171 research outputs found
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
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- Aloisio A
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- Woudstra MJ
- Wraight K
- Wright C
- Wright D
- Wright M
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wunstorf R
- Wynne BM
- Xaplanteris L
- Xella S
- Xie S
- Xie Y
- Xu C
- Xu D
- Xu G
- Yabsley B
- Yacoobb S
- Yagci KD
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamaoka J
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang UK
- Yang Y
- Yang Y
- Yang Z
- Yanush S
- Yao Y
- Yasu Y
- Ye J
- Ye S
- Yildizb HD
- Yilmaz M
- Yoosootiniya R
- Yorita K
- Yoshida R
- Young C
- Youssef S
- Yu D
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zaets VG
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zalite YK
- Zanello L
- Zarzhitsky P
- Zaytsev A
- Zeitnitz C
- Zeller M
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenonos Z
- Zenz S
- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang Q
- Zhang X
- Zhang Z
- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Ebola: translational science considerations
- Author
- A Aguzzi
- A Anderson
- A Ansari
- A Barkhordarian
- A Barkhordarian
- A Barkhordarian
- A Ding
- A Jäger
- A Lakoff
- A Minagar
- A Takada
- AB Roberts
- AH Ding
- Allison L Jan
- AM Nading
- AM Nyamathi
- Andre Bakhordarian
- Angela M Du
- April D Thames
- AS Rosenthal
- BA Beutler
- BL Hewlett
- BM Assas
- BS Hewlett
- BS Hewlett
- BS Hewlett
- BT Hawkins
- C Beste
- C Caduff
- C Lynteris
- C Porta
- C Tacchetti
- C Tan
- CA Chapman
- CA Janeway
- CA Zampieri
- Carl A Maida
- CD Mills
- CD Mills
- CD Mills
- CE Rupprecht
- CF Nathan
- CH Ries
- CJ Wilson
- CL Hunt
- CR Janes
- CR Plata-Salamán
- CS Hsieh
- CS Ramanathan
- CT Ekdahl
- D Davalos
- D Galimberti
- D Gatherer
- DG Alleva
- DG Bausch
- DG Bausch
- DG DeNardo
- DI Gabrilovich
- DJ Alcendor
- DJ Stuehr
- DM Hermann
- DM Mosser
- DV Clark
- DW Leung
- E Gonzalez
- EA Eugenin
- Editorial
- EH Wilson
- EL Cooper
- EM Leroy
- EM Leroy
- Ercolano Manfrini
- F Chiappelli
- F Chiappelli
- FA Murphy
- Francesco Chiappelli
- Francesco Piva
- G Bediang
- G Gehring
- G Wong
- G Wu
- GA Aarons
- GD Maganga
- GJ Armelagos
- H Bour-Jordan
- H Bour-Jordan
- H Brown
- H Feldmann
- H Liang
- H Mu
- H Nakajima
- HG Williams-Ashman
- HL Janssen
- I Harper
- IM Corraliza
- J Kinsman
- J Li
- J MacMicking
- J Pettitt
- J Preston
- J Wamala
- JA Wilson
- JB Hibbs
- JB Hibbs
- JD Shearer
- JH Choi
- JH Kuhn
- JJ Donegan
- JM Dzik
- JM Krueger
- JN Abbott
- JP Gonzalez
- JW Moncrief
- K Conant
- K Pandjassarame
- K Stark
- KL Warfield
- KT Kreiter
- L Cassetta
- L Charles
- L Han
- LE Bermudez
- LG Barrientos
- LJ Berg
- LR Ferguson
- M Bray
- M Erta
- M Garcia-Calvo
- M Gupta
- M Leach
- M Leach
- M McCarthy
- M Mitka
- M Modolell
- M Munder
- M Nekludov
- M Pardridge
- M Pepper
- M Rock
- M Sheng
- M Singer
- M Toborek
- M Uguccioni
- M Weidmann
- MB Graeber
- MC Papadopoulos
- Melissa Nahcivan
- MF Almeida
- MH Lehmann
- MI Meltzer
- Mia T Nguyen
- MJ Almeida de
- MO Pulina
- MP Muehlenbein
- N Komatsu
- N Romo
- N Wauquier
- Nateli Sama
- NJ Abbott
- NK Jerne
- NL Sparkman
- NP Whitney
- O Martinez
- P Calain
- P Daszak
- P Daszak
- P Farmer
- P Formenty
- P Muranski
- P Puddu
- P Ramanan
- P Roddy
- PA Deverka
- PJ Brown
- PJ Murray
- PS Gill
- R Barrett
- R Hussain
- R Rutschman
- Rafael Rocha
- RB Stevens
- RJ Whitley
- RK Assoian
- RK Jangra
- RM Anthony
- S Bauer
- S Garamszegi
- S Mahanty
- S Tsunawaki
- SB Bradfute
- SB Bradfute
- SE Kauder
- SE Macatonia
- SK Gire
- SL Letendre
- SM Morris
- SM Morris
- SP Fisher-Hoch
- SP Shetty
- T Baune
- T Giles-Vernick
- T Hoenen
- T Kawai
