Alkyne Cyclizations: From α-Carbonyl Bicyclic Furans to Expanded Chiral Hexa-peri-hexabenzocoronenes

The development and utilization of highly functionalized and reactive dienophiles in the Diels–Alder cyclization reaction is of value in producing diversely functionalized, and therefore useful, cyclic products. We have developed a Diels–Alder reaction of conjugated 2,4-diynones, promoted by Lewis acids (Me2AlCl or EtAlCl2), to produce substituted 2-alkynyl-1,4-cyclohexadiene (‘skipped’ cyclohexadiene) products in good to excellent yields. The reaction was successful with a variety of cyclic and acyclic dienes as well as with a diversity of 2,4-diynones. The diversely functionalized 1,4-cyclohexadiene products that are obtained from this reaction are of utility as intermediates on the way to synthesizing pharmaceutically relevant cyclic and polycyclic compounds. Those heavily functionalized skipped dienes were cleanly converted into dihydroisobenzofuran (bicyclic furan) derivatives in the presence of π-Lewis acid catalysts. Ketone derivatives were obtained by using CuCl2 as catalyst whereas AgNO3 provides aldehyde analogues. We have also demonstrated a facile one-pot approach to construct bicyclic furan derivatives directly from diynone and diene starting materials.We also describe the synthesis, characterization, structure and properties of expanded chiral hexa-peri-hexabenzocoronenes. The Suzuki cross-coupling between bromo substituted hexa-peri-hexabenzocoronene and diynylphenyl borate gives the coupled product. The alkyne benzannulation reaction of coupled product promoted by a mixture of TFA and TfOH afforded the desired final product. The twisted structure of chiral compounds is unambiguously confirmed by X-ray crystallographic analysis and the enantiomers are separated in chiral HPLC

Mars laser altimeter based on a single photon ranging technique

The Mars 94/96 Mission will carry, among others things, the balloon probe experiment. The balloon with the scientific cargo in the gondola underneath will drift in the Mars atmosphere, its altitude will range from zero, in the night, up to 5 km at noon. The accurate gondola altitude will be determined by an altimeter. As the Balloon gondola mass is strictly limited, the altimeter total mass and power consumption are critical; maximum allowed is a few hundred grams a few tens of mWatts of average power consumption. We did propose, design, and construct the laser altimeter based on the single photon ranging technique. Topics covered include the following: principle of operation, altimeter construction, and ground tests

Rapid gains in yield and adoption of new maize varieties for complex hillside environments through farmer participation. II. Scaling-up the adoption through community-based seed production (CBSP)

Participatory varietal selection (PVS) led to the identification of Population-22 and its later release as Manakamana-3. Subsequently further mother–baby trials tested five unreleased open-pollinated varieties (OPVs), ZM-621, Shitala, Population-45, Hill Pool White, and Hill Pool Yellow to compare them with Manakamana-3. Farmers again preferred Manakamana-3 as well as ZM-621 for their stable, higher grain yield, and for other traits such as stay-green, non-lodging, large white grains, and tolerance to foliar diseases. However, Manakamana- 3 and ZM-621 both had late maturity, open husks and dented grain. Both were tested with farmers on-farm coordinated farmers field trials (CFFTs) and had not been identified as this was more contractual type of participatory research. Individual traits were measured but overall farmers’ preferences were not elicited. In the more collaborative participation of the mother– baby trials the overall preference was determined and farmers traded-off the late maturity and dented grains of Manakamana-3 and ZM-621 against other favorable traits. Depending on location, these genotypes yielded 15–45% more grain than the local varieties in the mother–baby trials. These results led to the release of ZM-621 as Deuti in 2006. Farmers had adopted Manakamana-3 (released in 2002) and ZM-621 (Deuti) as a direct result of PVS trials and increased area under them year after year. Farmers awareness of the varieties has increased and seeds of these varieties are under community-based seed production (CBSP). Involving farmers through a collaborative mode of participation in varietal selection overcame bottlenecks to finding new varieties that had occurred with more contractual on-farm research

A First Search for coincident Gravitational Waves and High Energy Neutrinos using LIGO, Virgo and ANTARES data from 2007

We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - September 2007, which coincided with the fifth and first science runs of LIGO and Virgo, respectively. The LIGO-Virgo data were analysed for candidate gravitational-wave signals coincident in time and direction with the neutrino events. No significant coincident events were observed. We place limits on the density of joint high energy neutrino - gravitational wave emission events in the local universe, and compare them with densities of merger and core-collapse events.Comment: 19 pages, 8 figures, science summary page at http://www.ligo.org/science/Publication-S5LV_ANTARES/index.php. Public access area to figures, tables at https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p120000

Measurement of Atmospheric Neutrino Oscillations with the ANTARES Neutrino Telescope

The data taken with the ANTARES neutrino telescope from 2007 to 2010, a total live time of 863 days, are used to measure the oscillation parameters of atmospheric neutrinos. Muon tracks are reconstructed with energies as low as 20 GeV. Neutrino oscillations will cause a suppression of vertical upgoing muon neutrinos of such energies crossing the Earth. The parameters determining the oscillation of atmospheric neutrinos are extracted by fitting the event rate as a function of the ratio of the estimated neutrino energy and reconstructed flight path through the Earth. Measurement contours of the oscillation parameters in a two-flavour approximation are derived. Assuming maximum mixing, a mass difference of $\Delta m_{32}^2=(3.1\pm 0.9)\cdot 10^{-3}$ eV$^2$ is obtained, in good agreement with the world average value.Comment: 9 pages, 5 figure

Measurement of χ c1 and χ c2 production with s√ = 7 TeV pp collisions at ATLAS

The prompt and non-prompt production cross-sections for the χ c1 and χ c2 charmonium states are measured in pp collisions at s√ = 7 TeV with the ATLAS detector at the LHC using 4.5 fb−1 of integrated luminosity. The χ c states are reconstructed through the radiative decay χ c → J/ψγ (with J/ψ → μ + μ −) where photons are reconstructed from γ → e + e − conversions. The production rate of the χ c2 state relative to the χ c1 state is measured for prompt and non-prompt χ c as a function of J/ψ transverse momentum. The prompt χ c cross-sections are combined with existing measurements of prompt J/ψ production to derive the fraction of prompt J/ψ produced in feed-down from χ c decays. The fractions of χ c1 and χ c2 produced in b-hadron decays are also measured

Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009 and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncertainty for single charged and neutral particles to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3% for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table, submitted to European Physical Journal

Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector

The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30

Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

This paper presents measurements of the $W^+ \rightarrow \mu^+\nu$ and $W^- \rightarrow \mu^-\nu$ cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13