219 research outputs found
Large Mesopelagic Fishes Biomass and Trophic Efficiency in the Open Ocean
- Author
- A Calbet
- A Calbet
- AD Smith
- AL Lara-Lopez
- CF Dormann
- CW Clark
- D Bianchi
- D Gascuel
- D Gascuel
- D Pauly
- DL Aksnes
- DL Aksnes
- DM Karl
- E San Martin
- EG Barham
- H Fock
- H Yasuma
- H Yasuma
- H Yasuma
- HB Moore
- J Aristegui
- JA Koslow
- JH Ryther
- JM Rose
- K Sawada
- KO Buesseler
- KO Buesseler
- L Tremblay-Boyer
- M Haraldsson
- MC Benfield
- MJ Behrenfeld
- NB Marshall
- NSR Agawin
- OR Godo
- P Davison
- PA del Giorgio
- PC Davison
- R Barr
- R Bernardes
- R Ihaka
- R Usbeck
- RJ Kloser
- RJ Kloser
- RJ Korneliussen
- RL O’Driscoll
- RW Wilson
- S Jennings
- S Jennings
- S Kaartvedt
- T Kiorboe
- T Torgersen
- TF Rangel
- V Christensen
- V Christensen
- V Lam
- W Smoker
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
With a current estimate of B1,000 million tons, mesopelagic fishes likely dominate the
world total fishes biomass. However, recent acoustic observations show that mesopelagic
fishes biomass could be significantly larger than the current estimate. Here we combine
modelling and a sensitivity analysis of the acoustic observations from the Malaspina 2010
Circumnavigation Expedition to show that the previous estimate needs to be revised to at
least one order of magnitude higher. We show that there is a close relationship between the
open ocean fishes biomass and primary production, and that the energy transfer efficiency
from phytoplankton to mesopelagic fishes in the open ocean is higher than what is typically
assumed. Our results indicate that the role of mesopelagic fishes in oceanic ecosystems and
global ocean biogeochemical cycles needs to be revised as they may be respiring B10% of
the primary production in deep water
Caspase-2 Mediated Apoptotic and Necrotic Murine Macrophage Cell Death Induced by Rough Brucella abortus
- Author
- A Celada
- A Ciaramella
- A Cloeckaert
- A Gross
- AI Martin-Martin
- AL Edinger
- B Mignotte
- B Raupach
- B Zhivotovsky
- BA Freeman
- BA Freeman
- BJ Bricker
- C Marianelli
- CA Hetz
- CM Fernandez-Prada
- CM Fernandez-Prada
- CM Troy
- D Gonzalez
- DS Zamboni
- E Barquero-Calvo
- E Galdiero
- F Porte
- Fang Chen
- G Kroemer
- G Krumschnabel
- G Majno
- G Pappas
- GD Fewell
- GG Schurig
- GG Schurig
- GG Schurig
- H Li
- IK Lee
- J Pei
- J Pei
- JC Reed
- JF Timoney
- JR McQuiston
- K Chang
- L Bergeron
- M Bras
- M Chen
- M Enoksson
- M Lara-Tejero
- M Tolomeo
- M van Engeland
- MG Rittig
- MG Stevens
- MK Dahmer
- MN Seleem
- MP Jimenez de Bagues
- MW Gray
- N Lapaque
- NA Thornberry
- NJ Yoo
- P Lassus
- PA Colussi
- PG Detilleux
- PJ Sansonetti
- R Vemulapalli
- RL Santos
- Robin Charles May
- Roop RM 2nd
- RV Talanian
- S Baumann
- S Faderl
- S Rodriguez-Enriquez
- S Sidi
- SD Dyall
- SL Fink
- T Bergsbaken
- V Jesenberger
- X Zhang
- Y Chen
- Y He
- Y He
- Y Zhang
- Yongqun He
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2009
- Field of study
Brucella species are Gram-negative, facultative intracellular bacteria that cause zoonotic brucellosis. Survival and replication inside macrophages is critical for establishment of chronic Brucella infection. Virulent smooth B. abortus strain 2308 inhibits programmed macrophage cell death and replicates inside macrophages. Cattle B. abortus vaccine strain RB51 is an attenuated rough, lipopolysaccharide O antigen-deficient mutant derived from smooth strain 2308. B. abortus rough mutant RA1 contains a single wboA gene mutation in strain 2308. Our studies demonstrated that live RB51 and RA1, but not strain 2308 or heat-killed Brucella, induced both apoptotic and necrotic cell death in murine RAW264.7 macrophages and bone marrow derived macrophages. The same phenomenon was also observed in primary mouse peritoneal macrophages from mice immunized intraperitoneally with vaccine strain RB51 using the same dose as regularly performed in protection studies. Programmed macrophage cell death induced by RB51 and RA1 was inhibited by a caspase-2 inhibitor (Z-VDVAD-FMK). Caspase-2 enzyme activation and cleavage were observed at the early infection stage in macrophages infected with RB51 and RA1 but not strain 2308. The inhibition of macrophage cell death promoted the survival of rough Brucella cells inside macrophages. The critical role of caspase-2 in mediating rough B. abortus induced macrophage cell death was confirmed using caspase-2 specific shRNA. The mitochondrial apoptosis pathway was activated in macrophages infected with rough B. abortus as demonstrated by increase in mitochondrial membrane permeability and the release of cytochrome c to cytoplasm in macrophages infected with rough Brucella. These results demonstrate that rough B. abortus strains RB51 and RA1 induce apoptotic and necrotic murine macrophage cell death that is mediated by caspase-2. The biological relevance of Brucella O antigen and caspase-2-mediated macrophage cell death in Brucella pathogenesis and protective Brucella immunity is discussed
