1,514 research outputs found

    OER Plug And Play: De-mystifying OER for Faculty Using Brightspace 

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    This presentation will show faculty how to apply the OER Plug and Play strategy to their own campus OER outreach efforts. It will also demonstrate to faculty how to utilize OER and other no cost resources in a learning management system

    The Calculus War: The Ultimate Clash of Genius

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    Studies on the Teichoic Acids of the Pneumococcus

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    The investigations described in this dissertation are presented in two parts. Part I deals with the mode of segregation of the pneumococcal wall teichoic acid during cell growth and division. Teichoic acid was labeled with 3H-choline (a teichoic acid-specific constituent of pneumococci) or an analogue, and its distribution among progeny cells over several generations was followed by autoradiography. The results confirm the zonal growth model for Gram-positive coccal cells. In Part II, the pneumococcal Forssman antigen is identified as a membrane lipoteichoic acid. The following lines of evidence suggest that the teichoic acid chains of the molecule may be identical to those found in the cell wall: (1) they are both composed of the same chemical constituents, including choline; (2) they are both cleaved by periodate and by nitrous acid into choline-containing fragments of similar size; (3) previous investigators demonstrated serological cross-reactivity between the two (Goebel, W. and Adams, M.R., 1943, J. Exp. Med. 77:435-449). Membrane localization of the F-antigen is suggested by the following observations: (1) the F-antigen is accessible from the surface of whole pneumococci; (2) it is not solubilized by muralytic enzymes; (3) it contains lipophilic regions, and is associated with a particulate cell fraction by hydrophobic interactions. The possibility that the lipoteichoic acid may be a precursor to the wall teichoic acid is ruled out by pulse-chase studies

    Genetic variation of blood groups in inbred lines of Leghorns, derived from a common base population

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    Nine inbred lines of White Leghorn chickens were developed by continued brother X sister mating over 10 generations. Initial matings were made in 1968 by selecting at random full sibs within each of two outbred lines of White Leghorns, which themselves had been selected since 1960 from a single population for high and low egg weight, respectively. A third base population for inbred lines consisted of a cross between the two selected lines. Blood types for the A, B, E, C, D, H, I, K, L and P blood group systems were obtained for individuals belonging to nine surviving inbred lines in 1977. All systems showed differences between lines attesting to the diverse genetic origin of the initial 1960 population that was based on eight different breeding flocks. Among the nine inbred lines, three were found to segregate for a single system; two lines segregated for two systems; and three lines segregated for three systems. The ninth line (no 92) was found to be polymorphic for six of the blood group loci. The results agree with the assumption that none of the blood group systems by itself showed heterozygosity in excess of expectations for neutral genes. Intraline polymorphisms were in excess of neutral gene expectations only in one line in which substantial deviation from all other lines suggests that a recent pedigree error and not single-locus heterosis may be the source of its genetic variabilit
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