194 research outputs found
Pollinators visiting sesame (Sesamum indicum L.) seed crop with reference to foraging activity of some bee species
A study was conducted to
determine the insect pollinator orders
visiting sesame, fluctuation percent of
Hymenopterous fauna during flowering
period, foraging activity of the pollinating
insects belonging to Hymenoptera,
Coleoptera, Lepidoptera and Diptera orders
and foraging activity of Apis mellifera,
Anthidium sp. and Xylocopa sp. from July
15 to September 4, 2011 at four time
periods i.e., 9-11 am, 11-1 pm, 1-3 pm and
3-5 pm. Results revealed that insect
percentage of Hymenoptera order was high
followed by Lepidoptera, Diptera and
Coleoptera. The highest activity of
Hymenopterous fauna was in fourth week of
flowering period and decreased gradually in
the last weeks. Total number of pollinators
was highest at 9-11 am followed by that at
11-1 pm, 1-3 pm and 3-5 pm. Among the
bees, the number of Apis mellifera was the
maximum followed by Xylocopa sp. and
lastly Anthidium sp. at all time periods. It
was also evident that temperature, wind and
relative humidity also affect the percentage
of insects visiting sesame flowers
Effects of salicylic acid elicitor and potassium fertilizer as foliar spray on canola production in the reclaimed land in Ismailia governorate, Egypt
A field experiment was
conducted at the farm of Faculty of
Agriculture, Suez Canal University, Ismailia
Governorate, Egypt, during 2013/’14 and
2014/’15 seasons, to determine the effects
of salicylic acid elicitor (SA) and potassium
fertilizer (K) as foliar spray on canola
production in the reclaimed land. Canola
plants were sprayed with three rates of K
and SA separately and together. The
concentrations of SA with a surfactant
triton 0.1% and concentrations of K sprayed
after 30 days of sowing by one week
interval for three times using hydraulic
sprayer. Results indicated that K and SA
provided good nutrition and resistance for
pathogens, enhanced plant height (cm),
number of branches/ plant, fruiting zone
(cm), seed yield/ plant (g), seed yield/ fed
and oil percentage of canola cultivar
(Serw 4) in the reclaimed land. K and SA
separately or in combination at the rate of
(6.0 cm-1 + 300 mg-1 SA) provided the best
nutrition for enhancing resistance of plants
against biotic and a biotic factors,
consequently, enhancing vegetative growth
and yield production during seasons of
study 2013/’14 and 2014/’15
Ground Vehicle for Fire Fighting Purpose in Hazardous Environment
In this project, design, development and performance of a wirelessly controlled Fire Fighting Ground
Vehicle (FIGOV) is described. FIGOV is a wireless control mobile machine that is equipped with firefighting
equipment. It carries high density camera, sensors, communication equipment, firefighting equipment and
other loads in order to control fire and perform victim searching task. The machine is wirelessly controlled
via mobile computer. The nozzle of the machine can be directed at different angle and can be elevated
in order to control fire at different height. FIGOV can be used to reduce the risks faced by fire fighters in
performing their duties. This is due to the fact to the current fire fighting techniques require fire fighters
to intervene in hazardous conditions. Working at very high temperature, dusty, low humidity, dangerous
and others are among usual working conditions associated with fire fighting. Study conducted showed that
the machine can be successfully be used in real fire fighting process. Effective use of the machine also can
avoid direct contact of human especially fire fighter with radioactive or hazardous materials that may have
immediate or long-term effects on health as well as fatigue to human
Crosslinked thermoelectric hydro-ionogels:A new class of highly conductive thermoelectric materials
In this work, a new class of highly-conductive chemically cross-linked gel has been synthesized by the confinement of water and IL N, N, N triethyl octyl ammonium bromide ([N2228] Br) in polyethylene glycol dimethacrylate (PEGDMA) matrix, using in situ thermally initiated radical polymerization loaded with 1 wt% free radical initiator azobisisobutyronitrile (AIBN). This novel gel was named as hydro-ionogel (HIG). The thermoelectric properties of HIG such as ionic conductivity, Seebeck coefficient, and thermal conductivity were measured and owing to its high thermoelectric performance, we referred to this as crosslinked thermoelectric hydro-ionogel, henceforth will be denoted by X-TEHIG. For all the measurements, coin cells were fabricated using commercial LIR 2032 stainless steel battery casings with X-TEHIG sandwiched between the two graphene electrodes. The ionic conductivity of X-TEHIG was examined via AC impedance spectroscopy technique by using a Gamry apparatus. Remarkably, the ionic conductivity of X-TEHIG was higher than that of neat [N2228] Br. A linear increase in ionic conductivity of X-TEHIG as a function of temperature was recorded that showed a considerably higher value of 74 mScm−1 at 70 °C. The origin of this high conductivity is attributed to interactions between PEGDMA monomers and cations and anions of the IL and formation of hydrogen bonds between water and Br− anion, OH⋯Br−. X-TEHIG demonstrated a higher Seebeck coefficient of 1.38 mVK−1. The Fourier transform infrared (FTIR) spectroscopy results revealed the successful polymerization of X-TEHIG by the disappearance of CC peak of methacrylate group in the spectrum of PEGDMA. These results suggest that X-TEHIG may be a potential candidate for thermoelectric applications owing to their high values of ionic conductivity and Seebeck coefficient
High prevalence of PRPH2 in autosomal dominant retinitis pigmentosa in france and characterization of biochemical and clinical features.
