Fatigue Analysis of High Performance Cement Concrete for Pavements Using the Probabilistic Approach

Cement concrete pavements are designed for flexural fatigue loading due to traffic. Due to its numerous advantages high performance cement concrete is finding it’s way in pavement construction. This paper investigates the fatigue strength of High Performance Cement Concretes subjected to flexural loading. Fatigue studies are conducted on these concretes to obtain the fatigue lives at various stress levels. Static flexural strength tests are conducted to determine the static failure loads on prism specimen. From the experimental studies carried out, the number of load repetitions to failure on the concretes under study is determined for three stress ratios. From the data obtained S-N curves are developed using linear regression models considering log normal distribution as is being presently adopted. Recent literature shows that weibull distribution is found to have more convincing physical features than the lognormal distribution to describe the fatigue behavior o concrete. To incorporate the probability of failure, weibull distribution is considered and Pf-S-N diagram are developed. It is observed that addition of fly ash and silica fume improves the fatigue performance of concrete by48% and 83% at a stress level of 0.75

Bioactive Components of Magical Velvet Beans

The plant Mucuna is an annual climbing shrub with long vines that can reach over fifteen meters in length. About 100–150 Mucuna species are found in the tropic and subtropic regions of both hemispheres of the earth. The genus Mucuna belongs to the family Leguminosae. It is commonly known as Kewanch, velvet bean, cowhage and kappikachhu and is found widely in India as a hardy, herbaceous, vigorous, twining annual plant. The size and dimension of the Mucuna seeds, pods, platelets and leaves change from species to species. The hair present on pods is anthelmintic, which causes itching. People are seeking great attention towards Mucuna due to its several medicinal properties, including L-DOPA (L-3, 4-dihydroxyphenylalanine) along with supplementary antioxidants that are used for treating Parkinson’s disease and many neurodegenerative diseases. Thus it is being used in about 200 medicinal formulations. The current chapter outlines the work that determines the influence of different nutritional, anti-nutritional and medicinal values and bioactive agents from different parts of the Mucuna species present in India and its importance in medicine

Isolation and characterization of Plasmid DNA from clinically isolated E.coli strain at Pravara rural hospital, Loni, India

Abstract Urinary Tract Infection (UTI) is one of the most common infectious diseases and people of all age-groups and geographical locations are affected. Multiple resistance to antimicrobials drugs arising in Escherichia coli isolate may complicate therapeutic management of UTI. The present study aimed to isolate and characterize plasmid DNA from Clinical isolated E. coli. Biochemical tests confirm that the hospital isolate is E.coli and antibiotic susceptibility test results shows that it is MDR strain. Molecular techniques such as plasmid DNA isolation and PCR amplification of integrons genes were used to confirm MDR. The results showed that the size of plasmid DNA is more than 52 Kb and the size of successfully amplified integron genes (I and II) were 175 and 250 bp respectively. Hospital isolate was confirmed as E.coli MDR on the basis of existence of integron genes

Correlation of total leukocyte count and platelets with the recovery phase in children with dengue admitted in an urban tertiary care center

Introduction: Dengue ranks among the most significant mosquito-borne viral diseases in the world. Anticipatory management and monitoring indicators are essential in effectively administering therapies in the critical phase. Only a few studies have explored and documented the relationship between laboratory parameters and convalescing children with dengue. Objectives: The objective of the study was to delineate correlation of total leukocyte count (TLC) and the onset of convalescence (recovery) phase in children with dengue, and second, to determine the correlation of platelet count and TLC with the duration of hospital stay. Materials and Methods: This prospective observational study was conducted in a tertiary care hospital in Nagpur from July 2018 to November 2018 when the dengue outbreak in the city and the vicinity of this central India region was at its peak. The inclusion criteria consisted of children of 1–18 years of age from either sex, fever of recent duration, and serological positivity for dengue (NS1 antigen and/or IgM and IgG antibody positivity) were included in the study. The exclusion criteria were febrile illness other than dengue, comorbid conditions such as HIV, bronchial asthma, congenital heart disease, and complicated dengue cases. Results: Out of 190 cases, 65.8% were males, the average duration of fever at the time of admission being 4.9±2.2 days (Range 2–10 days). The average duration of illness was 10.1±2.4 days (range 4–19 days). Eleven (5.79%) subjects had third spacing (capillary leak). The average TLC recovery time was 8.45±1.57 days (7–12days) from the onset of illness, while the mean capillary leak recovery time was 9.45±1.57 days (8–11days). A negative correlation was observed from a 2nd – day hospital stay with both TLC and platelets in patients with the capillary leak. Conclusion: In resource-limited settings, pediatricians can utilize TLC in predicting recovery, and thus can reduce the treatment costs

