36 research outputs found
Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment
- Author
- Publication venue
- Cell Reports
- Publication date
- 01/05/2017
- Field of study
Aging of the hematopoietic stem cell (HSC) compartment is characterized by lineage bias and reduced stem cell function, the molecular basis of which is largely unknown. Using single-cell transcriptomics, we identified a distinct subpopulation of old HSCs carrying a p53 signature indicative of stem cell decline alongside pro-proliferative JAK/STAT signaling. To investigate the relationship between JAK/STAT and p53 signaling, we challenged HSCs with a constitutively active form of JAK2 (V617F) and observed an expansion of the p53-positive subpopulation in old mice. Our results reveal cellular heterogeneity in the onset of HSC aging and implicate a role for JAK2V617F-driven proliferation in the p53-mediated functional decline of old HSCs
Novel variation and <i>de novo </i>mutation rates in population-wide <i>de novo</i> assembled Danish trios
- Author
- Belling Kirstine C.
- Besenbacher Søren
- Bolund Lars
- Bork-Jensen Jette
- Brunak Søren
- Børglum Anders D.
- Cheng Xiaofang
- Chmura Piotr Jaroslaw
- Dam-Als Thomas
- Demontis Ditte
- Dworzynski Piotr
- Eiberg Hans
- Flores Santa Cruz David
- Friborg Rune M.
- Gonzalez-Izarzugaza Jose Maria
- Grove Jakob
- Gupta Ramneek
- Hansen Torben
- Huang Shujia
- Jun Wang
- Kristiansen Karsten
- Krogh Anders
- Lescai Francesco
- Li Ning
- Li Shengting
- Liu Hao
- Liu Siyang
- Lund Ole
- Mailund Thomas
- Pedersen Christian N. S.
- Pedersen Oluf
- Rao Junhua
- Rapacki Kristoffer
- Rasmussen Simon
- Rubio García Arcadio
- Rydza Emil Karol
- Schierup Mikkel H
- Sun Jihua
- Sørensen John Damm
- Sørensen Thorkild I. A.
- Villesen Palle
- Wang Ou
- Westergaard David
- Xu Ruiqi
- Xu Xun
- Yadav Rachita
- Yadav Rachita
- Ye Weijian
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Building a population-specific catalogue of single nucleotide variants (SNVs), indels and structural variants (SVs) with frequencies, termed a national pan-genome, is critical for further advancing clinical and public health genetics in large cohorts. Here we report a Danish pan-genome obtained from sequencing 10 trios to high depth (50 × ). We report 536k novel SNVs and 283k novel short indels from mapping approaches and develop a population-wide de novo assembly approach to identify 132k novel indels larger than 10 nucleotides with low false discovery rates. We identify a higher proportion of indels and SVs than previous efforts showing the merits of high coverage and de novo assembly approaches. In addition, we use trio information to identify de novo mutations and use a probabilistic method to provide direct estimates of 1.27e−8 and 1.5e−9 per nucleotide per generation for SNVs and indels, respectively
Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.
- Author
- Ab Majid MA
- Ab Rahman AS
- Ab Rahman R
- Abayasinghe C
- Abbott T
- Abdullah NH
- Abdur-Rahman L
- Abeloos J
- Abernethy C
- Abidin UN
- Abrunhosa A
- Absar M
- Adam S
- Adams D
- Adams G
- Adamson M
- Adekola O
- Adelaja Y
- Ademola A
- Adenekan A
- Adenike O
- Adeolu AA
- Adetoye A
- Adewale B
- Adigun T
- Adolfsson A
- Aflori L
- Africander C
- Afshari A
- Agarwal V
- Agodirin O
- Aguero Vera M
- Aguzzoli C
- Ahmad A
- Ahmad N
- Ahmad T
- Ahmad T
- Ahmad Y
- Ahmed A
- Ahmed J
- Ai Y
- Aignatoaie M
- Aimoniotou-Georgiou E
- Akanmu O
- Akerman N
- Akinwale M
- Akring I
- Al 'Amri K
- Al Anizi M
- Al hussaini S
- Al-Soudaine Y
- Aladin H
- Alagbe-Briggs O
- Alaman Laguarda G
- Albaj S
- Alcock D
- Alcock L
- Aldecoa C
- Aldecoa C
- Aleixo FB
- Alexander H
- Alexander M
- Alexander-Sefre F
- Alherz F
- Ali H
- Ali M
- Ali S
- Alias A
- Alias AH
- Alias RLR
- Alit MA
- Allen S
- Allen SJ
- Allison J
- Alloj C
- Allorto NL
- Allsop J
- Almeida W
- Alonso E
- Alphonsus C
- Alvares D
- Alves MJ
- Amador JCB
- Ameer Y
- Amendola CP
- Ami N
- Amstrup-Hansen L
- Anagnou A
- Andersen C
- Anderson C
- Anderson C
- Anderson F
- Anderson P
- Andreadaki E
- Andreou A
- Andreou P
- Andrew A
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- Angermair S
- Angus K
- Anillo V
- Antal O
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- Apostolou K
- Applewhaite C
- Aquino LPG
- Ar P
- Arawwawala D
- Ardern D
- Argue R
- Arkalaki E
- Armaganidis A
- Armstrong J
- Armstrong R
- Arnaoutoglou C
- Arnaoutoglou E
- Arnold G
- Arrandale L
- Arrich J
- Arrigo M
- Arshad H
- Arshad MA
- Arumugam S
- Arustei M
- Arvaniti K
- Arya A
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- Asimakos A
- Asudo F
- Athanasakis E
- Atiku M
- Attrill E
- Attwood C
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- Avila Sanchez FJ
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- Azam UAA
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- Baghirzada L
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- Bandeira ME
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- Chisbert Cuenca V
- Chlorou D
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- Christofaki M
- Christoforidis D
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- Yap HL
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- Yip CP
- Yong J
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- Yuliana A
- Zaimi D
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- Zamudio D
- Zangrillo A
- Zapata DDM
- Zbitnew G
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- Zhao B
- Zhao C
- Zhao J
- Zhao J
- Zhao L
- Zhao L
- Zhao S
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- Zhou H
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- Zhou J
- Zhou J
- Zhou J
- Zhou X-J
- Zhu X
- Zhu X
- Zhu Y
- Zhu Z
- Zhuang X
- Zilis G
- Zin NHM
- Zingerle N
- Zingg U
- Zoerner F
- Zonneveldt H
- Zou X
- Zoulamoglou M
- Zsisku L
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2016
- Field of study
BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700
El Perú frente al cambio climático
- Author
- A Cochachin
- A. Bertrand
- A. Montecinos
- A. Paulmier
- A. Rabatel
- A. Santiago
- A. Tacsi
- A.M. Rodríguez del Castillo
- Albuquerque AL.S.
- Apaestegui J.
- B. Dewitte
- B. Turcq
- Belem A.
- Bernal J.R
- C. Espinoza J.
- C. Junquas
- C. Jézéquel
- Cheng H.
- Cordeiro R.C.
- D. Colonia
- D. Gutierrez
- D. Labat
- da Cruz W.
- E.A. Chavarri
- F. Carvajal-Vallejos
- F. Chiock
- F. Duponchelle
- Fabius Laurent
- G. Cochonneau
- Gutierrez D.