The Hepatitis E Virus Polyproline Region Is Involved in Viral Adaptation
- Author
- A Mohan
- A Roy
- A Roy
- A Roy
- A Schlessinger
- AK Dunker
- B Meszaros
- CJ Tsai
- CM Gould
- D Eisenberg
- Darren P. Martin
- DL Swofford
- DT Jones
- EH Teshale
- EV Koonin
- EV Koonin
- F Legrand-Abravanel
- G Vriend
- H Liu
- HJ Dyson
- HJ Dyson
- HT Nguyen
- J Felsenstein
- James Lara
- JJ Ward
- L Willard
- M Fuxreiter
- M Takahashi
- MA Larkin
- MA Purdy
- MC Tettamanzi
- Michael A. Purdy
- MS Khuroo
- NA Baker
- P Puigbò
- P Shukla
- P Tompa
- PA Karplus
- R Chatterjee
- R Purcell
- RA Laskowski
- RC Edgar
- RD Finn
- RS Pudupakam
- RS Pudupakam
- S Ren
- S Vucetic
- S Wu
- SA Tsarev
- SL Ropp
- SLK Pond
- SU Emerson
- TA Hall
- V Vacic
- VA Arankalle
- VA Arankalle
- VN Uversky
- W Batts
- W Han
- W Kabsch
- W-P Tzeng
- WL DeLano
- XJ Meng
- Y Zhang
- Yury E. Khudyakov
- Z Dosztanyi
- Z Dosztányi
- Z Dosztányi
- Z Dosztányi
- Publication venue
- Public Library of Science
- Publication date
- 24/04/2012
- Field of study
Genomes of hepatitis E virus (HEV), rubivirus and cutthroat virus (CTV) contain a region of high proline density and low amino acid (aa) complexity, named the polyproline region (PPR). In HEV genotypes 1, 3 and 4, it is the only region within the non-structural open reading frame (ORF1) with positive selection (4–10 codons with dN/dS>1). This region has the highest density of sites with homoplasy values >0.5. Genotypes 3 and 4 show ∼3-fold increase in homoplastic density (HD) in the PPR compared to any other region in ORF1, genotype 1 does not exhibit significant HD (p<0.0001). PPR sequence divergence was found to be 2-fold greater for HEV genotypes 3 and 4 than for genotype 1. The data suggest the PPR plays an important role in host-range adaptation. Although the PPR appears to be hypervariable and homoplastic, it retains as much phylogenetic signal as any other similar sized region in the ORF1, indicating that convergent evolution operates within the major HEV phylogenetic lineages. Analyses of sequence-based secondary structure and the tertiary structure identify PPR as an intrinsically disordered region (IDR), implicating its role in regulation of replication. The identified propensity for the disorder-to-order state transitions indicates the PPR is involved in protein-protein interactions. Furthermore, the PPR of all four HEV genotypes contains seven putative linear binding motifs for ligands involved in the regulation of a wide number of cellular signaling processes. Structure-based analysis of possible molecular functions of these motifs showed the PPR is prone to bind a wide variety of ligands. Collectively, these data suggest a role for the PPR in HEV adaptation. Particularly as an IDR, the PPR likely contributes to fine tuning of viral replication through protein-protein interactions and should be considered as a target for development of novel anti-viral drugs
Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study.
- Author
- A Finckh
- Alejandro Balsa
- AM Gestel van
- AM Namboodiri
- American College of Rheumatology Committee to Reevaluate Improvement Criteria
- Ana Marquez
- Ann W Morgan
- Anne Barton
- Anthony G Wilson
- Antonio Fernández-Nebro
- Antonio Gonzalez
- Ariana Montes
- Arturo Rodríguez de la Serna
- Beatriz Joven
- Berta Magallares
- C Knox
- C Liu
- C Magdelaine-Beuzelin
- C Plasencia
- Cesar Magro
- CT Watson
- D Heath
- D Pascual-Salcedo
- D Plant
- D Tracey
- Darren Plant
- DJ Shealy
- Dora Pascual-Salcedo
- E Lander
- Enrique Raya
- Eva Perez-Pampin
- F Guillemin
- Federico Navarro-Sarabia
- Francisco J Blanco
- GJ Wolbink
- GM Bartelds
- GM Bartelds
- GM Bartelds
- J Cui
- J Fransen
- Javier Martin
- Javier Narváez
- JD Isaacs
- JD Isaacs
- JD Isaacs
- John Isaacs
- JP Pandey
- JP Pandey
- JP Pandey
- JP Pandey
- JR Maneiro
- JS Smolen
- Juan D Cañete
- Juan J Alegre-Sancho
- Juan J Gómez-Reino
- K Bendtzen
- K Chatzidionysiou
- Lara Valor
- M Umicevic Mirkov
- Manuel J Moreno-Ramos
- María del Carmen Ordóñez
- Miguel Angel Ferrer
- MJ Kidd
- MM Stickler
- MP Lefranc
- P Emery
- PA Schouwenburg van
- Patricia Carreira
- R Jefferis
- Rafael Caliz
- Rosa Garcia-Portales
- SB Krintel
- SM Tatarewicz
- T Rispens
- T Suzuki
- Theologia Sarafidou
- TR Radstake
- Virginia Moreira
- VJ Vieland
- Yiannis Vasilopoulos
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
INTRODUCTION: We have hypothesized that incompatibility between the G1m genotype of the patient and the G1m1 and G1m17 allotypes carried by infliximab (INX) and adalimumab (ADM) could decrease the efficacy of these anti-tumor necrosis factor (anti-TNF) antibodies in the treatment of rheumatoid arthritis (RA).