- T Lawrence
- T Raeymakers
- T Scharton-Kersten
- TB McCall
- TW Geisbert
- V Bihrer
- V Boutard
- VM Wahl-Jensen
- W Kelder
- X Qiu
- Y Suzuki
- Y Yao
- Z Toossi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
We are currently in the midst of the most aggressive and fulminating outbreak of Ebola-related disease, commonly referred to as “Ebola”, ever recorded. In less than a year, the Ebola virus (EBOV, Zaire ebolavirus species) has infected over 10,000 people, indiscriminately of gender or age, with a fatality rate of about 50%. Whereas at its onset this Ebola outbreak was limited to three countries in West Africa (Guinea, where it was first reported in late March 2014, Liberia, where it has been most rampant in its capital city, Monrovia and other metropolitan cities, and Sierra Leone), cases were later reported in Nigeria, Mali and Senegal, as well as in Western Europe (i.e., Madrid, Spain) and the US (i.e., Dallas, Texas; New York City) by late October 2014. World and US health agencies declared that the current Ebola virus disease (EVD) outbreak has a strong likelihood of growing exponentially across the world before an effective vaccine, treatment or cure can be developed, tested, validated and distributed widely. In the meantime, the spread of the disease may rapidly evolve from an epidemics to a full-blown pandemic. The scientific and healthcare communities actively research and define an emerging kaleidoscope of knowledge about critical translational research parameters, including the virology of EBOV, the molecular biomarkers of the pathological manifestations of EVD, putative central nervous system involvement in EVD, and the cellular immune surveillance to EBOV, patient-centered anthropological and societal parameters of EVD, as well as translational effectiveness about novel putative patient-targeted vaccine and pharmaceutical interventions, which hold strong promise, if not hope, to curb this and future Ebola outbreaks. This work reviews and discusses the principal known facts about EBOV and EVD, and certain among the most interesting ongoing or future avenues of research in the field, including vaccination programs for the wild animal vectors of the virus and the disease from global translational science perspective
Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database
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- Aisa Tm
- Aisiku I
- Ajetunmobi Oo
- Aker M
- Akyol Oo
- Al Dorzi Hm
- Al Jabbary As
- Albaiceta Gm
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- Albiero D
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- Seoane-Quiroga L
- Serra C
- Serra Im
- Setten Mg
- Seven A
- Shah B
- Shao H
- Shen J
- Shenoy A
- Sher S
- Shimizu K
- Shindhe S
- Shinn Iii Jo
- Shiozaki K
- Silesky Jimenez Ji
- Silesky J
- Sim M
- Simon P
- Simonis Fd
- Sivashanmugavel M
- Sjøbø Bå
- Sklienka P
- Smith Mj
- Smith O
- Soler Ja
- Solis-Quesada Je
- Sottiaux T
- Souissi Ab
- Spadaro S
- Srinivasa L
- Stamou Ee
- Staudinger T
- Stephenson L
- Stewart R
- Stigler W
- Strauch U
- Sula H
- Sun R
- Surbatovic M
- Suzuki H
- Symmonds S
- Synclair J
- Szakmany T
- Sánchez Rm
- Sánchez-Ballesteros J
- Søreide E
- Tabhan E
- Tabhan Ee
- Tainter C
- Takaba A
- Takada T
- Takagi S
- Tallet Alfonso Aa
- Tan Bc
- Tanaka H
- Tang R
- Tapponnier R
- Tarantino F
- Temprano S
- Terzi N
- Thibault S
- Thompson B. Taylor
- Thompson Mm
- Tibblin Ao
- Tinnirello A
- Tiribelli N
- Todeschini M
- Tomescu Dr
- Toribio Dp
- Toth-Tarsoly P
- Treanor N
- Trinidad Oa
- Tulaimat A
- Twohey L
- Uchiyama A
- Ueda T
- Ueno K
- Umbrello M
- Unnikrishnan R
- Uppalapati A
- Van Haren F
- Van Wezel Hm
- Vargas Mp
- Vascotto Er
- Vasquez Dn
- Vega Ld
- Veljovic M.