- Guyot J-L.
- H. Ortega
- I. Montes
- I. Quintana Cobo
- J. Apaestegui
- J. Rojas-Fox
- J. Roncal
- J. Ronchail
- J. Tam
- J. Tejada
- J. Torres
- J.A. Maldonado-Ocampo
- J.C Pintaud
- J.C. Espinoza
- J.C. Pintaud
- J.E. Sicart
- J.F. Cornu
- J.F. Renno
- J.L Guyot
- J.L. Guyot
- J.M. Martínez
- K. Aniceto
- K. Goubanova
- K. Mejía
- K. Mosquera
- K. Takahashi
- L. Bourrel
- L. Dávila
- L. Mourre
- L. Santa Cruz
- L.S. Moreira
- Laurent Michel
- Leite da Silva Dias P.
- M. Campero
- M. Guimberteau
- M. Roddaz
- M. Villacis
- M.S. Dias
- Moreira-Turcq P.
- N. Santillán
- Ortlieb L.
- P Rau
- P. Baby
- P. Moreira-Turcq
- P. Vauchel
- P.1 Fraizy
- P.A. Tedesco
- P.O. Antoine
- Pulgar Vidal Manuel
- R. Espinoza-Villar
- R. Flores
- R. Ramírez
- R. Salas-Gismondi
- R.C Cordeiro
- S. Byron Morera
- S. Illig
- S. Purca
- Sifeddine A.
- T. Condom
- T. Oberdorff
- Turcq B.
- V. Echevin
- V. Garçon
- V. Jimenez
- Velazco F.
- W Lavado
- W. Lavado
- W. Santini
- W. Suarez
- Y. Calderon
- Publication venue
- 'OpenEdition'
- Publication date
- 20/11/2018
- Field of study
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Agdeppa Imelda A.
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Naser
- Ahmadvand Alireza
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M.
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Ali Osman
- Alkerwi Ala'a
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N.
- Amouyel Philippe
- Amuzu Antoinette
- Anderssen Sigmund A.
- Angquist Lars H.
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Anselmo Olinto Maria Teresa
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V.
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L.
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R.
- Barbagallo Carlo M.
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio J. D.
- Barros Mauro V. G.
- Bata Iqbal
- Batieha Anwar M.
- Batista Rosangela L.
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
- Bennett James E.
- Bentham James
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K.
- Bhutta Zulfiqar A.
- Bi Hongsheng
- Bi Yufang
- Biehl Anna
- Bikbov Mukharram
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J.
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B.
- Bjorkelund Cecilia
- Blokstra Anneke
- Bo Lars
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- Bobak Martin
- Boddy Lynne M.
- Boehm Bernhard O.
- Boeing Heiner
- Boggia Jose G.
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- Borchini Rossana
- Borghs Herman
- Bovet Pascal
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn C. E.
- Brajkovich Imperia
- Branca Francesco
- Braunerova Radka Taxova
- Breckenkamp Jürgen
- Breda Joao
- Brenner Hermann
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- Brian Garry R.
- Brinduse Lacramioara
- Bruno Graziella
- Bueno-de-Mesquita H. Bas
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Cabrera de Leon Antonio
- Cacciottolo Joseph
- Cai Hui
- Cama Tilema
- Cameron Christine
- Camolas Jose
- Can Gamze
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- Canete Felicia
- Capanzana Mario V.
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- Carrillo-Larco Rodrigo M.
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- Caserta Carmelo A.
- Celikcan Ertugrul
- Censi Laura
- Cesar Juraci A.
- Chamukuttan Snehalatha
- Chan Angelique W.
- Chan Queenie
- Chaturvedi Himanshu K.
- Chaturvedi Nishi
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheng Yiling J.
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Cho Yumi
- Christensen Kaare
- Christofaro Diego G.
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Claessens Frank
- Clarke Janine
- Clays Els
- Concin Hans
- Confortin Susana C.
- Cooper Cyrus
- Coppinger Tara C.
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J.
- Cowell Chris
- Craig Cora L.
- Crampin Amelia C.
- Crujeiras Ana B.
- Cruz Juan J.
- Cucu Alexandra
- Cui Liufu
- D'Arrigo Graziella
- d'Orsi Eleonora
- Dallongeville Jean
- Damasceno Albertino
- Damsgaard Camilla T.
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M.
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- De Curtis Amalia
- de Gaetano Giovanni
- De Henauw Stefaan
- de Oliveira Paula Duarte
- De Ridder Karin
- de Rooij Susanne R.
- De Smedt Delphine
- de Wit Tobias F. Rinke
- Deepa Mohan
- Deev Alexander D.
- Dehghan Abbas
- del Cristo Rodriguez-Perez Maria
- Delisle Helene
- Delpeuch Francis
- Dennison Elaine
- Deschamps Valerie
- Dhana Klodian
- Dhimal Meghnath
- Di Castelnuovo Augusto F.
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Dika Zivka
- Djalalinia Shirin
- Do Ha T. P.
- Dobson Annette J.
- Doering Angela
- Donati Maria Benedetta
- Donfrancesco Chiara
- Donoso Silvana P.
- Dorobantu Maria
- Dorosty Ahmad Reza
- Doua Kouamelan
- Drygas Wojciech
- Duan Jia Li
- Duante Charmaine A.
- Duda Rosemary B.
- Duleva Vesselka
- Dulskiene Virginija
- Dumith Samuel C.
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Eddie Ricky
- Egbagbe Eruke E.
- Eggertsen Robert
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- Eldemire-Shearer Denise
- Eliasen Marie
- Elliott Paul
- Engle-Stone Reina
- Erasmus Rajiv T.
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G.
- Escobedo-de la Pena Jorge
- Evans Alun
- Ezzati Majid
- Faeh David
- Fall Caroline H.
- Farzadfar Farshad
- Fattahi Mohammad R.
- Felix-Redondo Francisco J.
- Ferguson Trevor S.
- Fernandes Romulo A.
- Fernandez-Berges Daniel
- Ferrante Daniel
- Ferrari Marika
- Ferreccio Catterina
- Ferrer Eldridge
- Ferrieres Jean
- Fijalkowska Anna
- Fink Gunther
- Fischer Krista
- Flores Eric Monterubio
- Foeger Bernhard
- Foo Leng Huat
- Forslund Ann-Sofie
- Forsner Maria
- Fouad Heba M.
- Francis Damian K.
- Francisco Miquel Juan
- Franco Maria do Carmo
- Franco Oscar H.
- Frontera Guillermo
- Fuchs Flavio D.
- Fuchs Sandra C.
- Fujita Yuki
- Furusawa Takuro
- Gaciong Zbigniew
- Gafencu Mihai
- Galeone Daniela
- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- Gareta Dickman
- Garnett Sarah P.
- Gaspoz Jean-Michel
- Gasull Magda
- Gates Louise
- Gazzinelli Andrea
- Geiger Harald
- Geleijnse Johanna M.
- Ghaffar Suhaila Abdul
- Ghanbari Ali
- Ghasemi Erfan
- Ghasemian Anoosheh
- Gheorghe-Fronea Oana-Florentina
- Giampaoli Simona
- Gianfagna Francesco
- Gill Tiffany K.