METHODS: The G1m genotypes were analyzed in three collections of patients with RA totaling 1037 subjects. The first, used for discovery, comprised 215 Spanish patients. The second and third were successively used for replication. They included 429 British and Greek patients and 393 Spanish and British patients, respectively. Two outcomes were considered: change in the Disease Activity Score in 28 joint (ΔDAS28) and the European League Against Rheumatism (EULAR) response criteria.
RESULTS: An association between less response to INX and incompatibility of the G1m1,17 allotype was found in the discovery collection at 6 months of treatment (P = 0.03). This association was confirmed in the replications (P = 0.02 and 0.08, respectively) leading to a global association (P = 0.001) that involved a mean difference in ΔDAS28 of 0.4 units between compatible and incompatible patients (2.3 ± 1.5 in compatible patients vs. 1.9 ± 1.5 in incompatible patients) and an increase in responders and decrease in non-responders according to the EULAR criteria (P = 0.03). A similar association was suggested for patients treated with ADM in the discovery collection, but it was not supported by replication.
CONCLUSIONS: Our results suggest that G1m1,17 allotypes are associated with response to INX and could aid improved therapeutic targeting in RA
Multi-messenger observations of a binary neutron star merger
- Author
- Aab A
- Aartsen MG
- Abbott BP
- Abbott R
- Abbott TD
- Abbott TMC
- Abdalla H
- Abe F
- Abeysekara AU
- Abramo LR
- Abramowski A
- Abreu P
- Acernese F
- Acero F
- Ackermann M
- Ackley K
- Ackley K
- Adams C
- Adams J
- Adams SM
- Adams T
- Addesso P
- Adhikari RX
- Adya VB
- Affeldt C
- Afrough M
- Agarwal B
- Agathos M
- Agatsuma K
- Aggarwal N
- Aglietta M
- Agliozzo C
- Agudo I
- Aguiar OD
- Aguilar JA
- Aharonian F
- Ahlers M
- Ahrens M
- Aiello L
- Ain A
- Ajith P
- Akras S
- Al Samarai I
- Albert A
- Albert A
- Albuquerque IFM
- Albury JM
- Alcaniz JS
- Alexander KD
- Alfaro R
- Alighieri S Di Serego
- Allam S
- Allekotte I
- Allen B
- Allen G
- Allison J
- Allison JR
- Allocca A
- Almela A
- Altin PA
- Altmann D
- Alvarez C
- Alvarez JD
- Alvarez M Dovale
- Alvarez-Muiz J
- Amati L
- Amato A
- An T
- Ananyeva A
- Anastasi GA
- Anchordoqui L
- Andeen K
- Anderson JP
- Anderson SB
- Anderson T
- Anderson WG
- Andrada B
- Andre M
- Andreoni I
- Andreoni I
- Andringa S
- Angelova SV
- Anghinolfi M
- Angner EO
- Angus CR
- Annis J
- Ansseau I
- Antier S
- Anton G
- Antonelli LA
- Antonelli LA
- Anupama GC
- Aoki K
- Aoki W
- Appert S
- Aptekar RL
- Arai K
- Arakawa M
- Aramo C
- Araya MC
- Arcavi I
- Arceo R
- Ardid M
- Areeda JS
- Aresu G
- Argan A
- Argelles C
- Arnaud N
- Array LWA Long Wavelength
- Array MWA Murchison Widefield
- Arrieta M
- Arsene N
- Arteaga-Velzquez JC
- Artola R
- Arun KG
- Asakura Y
- Asaoka Y
- Ascenzi S
- Ashall C
- Ashley MCB
- Ashton G
- Asorey H
- Assis P
- Ast M
- Aston SM
- Astone P
- Atallah DV
- ATLAS
- Atwood WB
- Aubert J-J
- Aubert P
- Aublin J
- Auffenberg J
- Aufmuth P
- Aulbert C
- AultONeal K
- Austin C
- Avgitas T
- Avila G
- Avila-Alvarez A
- Awad A Kuotb
- Axani S
- Baar S
- Babak S
- Bachetti M
- Backes M
- Bacon P
- Bader MKM
- Badescu AM
- Bae S
- Bagherpour H
- Bai X
- Bailes M
- Baker PT
- Balaceanu A
- Balanutsa PV
- Balasubramanian A
- Balbinot E
- Baldaccini F
- Baldini L
- Ballardin G
- Ballmer SW
- Bally J
- Balzer A
- Banagiri S
- Banerji M
- Bannister KW
- Barayoga JC
- Barbarino C
- Barbato F
- Barber AS
- Barbiellini G
- Barbiellini G
- Barclay SE
- Baret B
- Barish BC
- Barker D
- Barkett K
- Barnard M
- Barnes J
- Barone F
- Barr B
- Barrios-Marti J
- Barron JP
- Barsotti L
- Barsuglia M
- Barta D
- Barthelmy SD
- Bartlett J
- Bartos I
- Barway S
- Barway S
- Barwick SW
- Basa S
- Bassiri R
- Basti A
- Bastieri D
- Batch JC
- Bauer FE
- Bauer FE
- Baum V
- Bawaj M
- Bay R
- Bayley JC
- Bazzan M
- Bazzano A
- Bchele M
- Beardmore AP
- Beardsley A
- Beatty JJ
- Becerril A
- Becherini Y
- Bechtol K
- Becker KH
- Becsy B
- Beer C
- Bejger M
- Belahcene I
- Belhorma B
- Bell AS
- Bellazzini R
- Bellido JA
- Bellm E
- Belmont-Moreno E
- Benetti S
- Benkhali F Ait
- Benoit-Levy A
- BenZvi SY
- Berat C
- Berenji B
- Berge D
- Berger BK