- Venti A
- Vercueil A
- Vermassen J
- Verstraete R
- Villagomez A
- Villagomez Aj
- Villamagua Bg
- Villar V
- Virgilio Cg
- Vitale Mn
- Volta Ca
- Wang C
- Wang Hx
- Wang Sh
- Wang W
- Warren J
- Watanabe E
- Watt P
- Welters Id
- Wenham T
- Wessbergh J
- Whitehead C
- Willett El
- Williams Aj
- Williams Ke
- Wise Mp
- Wittebole X
- Wong Hs
- Woods Pw
- Wrathall Dw
- Wrigge H
- Wu Yq
- Xin-Hua Q
- Xu Y
- Yamaguchi O
- Yamaji Y
- Yao Q
- Ye Zl
- Yeatts Dj
- Yu R
- Yu T
- Yu W
- Yumha Js
- Yuste Lj
- Zacharas Ga
- Zacharowski Kd
- Zani G
- Zantua Ks
- Zazu A
- Zeggwagh Aa
- Zeggwagh Aa
- Zein So
- Zender Ho
- Zhai Z
- Zhang F
- Zhang Xy
- Zhao H
- Zhao J
- Zhao Xy
- Zheng R
- Zhou Fc
- Zhou S
- Zhu Bh
- Zhu Wh
- Zogheib Eh
- Ñamendys-Silva Sa
- Ünal N
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The objective of this study was to evaluate associations between pre-existing diabetes mellitus and ARDS in critically ill patients with acute hypoxemic respiratory failure (AHRF). Methods: An ancillary analysis of a global, multi-centre prospective observational study (LUNG SAFE) was undertaken. LUNG SAFE evaluated all patients admitted to an intensive care unit (ICU) over a 4-week period, that required mechanical ventilation and met AHRF criteria. Patients who had their AHRF fully explained by cardiac failure were excluded. Important clinical characteristics were included in a stepwise selection approach (forward and backward selection combined with a significance level of 0.05) to identify a set of independent variables associated with having ARDS at any time, developing ARDS (defined as ARDS occurring after day 2 from meeting AHRF criteria) and with hospital mortality. Furthermore, propensity score analysis was undertaken to account for the differences in baseline characteristics between patients with and without diabetes mellitus, and the association between diabetes mellitus and outcomes of interest was assessed on matched samples. Results: Of the 4107 patients with AHRF included in this study, 3022 (73.6%) patients fulfilled ARDS criteria at admission or developed ARDS during their ICU stay. Diabetes mellitus was a pre-existing co-morbidity in 913 patients (22.2% of patients with AHRF). In multivariable analysis, there was no association between diabetes mellitus and having ARDS (OR 0.93 (0.78-1.11); p = 0.39), developing ARDS late (OR 0.79 (0.54-1.15); p = 0.22), or hospital mortality in patients with ARDS (1.15 (0.93-1.42); p = 0.19). In a matched sample of patients, there was no association between diabetes mellitus and outcomes of interest. Conclusions: In a large, global observational study of patients with AHRF, no association was found between diabetes mellitus and having ARDS, developing ARDS, or outcomes from ARDS. Trial registration: NCT02010073. Registered on 12 December 2013
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study
- Author
- Abad RD
- Abe T
- Abroug F
- Adams JC
- Adamsson RO
- Adolfsson A
- Aguilar RZ
- Aguirre JS
- Aguirre-Bermeo H
- Aisa TM
- Aisiku I
- Ajetunmobi OO
- Aker M
- Akyol OO
- Al Dorzi HM
- Al Jabbary AS
- Albaiceta GM
- Albarrak MM
- Albiero D
- Alda RS
- Alejandro RV
- Alexander P
- Algaba Á
- Aliaga FA
- Alisasis AU
- Allan RM
- Allue RM
- Almekhlaf G
- Alonso JG
- Altaf W
- Alvarez AM
- Alvarez J
- Amin P
- Amir F