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Godos Justyna
- Gogen Sibel
- Goldsmith Rebecca A.
- Goltzman David
- Goncalves Helen
- Gonzalez Angel R.
- Gonzalez-Chica David A.
- Gonzalez-Gross Marcela
- Gonzalez-Leon Margot
- Gonzalez-Rivas Juan P.
- Gonzalez-Villalpando Maria-Elena
- Gottrand Frederic
- Graca Antonio Pedro
- Graff-Iversen Sidsel
- Grafnetter Dusan
- Grajda Aneta
- Grammatikopoulou Maria G.
- Gregg Edward W.
- Gregor Ronald D.
- Grodzicki Tomasz
- Grontved Anders
- Grosso Giuseppe
- Gruden Gabriella
- Gu Dongfeng
- Gualdi-Russo Emanuela
- Gudmundsson Elias F.
- Gudnason Vilmundur
- Guerrero Ramiro
- Guessous Idris
- Guimaraes Andre L.
- Gulliford Martin C.
- Gunnlaugsdottir Johanna
- Gunter Marc
- Guo Xiuhua
- Guo Yin
- Gupta Prakash C.
- Gupta Rajeev
- Gureje Oye
- Gurzkowska Beata
- Gutierrez Laura
- Gutzwiller Felix
- Hadaegh Farzad
- Hadjigeorgiou Charalambos A.
- Haghshenas Rosa
- Halkjaer Jytte
- Hambleton Ian R.
- Hamid Zargar Abdul
- Hardy Rebecca
- Hassapidou Maria
- Hata Jun
- Haugsgjerd Teresa
- Hayes Alison J.
- He Jiang
- He Yuna
- Heidinger-Felso Regina
- Heinen Mirjam
- Hejgaard Tatjana
- Hendriks Marleen Elisabeth
- Henriques Ana
- Hernandez Cadena Leticia
- Herrala Sauli
- Herrera Victor M.
- Herter-Aeberli Isabelle
- Heshmat Ramin
- Hill Allan G.
- Ho Sai Yin
- Ho Suzanne C.
- Hobbs Michael
- Hofman Albert
- Hopman Wilma M.
- Horimoto Andrea R. V. R.
- Hormiga Claudia M.
- Horta Bernardo L.
- Houti Leila
- Howitt Christina
- Htay Thein Thein
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta Jose Maria
- Huhtaniemi Ilpo Tapani
- Huisman Martijn
- Husseini Abdullatif
- Huybrechts Inge
- Hwalla Nahla
- Hyska Jolanda
- Iacoviello Licia
- Ibarluzea Jesus M.
- Ibrahim Mohsen M.
- Ikeda Nayu
- Ikram M. Arfan
- Ioannidou Eliza Markidou
- Irazola Vilma E.
- Ishida Takafumi
- Islam Muhammad
- Ismail Aziz al-Safi
- Iurilli Maria L. C.
- Ivkovic Vanja
- Iwasaki Masanori
- Jaaskelainen Tuija
- Jackson Rod T.
- Jacobs Jeremy M.
- Jaddou Hashem
- Jafar Tazeen
- James Kenneth
- Jamil Kazi M.
- Jamrozik Konrad
- Janszky Imre
- Janus Edward
- Jarani Juel
- Jarvelin Marjo-Riitta
- Jasienska Grazyna
- Jelakovic Ana
- Jelakovic Bojan
- Jennings Garry
- Jeong Seung-Lyeal
- Jerome Charles Sossa
- Jiang Chao Qiang
- Jimenez Ramon O.
- Joffres Michel
- Johansson Mattias
- Jokelainen Jari J.
- Jonas Jost B.
- Jorgensen Torben
- Joshi Pradeep
- Jovic Dragana P.
- Jozwiak Jacek
- Juolevi Anne
- Jurak Gregor
- Juresa Vesna
- Kaaks Rudolf
- Kafatos Anthony
- Kajantie Eero O.
- Kalter-Leibovici Ofra
- Kamaruddin Nor Azmi
- Kameli Yves
- Kapantais Efthymios
- Karki Khem B.
- Kasaeian Amir
- Katibeh Marzieh
- Katz Joanne
- Katzmarzyk Peter T.
- Kauhanen Jussi
- Kaur Prabhdeep
- Kavousi Maryam
- Kazakbaeva Gyulli
- Keil Ulrich
- Keinan-Boker Lital
- Keinanen-Kiukaanniemi Sirkka
- Kelishadi Roya
- Kelleher Cecily
- Kemper Han C. G.
- Kengne Andre P.
- Kerimkulova Alina
- Kersting Mathilde
- Key Timothy
- Khader Yousef Saleh
- Khalili Davood
- Khang Young-Ho
- Khanh Le Nguyen Bao Khanh Le Nguyen Bao
- Khateeb Mohammad
- Khaw Kay-Tee
- Kheiri Bahareh
- Khosravi Alireza
- Khouw Ilse M. S. L.
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
- Killewo Japhet
- Kim Jeongseon
- Kim Yeon-Yong
- Klimont Jeannette
- Klumbiene Jurate
- Knoflach Michael
- Koenig Jurgen
- Koirala Bhawesh
- Kolle Elin
- Kolsteren Patrick
- Korpelainen Raija
- Korrovits Paul
- Korzycka Magdalena
- Koskinen Seppo
- Kouda Katsuyasu
- Kovacs Viktoria A.
- Kowlessur Sudhir
- Koziel Slawomir
- Kratzer Wolfgang
- Kriemler Susi
- Kristensen Peter Lund
- Krokstad Steinar
- Kromhout Daan
- Kruger Herculina S.
- Kubinova Ruzena
- Kuciene Renata
- Kuh Diana
- Kujala Urho M.
- Kujundzic Enisa
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- Kumar R. Krishna
- Kumar Rachakulla Hari
- Kunesova Marie
- Kurjata Pawel
- Kusuma Yadlapalli S.
- Kuulasmaa Kari
- Kyobutungi Catherine
- Laamiri Fatima Zahra
- Laatikainen Tiina
- Lachat Carl
- Laid Youcef
- Lanska Vera
- Lappas Georg
- Larijani Bagher
- Latt Tint Swe
- Laugsand Lars E.
- Lauria Laura
- Laxmaiah Avula
- Lazo-Porras Maria
- Le Port Agnes
- Le Tuyen D.
- Lee Jeannette
- Lee Jeonghee
- Lee Paul H.
- Lehtimaki Terho
- Lele Elysee Claude Bika
- Lemogoum Daniel
- Levitt Naomi S.
- Li Yanping
- Lilly Christa L.
- Lim Wei-Yen
- Lima-Costa M. Fernanda
- Lin Hsien-Ho
- Lin Xu
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- Linneberg Allan
- Lissner Lauren
- Litwin Mieczyslaw
- Liu Jing
- Loit Helle-Mai
- Lopes Luis
- Lopez Tania
- Lopez-Garcia Esther
- Lorbeer Roberto
- Lotufo Paulo A.
- Lozano Jose Eugenio
- Luksiene Dalia
- Lundqvist Annamari
- Lundqvist Robert
- Lunet Nuno
- Lytsy Per
- Ma Guansheng
- Ma Jun
- Machado-Coelho George L. L.
