La prière de l'apôtre Paul (NH I, 1) : introduction, édition critique, traduction et commentaire

Tableau d’honneur de la Faculté des études supérieures et postdoctorales, 2012-2013.La Prière de l'apôtre Paul (NH I, 1) est une courte prière de requête inscrite sur la page de garde de l'un des treize codices découverts au milieu du XXe siècle près de Nag Hammadi, en Egypte. Comme pour la plupart des textes qui composent le corpus de Nag Hammadi, l'auteur, la date de composition originale et le parcours rédactionel de ce document sont difficiles, voire impossibles à déterminer de manière précise. Dans l'introduction, le mémoire situe la Prière de l'apôtre Paul dans son contexte matériel, historique, littéraire et doctrinal. Il en donne par la suite une édition critique et une traduction française, lesquelles contiennent quelques nouvelles restitutions et lectures qui améliorent notre compréhension du texte. Il fournit ensuite un commentaire, afin d'éclaircir certaines questions philologiques ou doctrinales. Un index des termes coptes et gréco-coptes y est également inclus

Scedosporiosis/lomentosporiosis observational study (SOS): Clinical significance of Scedosporium species identification

International audienceScedosporiosis/lomentosporiosis is a devastating emerging fungal infection. Our objective was to describe the clinical pattern and to analyze whether taxonomic grouping of the species involved was supported by differences in terms of clinical presentations or outcomes. We retrospectively studied cases of invasive scedosporiosis in France from 2005 through 2017 based on isolates characterized by polyphasic approach. We recorded 90 cases, mainly related to Scedosporium apiospermum (n = 48), S. boydii/S. ellipsoideum (n = 20), and Lomentospora prolificans (n = 14). One-third of infections were disseminated, with unexpectedly high rates of cerebral (41%) and cardiovascular (31%) involvement. In light of recent Scedosporium taxonomic revisions, we aimed to study the clinical significance of Scedosporium species identification and report for the first time contrasting clinical presentations between infections caused S. apiospermum, which were associated with malignancies and cutaneous involvement in disseminated infections, and infections caused by S. boydii, which were associated with solid organ transplantation, cerebral infections, fungemia, and early death. The clinical presentation of L. prolificans also differed from that of other species, involving more neutropenic patients, breakthrough infections, fungemia, and disseminated infections. Neutropenia, dissemination, and lack of antifungal prescription were all associated with 3-month mortality. Our data support the distinction between S. apiospermum and S. boydii and between L. prolificans and Scedosporium sp. Our results also underline the importance of the workup to assess dissemination, including cardiovascular system and brain. Lay Summary Scedosporiosis/lomentosporiosis is a devastating emerging fungal infection. Our objective was to describe the clinical pattern and to analyze whether taxonomic grouping of the species involved was supported by differences in terms of clinical presentations or outcomes