- Amor M
- An Y
- Andersen FH
- Andoh K
- Andruszkiewicz P
- Aneman A
- Antonelli MM
- Antônio ACP
- Aoki N
- Appelberg H
- Arabi Y
- Arabi YM
- Araujo AM
- Arizmendi A
- Arnal JM
- Artiga MJD
- Artigas A
- Ascoli A
- Au SM
- Avila LE
- Azad R
- Azevedo LC
- Baboi L
- Badie JC
- Bailey IM
- Bailey MB
- Bajwa E
- Balkhi H
- Baltus T
- Banner-Goodspeed VM
- Barberet G
- Baron RM
- Baronia AK
- Barratt-Due A
- Barros FM
- Barros NC
- Batra H
- Battle CE
- Bauer PR
- Beck E
- Beck O
- Bedreag OH
- Beegle SH
- Beitler JR
- Bellani G
- Bellani G.
- Beloncle F
- Ben Souissi A
- Benslama A
- Beraldo DO
- Berghe C
- Berkelmans F
- Besset SL
- Bettini LR
- Beuret P
- Bezzi MG
- Bhardwaj VK
- Bhowmick K
- Biehler J
- Bigot C
- Bihari S
- Biondi RS
- Biscione RR
- Bisso MC
- Black CS
- Blakeman TC
- Blanco J
- Bolon S
- Borello SA
- Borotto EE
- Botteri M
- Bouchoucha S
- Boukhazna M
- Bouw MJ
- Boyd O
- Bramall J
- Braschi A
- Brazzi L
- Breen DM
- Briquet A
- Brito VA
- Brizuela M
- Brochard L
- Brochard L.
- Broman LM
- Brown SM
- Browne TS
- Bruhn AR
- Brunettini B
- Bruns MM
- Buensuseso JA
- Bugedo G
- Buise MP
- Bulpa PA
- Bumbasierevic V
- Bumbasirevic V
- Burtenshaw AJ
- Burtin P
- Buzancais G
- Béduneau G
- Camsooksai J
- Canestrini S
- Cani A
- Carbayo-Gorriz C
- Cardonnet LP
- Careless JP
- Carpentier D
- Carreño NG
- Carteaux G
- Casalena P
- Casement J
- Castro AG
- Castro S
- Catorze NT
- Cazorla-Barranquero FG
- Ceniceros-Barros A
- Cereijo E
- Cerny V
- Cerrato VI
- Cesar PS
- Ceunen H
- Ceylan I
- Chabanne R
- Chapman R
- Chau SK
- Chelly J
- Chen K
- Chena A
- Cheng MP
- Chiche JD
- Chouchene I
- Choudry S
- Christiansen A
- Cimic N
- Cinnella G
- Cirone R
- Citalán JE
- Claraco-Vega LM
- Clarkson K
- Clarkson KP
- Claverias L
- Cohen JE
- Cole JM
- Collins DV
- Collyer T
- Colombo R
- Combaux DM
- Combes A
- Cooper R
- Coppadoro A
- Corneci DE
- Cortegiani A
- Cortez CA
- Coxo CM
- Cracchiolo AN
- Cranshaw JH
- Crapelli G
- Crouch DR
- Crova PJ
- Csabi P
- Curley G
- Curto EG
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- Dangers L
- Danin PE
- Daubin C
- Daviaud F
- Davies KG
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- De Gordoa LO
- De Haro C
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- Declercq PM
- Dector D
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- Dellera C
- Delsing A
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- Labarca EF
- Laffey J
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- Laffey JG
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- Silesky Jimenez JI
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- Spadaro S
- Srinivasa L
- Stamou EE
- Staudinger T
- Stephenson L
- Stewart R
- Stigler W
- Strauch U
- Sula H
- Sun R
- Surbatovic M
- Suzuki H
- Szakmany T
- Sánchez RM
- Sánchez-Ballesteros J
- Søreide E
- Tabhan E
- Tabhan EE
- Tainter C
- Takaba A
- Takada T
- Takagi S
- Tallet Alfonso AA
- Tan BC
- Tanaka H
- Tang R
- Tapponnier R
- Tarantino F
- Temprano S
- Terzi N
- Thibault S
- Thomas M
- Thompson BT
- Thompson MM
- Tibblin AO
- Tinnirello A
- Tiribelli N
- Todeschini M
- Tomescu DR
- Toribio DP
- Toth-Tarsoly P
- Treanor N
- Trinder TJ
- Trinidad OA
- Tulaimat A
- Twohey L
- Uchiyama A
- Ueda T
- Ueno K
- Umbrello M
- Unnikrishnan R
- Uppalapati A
- van Haren F
- van Haren F.