- Machado-Rodrigues Aristides M.
- Machi Suka
- Maggi Stefania
- Magliano Dianna J.
- Magriplis Emmanuella
- Maire Bernard
- Majer Marjeta
- Makdisse Marcia
- Malekzadeh Fatemeh
- Malekzadeh Reza
- Malhotra Rahul
- Malyutina Sofia
- Maniego Lynell V.
- Manios Yannis
- Mann Jim I.
- Manzato Enzo
- Margozzini Paula
- Markaki Anastasia
- Markey Oonagh
- Marques Larissa Pruner
- Marques-Vidal Pedro
- Marrugat Jaume
- Martin Rosemarie
- Martin-Prevel Yves
- Martorell Reynaldo
- Martos Eva
- Marventano Stefano
- Masoodi Shariq R.
- Mathiesen Ellisiv B.
- Mathur Prashant
- Matijasevich Alicia
- Matsha Tandi E.
- Mazur Artur
- Mbanya Jean Claude N.
- McFarlane Shelly R.
- McGarvey Stephen T.
- Mckee Martin
- McLachlan Stela
- McLean Rachael M.
- McLean Scott B.
- McNulty Breige A.
- Mediene-Benchekor Sounnia
- Medzioniene Jurate
- Mehdipour Parinaz
- Meirhaeghe Aline
- Meisfjord Jorgen
- Meisinger Christa
- Menezes Ana Maria B.
- Menon Geetha R.
- Mensink Gert B. M.
- Mereke Alibek
- Meshram Indrapal I.
- Metspalu Andres
- Meyer Haakon E.
- Mi Jie
- Michaelsen Kim F.
- Michels Nathalie
- Mikkel Kairit
- Milanovic Sanja Music
- Miller Jody C.
- Minderico Claudia S.
- Minh Hoang Van
- Miranda J. Jaime
- Mirkopoulou Daphne
- Mirrakhimov Erkin
- Misigoj-Durakovic Marjeta
- Mistretta Antonio
- Mocanu Veronica
- Modesti Pietro A.
- Moghaddam Sahar Saeeidi
- Mohajer Bahram
- Mohamed Mostafa K.
- Mohammad Kazem
- Mohammadifard Noushin
- Mohamud Wan Nazaimoon Wan
- Mohan Viswanathan
- Mohanna Salim
- Mohebi Farnam
- Moitry Marie
- Molbo Drude
- Mollehave Line T.
- Moller Niels C.
- Molnar Denes
- Momenan Amirabbas
- Mondo Charles K.
- Monterrubio Eric A.
- Monyeki Kotsedi Daniel K.
- Moon Jin Soo
- Moreira Leila B.
- Morejon Alain
- Moreno Luis A.
- Morgan Karen
- Morin Suzanne
- Morovic Maja Lang
- Mortensen Erik Lykke
- Moschonis George
- Mossakowska Malgorzata
- Mostafa Aya
- Mota Jorge
- Mota-Pinto Anabela
- Motlagh Mohammad Esmaeel
- Motta Jorge
- Msyamboza Kelias P.
- Mu Thet Thet
- Muc Magdalena
- Mueller-Nurasyid Martina
- Mugosa Boban
- Muiesan Maria Lorenza
- Mukhtorova Parvina
- Murphy Neil
- Mursu Jaakko
- Murtagh Elaine M.
- Musil Vera
- Nabipour Iraj
- Naderimagham Shohreh
- Nagel Gabriele
- Naidu Balkish M.
- Nakamura Harunobu
- Namesna Jana
- Nang Ei Ei K.
- Nangia Vinay B.
- Nankap Martin
- Narake Sameer
- Nardone Paola
- Nauck Matthias
- Navarrete-Munoz Eva Maria
- Neal William A.
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- Neovius Martin
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- Nguyen Chung T.
- Nguyen Nguyen D.
- Nieto-Martinez Ramfis E.
- Ning Guang
- Ninomiya Toshiharu
- Nishtar Sania
- Noale Marianna
- Noboa Oscar A.
- Norat Teresa
- Norie Sawada
- Noto Davide
- Nurk Eha
- Nyirenda Moffat
- O'Neill Terence W.
- O'Reilly Dermot
- Obreja Galina
- Ochoa-Aviles Angelica M.
- Oda Eiji
- Oh Kyungwon
- Ohara Kumiko
- Ohtsuka Ryutaro
- Olafsson Orn
- Oliveira Isabel O.
- Oltarzewski Maciej
- Omar Mohd Azahadi
- Onat Altan
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- Paccaud Fred Michel
- Paciorek Christopher J.
- Padez Cristina
- Pagkalos Ioannis
- Pahomova Elena
- Pajak Andrzej
- Palli Domenico
- Palloni Alberto
- Palmieri Luigi
- Pan Wen-Harn
- Panda-Jonas Songhomitra
- Pandey Arvind
- Panza Francesco
- Papandreou Dimitrios
- Park Soon-Woo
- Parnell Winsome R.
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- Pascanu Ionela M.
- Patel Nikhil D.
- Pecin Ivan
- Pednekar Mangesh S.
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- Peixoto Sergio Viana
- Peltonen Markku
- Pereira Alexandre C.
- Perez Cynthia M.
- Perez-Farinos Napoleon
- Peters Annette
- Petersmann Astrid
- Petkeviciene Janina
- Petrauskiene Ausra
- Petrescu Constanta Huidumac
- Peykari Niloofar
- Pierannunzio Daniela
- Pigeot Iris
- Pikhart Hynek
- Pilav Aida
- Pilotto Lorenza
- Pistelli Francesco
- Pitakaka Freda
- Piwonska Aleksandra
- Plans-Rubio Pedro
- Poh Bee Koon
- Pohlabeln Hermann
- Pop Raluca M.
- Popovic Stevo R.
- Porta Miquel
- Portegies Marileen L. P.
- Posch Georg
- Poulimeneas Dimitrios
- Pouraram Hamed
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- Poustchi Hossein
- Pradeepa Rajendra
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- Price Jacqueline F.
- Puder Jardena J.
- Pudule Iveta
- Puhakka Soile E.
- Puiu Maria
- Punab Margus
- Qasrawi Radwan F.
- Qorbani Mostafa
- Quang Ngoc La Quang Ngoc La
- Quang Ngoc Nguyen Quang Ngoc Nguyen
- Radhika Madhari S.
- Radic Ivana
- Radisauskas Ricardas
- Rahim Norsyamlina Che Abdul
- Rahman Mahfuzar
- Rahman Mahmudur
- Raitakari Olli
- Raj Manu
- Rajkumar Hemalatha
- Rakhmatulloev Sherali
- Ramachandran Ambady
- Ramke Jacqueline
- Ramos Elisabete
- Ramos Rafel
- Rampal Lekhraj
- Rampal Sanjay
- Rao Kodavanti Mallikharjuna
- Rao Sudha Ramachandra
- Rascon-Pacheco Ramon A.
- Rasmussen Mette
- Redon Josep
- Reganit Paul Ferdinand M.
