokin A
- Zhou C.
- Zucchelli S..
- Zucchelli S..ng S
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
We have measured the W-boson mass MW using data corresponding to 2.2/fb of
integrated luminosity collected in proton-antiproton collisions at 1.96 TeV
with the CDF II detector at the Fermilab Tevatron collider. Samples consisting
of 470126 W->enu candidates and 624708 W->munu candidates yield the measurement
MW = 80387 +- 12 (stat) +- 15 (syst) = 80387 +- 19 MeV. This is the most
precise measurement of the W-boson mass to date and significantly exceeds the
precision of all previous measurements combined
Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdel Khalek S
- Abdelalim AA
- Abdinov O
- Aben R
- Abi B
- Abolins M
- Abouzeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Agustoni M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akesson TP
- Akimoto G
- Akimov AV
- Alam MA
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BM
- Allison LJ
- Allport PP
- Allwood-Spiers SE
- Almond J
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- Amako K
- Amelung C
- Ammosov VV
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- Anastopoulos C
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- Andari N
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- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Anduaga XS
- Angelidakis S
- Anger P
- Angerami A
- Anghinolfi F
- Anisenkov A
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- Annovi A
- Antonaki A
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- ATLAS Collaboration The
- Auerbach B
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- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02 TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1 μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos2Δϕ modulation for all ΣETPb ranges and particle pT
Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector
- Author
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- Galea C
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- Galhardo B
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- Gallas EJ
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- Gallo V
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- Gandrajula RP
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- Gao J
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- Gaob J
- Garberson F
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- Garcia Navarro JE
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- Garcia BRM
- Garcia C
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- Garcia-Sciveres M
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- Gardner RW
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- Garelli N
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- Garonne V
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- Garrido MDMC
- Gatti C
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- Gaudio G
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- Gaur B
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- Gauzzi P
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- Gavrilenko IL
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- Gaycken G
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- Gazis EN
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- Ge P
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- Gecse Z
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- Gee CNP
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- Geerts DAA
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- Geich-Gimbel C
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- Gellerstedt K
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- Gemme C
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- Gemmell A
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- Genest MH
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- Gentile S
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- George M
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- George S
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- Gerbaudo D
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- Gershon A
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- Ghazlane H
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- Ghodbane N
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- Giacobbe B
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- Giannetti P
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- Gianotti F