PURPOSE: To assess the prevalence of PRPH2 in autosomal dominant retinitis pigmentosa (adRP), to report 6 novel mutations, to characterize the biochemical features of a recurrent novel mutation, and to study the clinical features of adRP patients.
DESIGN: Retrospective clinical and molecular genetic study.
METHODS: Clinical investigations included visual field testing, fundus examination, high-resolution spectral-domain optical coherence tomography (OCT), fundus autofluorescence imaging, and electroretinogram (ERG) recording. PRPH2 was screened by Sanger sequencing in a cohort of 310 French families with adRP. Peripherin-2 protein was produced in yeast and analyzed by Western blot.
RESULTS: We identified 15 mutations, including 6 novel and 9 previously reported changes in 32 families, accounting for a prevalence of 10.3% in this adRP population. We showed that a new recurrent p.Leu254Gln mutation leads to protein aggregation, suggesting abnormal folding. The clinical severity of the disease in examined patients was moderate with 78% of the eyes having 1-0.5 of visual acuity and 52% of the eyes retaining more than 50% of the visual field. Some patients characteristically showed vitelliform deposits or macular involvement. In some families, pericentral RP or macular dystrophy were found in family members while widespread RP was present in other members of the same families.
CONCLUSIONS: The mutations in PRPH2 account for 10.3% of adRP in the French population, which is higher than previously reported (0%-8%) This makes PRPH2 the second most frequent adRP gene after RHO in our series. PRPH2 mutations cause highly variable phenotypes and moderate forms of adRP, including mild cases, which could be underdiagnosed
Using verbal autopsy to measure causes of death: the comparative performance of existing methods
Background: Monitoring progress with disease and injury reduction in many populations will require widespread use of verbal autopsy (VA). Multiple methods have been developed for assigning cause of death from a VA but their application is restricted by uncertainty about their reliability.
Methods: We investigated the validity of five automated VA methods for assigning cause of death: InterVA-4, Random Forest (RF), Simplified Symptom Pattern (SSP), Tariff method (Tariff), and King-Lu (KL), in addition to physician review of VA forms (PCVA), based on 12,535 cases from diverse populations for which the true cause of death had been reliably established. For adults, children, neonates and stillbirths, performance was assessed separately for individuals using sensitivity, specificity, Kappa, and chance-corrected concordance (CCC) and for populations using cause specific mortality fraction (CSMF) accuracy, with and without additional diagnostic information from prior contact with health services. A total of 500 train-test splits were used to ensure that results are robust to variation in the underlying cause of death distribution.