- Berger E
- Bergmann G
- Berisso M Gomez
- Berley D
- Bernal A
- Bernardini E
- Bernardini MG
- Bernhard S
- Bernrhr K
- Bero JJ
- Beroiz M
- Berry CPL
- Bersanetti D
- Bertaina ME
- Bertin E
- Bertin V
- Bertolini A
- Berton M
- Bertou X
- Bessell MS
- Besson DZ
- Beswick R
- Betzwieser J
- Bhagwat S
- Bhalerao V
- Bhandare R
- Bhattacharya D
- Biagi S
- Biermann PL
- Bilenko IA
- Billingsley G
- Billman CR
- Binder G
- Bindig D
- Birch J
- Birney R
- Birnholtz O
- Biscans S
- Biscoveanu S
- Bisht A
- Bissaldi E
- Bissaldi E
- Biteau J
- Bitossi M
- Biwer C
- Bizouard MA
- Blackburn JK
- Blackburn L
- Blackman J
- Blackwell R
- Blaess SG
- Blagorodnova N
- Blair CD
- Blair DG
- Blair RM
- Blanchard P
- Blanco A
- Bland PA
- Blandford RD
- Blaufuss E
- Blazek J
- Bleve C
- Bloemen S
- Bloom ED
- Blot S
- Bock O
- Bode N
- Boer M
- Bogaert G
- Bohacova M
- Bohe A
- Bohm C
- Boisson C
- Bolmont J
- Bond IA
- Bondu F
- Bonifazi C
- Bonilla E
- Bonino R
- Bonnand R
- Bonnefoy S
- Bonoli S
- Booler T
- Boom BA
- Bordas P
- Bork R
- Bormuth R
- Borner M
- Borodai N
- Bos F
- Boschi V
- Bose D
- Bose S
- Boser S
- Bossie K
- Botner O
- Bottacini E
- Bottcher M
- Botti AM
- Botticella MT
- Bouffanais Y
- Bourbeau E
- Bourbeau J
- Bourret S
- Bouwhuis MC
- Bozzi A
- Bozzo E
- Brack J
- Bradaschia C
- Bradascio F
- Brady PR
- Branchesi M
- Brancus I
- Brandt S
- Brau JE
- Braun J
- Braun J
- Bravo O Martinez
- Brayeur L
- Breeveld AA
- Bregeon J
- Bregeon J
- Brenzke M
- Bretz H-P
- Bretz T
- Briant T
- Bridgeman A
- Briechle FL
- Briggs MS
- Brillet A
- Brinkmann M
- Brisbois C
- Brisson V
- Brnzas H
- Brocato E
- Brockill P
- Broderick JW
- Broida JE
- Bron S
- Brooks AF
- Brooks D
- Brostean-Kaiser J
- Brout D
- Brown DA
- Brown DD
- Brown IS
- Bruijn R
- Brun F
- Brun P
- Brunett S
- Brunner J
- Bruun SH
- Bryan M
- Buchanan CC
- Buchholz P
- Buckley DAH
- Buckley-Geer E
- Budnev NM
- Buehler R
- Bueno A
- Bufano F
- Buffa F
- Buikema A
- Buitink S
- Bulgarelli A
- Bulger J
- Bulik T
- Bulik T
- Bulla M
- Bulten HJ
- Buonanno A
- Burgay M
- Burgess JM
- Burgman A
- Burhonov O
- Burke DL
- Burns E
- Burrows DN
- Buscemi M
- Buskulic D
- Buson S
- Bustillo J Caldern
- Busto J
- Butler NR
- Butler RE
- Buttu M
- Buy C
- Byer RL
- Caballero-Garcia MD
- Caballero-Mora KS
- Caballero-Mora KS
- Cabero M
- Cabral J
- Caccianiga L
- Cadonati L
- Cagnoli G
- Cahillane C
- Callister TA
- Calloni E
- CALTECH GROWTH JAGWAR
- Cameron RA
- Camilo F
- Camp JB
- Campana S
- Camuccio R
- Cancio A
- Canepa M
- Canfora F
- Canizares P
- Cannella C
- Cannizzaro G
- Cannon KC
- Cano Z
- Cao H
- Cao J
- Cao XL
- Capaccioli M
- Capano CD
- Capasso M
- Capistrn T
- Capocasa E
- Capone A
- Capozzi D
- Cappellaro E
- Caputo R
- Caramete L
- Caraveo P
- Caraveo PA
- Carbognani F
- Carboni G
- Cardenas B Vargas
- Cardillo M
- Caria T
- Caride S
- Carlin JL
- Carney MF
- Caroff S
- Carosi A
- Carr J
- Carramiana A
- Carretti E
- Cartier R
- Caruso R
- Carver T
- Casadio C
- Casado A Lopez
- Casanova S
- Casanova S
- Casasola V
- Casella P
- Casentini C
- Casey J
- Casier M
- Castander FJ
- Castangia P
- Castellina A
- Castellon A
- Castellon JL Nilo
- Castillo J Alvarez
- Castillo M
- Castro JM Gonzalez
- Castro ML Diaz
- Castro-Tirado AJ
- Casu S
- Catalani F
- Cataldi G
- Cattaneo PW
- Caudill S
- Cavagli M
- Cavalier F
- Cavalieri R
- Cavazzuti E
- Cazon L
- Cella G
- Celli S
- Cenko SB
- Cepeda CB
- Cerd-Durn P
- Ceron JM Castro
- Cerretani G
- Cerruti M
- Cerutti AC Cobos
- Cesarini E
- Chakraborty N
- Chamberlin SJ
- Chambers KC
- Chan M
- Chandra P
- Chang S-W
- Chang Z
- Chao S
- Charlton P
- Chase E
- Chassande-Mottin E
- Chatterjee D
- Chatterjee D
- Chatziioannou K
- Chaves RCG
- Chavez AG
- Chavushyan V
- Cheeseboro BD
- Chekhtman A
- Chen A
- Chen G
- Chen HY
- Chen L
- Chen T-W
- Chen TX
- Chen X
- Chen Y
- Chen Y
- Chen YB
- Chen YP
- Chenevez J
- Cheng H-P
- Cherry ML
- Cheung CC
- Cheung E
- Chevalier J
- Chia H
- Chiang J
- Chiarusi T
- Chincarini A
- Chinellato JA
- Chirkin D
- Chiummo A
- Chmiel T
- Cho HS
- Cho M
- Choi C
- Choi J-S
- Chornock R
- Chow JH
- Christensen N
- Christov A
- Chu Q
- Chua AJK
- Chua S
- Chudoba J
- Chung AKW
- Chung S
- Ciani G
- Cikota A
- Ciolfi R
- Ciprini S