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- Gibbard B
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- Gibson SM
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- Gilchriese M
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- Gillam TPS
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- Gillberg D
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- Gillman AR
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- Gingrich M
- Giokaris N
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- Giordani MP
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- Giordano R
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- Giuliani C
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- Gorbounov PA
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- Gorini B
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- Goshaw AT
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- Zhemchugov A
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- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
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- Zobernig G
- Zoccoli A
- Zurzolo G
- Zutshi V
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2014
- Field of study
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}andcorrespondtoanintegratedluminosityof4.6\;{\rm f}{{{\rm b}}^{-1}}.ThemeasurementisperformedbyreconstructingtheboostedWorZbosonsinsinglejets.ThereconstructedjetmassisusedtoidentifytheWandZbosons,andajetsubstructuremethodbasedonenergyclusterinformationinthejetcentre−of−massframeisusedtosuppressthelargemulti−jetbackground.Thecross−sectionforeventswithahadronicallydecayingWorZboson,withtransversemomentum{{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}andpseudorapidity|\eta |\lt 1.9,ismeasuredtobe{{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques
Search for direct pair production of the top squark in all-hadronic final states in proton-proton collisions at s√=8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdinov O
- Aben R
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- Abolins M
- AbouZeid OS
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- Agustoni M
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- Akesson TPA
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- Zhemchugov A
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- Zobernig G
- Zoccoli A
- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1fb−1 of proton–proton collision data at √s = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via t˜→tχ˜01 or t˜→ bχ˜±1 →bW(∗)χ˜01 , where χ˜01 (χ˜±1 ) denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final state in events with four or more jets and large missing transverse momentum. No significant excess over the Standard Model background prediction is observed, and exclusion limits are reported in terms of the top squark and neutralino masses and as a function of the branching fraction of t˜ → tχ˜01 . For a branching fraction of 100%, top squark masses in the range 270–645 GeV are excluded for χ˜01 masses below 30 GeV. For a branching fraction of 50% to either t˜ → tχ˜01 or t˜ → bχ˜±1 , and assuming the χ˜±1 mass to be twice the χ˜01 mass, top squark masses in the range 250–550 GeV are excluded for χ˜01 masses below 60 GeV
Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at √s=8TeV
- Author
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- Rurikova Z
- Rusakovich NA
- Ruschke A
- Rutherfoord JP
- Ruthmann N
- Ryabov YF
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- Sabato G
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- Sadrozinski HF-W
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- Salamanna G
- Salamon A
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- Salvucci A
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- Schnellbach YJ
- Schnoor U
- Schoeffel L
- Schoening A
- Schoenrock BD
- Schorlemmer ALS
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- Schouten D
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- Schroeder TV
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- Schultz-Coulon H-C
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- Seliverstov DM
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- Shan LY
- Shang R
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- Shehu CY
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- Shimmin CO
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- Slavicek T