Results: Three automated diagnostic methods, Tariff, SSP, and RF, but not InterVA-4, performed better than physician review in all age groups, study sites, and for the majority of causes of death studied. For adults, CSMF accuracy ranged from 0.764 to 0.770, compared with 0.680 for PCVA and 0.625 for InterVA; CCC varied from 49.2% to 54.1%, compared with 42.2% for PCVA, and 23.8% for InterVA. For children, CSMF accuracy was 0.783 for Tariff, 0.678 for PCVA, and 0.520 for InterVA; CCC was 52.5% for Tariff, 44.5% for PCVA, and 30.3% for InterVA. For neonates, CSMF accuracy was 0.817 for Tariff, 0.719 for PCVA, and 0.629 for InterVA; CCC varied from 47.3% to 50.3% for the three automated methods, 29.3% for PCVA, and 19.4% for InterVA. The method with the highest sensitivity for a specific cause varied by cause.
Conclusions: Physician review of verbal autopsy questionnaires is less accurate than automated methods in determining both individual and population causes of death. Overall, Tariff performs as well or better than other methods and should be widely applied in routine mortality surveillance systems with poor cause of death certification practices. © 2014 Murray et al.; licensee BioMed Central Ltd
Pharmacogenetics of Bleeding and Thromboembolic Events in Direct Oral Anticoagulant Users
Publisher Copyright: © 2021 The Authors. Clinical Pharmacology & Therapeutics published by Wiley Periodicals LLC on behalf of American Society for Clinical Pharmacology and TherapeuticsThis study aimed to analyze associations between genetic variants and the occurrence of clinical outcomes in dabigatran, apixaban, and rivaroxaban users. This was a retrospective real-world study linking genotype data of three Finnish biobanks with national register data on drug dispensations and healthcare encounters. We investigated several single-nucleotide variants (SNVs) in the ABCG2, ABCB1, CES1, and CYP3A5 genes potentially associated with bleeding or thromboembolic events in direct oral anticoagulant (DOAC) users based on earlier research. We used Cox regression models to compare the incidence of clinical outcomes between carriers and noncarriers of the SNVs or haplotypes. In total, 1,806 patients on apixaban, dabigatran, or rivaroxaban were studied. The ABCB1 c.3435C>T (p.Ile1145=, rs1045642) SNV (hazard ratio (HR) 0.42, 95% confidence interval (CI), 0.18-0.98, P = 0.044) and 1236T-2677T-3435T (rs1128503-rs2032582-rs1045642) haplotype (HR 0.44, 95% CI, 0.20-0.95, P = 0.036) were associated with a reduced risk for thromboembolic outcomes, and the 1236C-2677G-3435C (HR 2.55, 95% CI, 1.03-6.36, P = 0.044) and 1236T-2677G-3435C (HR 5.88, 95% CI, 2.35-14.72, P A (rs4148738) SNV associated with a lower risk for bleeding events (HR 0.37, 95% CI, 0.16-0.89, P = 0.025) in apixaban users. ABCB1 variants are potential factors affecting thromboembolic events in rivaroxaban users and bleeding events in apixaban users. Studies with larger numbers of patients are warranted for comprehensive assessment of the pharmacogenetic associations of DOACs and their relevance for clinical practice.Peer reviewe
Quantum gravity phenomenology at the dawn of the multi-messenger era—A review
The exploration of the universe has recently entered a new era thanks to the multi-messenger paradigm, characterized by a continuous increase in the quantity and quality of experimental data that is obtained by the detection of the various cosmic messengers (photons, neutrinos, cosmic rays and gravitational waves) from numerous origins. They give us information about their sources in the universe and the properties of the intergalactic medium. Moreover, multi-messenger astronomy opens up the possibility to search for phenomenological signatures of quantum gravity. On the one hand, the most energetic events allow us to test our physical theories at energy regimes which are not directly accessible in accelerators; on the other hand, tiny effects in the propagation of very high energy particles could be amplified by cosmological distances. After decades of merely theoretical investigations, the possibility of obtaining phenomenological indications of Planck-scale effects is a revolutionary step in the quest for a quantum theory of gravity, but it requires cooperation between different communities of physicists (both theoretical and experimental). This review, prepared within the COST Action CA18108 “Quantum gravity phenomenology in the multi-messenger approach”, is aimed at promoting this cooperation by giving a state-of-the art account of the interdisciplinary expertise that is needed in the effective search of quantum gravity footprints in the production, propagation and detection of cosmic messengers.publishedVersio
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
Galaxy And Mass Assembly (GAMA): data release 4 and the z < 0.1 total and z < 0.08 morphological galaxy stellar mass functions
Galaxie
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