- Circella M
- Cirelli CE
- Cirone A
- Clara F
- Clark JA
- Clark K
- Clark P
- Clarke TE
- Classen L
- Clay RW
- Clearwater P
- Cleva F
- Cleveland WH
- Cline T
- Cobb BE
- Cocchieri C
- Coccia E
- Coelho JAB
- Coelho P
- Coenders S
- Cohadon P-F
- Cohen D
- Cohen-Tanugi J
- Colafrancesco S
- Colafrancesco S
- Colalillo R
- Colazo C
- Coleiro A
- Coleman A
- Colla A
- Collaboration ALMA
- Collaboration ANTARES
- Collaboration BOOTES
- Collaboration CALET
- Collaboration DLT40
- Collaboration HAWC
- Collaboration HESS
- Collaboration IceCube
- Collaboration IKI-GW Follow-up
- Collaboration Insight-Hxmt
- Collaboration IPN
- Collaboration KU
- Collaboration LOFAR
- Collaboration MASTER
- Collaboration Pi Sky
- Collaboration Pierre Auger
- Collaboration Swift
- Collaboration VINROUGE
- Collette CG
- Collica L
- Collin GH
- Colmenero E Romero
- Coluccia MR
- Cominsky LR
- Cominsky LR
- Conceicao R
- Concu R
- Condon B
- Coniglione R
- Connaughton V
- Conrad J
- Conrad JM
- Consolati G
- Consortium TZAC
- Constancio M
- Conti L
- Contreras F
- Cook DO
- Cook ER
- Cooke J
- Cooper MJ
- Cooper SJ
- Copperwheat C
- Corban P
- Corbitt TR
- Cordero-Carrion I
- Corley KR
- Cornish N
- Corongiu A
- Corral-Santana JM
- Corsi A
- Cortese S
- Costa CA
- Costa CF Da Silva
- Costa E
- Costa-Duarte MV
- Costantin D
- Costantini H
- Cotti U
- Cotzomi J
- Coughlin M
- Coughlin MW
- Coughlin SB
- Coulon J-P
- Coulter DA
- Countryman ST
- Courvoisier TJ-L
- Coutu S
- Couvares P
- Covas PB
- Covault CE
- Covino S
- Cowan EE
- Coward DM
- Coward DM
- Cowart MJ
- Cowen DF
- Cowperthwaite P
- Coyle P
- Coyne DC
- Coyne R
- Crawford S
- Creighton JDE
- Creighton TD
- Creusot A
- Cripe J
- Crisp H
- Crocce M
- Cronin J
- Cross R
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- Lundgren AP
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- Mazumder N
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- Michael T
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- Micheletti MI
- Michelson PF
- Middendorf L
- Middleton H
- Migliozzi P
- Migoni Carlo
- Mihara T
- Mikhailov EE
- Milano L
- Milia Sabrina
- Miller AA
- Miller CJ
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- Milovich-Goff MC
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- Minaev P Yu
- Minazzoli O
- Minenkov Y
- Minervini G
- Ming J
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- Mitselmakher G
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- Miyasaka H
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- Mockler D
- Moderski R
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- Moggi A
- Mogushi K
- Mohamed M
- Mohan M
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- Mohr JJ
- Mohrmann L
- Moldon J
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- Mollerach S
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- Montani M
- Montaruli T
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- Moreno E
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- Morihana K
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- Mours B
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- Ramos-Buades A
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- RATIR RIMAS
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- Read J
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- Regimbau T
- Rei L
- Reichart DE
- Reid S
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- Reimer A
- Reimer A
- Reimer O
- Reimer O
- Reitze DH
- Relethford B
- Relich M
- Ren W
- Ren Z
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- Renzi V
- Reposeur T
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- Resmi L
- Rest A
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- Richman M
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- Ridden-Harper R
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- Rios-Lopez E
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- Zadrozny A
- Zaharijas G
- Zaltzman M
- Zanin R
- Zanolin M
- Zaremba M
- Zarnecki AF
- Zas E
- Zavrtanik D
- Zavrtanik M
- Zdziarski AA
- Zech A
- Zefi F
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- Zenko T
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- Zepeda A
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- Zhang YF