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- Smizanska M
- Smolek K
- Snesarev AA
- Snidero G
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- Sundermann JE
- Suruliz K
- Susinno G
- Sutton MR
- Suzuki Y
- Svatos M
- Swedish S
- Swiatlowski M
- Sykora I
- Sykora T
- Ta D
- Taccini C
- Tackmann K
- Taenzer J
- Taffard A
- Tafirout R
- Taiblum N
- Takai H
- Takashima R
- Takeda H
- Takeshita T
- Takubo Y
- Talby M
- Talyshev AA
- Tam JYC
- Tan KG
- Tanaka J
- Tanaka R
- Tanaka S
- Tanaka S
- Tanasijczuk AJ
- Tannenwald BB
- Tannoury N
- Tapprogge S
- Tarem S
- Tarrade F
- Tartarelli GF
- Tas P
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- Tayalati Y
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- Taylor GN
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- Ten Kate H
- Teng PK
- Teoh JJ
- Terada S
- Terashi K
- Terron J
- Terzo S
- Testa M
- Teuscher RJ
- Therhaag J
- Theveneaux-Pelzer T
- Thomas JP
- Thomas-Wilsker J
- Thompson AS
- Thompson EN
- Thompson PD
- Thompson PD
- Thompson RJ
- Thomsen LA
- Thomson E
- Thomson M
- Thong WM
- Thun RP
- Tian F
- Tibbetts MJ
- Tikhomirov VO
- Tikhonov YA
- Timoshenko S
- Tiouchichine E
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- Tisserant S
- Todorov T
- Todorova-Nova S
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- Tojo J
- Tokar S
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- Tollefson K
- Tolley E
- Tomlinson L
- Tomoto M
- Tompkins L
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- Topilin ND
- Toro RC
- Torregrosa EF
- Torrence E
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- Torro Pastor E
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- Touchard F
- Tovey DR
- Tran HL
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- Tremblet L
- Tricoli A
- Trigger IM
- Trincaz-Duvoid S
- Tripiana MF
- Trischuk W
- Trocme B
- Troncon C
- Trottier-McDonald M
- Trovatelli M
- True P
- Trzebinski M
- Trzupek A
- Tsarouchas C
- Tseng JC-L
- Tsiareshka PV
- Tsionou D
- Tsipolitis G
- Tsirintanis N
- Tsiskaridze S
- Tsiskaridze V
- Tskhadadze EG
- Tsukerman I
- Tsulaia V
- Tsuno S
- Tsybychev D
- Tudorache A
- Tudorache V
- Tuna AN
- Tupputi SA
- Turchikhin S
- Turecek D
- Turra R
- Tuts PM
- Tykhonov A
- Tylmad M
- Tyndel M
- Uchida K
- Ueda I
- Ueno R
- Ughetto M
- Ugland M
- Uhlenbrock M
- Ukegawa F
- Unal G
- Undrus A
- Unel G
- Ungaro FC
- Unno Y
- Unverdorben C
- Urbaniec D
- Urquijo P
- Usai G
- Usanova A
- Vacavant L
- Vacek V
- Vachon B
- Valencic N
- Valentinetti S
- Valero A
- Valery L
- Valkar S
- Vallecorsa S
- Van Den Wollenberg W
- Van Der Deijl PC
- van der Geer R
- van der Graaf H
- Van Der Leeuw R
- van der Ster D
- Van Eldik N
- Van Gemmeren P
- van Huysduynen LH
- Van Nieuwkoop J
- van Vulpen I
- Van Woerden MC
- Vanadia M
- Vandelli W
- Vanguri R
- Vaniachine A
- Vankov P
- Vannucci F
- Vaque FV
- Vardanyan G
- Vari R
- Varnes EW
- Varol T
- Varouchas D
- Vartapetian A
- Varvell KE
- Vazeille F
- Vazquez JGP
- Veatch J
- Veloso F
- Velz T
- Veneziano S
- Ventura A
- Ventura D
- Venturi M
- Venturi N
- Venturini A
- Vercesi V
- Verducci M
- Verkerke W
- Vermeulen JC
- Verzini MJA
- Vest A
- Vetterli MC
- Viazlo O
- Vichou I
- Vickey T
- Viehhauser GHA
- Viel S
- Vigne R
- Villa M
- Vilucchi E
- Vincter MG
- Vinogradov VB
- Virzi J
- Vivarelli I
- Vlachos S
- Vladoiu D
- Vlasak M
- Vogel A
- Vokac P
- Volpi G
- Volpi M
- von der Schmitt H
- von Radziewski H
- von Toerne E
- Vorobel V
- Vorobev K
- Vos M
- Voss R
- Vossebeld JH
- Vranjes N
- Vrba V
- Vreeswijk M
- Vuanh T
- Vuillermet R
- Vukotic I
- Vykydal Z
- Wagner P
- Wagner W
- Wahlberg H
- Wahrmund S
- Wakabayashi J
- Walder J
- Walker R
- Walkowiak W
- Wall R
- Waller P
- Walls FMG
- Walsh B
- Wang C
- Wang C
- Wang F
- Wang H
- Wang H
- Wang J
- Wang J
- Wang K
- Wang R
- Wang SM
- Wang T
- Wang X
- Wanotayaroj C
- Warburton A
- Ward CP
- Wardrope DR
- Warsinsky M
- Washbrook A
- Wasicki C
- Watkins PM
- Watson AT
- Watson IJ
- Watson MF
- Watts G
- Watts S
- Waugh BM
- Webb S
- Weber MS
- Weber SW
- Webster JS
- Weidberg AR
- Weigell P
- Weinert B
- Weingarten J
- Weiser C
- Weits H
- Wells PS
- Wemans ADV
- Wenaus T
- Wendland D
- Weng Z
- Wengler T
- Wenig S
- Wermes N
- Werner M
- Werner P
- Wessels M
- Wetter J
- Whalen K
- White A
- White MJ
- White R
- White S
- Whiteson D
- Wicke D
- Wickens FJ
- Wiedenmann W
- Wielers M
- Wienemann P
- Wiglesworth C
- Wiik-Fuchs LAM
- Wijeratne PA
- Wildauer A
- Wildt MA
- Wilkens HG
- Will JZ
- Williams HH