- Van Wezel HM
- Vargas MP
- Vascotto ER
- Vasquez DN
- Vega LD
- Veljovic M.
- Venti A
- Vercueil A
- Vermassen J
- Verstraete R
- Villagomez A
- Villagomez AJ
- Villamagua BG
- Villar V
- Vinzio M
- Virgilio CG
- Vitale MN
- Volta CA
- Wang C
- Wang HX
- Wang SH
- Wang W
- Warren J
- Watanabe E
- Watt P
- Welters ID
- Wenham T
- Wessbergh J
- Whitehead C
- Willett EL
- Williams AJ
- Williams KE
- Wise MP
- Wittebole X
- Wong HS
- Woods PW
- Wrathall DW
- Wrigge H
- Wrigge H
- Wrigge H.
- Wu YQ
- Xin-Hua Q
- Xu Y
- Yamaguchi O
- Yamaji Y
- Yao Q
- Ye ZL
- Yeatts DJ
- Yu R
- Yu T
- Yu W
- Yumha JS
- Yuste LJ
- Zacharas GA
- Zacharowsk KD
- Zani G
- Zantua KS
- Zazu A
- Zeggwagh AA
- Zeggwagh AA
- Zein SO
- Zender HO
- Zhai Z
- Zhang F
- Zhang XY
- Zhao H
- Zhao J
- Zhao XY
- Zheng R
- Zhou FC
- Zhou S
- Zhu BH
- Zhu WH
- Zogheib EH
- Ñamendys-Silva SA
- Ünal N
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2019
- Field of study
OBJECTIVES: To describe the characteristics and outcomes of patients with acute respiratory distress syndrome with or without spontaneous breathing and to investigate whether the effects of spontaneous breathing on outcome depend on acute respiratory distress syndrome severity. DESIGN: Planned secondary analysis of a prospective, observational, multicentre cohort study. SETTING: International sample of 459 ICUs from 50 countries. PATIENTS: Patients with acute respiratory distress syndrome and at least 2 days of invasive mechanical ventilation and available data for the mode of mechanical ventilation and respiratory rate for the 2 first days. INTERVENTIONS: Analysis of patients with and without spontaneous breathing, defined by the mode of mechanical ventilation and by actual respiratory rate compared with set respiratory rate during the first 48 hours of mechanical ventilation. MEASUREMENTS AND MAIN RESULTS: Spontaneous breathing was present in 67% of patients with mild acute respiratory distress syndrome, 58% of patients with moderate acute respiratory distress syndrome, and 46% of patients with severe acute respiratory distress syndrome. Patients with spontaneous breathing were older and had lower acute respiratory distress syndrome severity, Sequential Organ Failure Assessment scores, ICU and hospital mortality, and were less likely to be diagnosed with acute respiratory distress syndrome by clinicians. In adjusted analysis, spontaneous breathing during the first 2 days was not associated with an effect on ICU or hospital mortality (33% vs 37%; odds ratio, 1.18 [0.92-1.51]; p = 0.19 and 37% vs 41%; odds ratio, 1.18 [0.93-1.50]; p = 0.196, respectively ). Spontaneous breathing was associated with increased ventilator-free days (13 [0-22] vs 8 [0-20]; p = 0.014) and shorter duration of ICU stay (11 [6-20] vs 12 [7-22]; p = 0.04). CONCLUSIONS: Spontaneous breathing is common in patients with acute respiratory distress syndrome during the first 48 hours of mechanical ventilation. Spontaneous breathing is not associated with worse outcomes and may hasten liberation from the ventilator and from ICU. Although these results support the use of spontaneous breathing in patients with acute respiratory distress syndrome independent of acute respiratory distress syndrome severity, the use of controlled ventilation indicates a bias toward use in patients with higher disease severity. In addition, because the lack of reliable data on inspiratory effort in our study, prospective studies incorporating the magnitude of inspiratory effort and adjusting for all potential severity confounders are required
Epidemiology and patterns of tracheostomy practice in patients with acute respiratory distress syndrome in ICUs across 50 countries
- Author
- Abad RD
- Abe T
- Abe T.