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- Zhao C
- Zhao HS
- Zhao JL
- Zhao W
- Zhao XF
- Zheng SJ
- Zhou H
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- Zhou M
- Zhou Z
- Zhu SJ
- Zhu XJ
- Zhu Y
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- Ziegler A
- Zimmerman AB
- Zimmermann B
- Zimnukhov DS
- Ziolkowski M
- Zoll M
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- Zorn J
- Zornoza JD
- Zou CL
- Zuccarello F
- Zucker ME
- Zuniga J
- Zweizig J
- Zywucka N
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
- Author
- Abad Pedro
- Abbara Suhny
- Abbasi Taimur
- Abbott Brian
- Abdel Aziz Islam Shawky
- Abdulla Jawdat
- Abikhzer Gad
- Abohashem Shady
- Abougabal Mahasen
- Abramson Sandra
- Abrihan Paz
- Acuña Arturo Romero
- Affandi Erwin
- Afzal Muhammad Shehzad
- Agolti Mariela
- Agranovich Svetlana
- Aguadé-Bruix Santiago
- Aguero Roberto Nicolas
- Ahmed Hassan Mohamed Ismail
- Ahmed Taghreed
- Akhter Afroza
- Al Dhuhli Humoud
- Al Kindi Faiza
- Al-Abboud Tarek
- Al-Bulushi Naeema
- Al-Mallah Mouaz
- Alak Maria del Carmen
- Alam Edison
- Alaoui Nadia Ismaili
- Alasnag Mirvat
- Albadr Amjed
- Albalooshi Batool
- Albano Domenico
- Alberguina Lucia Graciela
- Albernaz Siqueira Maria Helena
- Alexanderson-Rosas Erick
- Alfaro Ana
- Ali Mohamed Mandour
- Alkadhi Hatem
- Alkandari Faridah
- Allam Adel
- Allarakha Mohammad Aaftaab
- Almeida Augusto
- Almousalli Omar
- Alongi Pierpaolo
- Alonso Omar
- Alves Togni Paulo Henrique
- Alves Wilson Furlan
- Ananthasubramaniam Karthikeyan
- Anderson Jill
- Andrade Jose Henrique
- Andrade Luciana
- Angelidis George
- Anselmi Carlos
- Ansheles Alexey
- Araújo Roberta
- Archontaki Aikaterini
- Arnone Gaspare
- Arnous Samer
- Arnson Yoav
- Arroñada Guillermo
- Arturo Harold
- Asano Hiroshi
- Ascani Sebastian Perez
- Asfour Ahmed
- Askew Jeffrey
- Assadi Majid
- Astesiano Alfredo
- Astesiano Andrea
- Attanasio Lea
- Atyani Said
- Ayala Sandra
- Ayetey Harold
- Ayodele Tolulope
- Azevedo Guilherme
- Bagatin Elisa
- Bailly Matthieu
- Baldari Sergio
- Balmer-Swain Mallory
- Bang Ji-In
- Banthia Nilesh
- Bar-Shalom Rachel
- Barette Rene
- Baric Ana
- Barneveld Peter
- Barragan Adriana Puente
- Barragan Erika
- Barroso Asela
- Basavaraj Ashok Gangasandra
- Batinic Tonci
- Batista Juan Felipe
- Batyrkhanov Daultai
- Bauckneht Matteo
- Baugh Dainia
- Bayer Richard R.
- Bedi Punit
- Bejai Shereen
- Ben-Rais Nozha
- Benedek Imre
- Benedek Theodora
- Benitez Luis
- Benlabgaa Rabie
- Bennie George
- Benteo Pablo
- Beretta Mario
- Berman Daniel S.
- Bernheim Adam
- Bertelli Paolo
- Bester Ria
- Bettencourt Nuno
- Better Nathan
- Better Nathan
- Beuzeville Scott
- Bezerra Sabbrina
- Bhagat Jinendra Kumar
- Bhargava Rishi
- Bhat Vivek
- Bhatia Mona
- Bhatti Sabha
- Biancardi Rodrigo
- Bianco Francesco
- Bieging Erik
- Biggans Thomas
- Bittencourt Marcio Sommer
- Blanco Isabel
- Blanco Juan
- Blankstein Ron
- Blankstein Ron
- Bloom Stephen
- Blue Sean
- Bluemke David
- Bluemke David A.
- Boktor Raef
- Bom Henry
- Bonelli Juan Manuel
- Bonfiglioli Rachele
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- Branch Kelley
- Brandão Simone
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- Brothers Jessica
- Bruno Andrea
- Bruno Isabella
- Bråten Anders Tjellaug
- Budoff Matthew
- Buechel Ronny Ralf
- Buga Klara
- Bularga Anda
- Bull Russell
- Bullock-Palmer Renée
- Burandt Angela
- Burg Samuel
- Burger Peter
- Burgul Rajesh
- Burke Floyd W.
- Bush Kelvin
- Busnardo Elena
- Bustos Jose Javier
- Butler Patrick
- Byrne Angela
- Bøttcher Morten
- Cabada Manuel
- Cabeda Estevan Vieira
- Cabrejas Raul
- Cabrera Antonio
- Cachero Jorge
- Cadena Alberto
- Caicedo Carlos
- Calcott Jennifer
- Califaretti Elena
- Camarero Alicia
- Camoni Luca
- Campisi Roxana
- Canal Maria Pedrera
- Candela Candace
- Canderoli Alejandro
- Canessa Jose
- Cantinho Guilhermina
- Cao Dianbo
- Capasso Elizabeth
- Carames Silvia
- Carnevale Aldo
- Carpenter John-Paul
- Carr Loretta
- Carrascosa Patrícia
- Carreira Lara
- Carvajal-Juarez Isabel
- Casoni Roberta
- Castro Bruno
- Castro Gabriel
- Castro Ricardo
- Casáns-Tormo Irene
- Cavalcante Joao
- Cavallo Armando Ugo
- Cavenaghi Giorgio
- Cendoya Oscar
- Cerci Rodrigo
- Cerci Rodrigo J.