- Regecova Valeria
- Revilla Luis
- Ribas-Barba Lourdes
- Ribeiro Robespierre
- Riboli Elio
- Rigo Fernando
- Riley Leanne M.
- Rinaldo Natascia
- Rito Ana
- Ritti-Dias Raphael M.
- Rivera Juan A.
- Robitaille Cynthia
- Rodrigues Daniela
- Rodriguez-Artalejo Fernando
- Rodriguez-Martinez Andrea
- Rodriguez-Villamizar Laura A.
- Rojas-Martinez Rosalba
- Rojroongwasinkul Nipa
- Romaguera Dora
- Rosario Angelika Schaffrath
- Rosengren Annika
- Rouse Ian
- Roy Joel G. R.
- Rubinstein Adolfo
- Ruhli Frank J.
- Ruidavets Jean-Bernard
- Ruiz Moreno Emma
- Russo Paola
- Rust Petra
- Rutkowski Marcin
- Sabanayagam Charumathi
- Sachdev Harshpal S.
- Safiri Saeid
- Saidi Olfa
- Salanave Benoit
- Salazar-Martinez Eduardo
- Salmeron Diego
- Salomaa Veikko
- Salonen Jukka T.
- Salvetti Massimo
- Sanchez-Abanto Jose
- Sandjaja Sandjaja
- Sandra Ruiz-Betancourt Blanca
- Sans Susana
- Sant'Angelo Victoria Farrugia
- Santa-Marina Loreto
- Santos Sanz Sara
- Santos Silva Diego Augusto
- Santos Diana A.
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- Santos Rute
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- Sarrafzadegan Nizal
- Saum Kai-Uwe
- Savin Stefan
- Savva Savvas
- Savy Mathilde
- Scazufca Marcia
- Schargrodsky Herman
- Schienkiewitz Anja
- Schindler Karin
- Schipf Sabine
- Schmidt Carsten O.
- Schmidt Ida Maria
- Schoettker Ben
- Schultsz Constance
- Schutte Aletta E.
- Sebert Sylvain
- Sein Aye Aye
- Selamat Rusidah
- Sember Vedrana
- Sen Abhijit
- Senbanjo Idowu O.
- Sepanlou Sadaf G.
- Sequera Victor
- Serra-Majem Luis
- Servais Jennifer
- Shalnova Svetlana A.
- Sharma Sanjib K.
- Shaw Jonathan E.
- Shengelia Lela
- Shibuya Kenji
- Shimizu-Furusawa Hana
- Shin Dong Wook
- Shin Youchan
- Si-Ramlee Khairil
- Siani Alfonso
- Siantar Rosalynn
- Sibai Abla M.
- Silva Antonio M.
- Simon Mary
- Simons Judith
- Simons Leon A.
- Sjoberg Agneta
- Sjostrom Michael
- Slowikowska-Hilczer Jolanta
- Slusarczyk Przemyslaw
- Smeeth Liam
- Snijder Marieke B.
- So Hung-Kwan
- Sobngwi Eugene
- Soderberg Stefan
- Soekatri Moesijanti Y. E.
- Soemantri Agustinus
- Solfrizzi Vincenzo
- Solomon Bethlehem D.
- Son Thai Pham Son Thai Pham
- Sonestedt Emily
- Song Yi
- Sophiea Marisa K.
- Sorensen Thorkild I. A.
- Soric Maroje
- Soumare Aicha
- Spinelli Angela
- Spiroski Igor
- Staessen Jan A.
- Stamm Hanspeter
- Starc Gregor
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- Staub Kaspar
- Stavreski Bill
- Steene-Johannessen Jostein
- Stehle Peter
- Stein Aryeh D.
- Stergiou George S.
- Stessman Jochanan
- Stevens Gretchen A.
- Stocks Tanja
- Stoeckl Doris
- Stokwiszewski Jakub
- Stratton Gareth
- Stronks Karien
- Strufaldi Maria Wany
- Sturua Lela
- Suarez-Medina Ramon
- Sun Chien-An
- Sundstrom Johan
- Sung Yn-Tz
- Sunyer Jordi
- Suriyawongpaisal Paibul
- Swinburn Boyd A.
- Sy Rody G.
- Sylva Rene Charles
- Szponar Lucjan
- Taddei Cristina
- Tai Hing Lam Tai Hing Lam
- Tai E. Shyong
- Tammesoo Mari-Liis
- Tamosiunas Abdonas
- Tan Eng Joo
- Tang Xun
- Tanser Frank
- Tao Yong
- Tarawneh Mohammed Rasoul
- Tarp Jakob
- Tarqui-Mamani Carolina B.
- Taylor Anne
- Tchibindat Felicite
- Tebar William R.
- Tell Grethe
- Tello Tania
- Theobald Holger
- Theodoridis Xenophon
- Thijs Lutgarde
- Thuesen Betina H.
- Ticha Lubica
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- Tjonneland Anne
- Tolonen Hanna K.
- Tolstrup Janne S.
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- Tormo Maria Jose
- Tornaritis Michael J.
- Torrent Maties
- Toselli Stefania
- Traissac Pierre
- Tran Quoc Bao Tran Quoc Bao
- Trichopoulos Dimitrios
- Trichopoulou Antonia
- Trinh Oanh T. H.
- Trivedi Atul
- Tsao Yu-Hsiang
- Tshepo Lechaba
- Tsigga Maria
- Tsugane Shoichiro
- Tulloch-Reid Marshall K.
- Tullu Fikru
- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Turley Maria L.
- Tynelius Per
- Tzotzas Themistoklis
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice E.
- Ukoli Flora A. M.
- Ulmer Hanno
- Unal Belgin
- Uusitalo Hannu M. T.
- Vaitkeviciute Justina
- Valdivia Gonzalo
- Vale Susana
- Valvi Damaskini
- van der Schouw Yvonne T.
- Van Herck Koen
- van Rossem Lenie
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varela-Moreiras Gregorio
- Varona-Perez Patricia
- Vatten Lars
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Velika Biruta
- Veronesi Giovanni
- Verschuren W. M. Monique
- Victora Cesar G.
- Viegi Giovanni
- Viet Lucie
- Vineis Paolo
- Vioque Jesus
- Virtanen Jyrki K.
- Visser Marjolein
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
- Volzke Henry
- Voutilainen Ari
- Voutilainen Sari
- Vrijheid Martine
- Vrijkotte Tanja G. M.
- Vrkic Tajana Zeljkovic
- Wade Alisha N.
- Wagner Aline
- Waldhoer Thomas
- Walton Janette
- Wanderley Rildo S., Jr.
- Wang Ming-Dong
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Weber Adelheid
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Wiecek Andrzej
- Wijga Alet H.
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Wu Frederick C.
- Wu Jianfeng
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yngve Agneta
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O.
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A.