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- Adams JC
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- Ñamendys-Silva SA
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS recruited into the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG-SAFE) study. Methods: This is a secondary analysis of LUNG-SAFE, an international, multicenter, prospective cohort study of patients receiving invasive or noninvasive ventilation in 50 countries spanning 5 continents. The study was carried out over 4 weeks consecutively in the winter of 2014, and 459 ICUs participated. We evaluated the clinical characteristics, management and outcomes of patients that received tracheostomy, in the cohort of patients that developed ARDS on day 1-2 of acute hypoxemic respiratory failure, and in a subsequent propensity-matched cohort. Results: Of the 2377 patients with ARDS that fulfilled the inclusion criteria, 309 (13.0%) underwent tracheostomy during their ICU stay. Patients from high-income European countries (n = 198/1263) more frequently underwent tracheostomy compared to patients from non-European high-income countries (n = 63/649) or patients from middle-income countries (n = 48/465). Only 86/309 (27.8%) underwent tracheostomy on or before day 7, while the median timing of tracheostomy was 14 (Q1-Q3, 7-21) days after onset of ARDS. In the subsample matched by propensity score, ICU and hospital stay were longer in patients with tracheostomy. While patients with tracheostomy had the highest survival probability, there was no difference in 60-day or 90-day mortality in either the patient subgroup that survived for at least 5 days in ICU, or in the propensity-matched subsample. Conclusions: Most patients that receive tracheostomy do so after the first week of critical illness. Tracheostomy may prolong patient survival but does not reduce 60-day or 90-day mortality. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013
Measurement of the cross-section for b-jets produced in association with a Z boson at root s=7 TeV with the ATLAS detector ATLAS Collaboration
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- Zhemchugov A
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- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
A measurement is presented of the inclusive cross-section for b-jet production in association with a Z boson in pp collisions at a centre-of-mass energy of root s = 7 TeV. The analysis uses the data sample collected by the ATLAS experiment in 2010, corresponding to an integrated luminosity of approximately 36 pb(-1). The event selection requires a Z boson decaying into high P-T electrons or muons, and at least one b-jet, identified by its displaced vertex, with transverse momentum p(T) > 25 GeV and rapidity vertical bar y vertical bar < 2.1. After subtraction of background processes, the yield is extracted from the vertex mass distribution of the candidate b-jets. The ratio of this cross-section to the inclusive Z cross-section (the average number of b-jets per Z event) is also measured. Both results are found to be in good agreement with perturbative QCD predictions at next-to-leading order
Search for pairs of highly collimated photon-jets in pp collisions at √s = 13 TeV with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abhayasinghe DK
- Abidi SH
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- Yildiz H Duran
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- Zhao X
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- Zhao Z
- Zhemchugov A
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- Zhu CG
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- Zhuang X
- Zhukov K
- Zhulanov V
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Zinser M
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen H Meyer
- Zur Nedden M
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/08/2018
- Field of study