- Ceriani Luca
- Chambers Duane
- Chan Virgil
- Chang Donald
- Chang Tien
- Chao Charles
- Chatterjee Saurav
- Chatziioannou Sofia
- Chatzizisis Yiannis
- Cheezum Michael
- Chen Jennifer
- Chen Marcus
- Chen Tiffany
- Cheung Stephen
- Chierichetti Franca
- Chimura Chimura Misato
- Chiocchi Marcello
- Cho Sang-Geon
- Choi Andrew
- Choi Andrew
- Choi Andrew D.
- Chong Woon
- Choudhury Partha
- Chow Benjamin
- Chowdekar Vijay Sai
- Christensen Mette
- Cittanti Corrado
- Clarcq James
- Cognigni Luciano Martin
- Cohen Yosef
- Cohen Yosef A.
- Coie Tchoyoson Lim
- Coles Duncan
- Collaud Carlos
- Collaud Carlos
- Colletta Mauro
- Concha Carmen
- Conti Umberto
- Cordero Ayreen
- Cortes Claudia
- Cortés Filiberto
- Cortés Violeta
- Cossu Alberto
- Courtis Javier
- Cragnolino Daniel
- Crim Matthew
- Cruz Eric
- Cuadra Teresa
- Cuellar-Calabria Hug
- Cunali Fernando
- Cuocolo Alberto
- Cury Roberto
- Cusack David
- Cuzzocrea Marco
- Dabreo Dominique
- Dai Xu
- Daicz Mariana
- Danciu Sorin
- Dantas Roberto
- Dariy Olga
- Datseris Ioannis
- Dautov Tairkhan
- de Amorim Fernandes Fernando
- De Boeck Bart
- De Carvalho Filipe Penna
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- De La Vega Alejandro
- De Lorenzo Andrea
- De Macedo Filho Robson
- De Maria Silvia Teresa
- De Rimini Maria Luisa
- De Souza Thiago Ferreira
- De Vincentis Giuseppe
- Decter Bruce
- Del Giudice Eleonora
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- Deshpande Aparna
- Dettori Fernando
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- Deviggiano Alejandro
- Dhruva Nimish
- Diaz Javier Lopez
- Djuraev Omoa
- Dobson Mark
- Doherty Neil
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- Dunbar Anjori
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- Duvall William
- Dwivedi Girish
- Edmond John
- Edwards Rachael
- Efros-Monsen Elen
- Einstein Andrew J.
- Einstein Andrew J.
- Elison Barry
- Ellis Chris
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- Embon Mario
- Engela Jean
- Engelbrecht Gerrit
- Engelmann Vaclav
- Enriquez Ruben Emilio
- Ensinas Jorge
- Erba Paola Anna
- Erthal Fernanda
- Escobar Manuel Valencia
- Escorza Velez Giovanni Alejandro
- Espeche Maria del Huerto Velazquez
- Esquitin Kerry
- Evangelista Laura
- Evbuomwan Osayande
- Faccio Fernando
- Facello Adolfo
- Fairbairn Timothy
- Faletti Riccardo
- Faragasso Evelina
- Faraggi Marc
- Farah Husam
- Farrugia Alexia
- Farsad Mohsen
- Fatima Shazia
- Fentanes Emilio
- Ferencik Maros
- Ferencik Maros
- Fernandes Fabio
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- Gama-Moreno Manlio
- Gamboa Isabel Berrocal
- Gannon Michael
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- Gatti Marco
- Gaudiano Angela
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- Gheysens Olivier
- Ghimire Ram Kumar
- Ghini Bruno
- Ghoshhajra Brian
- Gimelli Alessia
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- Giubbini Raffaele
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- Glaudemans Andor
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- Goda Artan
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- Goldberg Alan
- Goldner Brian
- Gomez Marie Rhiamar
- Gomez Sharon
- Goncalves Luiz
- Gong Lianggeng
- Gongxeka Harlem
- Gonza Natalia
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- Goodwin Bruce
- Gopalan Deepa
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- Gottlieb Ilan
- Gracia-López Sandra
- Greenough Robert
- Grossman Gabriel Blacher
- Gräni Christoph
- Gulyaev Vsevolod Milyevich
- Gummow Alistair
- Gunawan Gani
- Gutierrez Villamil Claudia T.
- Gutierrez Goleat
- Gutierrez Lucas
- Gutierrez Yamile Marcos
- Gutierrez Yamile Marcos
- Guzzo Miguel Angel
- Guzzo Miguel Angel
- Gómez Lauchy Juan Manuel
- Habets Jesse
- Habouzit Vincent
- Hadlich Marcelo
- Hafez Mohammed Nassoh
- Hage Fadi
- Haidar Mohamad
- Haider Agha
- Haider Sofia
- Hamilton Mark
- Hamilton-Craig Christian
- Hamirani Yasmin
- Han Dan
- Hapkido Habusari
- Harbinson Mark
- Hartley Thomas
- Hasbak Philip
- Hasbani Victor
- Hashimoto Jun
- Hassan Alia
- Hassan Mona
- Hassen Karen
- Hatfield Mallory
- Hawkins Carolyn
- Hawthorne Katie
- Heath Nicholas
- Hendel Robert
- Hernandez Phillip
- Hernández Gertrudis Sabatel
- Herrera Yariela
- Hess Søren
- Hidalgo Pablo
- Hidayat Basuki
- Hildre Dimmen Jenni-Mari
- Hill Gregory
- Hinterleitner Gerd
- Hirschfeld Cole B.
- Hirschfeld Cole B.