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhao Dong
- Zhao Wenhua
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zhussupov Baurzhan
- Zimmermann Esther
- Zuniga Cisneros Julio
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Abbas Rezaianzadeh
- Abdonas Tamosiunas
- Abdul Basit
- Abdul Hamid Zargar
- Abdullah Alkandari
- Abdullatif Husseini
- Abhijit Sen
- Abla M Sibai
- Abu Am Hanif
- Adela Chirita-Emandi
- Adelheid Weber
- Adetoyeje Y Oyeyemi
- Adewale L Oyeyemi
- Adolfo Rubinstein
- Adoubi Kassi Anicet
- Adroaldo Cesar Araujo Gaya
- Afshin Ostovar
- Agnes L Kadvan
- Agneta Sjöberg
- Agneta Yngve
- Agnès Le Port
- Agustinus Soemantri
- Agustín Perez-Londoño
- Ahmad A Zainuddin
- Ahmad Faudzi Yusoff
- Ahmad Reza Dorosty
- Ahmed A Madar
- Aida Pilav
- Aïcha Soumaré
- Akaninyene Otu
- Akihiro Yoshihara
- Akkumis Salhanova
- Akram Pourshams
- Ala'a Alkerwi
- Alain Morejon
- Alanna G da Silva
- Albertino Damasceno
- Alberto Barceló
- Alberto Palloni
- Albina A Fakhretdinova
- Alejandro Diaz
- Aleksander Giwercman
- Aleksandra Gomula
- Aleksandra Piwonska
- Alessandro Gialluisi
- Aletta E Schutte
- Alexander D Deev
- Alexandra M Cucu
- Alexandre C Pereira
- Alfonso Siani
- Alfonso Sousa-Poza
- Ali Ahmadi
- Ali Akbar Shayesteh
- Ali Esmaeili
- Ali Ghanbari
- Ali Reza Safarpour
- Alice Bonilla-Vargas
- Alicia Matijasevich
- Alina G Platonova
- Alina Kerimkulova
- Aline Meirhaeghe
- Aline P Batista
- Alireza Ansari-Moghaddam
- Alireza Khosravi
- Alireza Moslem
- Alireza Sadjadi
- Alisha N Wade
- Alison J Hayes
- Alison J Price
- Allan G Hill
- Allan Linneberg
- Almaz Sharman
- Altan Onat
- Aluisio Jd Barros
- Alun Evans
- Amalia De Curtis
- Amanda G Thrift
- Amanda J Cross
- Amaneh Shayanrad
- Ambady Ramachandran
- Amelia C Crampin
- Amina Barkat
- Amir Houshang Mehrparvar
- Amirabbas Momenan
- Ana Azevedo
- Ana B Crujeiras
- Ana Barradas-Pires
- Ana Carolina Mgn de Sá
- Ana D González-Alvarez
- Ana Henriques
- Ana I Rito
- Ana Jelaković
- Ana Maria B Menezes
- Ana P Ortiz
- Ana Paula C Cândido
- Anabela Mota-Pinto
- Anar Dushpanova
- Anastasia Markaki
- Anders Grøntved
- Andre L Guimaraes
- Andre P Kengne
- Andrea Gazzinelli
- Andrea Gualtieri
- Andrea Rodriguez-Martinez
- Andrea Rvr Horimoto
- Andrea Schneider
- Andrea Y Rodríguez
- Andrea Zentai
- Andreas Stang
- Andreia N Pizarro
- Andrew Kingston
- Andrew Reynolds
- Andrew Wong
- Andrzej Galbarczyk
- Andrzej Pająk
- Andrzej Więcek
- Anelise Reis Gaya
- Aneta Grajda
- Aneta Weres
- Anette Varbo
- Angel R Gonzalez
- Angela Chetrit
- Angela Döring
- Angela Spinelli
- Angelika Schaffrath Rosario
- Angelique Chan
- Angélica M Ochoa-Avilés
- Anie Marcil
- Anil Poudyal
- Anja L Madsen
- Anja Schienkiewitz
- Anna Bartosiewicz
- Anna Bugge
- Anna Fijalkowska
- Anna Jansson
- Anna V Alieva
- Annamari Lundqvist
- Anne A Bjerregaard
- Anne Chinnock
- Anne Juolevi
- Anne Taylor
- Anne Tjonneland
- Anneke Blokstra
- Annette J Dobson
- Annette Peters
- Annika Rosengren
- Anthony Kafatos
- Antonia Trichopoulou
- Antonio Bernabe-Ortiz
- Antonio Cabrera de León
- Antonio M Silva
- Antonio Mistretta
- Antonio Pedro Graça
- Antonio Prista
- Antonis Zampelas
- Antonisamy Belavendra
- Anu Mishra
- Anwar M Batieha
- Archie W Rayner
- Areti Triantafyllou
- Argyro Karakosta
- Ari Voutilainen
- Aristides M Machado-Rodrigues
- Arnaud Chiolero
- Aroor Bhagyalaxmi
- Arsalan Khaledifar
- Artur Mazur
- Arvind Pandey
- Arwa M Alshangiti
- Aryeh D Stein
- Asher Fawwad
- Attilio Rigotti
- Atul Trivedi
- Augustin F Beybey
- Augustine N Odili
- Augusto Di Castelnuovo
- Aung Soe Htet
- Ausra Petrauskiene
- Avula Laxmaiah
- Axel C Carlsson
- Aya Mostafa
- Ayman A Zayed
- Azaliia M Tuliakova
- Azhar Dyussupova
- Azim Nejatizadeh
- Azli Baharudin
- Åsa Ågren
- Badreya Al-Lahou
- Bagher Larijani
- Bahareh Kheiri
- Bahman Cheraghian
- Bakary Jallow
- Baltazar Nunes
- Barbara Heude
- Barbara Thorand
- Barry M Popkin
- Batyrbek Assembekov
- Beatriz D Schaan
- Bee Koon Poh
- Behrooz Hamzeh
- Bekbolat Zholdin
- Belgin Unal
- Belong Cho
- Ben Schöttker
- Benjamin Acosta-Cazares
- Benoit Salanave
- Benson M Kazembe
- Bente Sparboe-Nilsen
- Bernard Maire
- Bernardo L Horta
- Bernhard O Boehm
- Bert-Jan van den Born
- Bettina Bringolf-Isler
- Bharathi Viswanathan
- Bhawesh Koirala
- Bihungum Bista
- Bill Stavreski
- Bin Zhou
- Bing Zhang
- Birgit Linkohr
- Biruta Velika
- Blanca Sandra Ruiz-Betancourt
- Bo Werner
- Boban Mugoša
- Bogdan Wojtyniak
- Bojan Jelaković
- Bontha V Babu
- Boyd A Swinburn
- Börge Schmidt
- Branimir Leskošek
- Breige A McNulty
- Brian Oldenburg
- Brooklyn Fraser
- Bruna Gonçalves Cordeiro da Silva
- Buthaina M Alkhatib
- Børge G Nordestgaard
- Caleb Ochimana
- Calogero Saieva
- Calvin Ke
- Camilla T Damsgaard
- Carl Lachat
- Carla Menêses Hardman
- Carlo Maria Barbagallo
- Carlos A Aguilar-Salinas
- Carlos O Mendivil
- Carlos P Boissonnet
- Carmen Iñiguez
- Carolina B Tarqui-Mamani
- Caroline H Fall
- Caroline Ramos de Moura Silva
- Carsten O Schmidt
- Cassiano Ricardo Rech
- Catherine Kyobutungi
- Catterina Ferreccio
- Cecilia Björkelund
- Cecily Kelleher
- Cesar G Victora
- Cézane P Reuter
- Chandini Nekkantti
- Chao Qiang Jiang
- Charalambos A Hadjigeorgiou
- Charles Agyemang
- Charles K Mondo
- Charles Lunogelo
- Charles Sossa Jérome
- Charlie Lim
- Charlotte B Ottendahl
- Charmaine A Duante
- Charumathi Sabanayagam
- Chiara Donfrancesco
- Chien-An Sun
- Chien-Jen Chen
- Ching-Yu Cheng
- Chinh Nguyen Huu
- Chinwuba Ijoma
- Chongjian Wang
- Chris Cowell
- Christa L Lilly
- Christa Meisinger
- Christian Gieger
- Christina C Dahm
- Christina Howitt
- Christina Mavrogianni
- Christine Cameron
- Christophe Tzourio
- Christopher J Paciorek
- Chung T Nguyen
- Cihangir Erem