Results of a search for the pair production of photon-jets—collimated groupings of photons—in the ATLAS detector at the Large Hadron Collider are reported. Highly collimated photon-jets can arise from the decay of new, highly boosted particles that can decay to multiple photons collimated enough to be identified in the electromagnetic calorimeter as a single, photonlike energy cluster. Data from proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 36.7 fb−1, were collected in 2015 and 2016. Candidate photon-jet pair production events are selected from those containing two reconstructed photons using a set of identification criteria much less stringent than that typically used for the selection of photons, with additional criteria applied to provide improved sensitivity to photon-jets. Narrow excesses in the reconstructed diphoton mass spectra are searched for. The observed mass spectra are consistent with the Standard Model background expectation. The results are interpreted in the context of a model containing a new, high-mass scalar particle with narrow width, X, that decays into pairs of photon-jets via new, light particles, a. Upper limits are placed on the cross section times the product of branching ratios σ×B(X→aa)×B(a→γγ)2 for 200 GeV<mX<2 TeV and for ranges of ma from a lower mass of 100 MeV up to between 2 and 10 GeV, depending upon mX. Upper limits are also placed on σ×B(X→aa)×B(a→3π0)2 for the same range of mX and for ranges of ma from a lower mass of 500 MeV up to between 2 and 10 GeV
Search for dark matter produced in association with a single top quark or a top quark pair in proton-proton collisions at s=13 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WAT Wan
- Abdullin S
- Abdulsalam A
- Abercrombie D
- Abu Zeid S
- Ackert A
- Acosta D
- Acosta JG
- Adam W
- Adams MR
- Adams T
- Adzic P
- Afanasiev S
- Agapitos A
- Agaras MN
- Aggleton R
- Agram J-L
- Ahmad A
- Ahmad M
- Ahmad M
- Ahmed I
- Ahuja S
- Akbiyik M
- Akchurin N
- Akgun B
- Al-Bataineh A
- Albajar C
- Albergo S
- Albert A
- Albrow M
- Alcaraz Maestre J
- Aleksandrov A
- Alexander J
- Alhusseini M
- Ali MAB Md
- Alimena J
- Allen B
- Almond J
- Alvarez Fernandez A
- Alvarez JD Ruiz
- Alverson G
- Alves FL
- Alves GA
- Alyari M
- Amapane N
- Ambrogi F
- Amendola C
- Amin N
- Amsler C
- Anagnostou G
- Anampa K Hurtado
- Anderson D
- Andrea J
- Andreev V
- Andreev Yu
- Andrews MB
- Androsov K
- Angioni L Pinna
- Antonelli L
- Antropov I
- Antunovic Z
- Apanasevich L
- Apollinari G
- Apresyan A
- Apyan A
- Araujo M
- Arcaro D
- Arcidiacono R
- Arenton MW
- Argiro S
- Arndt T
- Arneodo M
- Asavapibhop B
- Asawatangtrakuldee C
- Asghar MI
- Asilar E
- Askew A
- Assran Y
- Atakisi IO
- Ather MW
- Attikis A
- Auffray E
- Aushev T
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avila C
- Ayala E
- Azarkin M
- Azhgirey I
- Aziz T
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- Azzolini V
- Azzurri P
- Baarmand MM
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- Bachiller I
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- Baden A
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- Baillon P
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- Bakhshiansohi H
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- Ball AH
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- Banerjee S
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- Bani L
- Bansal S
- Barbagli G
- Barberis E
- Bargassa P
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- Beaudette F
- Becerra DA Sanz
- Beernaert K
- Beghin D
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- Behnke O
- Behrens U
- Bein S
- Beirao Da Cruz E Silva C
- Belchior Batista Das Chagas E
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- Publication venue
- Publication date
- 01/01/2019
- Field of study
A search has been performed for heavy resonances decaying to ZZ or ZW in 2l2q final states, with two charged leptons (l = e, mu) produced by the decay of a Z boson, and two quarks produced by the decay of a W or Z boson. The analysis is sensitive to resonances with masses in the range from 400 to 4500 GeV. Two categories are defined based on the merged or resolved reconstruction of the hadronically decaying vector boson, optimized for high- and low-mass resonances, respectively. The search is based on data collected during 2016 by the CMS experiment at the LHC in proton-proton collisions with a center-of-mass energy of root s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). No excess is observed in the data above the standard model background expectation. Upper limits on the production cross section of heavy, narrow spin-1 and spin-2 resonances are derived as a function of the resonance mass, and exclusion limits on the production of W' bosons and bulk graviton particles are calculated in the framework of the heavy vector triplet model and warped extra dimensions, respectively.A search has been performed for heavy resonances decaying to ZZ or ZW in 2l2q final states, with two charged leptons (l = e, mu) produced by the decay of a Z boson, and two quarks produced by the decay of a W or Z boson. The analysis is sensitive to resonances with masses in the range from 400 to 4500 GeV. Two categories are defined based on the merged or resolved reconstruction of the hadronically decaying vector boson, optimized for high- and low-mass resonances, respectively. The search is based on data collected during 2016 by the CMS experiment at the LHC in proton-proton collisions with a center-of-mass energy of root s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1). No excess is observed in the data above the standard model background expectation. Upper limits on the production cross section of heavy, narrow spin-1 and spin-2 resonances are derived as a function of the resonance mass, and exclusion limits on the production of W' bosons and bulk graviton particles are calculated in the framework of the heavy vector triplet model and warped extra dimensions, respectively.A search for dark matter produced in association with top quarks in proton-proton collisions at a center-of-mass energy of 13 TeV is presented. The data set used corresponds to an integrated luminosity of 35.9 fb(-1) recorded with the CMS detector at the LHC. Whereas previous searches for neutral scalar or pseudoscalar mediators considered dark matter production in association with a top quark pair only, this analysis also includes production modes with a single top quark. The results are derived from the combination of multiple selection categories that are defined to target either the single top quark or the top quark pair signature. No significant deviations with respect to the standard model predictions are observed. The results are interpreted in the context of a simplified model in which a scalar or pseudoscalar mediator particle couples to a top quark and subsequently decays into dark matter particles. Scalar and pseudoscalar mediator particles with masses below 290 and 300 GeV, respectively, are excluded at 95% confidence level, assuming a dark matter particle mass of 1 GeV and mediator couplings to fermions and dark matter particles equal to unity.Peer reviewe
Search for the pair production of light top squarks in the e(+/-)mu(-/+) final state in proton-proton collisions at root s=13 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WAT Wan
- Abdullin S
- Abdulsalam A
- Abercrombie D
- Abu Zeid S
- Ackert A
- Acosta D
- Acosta G
- Adam W
- Adams MR
- Adams T
- Adzic P
- Afanasiev S
- Agapitos A
- Agaras MN
- Aggleton R
- Agram J-L
- Ahmad A
- Ahmad M
- Ahmad M
- Ahmed I
- Ahuja S
- Akbiyik M
- Akchurin N
- Akgun B
- Al-Bataineh A
- Albajar C
- Albergo S
- Albert A
- Albrow M
- Alcaraz Maestre J
- Aleksandrov A
- Alexakhin V
- Alexander J
- Alhusseini M
- Ali MAB Md
- Alimena J
- Allen B
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- Alvarez Fernandez A
- Alvarez JD Ruiz
- Alverson G
- Alves FL
- Alves GA
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- Amendola C
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- Andreev Yu
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- Publication venue
- Publication date
- 01/01/2019
- Field of study
A search for the production of a pair of top squarks at the LHC is presented. This search targets a region of parameter space where the kinematics of top squark pair production and top quark pair production are very similar, because of the mass difference between the top squark and the neutralino being close to the top quark mass. The search is performed with 35.9 fb(-1) of proton-proton collisions at a centre-of-mass energy of root s = 13 TeV, collected by the CMS detector in 2016, using events containing one electron-muon pair with opposite charge. The search is based on a precise estimate of the top quark pair background, and the use of the M-T2 variable, which combines the transverse mass of each lepton and the missing transverse momentum. No excess of events is found over the standard model predictions. Exclusion limits are placed at 95% confidence level on the production of top squarks up to masses of 208 GeV for models with a mass difference between the top squark and the lightest neutralino close to that of the top quark.Peer reviewe
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