- Williams S
- Willis C
- Willocq S
- Wilson A
- Wilson JA
- Wingerter-Seez I
- Winklmeier F
- Winter BT
- Wittgen M
- Wittig T
- Wittkowski J
- Wollstadt SJ
- Wolter MW
- Wolters H
- Wong KHY
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wozniak KW
- Wright M
- Wu M
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wyatt TR
- Wynne BM
- Xella S
- Xiao M
- Xu D
- Xu L
- Yabsley B
- Yacoob S
- Yakabe R
- Yamada M
- Yamaguchi H
- Yamaguchi Y
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamauchi K
- Yamazaki Y
- Yan Z
- Yang H
- Yang H
- Yang UK
- Yang Y
- Yanush S
- Yao L
- Yao W-M
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yeletskikh I
- Yen AL
- Yildirim E
- Yildiz HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJS
- Youssef S
- Yu DR
- Yu J
- Yu J
- Yu JM
- Yuan L
- Yurkewicz A
- Yusuff I
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zaman A
- Zambito S
- Zanello L
- Zanzi D
- Zeitnitz C
- Zeman M
- Zemla A
- Zengel K
- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou L
- Zhou N
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fb−1of data collected in proton–proton collisions at √s=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV
Vacationers Happier, but Most not Happier After a Holiday
- Author
- A Milman
- A Terraciano
- Ad J. Vingerhoets
- AF Stokes
- AJJM Vingerhoets
- BA Brown
- BB Gump
- C Ryan
- C Ryan
- D Bell
- D Boorstin
- D Gilbert
- D Gilbert
- D MacCannell
- D Watson
- DG Myers
- E Diener
- E Diener
- E Gross
- FB Bryant
- G Easterbrook
- G Miller
- G Strauss-Blasche
- GL Heck Van
- GL Parrinello
- H Brandstätter
- J Bloom De
- J Gnoth
- J Schor
- J Schor
- JD Neal
- JD Neal
- Jeroen Nawijn
- JP Gustavsson
- JW Lounsbury
- LL Hoopes
- M Clawson
- M Hickson III
- M Kostecki
- M Morgan
- M Opperman
- M Westman
- M Westman
- MA Tilburg Van
- Miquelle A. Marchand
- N Uriely
- PL Pearce
- PT Costa
- R Veenhoven
- R Veenhoven
- R Veenhoven
- R Veenhoven
- RA Cummins
- RC Prentice
- RR McCrae
- RR McCrae
- Ruut Veenhoven
- RW Butler
- S Kemp
- S Larsen
- S Larsen
- S Lash
- S McCabe
- SE Hampson
- TR Mitchell
- UNWTO
- W Pavot
- WJ Kop
- Publication venue
- Springer Netherlands
- Publication date
- 01/01/2010
- Field of study
The aim of this study was to obtain a greater insight into the association between vacations and happiness. We examined whether vacationers differ in happiness, compared to those not going on holiday, and if a holiday trip boosts post-trip happiness. These questions were addressed in a pre-test/post-test design study among 1,530 Dutch individuals. 974 vacationers answered questions about their happiness before and after a holiday trip. Vacationers reported a higher degree of pre-trip happiness, compared to non-vacationers, possibly because they are anticipating their holiday. Only a very relaxed holiday trip boosts vacationers’ happiness further after return. Generally, there is no difference between vacationers’ and non-vacationers’ post-trip happiness. The findings are explained in the light of set-point theory, need theory and comparison theory
Spatial Analyses of Benthic Habitats to Define Coral Reef Ecosystem Regions and Potential Biogeographic Boundaries along a Latitudinal Gradient
- Author
- A Thorhaug
- AE Lugo
- AY Cantillo
- B Riegl
- B Vargas-Ángel
- B Vargas-Ángel
- BH Lidz
- BK Walker
- BK Walker
- BK Walker
- BK Walker
- BM Costa
- BP Hayden
- Brian K. Walker
- C Parmesan
- CJ Dawes
- CW Finkl
- D Lirman
- DF Austin
- DR Calder
- DS Gilliam
- E Macpherson
- EC Pielou
- EH Rapoport
- F Dahdouh-Guebas
- G Foster
- GC Stevens
- GL Voss
- H Yamano
- HJ Humm
- HT Odum
- J Brock
- J Kleypas
- JC Briggs
- JC Brock
- JEN Veron
- JJ Wiens
- JW Valentine
- K Banks
- KC Lindeman
- KG Ashton
- KL Heck Jr
- KW Banks
- L Herren
- LKB Jordan
- LL Richardson
- LW Hutchins
- MD Gilmore
- MR Willig
- MS Kendall
- Philippe Archambault
- PJ Mumby
- R Chardon
- R France
- R Grober-Dunsmore
- RA Locarnini
- RE Chardon
- RE Dodge
- RG Lighty
- RH Fraser
- RM Baron
- RN Ginsburg
- RP Moyer
- SA Lourie
- SJ Pittman
- SL Chown
- TR Karl
- VD Engle
- W Kiessling
- WF Precht
- Publication venue
- Public Library of Science
- Publication date
- 19/01/2012
- Field of study