- Claes Ohlsson
- Clara Homs
- Claudia M Hormiga
- Cláudia S Minderico
- Clicerio González-Villalpando
- Clive Osmond
- Coimbatore Subramaniam Shanthirani
- Con Burns
- Constance Schultsz
- Constanta Huidumac Petrescu
- Cora L Craig
- Correia Júnior Marco Aurélio de Valois
- Cosmin R Cojocaru
- Cristina P Padez
- Crizian G Saar
- Cynthia M Pérez
- Cyrus Cooper
- Daan Kromhout
- Dalia Luksiene
- Damaskini Valvi
- Damian K Francis
- Dan Zhu
- Daniel Bia
- Daniel Fernández-Bergés
- Daniel Ferrante
- Daniel G Vasques
- Daniel Lemogoum
- Daniel Weghuber
- Daniela Galeone
- Daniela Kállayová
- Daniela Pierannunzio
- Daniela Rodrigues
- Daphne Lai
- Daphne Mirkopoulou
- David A Gonzalez-Chica
- David De Ridder
- David Faeh
- David Goltzman
- Davide Noto
- Davood Khalili
- Deborah C Malta
- Debra S Judge
- Deena Al Asfoor
- Deepak N Amarapurkar
- Delphine De Smedt
- Demetre Labadarios
- Denise Eldemire-Shearer
- Dermot O'Reilly
- Dénes Molnár
- Diana A Santos
- Diane T Meto
- Dianna J Magliano
- Dickman Gareta
- Diego Augusto Santos Silva
- Diego G Christofaro
- Diego Salmerón
- Diego Vanuzzo
- Dimitrios Papandreou
- Dimitrios Poulimeneas
- Dimitrios Trichopoulos
- Dirk De Bacquer
- Dirk Vanderschueren
- Dominique Cottel
- Dominique Hange
- Dong Zhao
- Dongfeng Gu
- Dora Romaguera
- Doris Stöckl
- Dorja Vocanec
- Doroteia A Höfelmann
- Dusko J Bjelica
- Dušan Grafnetter
- Duygu Islek
- Dwi Hapsari Tjandrarini
- E Shyong Tai
- Ebrahim Eftekhar
- Ebrahim Ghaderi
- Eduardo Capuano
- Eduardo Salazar Martinez
- Edward F Fottrell
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- Priscilla Duboz
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- Reecha Sofat
- Regina Heidinger-Felső
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- Ricky Eddie
- Rildo de Souza Wanderley Júnior
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- Robert Beaglehole
- Robert Eggertsen
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- Roberta B Caixeta
- Robespierre Ribeiro
- Rocco Capuano
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- Rodica Nicolescu
- Rodrigo M Carrillo-Larco
- Rody G Sy
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- Rohina Joshi
- Roman Topór-Mądry
- Romana Roccaldo
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- Ronald D Gregor
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- Ronit Endevelt
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- Rosa Haghshenas
- Rosalba Rojas-Martinez
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- Rosemarie Martin
- Rosie K Singleton
- Rossina G Pareja
- Rosu Maria-Magdalena
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- Ruan Kruger
- Rudolf Kaaks
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- Rusidah Selamat
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- Ruzena Kubinova
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- Sandjaja
- Sandra C Fuchs
- Sandra Colorado-Yohar
- Sania Nishtar
- Sanja Musić Milanović
- Sanja Šalaj
- Sanjay Rampal
- Sanjib K Sharma
- Santiago F Gómez
- Santosh K Bhargava
- Sara Magnacca
- Sara Schramm
- Sarah Cuschieri
- Sarah P Garnett
- Sare Safi
- Sareh Eghtesad
- Sari Hantunen
- Saskia Te Velde
- Satoko Sakata
- Sauli Herrala
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- Sergej M Ostojic
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- Seth Adu-Afarwuah
- Seyed Mohammad Hashemi-Shahri
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- Shahla AlDhukair
- Shaker A Alomary
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- Sheena E Ramsay
- Sheikh Mohammed Shariful Islam
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- Sherali Rakhmatulloev
- Sherilynn Madraisau
- Shina Avi
- Shiqi Zhen
- Shirin Djalalinia
- Shoaib Afzal
- Shoichiro Tsugane
- Shouling Wu
- Shu-Ti Chiou
- Shubash Ganapathy
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- Sigmund A Anderssen
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- Silvia Bel-Serrat
- Silvije Vuletić
- Simo Pone Larissa
- Simona Bo
- Simona Costanzo
- Simona Giampaoli
- Sinead Brophy
- Sirkka Keinänen-Kiukaanniemi
- Slavica Sovic
- Slawomir Koziel
- Snehalatha Chamukuttan
- Sofia K Malyutina
- Soheir H Ahmed
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- Solie Puhakka
- Son Thai Pham
- Songhomitra Panda-Jonas
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- Stefaan De Henauw
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- Stefan Adela Gabriela
- Stefan Kiechl
- Stefan Rach
- Stefan Savin
- Stefan Söderberg
- Stefania Maggi
- Stefania Toselli
- Stefano Marventano
- Steinar Krokstad
- Stephen T McGarvey
- Steve Botomba
- Stevo R Popovic
- Stig E Bojesen
- Stine Schramm
- Sudha Ramachandra Rao
- Sudhir Kowlessur
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- Teresa Shamah-Levy
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- Tomas Vega
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- Valirie N Agbor
- Valter Barbosa Filho
- Vanessa Rouzier
- Vanina Bongard
- Vasiliki Efthymiou
- Vassilis Zafiropulos
- Vayia Rarra
- Vedrana Sember
- Veikko Salomaa
- Vera Lanska
- Vera Musil
- Veronica Mocanu
- Vesna Juresa
- Vesselka L Duleva
- Victor M Herrera
- Victor Matsudo
- Victor Pf Lhoste
- Victoria E Soto-Rojas
- Victoria Farrugia Sant'Angelo
- Vijaya Lingam
- Viktoria Anna Kovacs
- Viktoriya Furdela
- Vilma E Irazola
- Vilma Kriaucioniene
- Vilmundur Gudnason
- Vilnis Dzerve
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- Vincenzo Solfrizzi
- Violeta Iotova
- Virginija Dulskiene
- Virgílio V Ramires
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- Viswanathan Mohan
- Viviana Guajardo
- Viviane C Cardoso
- Vladimir Kutsenko
- Wafaie W Fawzi