Fraud Voters Detection using Smart Electronic Voting Machine

The main aim of this project is to provide secured identification and authentication processes for the voters and candidates by using fingerprint and face detection. The basic idea of this project is to make an electronic voting machine that will help to reduce the manual voting systems and prior versions of electronic voting. This system includes multiple layers of verifications to ensure the reliability of the device. every voter is entered into the system after being diagnosed and checked with the given database of enlisted electorate with together with fingerprint sensor and Pi camera.The final vote is then displayed onto a monitoring system for the satisfaction of voters. The voting problem is still critical in terms of safety and security. This project is about the design and improvement of a machine the use of fingerprint and face detection to offer a high performance with excessive safety to the vote casting gadget. Fingerprint is broadly used for identification. The proposed undertaking displays transparency and also carries the function of being self sustaining during the route of operation. Election is the act of party casting votes to choose on man or woman for some type of function. Election may additionally involve a public or private vote relying on the position. maximum of the positions like local, state, and federal governments are balloting on in a few form of election. An electronic voting system defines valid voting and gives a fast method of counting votes, which helps to conclude a final result. In this project, we propose an idea to avoid fraud voting and increases security about the voting. Lot of methods have been developed to avoid fraudulence in voting systems, but we are not able to reduce it completely. This system is secure, transparent, reliable as well as easy to use for the citizens. We scan the finger print and face of every individual. The scanned finger print is authenticated, If matches the individual is allowed to cast the vote

Bioconversion of Weedy Waste into Sugary Wealth

Efforts put in overriding the inulin abundant invader nastiest category I weeds are infeasible that lead into its impermanent confiscation. Hence, their heedful exploitation is obligatory. These invasive weeds have ample amount of inulin, which serves as a renewable, cheap raw substrate for inulinase production. Therefore, they have enticed intention of many researchers toward exploring more idiosyncratic inulinase producing microbial strains that utilize invasive inulin-rich weeds as substrate for fructose liberation. Plenteous industrial applications of inulinases have marked it distinctly crucial in recent biotechnological epoch. This review thus elaborates the literature on infused footprints embedded by the substituted low calorie healthy sweetener in new advancing fields

Parkinsonism and Potential of Mucuna Beans

Parkinson’s is a neurodegenerative disease, which is common all over the world. Various aspect like damages of reactive oxygen species, excitotoxicity, mitochondrial dysfunction, and inflammation-facilitated cell damages are included in the etiology of disease. Good-balanced nutrition is an important part involved in the body health maintenance and reduction in the risk of chronic diseases. Genus Mucuna falls under family Fabaceae, containing high contents of L-DOPA (commonly used as an anti-Parkinson drug). Plant-based medicines are the superfluous source of polyphenols, flavonoids, carotenoids, antioxidants (ROS and RNS), terpenoids, isoflavonoids, and other biologically active phytochemicals. All these molecules have health beneficial effects with superlative pharmaceutical values. The existing chapter summaries to determine the influence of different nutritional, anti-nutritional, and medicinal potential of the Mucuna species present in India and its significance in the management of Parkinson’s disease (Shaking Palsy) as well as other medicinal values. It also covers various treatment models used in studying the Parkinson’s disease like Drosophila melanogaster, zebrafish, mice, rat, and humans. This chapter also focuses light on the neurosurgical treatments used in the treatment of Parkinson’s disease. This study concluded that the use of Mucuna seeds for the treatment of Parkinson’s disease is the best choice besides chemical drugs and other therapies

Sustainable supply chain management towards disruption and organizational ambidexterity:A data driven analysis

Balancing sustainability and disruption of supply chains requires organizational ambidexterity. Sustainable supply chains prioritize efficiency and economies of scale and may not have sufficient redundancy to withstand disruptive events. There is a developing body of literature that attempts to reconcile these two aspects. This study gives a data-driven literature review of sustainable supply chain management trends toward ambidexterity and disruption. The critical review reveals temporal trends and geographic distribution of literature. A hybrid of data-driven analysis approach based on content and bibliometric analyses, fuzzy Delphi method, entropy weight method, and fuzzy decision-making trial and evaluation laboratory is used on 273 keywords and 22 indicators obtained based on the experts’ evaluation. The most important indicators are identified as supply chain agility, supply chain coordination, supply chain finance, supply chain flexibility, supply chain resilience, and sustainability. The regions show different tendencies compared with others. Asia and Oceania, Latin America and the Caribbean, and Africa are the regions needs improvement, while Europe and North America show distinct apprehensions on supply chain network design. The main contribution of this review is the identification of the knowledge frontier, which then leads to a discussion of prospects for future studies and practical industry implementation