PLASMID PROFILING OF EXTENDED SPECTRUM Β-LACTAMASES PRODUCING ESCHERICHIA COLI IN SOME HOSPITALS IN BAGHDAD

This study was aimed to determine the prevalence of ESBLs in E. coli and their relation to plasmid profiling patterns in a sample of patients in Iraqi hospitals. The total number of E. coli isolates 91 (49%) were collected out of 185 clinical samples. The antibiotic sensitivity test for isolates showed high resistance percentage to Nitrofurantion 95.7%, amoxicillin and Ceftriaxone to each of which 91.3% and to Ceftazidime 90.2%, while the highest sensitivity was observed against Imipenem 100%, Meropenem 99% then to Amikacin 93.5%. The Multi drug resistant (MDR) isolates were 53(58.2) % and ESBLs producers were 45 (49.5) %. Plasmid profile analysis showed nineteen different plasmid profile patterns were obtained based on molecular weight and number of plasmids content. Most β-lactamase producers had multiple plasmids, where’s single plasmid profile predominant in non-β-lactamase-producing isolates. The presence of common plasmid among the isolates increases the distribution of resistant plasmid in the community. In conclusion, ESBLs producing bacteria can transferred between species by plasmids leading to cross resistance which give a limited options for treatment

Transverse momentum spectra of charged particles in proton-proton collisions at 1as=900 GeV with ALICE at the LHC

The inclusive charged particle transverse momentum distribution is measured in proton-proton collisions at s=900 GeV at the LHC using the ALICE detector. The measurement is performed in the central pseudorapidity region (|\u3b7|<0.8) over the transverse momentum range 0.15<10 GeV/c. The correlation between transverse momentum and particle multiplicity is also studied. Results are presented for inelastic (INEL) and non-single-diffractive (NSD) events. The average transverse momentum for |\u3b7|<0.8 is \u3008pT\u3009INEL=0.483\ub10.001 (stat.)\ub10.007 (syst.) GeV/c and \u3008pT\u3009NSD=0.489\ub10.001 (stat.)\ub10.007 (syst.) GeV/c, respectively. The data exhibit a slightly larger \u3008pT\u3009 than measurements in wider pseudorapidity intervals. The results are compared to simulations with the Monte Carlo event generators PYTHIA and PHOJET. \ua9 2010