- Wan Mohamad Wan Bebakar
- Wan Nazaimoon Wan Mohamud
- Wei Zheng
- Wei-Cheng Lo
- Wei-Yen Lim
- Weili Yan
- Wen-Harn Pan
- Wenbin Wei
- Wendy Van Lippevelde
- Wenhua Zhao
- Wichai Aekplakorn
- Willem A Hanekom
- William A Neal
- William R Tebar
- Wilma M Hopman
- Winsome R Parnell
- Wm Monique Verschuren
- Wojciech Drygas
- Wojciech Rusek
- Wolfgang Ahrens
- Wolfgang Kratzer
- Xenophon Theodoridis
- Xiangjun Wang
- Xiaoguang Yang
- Xiaotian Liu
- Ximena Berrios Carrasola
- Xinyi Gwee
- Xiu-Hua Guo
- Xu Lin
- Xu Ma
- Xueling Sim
- Xun Tang
- Ya Xing Wang
- Yadlapalli S Kusuma
- Yajaira Briceño
- Yang Yang
- Yanhui Dong
- Yanina Zocalo
- Yanitsa V Zhecheva
- Yannis Manios
- Yanping Li
- Yemane Berhane
- Yeunsook Rho
- Yeva Movsesyan
- Yi Song
- Yi Zeng
- Yih Chung Tham
- Yiling J Cheng
- Yin Guo
- Ying-Wei Wang
- Yingfeng Zheng
- Yn-Tz Sung
- Yong Tao
- Yonghua Hu
- Yosef Farzi
- Yoto Yotov
- Youcef Laid
- Young-Ho Khang
- Yousef Saleh Khader
- Yu-Ling Yu
- Yuan He
- Yufang Bi
- Yuki Fujita
- Yulia Balanova
- Yuliya V Solovieva
- Yuna He
- Yunjiang Yu
- Yury P Nikitin
- Yves Kameli
- Yves Martin-Prevel
- Yvonne T van der Schouw
- Zahra Mohammadi
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zengchang Pang
- Zhamilya Battakova
- Zhamyila Usupova
- Zhanna Kalmatayeva
- Zhen-Yu Zhang
- Zhengming Chen
- Ziad A Abdeen
- Zivka Dika
- Zlatko Fras
- Zulfiqar A Bhutta
- Zulfiya Abdurrahmonova
- Zumin Shi
- Łukasz Kryst
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
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- Abdeen ZA
- Abdrakhmanova S
- Abu-Rmeileh NM
- Acosta-Cazares B
- Adams RJ
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- Zhussupov B
- Zimmermann E
- Zuniga Cisneros J
- Publication venue
- NATURE PUBLISHING GROUP
- Publication date
- 09/05/2019
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity. Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017—and more than 80% in some low- and middle-income regions—was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing—and in some countries reversal—of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Aarestrup J
- Abarca-Gomez L
- Abbasi-Kangevari M
- Abdeen ZA
- Abdrakhmanova S
- Abdurrahmonova Z
- Abril GL
- Abu-Rmeileh NM
- Acosta-Cazares B
- Adam I
- Adamczyk M
- Adams RJ
- Adu-Afarwuah S
- Aekplakorn W
- Afsana K
- Afzal S
- Agbor VN
- Agdeppa IA
- Aghazadeh-Attari J
- Agren A
- Aguenaou H
- Aguilar-Salinas CA
- Aguilar-Salinas CA
- Agyemang C
- Ahmad MH
- Ahmad NA
- Ahmadi A
- Ahmadi N
- Ahmadi N
- Ahmed I
- Ahmed SH
- Ahrens W
- Aitmurzaeva G
- Ajlouni K
- Al Asfoor D
- Al Hourani HM
- Al Nsour M
- Al Qaoud NM
- Al-Hazzaa HM
- Al-Hinai H
- Al-Lahou B
- Al-Lawati JA
- Al-Raddadi R
- Alarouj M
- AlBuhairan F
- AlDhukair S
- Aldwairji MA
- Alexius S
- Ali MM
- Alieva AV
- Alkandari A
- Alkerwi A
- Alkhatib BM
- Allin K
- Alomary SA
- Alomirah HF
- Alshangiti AM
- Alvarez-Pedrerol M
- Aly E
- Amarapurkar DN
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- Anderssen SA
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- Vasques DG
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- Yiallouros PK
- Yngve A
- Yoosefi M
- Yoshihara A
- Yotov Y
- You QS
- You S-L
- Younger-Coleman NO
- Yu Y
- Yu Y-L
- Yusof SM
- Yusoff AF
- Yusoff MFM
- Zaccagni L
- Zafiropulos V
- Zainuddin AA
- Zakavi SR
- Zamani F
- Zambon S
- Zampelas A
- Zamrazilova H
- Zapata ME
- Zargar AH
- Zaw KK
- Zayed AA
- Zdrojewski T
- Zeglen M
- Zejglicova K
- Zeng Y
- Zentai A
- Zhang B
- Zhang L
- Zhang Z-Y
- Zhao D
- Zhao M-H
- Zhao W
- Zhecheva YV
- Zhen S
- Zheng W
- Zheng Y
- Zholdin B
- Zhou B
- Zhou M
- Zhu D
- Zimmet P
- Zins M
- Zitt E
- Zocalo Y
- Zoghlami N
- Zuziak M
- Publication venue
- Elsevier
- Publication date
- 01/01/2024
- Field of study
Background
Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods
We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median).
Findings
From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness.
Interpretation
The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity.
Funding
UK Medical Research Council, UK Research and Innovation (Research England), UK Research and Innovation (Innovate UK), and European Union
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
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- Publication venue
- Publication date
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3�6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55 of the global rise in mean BMI from 1985 to 2017�and more than 80 in some low- and middle-income regions�was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing�and in some countries reversal�of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories. © 2019, The Author(s)
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
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- You QS
- You S-L
- Younger-Coleman NO
- Yu Y
- Yu Y-L
- Yusof SM
- Yusoff AF
- Yépez García M
- Zaccagni L
- Zafiropulos V
- Zainuddin AA
- Zakavi SR
- Zamani F
- Zambon S
- Zampelas A
- Zamrazilová H
- Zapata ME
- Zargar AH
- Zaw KK
- Zayed AA
- Zdrojewski T
- Zejglicova K
- Zeljkovic Vrkic T
- Zeng Y
- Zentai A
- Zhang B
- Zhang L
- Zhang Z-Y
- Zhao D
- Zhao M-H
- Zhao W
- Zhecheva YV
- Zhen S
- Zheng W
- Zheng Y
- Zholdin B
- Zhou B
- Zhou M
- Zhu D
- Zimmet P
- Zins M
- Zitt E
- Zocalo Y
- Zoghlami N
- Zuziak M
- Zuñiga Cisneros J
- Ängquist L
- Ågren Å
- Čapková N
- Łuszczki E
- Šalaj S
- Ševčíková Ľ
- Żegleń M
- Publication venue
- Elsevier
- Publication date
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining https://researchonline.ljmu.ac.uk/images/research_banner_face_lab_290.jpgunderweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity