Monstrosity and Identity in the Comedias of Lope de Vega

Monstrosity and Identity in the Comedias of Lope de Vega is concerned with the relationship between monstrosity and identity formation in early modern Spain. The monster was a popular cultural phenomenon in sixteenth and seventeenth century Spain, appearing in a variety of scientific and literary genres. The monster was not just an extraordinary and unusual creature that elicited reactions of awe, wonder, and terror; it was also considered a sign from God that required careful interpretation to comprehend its meaning. The monster also embodies those characteristics that a society deems undesirable, and so by contrast, it shows what a society accepts and desires as part of its identity. In Lope de Vega's (1562-1635) comedias, the playwright depicts characters who challenged the social, political, and religious conventions of his time as monsters. This study of Lope's monsters intends to understand how and why Lope depicted these characters as monsters, and what they can tell us about the behaviors, beliefs, and traditions that Lope rejected as unacceptable or undesirable parts of the Spanish collective identity. It also seeks to understand, by contrast, what Lope thought Spanish identity was, or what he desired it to be. As the founding father of Spanish national theater and the playwright of the masses, this study of Lope's comedias and his monsters deepens our understanding of early modern Spanish collective self-fashioning.Doctor of Philosoph

Multiscale Genetic Structure of Yellowstone Cutthroat Trout in the Upper Snake River Basin.

Populations of Yellowstone cutthroat trout Oncorhynchus clarkii bouvierii have declined throughout their native range as a result of habitat fragmentation, overharvest, and introductions of nonnative trout that have hybridized with or displaced native populations. The degree to which these factors have impacted the current genetic population structure of Yellowstone cutthroat trout populations is of primary interest for their conservation. In this study, we examined the genetic diversity and genetic population structure of Yellowstone cutthroat trout in Idaho and Nevada with data from six polymorphic microsatellite loci. A total of 1,392 samples were analyzed from 45 sample locations throughout 11 major river drainages. We found that levels of genetic diversity and genetic differentiation varied extensively. The Salt River drainage, which is representative of the least impacted migration corridors in Idaho, had the highest levels of genetic diversity and low levels of genetic differentiation. High levels of genetic differentiation were observed at similar or smaller geographic scales in the Portneuf River, Raft River, and Teton River drainages, which are more altered by anthropogenic disturbances. Results suggested that Yellowstone cutthroat trout are naturally structured at the major river drainage level but that habitat fragmentation has altered this structuring. Connectivity should be restored via habitat restoration whenever possible to minimize losses in genetic diversity and to preserve historical processes of gene flow, life history variation, and metapopulation dynamics. However, alternative strategies for management and conservation should also be considered in areas where there is a strong likelihood of nonnative invasions or extensive habitat fragmentation that cannot be easily ameliorated

Evaluation of parameters for the propagation of three new hybrid citrus rootstocks of potential commercial use

Los portainjertos son clave en la producción de frutales leñosos, ya que influyen en la precocidad, tolerancia a plagas y enfermedades y en el vigor de las plantas. En el INTA EEA Bella Vista hay árboles adultos de híbridos que se encuentran en plena producción pero que aún no han sido evaluados como portainjertos potenciales para el sector citrícola del NEA. El objetivo del trabajo fue evaluar parámetros para la propagación de tres híbridos de cítricos con potencial uso comercial. Se evaluaron las características de árboles madre y frutos, poliembrionía, y comportamiento en almácigo. También luego de 0, 45, 90 y 180 días de almacenamiento se midió porcentaje de germinación y energía germinativa de 18 plantas de 3 híbridos procedentes de cruzamientos dirigidos: mandarino ‘Cleopatra’ [Citrus reshni Hort ex Tan.] × trifolio [Poncirus trifoliata (L.) Raf.] (Cl×Tf), ‘Citrange Troyer’ [C. sinensis (L.) Osbeck] × trifolio [P. trifoliata (L.) Raf.] × mandarino común [Citrus deliciosa Ten.] (T×C) y naranjo agrio Citrus auratium L. × mandarino ‘Cleopatra’ [Citrus reshni Hort ex Tan.] (Ag×Cl). Las plantas de menor tamaño a campo fueron las del híbrido de Ag×Cl. La combinación T×C tuvo buena cantidad de semillas y aseguró buen poder germinativo hasta 180 días almacenamiento. La alta poliembrionía de Cl×Tf aseguró la obtención de plantas nucelares en vivero.The rootstocks are an important section of the woody fruit scions, are key at the planification of the field because it influence on the precocity, pest and disease tolerance and on the vigor of the plants. At the INTA EEA Bella Vista there are adult trees of hybrids that are in full production but have not yet been evaluated as potential rootstocks for the NEA citrus sector. The objective of the work was to evaluate properties for the propagation of three hybrid citrus rootstocks with potential commercial use. Characteristics of mother trees and fruits, polyembryony, and seedling behavior were evaluated. Also, after 0, 45, 90 y 180 days of storage, germination percentage and energy were measured in eighteen plants from three hybrids: 1) ‘Cleopatra’ mandarin [Citrus reshni Hort ex Tan.] × trifolio [Poncirus trifoliata (L.) Raf.] (Cl×Tf), 2) ‘Citrange Troyer’ [C. sinensis (L.) Osbeck] × trifolio [P. trifoliata (L.) Raf.] × tangerina [Citrus deliciosa Ten.] (T×C) and 3) sour orange [Citrus auratium L. × ‘Cleopatra’ mandarin [Citrus reshni Hort ex Tan.] (Ag×Cl). The smallest plants in the field were that coming from Ag×Cl hybrid. The T×C combination has a good amount of seeds and its storage behavior ensures good germination until after 180 days of harvest. The Cl×Tf hybrid was the latest to germinate, but the high presence of polyembryony ensures the obtaining of nucelar plants in nursery.EEA Bella VistaFil: Cegelski, Leandro E. Universidad Nacional del Nordeste. Facultad de Ciencias Agrarias; Argentina.Fil: Beltrán, Víctor Manuel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Bella Vista; Argentina.Fil: Gaiad, José E. Universidad Nacional del Nordeste. Facultad de Ciencias Agrarias; Argentina.Fil: Alayón Luaces, Paula. Universidad Nacional del Nordeste. Facultad de Ciencias Agrarias; Argentina

Evaluación de parámetros para la propagación de tres nuevos portainjertos híbridos de cítricos con potencial uso comercial.

Los portainjertos son clave en la producción de frutales leñosos, ya que influyen en la precocidad, tolerancia a plagas y enfermedades y en el vigor de las plantas. En el INTA EEA Bella Vista hay árboles adultos de híbridos que se encuentran en plena producción pero que aún no han sido evaluados como portainjertos potenciales para el sector citrícola del NEA. El objetivo del trabajo fue evaluar parámetros para la propagación de tres híbridos de cítricos con potencial uso comercial. Se evaluaron las características de árboles madre y frutos, poliembrionía, y comportamiento en almácigo. También luego de 0, 45, 90 y 180 días de almacenamiento se midió porcentaje de germinación y energía germinativa de 18 plantas de 3 híbridos procedentes de cruzamientos dirigidos: mandarino ‘Cleopatra’ [Citrus reshni Hort ex Tan.] × trifolio [Poncirus trifoliata (L.) Raf.] (Cl×Tf), ‘Citrange Troyer’ [C. sinensis (L.) Osbeck] × trifolio [P. trifoliata (L.) Raf.] × mandarino común [Citrus deliciosa Ten.] (T×C) y naranjo agrio Citrus auratium L. × mandarino ‘Cleopatra’ [Citrus reshni Hort ex Tan.] (Ag×Cl). Las plantas de menor tamaño a campo fueron las del híbrido de Ag×Cl. La combinación T×C tuvo buena cantidad de semillas y aseguró buen poder germinativo hasta 180 días almacenamiento. La alta poliembrionía de Cl×Tf aseguró la obtención de plantas nucelares en vivero

Sistemas de control: La automatización como el motor del desarrollo

El siguiente trabajo es la recopilación de distintos materiales y experiencias en la industria regional sobre los Sistemas de Control y automatización de procesos de producción.El mismo fue compilado a través de los años por los  integrantes de la Cátedra de Sistemas de Control de la facultad de Ingeniería de la UNaM. La ingeniería del control es una ciencia que es usada en muchas disciplinas de la ingeniería, por ejemplo: ingeniería química, eléctrica, mecánica y es aplicada a un amplio rango de sistemas físicos, desde circuitos eléctricos hasta misiles guiados y el Ingeniero debe conocer las leyes que gobiernan a estos sistemas dinámicos y poder hacer uso de ellas.Es por esto que queremos hacerle llegar este material a los alumnos y  público en general, que esté interesado en el control de los sistemas dinámicos.Fil: Cegelski, Cristian Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Materiales de Misiones. Universidad Nacional de Misiones. Facultad de Ciencias Exactas Químicas y Naturales. Instituto de Materiales de Misiones; Argentina. Universidad Nacional de Misiones; ArgentinaFil: Katogui, Sergio Edgardo. Universidad Nacional de Misiones; ArgentinaFil: Stoisa, Hector Adelquis. Universidad Nacional de Misiones; ArgentinaFil: Corrado, Leandro Javier. Universidad Nacional de Misiones; ArgentinaFil: Nuñes, Manuel Fernando. Universidad Nacional de Misiones; Argentin

Targeting virulence not viability in the search for future antibacterials

New antibacterials need new approaches to overcome the problem of rapid antibiotic resistance. Here we review the development of potential new antibacterial drugs that do not kill bacteria or inhibit their growth, but combat disease instead by targeting bacterial virulence

Bacterial curli protein promotes the conversion of PAP248-286 into the amyloid SEVI: cross-seeding of dissimilar amyloid sequences

Fragments of prostatic acid phosphatase (PAP248-286) in human semen dramatically increase HIV infection efficiency by increasing virus adhesion to target cells. PAP248-286 only enhances HIV infection in the form of amyloid aggregates termed SEVI (Semen Enhancer of Viral Infection), however monomeric PAP248-286 aggregates very slowly in isolation. It has therefore been suggested that SEVI fiber formation in vivo may be promoted by exogenous factors. We show here that a bacterially-produced extracellular amyloid (curli or Csg) acts as a catalytic agent for SEVI formation from PAP248-286 at low concentrations in vitro, producing fibers that retain the ability to enhance HIV (Human Immunodeficiency Virus) infection. Kinetic analysis of the cross-seeding effect shows an unusual pattern. Cross-seeding PAP248-286 with curli only moderately affects the nucleation rate while significantly enhancing the growth of fibers from existing nuclei. This pattern is in contrast to most previous observations of cross-seeding, which show cross-seeding partially bypasses the nucleation step but has little effect on fiber elongation. Seeding other amyloidogenic proteins (IAPP (islet amyloid polypeptide) and Aβ1−40) with curli showed varied results. Curli cross-seeding decreased the lag-time of IAPP amyloid formation but strongly inhibited IAPP elongation. Curli cross-seeding exerted a complicated concentration dependent effect on Aβ1−40 fibrillogenesis kinetics. Combined, these results suggest that the interaction of amyloidogenic proteins with preformed fibers of a different type can take a variety of forms and is not limited to epitaxial nucleation between proteins of similar sequence. The ability of curli fibers to interact with proteins of dissimilar sequences suggests cross-seeding may be a more general phenomenon than previously supposed