Marine organism diversity typically attenuates latitudinally from tropical to colder climate regimes. Since the distribution of many marine species relates to certain habitats and depth regimes, mapping data provide valuable information in the absence of detailed ecological data that can be used to identify and spatially quantify smaller scale (10 s km) coral reef ecosystem regions and potential physical biogeographic barriers. This study focused on the southeast Florida coast due to a recognized, but understudied, tropical to subtropical biogeographic gradient. GIS spatial analyses were conducted on recent, accurate, shallow-water (0–30 m) benthic habitat maps to identify and quantify specific regions along the coast that were statistically distinct in the number and amount of major benthic habitat types. Habitat type and width were measured for 209 evenly-spaced cross-shelf transects. Evaluation of groupings from a cluster analysis at 75% similarity yielded five distinct regions. The number of benthic habitats and their area, width, distance from shore, distance from each other, and LIDAR depths were calculated in GIS and examined to determine regional statistical differences. The number of benthic habitats decreased with increasing latitude from 9 in the south to 4 in the north and many of the habitat metrics statistically differed between regions. Three potential biogeographic barriers were found at the Boca, Hillsboro, and Biscayne boundaries, where specific shallow-water habitats were absent further north; Middle Reef, Inner Reef, and oceanic seagrass beds respectively. The Bahamas Fault Zone boundary was also noted where changes in coastal morphologies occurred that could relate to subtle ecological changes. The analyses defined regions on a smaller scale more appropriate to regional management decisions, hence strengthening marine conservation planning with an objective, scientific foundation for decision making. They provide a framework for similar regional analyses elsewhere
Effects of caffeine on time to exhaustion in exercise performed below and above the anaerobic threshold
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Chemotherapy-Induced Late Transgenerational Effects in Mice
- Author
- A Albini
- A Dalvi
- A Jemal
- A Jemal
- A Jurisicova
- A Nagy
- AB Mariotto
- AJ Wyrobek
- AY Ting
- B Chabi
- Brenda Marrero-Rosado
- CD Aluise
- CE Jansen
- D Montaigne
- D Ren
- DJ White
- DM Green
- DM Green
- DM Green
- E Fox
- Eun A. Chang
- F Paris
- FM Safdie
- G Hofhaus
- GI Perez
- GI Perez
- GI Perez
- GI Perez
- GI Perez
- GI Perez
- GI Perez
- Gloria I. Perez
- GM Cooper
- HC Lai
- HO Critchley
- HO Critchley
- Hongbing Wang
- I Ben-Aharon
- J Johnson
- J Kasapovic
- JB Bishop
- JB Bishop
- JC St John
- JF Winther
- JH Falkenberg
- JM Trasler
- Jose B. Cibelli
- K Nakayama
- K Oktay
- K Rowan
- KE Heck
- KL Witt
- L Raffaghello
- LB Signorello
- LB Signorello
- LE Bath
- LK McLoon
- LL Kujjo
- LM Madanat-Harjuoja
- Loro L. Kujjo
- LR Schover
- LR Schover
- M Stovall
- M Tachibana
- MA Katoh
- MC Grady
- MM Langenhuijsen
- N Patel
- N Salooja
- NA Listed
- P Jacquet
- P Stavem
- PF Chinnery
- PF Chinnery
- RA Veitia
- Ricardo J. G. Pereira
- S Nagar
- Satyaki Sengupta
- Shilpa Dhar
- Siyaram Pandey
- T Karl
- T Matikainen
- TR Gregory
- VT DeVita Jr
- Y Morita
- Y Takai
- Publication venue
- Public Library of Science
- Publication date
- 17/03/2011
- Field of study
To our knowledge, there is no report on long-term reproductive and developmental side effects in the offspring of mothers treated with a widely used chemotherapeutic drug such as doxorubicin (DXR), and neither is there information on transmission of any detrimental effects to several filial generations. Therefore, the purpose of the present paper was to examine the long-term effects of a single intraperitoneal injection of DXR on the reproductive and behavioral performance of adult female mice and their progeny. C57BL/6 female mice (generation zero; G0) were treated with either a single intraperitoneal injection of DXR (G0-DXR) or saline (G0-CON). Data were collected on multiple reproductive parameters and behavioral analysis for anxiety, despair and depression. In addition, the reproductive capacity and health of the subsequent six generations were evaluated. G0-DXR females developed despair-like behaviors; delivery complications; decreased primordial follicle pool; and early lost of reproductive capacity. Surprisingly, the DXR-induced effects in oocytes were transmitted transgenerationally; the most striking effects being observed in G4 and G6, constituting: increased rates of neonatal death; physical malformations; chromosomal abnormalities (particularly deletions on chromosome 10); and death of mothers due to delivery complications. None of these effects were seen in control females of the same generations. Long-term effects of DXR in female mice and their offspring can be attributed to genetic alterations or cell-killing events in oocytes or, presumably, to toxicosis in non-ovarian tissues. Results from the rodent model emphasize the need for retrospective and long-term prospective studies of survivors of cancer treatment and their offspring
Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids
- Author
- A Groyer
- A Kleiman
- A McMaster
- Adali Pecci
- Adriana S. Veleiro
- AK Nagaich
- AR Clark
- AS Veleiro
- AS Veleiro
- AS Veleiro
- B Kauppi
- B Kim
- B van Steensel
- BM Necela
- C Iavarone
- C Stahn
- Cameron Neylon
- CL Smith
- D Walker
- DA Pearlman
- Diego M. Presman
- EC Guido
- G Burton
- G Chalepakis
- GA Schoch
- Gerardo Burton
- GL Hager
- GP Vicent
- H Gronemeyer
- H Htun
- H Htun
- H Ogawa
- HC Raaijmakers
- HJC Berendsen
- HM Reichardt
- I Segard-Maurel
- IM Nojek
- J Drouin
- JG Savory
- JJ Kohler
- JP Aumais
- JS Lai
- K Biggadike
- K Dahlman-Wright
- K Dahlman-Wright
- K Suino-Powell
- KB Horwitz
- KL Gross
- KP Madauss
- L Frego
- Lautaro D. Alvarez
- LD Alvarez
- LD Alvarez
- LL Molinero
- M Adams
- M Lippman
- M Schulz
- M Truss
- MA Costas
- MA Digman
- MA Digman
- Marcelo A. Martí
- MD Galigniana
- Michelle A. Digman
- MJ Marinissen
- MJ Schaaf
- N Guex
- NC Andrews
- NZ Lu
- O Kassel
- O Wrange
- P Dewint
- P Eriksson
- PH Olivier Kassel
- PJ Godowski
- Q Wang
- R Bhandare
- R Kumar
- R Newton
- RB Dalal
- RC Gaussian 03
- RK Bledsoe
- S Heck
- S Mikuni
- S Pandit
- S Roberson
- S Rusconi
- S van der Laan
- Silvina Eduardo
- SY Tsai
- T Chen
- T Willmann
- TC Voss
- TE Cheatham III
- Valeria Levi
- W Cairns
- W Humphrey
- W Liu
- X Li
- Y Chen
- Y He
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Background: The glucocorticoid receptor (GR) is a transcription factor that regulates gene expression in a ligand-dependent fashion. This modular protein is one of the major pharmacological targets due to its involvement in both cause and treatment of many human diseases. Intense efforts have been made to get information about the molecular basis of GR activity. Methodology/Principal Findings: Here, the behavior of four GR-ligand complexes with different glucocorticoid and antiglucocorticoid properties were evaluated. The ability of GR-ligand complexes to oligomerize in vivo was analyzed by performing the novel Number and Brightness assay. Results showed that most of GR molecules form homodimers inside the nucleus upon ligand binding. Additionally, in vitro GR-DNA binding analyses suggest that ligand structure modulates GRDNA interaction dynamics rather than the receptor's ability to bind DNA. On the other hand, by coimmunoprecipitation studies we evaluated the in vivo interaction between the transcriptional intermediary factor 2 (TIF2) coactivator and different GR-ligand complexes. No correlation was found between GR intranuclear distribution, cofactor recruitment and the homodimerization process. Finally, Molecular determinants that support the observed experimental GR LBD-ligand/TIF2 interaction were found by Molecular Dynamics simulation. Conclusions/Significance: The data presented here sustain the idea that in vivo GR homodimerization inside the nucleus can be achieved in a DNA-independent fashion, without ruling out a dependent pathway as well. Moreover, since at least one GR-ligand complex is able to induce homodimer formation while preventing TIF2 coactivator interaction, results suggest that these two events might be independent from each other. Finally, 21-hydroxy-6,19-epoxyprogesterone arises as a selective glucocorticoid with potential pharmacological interest. Taking into account that GR homodimerization and cofactor recruitment are considered essential steps in the receptor activation pathway, results presented here contribute to understand how specific ligands influence GR behavior. © 2010 Presman et al.Fil:Presman, D.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Alvarez, L.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Levi, V. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Martí, M.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Veleiro, A.S. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Burton, G. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Pecci, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
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