- Holdgaard Paw
- Homans Filip
- Hong Chae Moon
- Horgan Stephen
- Hou Yang
- Houshmand Golnaz
- Hsieh Victar
- Hua Shaw
- Huda Aulia
- Hudson Benjamin
- Huerin Melina
- Huffman Jeff
- Hurwitz Lynne
- Hyafil Fabien
- Ialuna Salvatore
- Ibrahim Ahmed
- Ichikawa Yasutaka
- Iguchi Nobuo
- Iii George Kinzfogl
- Ilic Srdja
- Imai Masamichi
- Inaki Anri
- Irodi Aparna
- Ishimura Hayato
- Iskandrian Ami
- Isobe Satoshi
- Issoufou Djibrillou Moussa
- Itskovich Irina
- Jaimes Claudia
- Jain Shashank
- Janardhanan Rajesh
- Jang Su Jin
- Jason See Jia Hao
- Jawa Zabah
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- Jimenez-Heffernan Amelia
- Jiménez-Santos Moisés
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- Johnson Chris
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- Kaffas Sameh
- Kalinin Artem
- Kalnina Marika
- Kalra Dinesh
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- Kameoka Vinícius
- Kaminek Milan
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- Kang Won Jun
- Kapitan Miguel
- Kaplan Mitchell
- Karalkin Anatoly
- Karim Noor Khairiah A.
- Kato Takao
- Kaviratne Summanther
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- Kay Fernando
- Kay Michael
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- Kokkonen Velipekka
- Kokov Alexander
- Komiagiene Renata
- Kontos Michael
- Koopmans Klaas Pieter
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- Narula Jagat
- Narula Jagat
- Naseer Hamid
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- Ng Ming Yen
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- Nieves A López De Munaín Maria
- Nijjar Prabhjot
- Nogueira Ramos Rodrigo Rizzo
- Noguera Eduardo
- Nolasco Roberto
- Nomura Cesar
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- Norikane Takashi
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- Novoa Carlos
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- Nørgaard Bjarne Linde
- O'Brien Julie
- O'Rourke Edward
- O'Sullivan Patricia
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- Oikonomou Anastasia
- Okarvi Subhani
- Okayama Satoshi
- Okizaki Atsutaka
- Oliveira Joao Bruno
- Ombati Kevin
- Onimode Yetunde
- Ornelas Mario
- Ortellado José
- Ortga Ramirez Jose Alberto
- Osman Medhat
- Otomi Yoichi
- Otsuka Hideki
- Ozair Ahmad
- Paar Maja Hrabak
- Pabon Luz
- Pacella Sara
- Padma Savenadia
- Paez Diana
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- Pandos George
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- Pathmaraj Kunthi
- Patil Pravin
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- Pawhay Christian Michael
- Pedras Felipe Villela
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- Persic Viktor
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- Pianta Diego Bromfman
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- Quartuccio Natale
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- Rabbat Mark
- Radzinschi Alejandro
- Raggi Paolo
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- Raimondi Gustavo
- Rajbanshi Bijoy
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- Riaz Musab
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- Uretsky Seth
- Uson Kristine Joy
- Ussov Wladimir Yurievich
- Uusitalo Valtteri
- Uy Mila
- Vajauskas Donatas
- Vakhromeeva Margarita
- Valiullina Nailya
- Vallejo Enrique
- Valles Mario
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- Vallée Jean-Paul
- Valsamaki Pipitsa
- Vamadevan Shankar
- Van Asperen Erik-Jan
- Van De Heyning Caroline M.
- Van Gaal William
- Van Pelt Niels
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- Vasquez Andres
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- Vergel Damiana
- Verjans Johan
- Verma Atul
- Verma Vikas
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- Veríssimo Otávia
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- Villines Todd C.
- Vitola Joao V.
- Vitola Joao V.
- Vondrak Andrej
- Voutnis Demetrius
- Vuuren Magritha Jv
- Várady Edit
- Vázquez Manuel Castillo
- Wagenaar Nils
- Wakabayashi Yasushi
- Waller Alfonso
- Waltrick Roberto
- Wang Ellen
- Wang Jian
- Wang Ximing
- Wang Yifan
- Wang Yining
- Wang Zhao-Qian
- Ward Parker
- Wayne Victor
- Weihmuller Juan Sebastian
- Weir-Mccall Jonathan
- Weiss Konrad
- Weissman Gaby
- Wesbey George
- White James
- White Kelly
- Williams Michelle C.
- Williams Michelle C.
- Wilson Peter
- Winchester David
- Winchester David
- Wolcan Juan
- Wolinsky David
- Won Kyoung Sook
- Wong David
- Wong Kirby
- Wu Jiang
- Wu Zhifang
- Xia Liming
- Xiao Jiangxi
- Xu Lei
- Xu Zhuoran
- Yamada Shinichiro
- Yamazaki Shinya
- Yang Youyou
- Yew Min Sen
- Yin Wu
- Yoneyama Tatsuya
- Yost Sandra
- Young Calum
- Younger John
- Younis Muhammad Numair
- Yu Jianqun
- Yuan Li
- Zaid Eed Abu
- Zakavi Seyed Rasoul
- Zapparoli Marcello
- Zavadovsky Konstantin
- Zeffiro Susana
- Zeidán Nahla
- Zerahn Bo
- Zgaljardic Michael
- Zhang Longjiang
- Zhang Tong
- Zhang Xiaoli
- Zhang Yong-Gao
- Zhu Li
- Zhuravlev Kirill
- Zoboli Stefania
- Zukotynski Katherine
- Zuluaga Alejandro
- Øvrehus Kristian Altern
- Štalc Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
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- Yu WH
- Yu Z
- Yu Z
- Yuan J
- Yuan L-Q
- Yuan S
- Yuan S-SF
- Yuan Y
- Yuan Z
- Yue J
- Yue Z
- Yun J
- Yung RL
- Zacks DN
- Zaffagnini G
- Zambelli VO
- Zanella I
- Zang QS
- Zanivan S
- Zappavigna S
- Zaragoza P
- Zarbalis KS
- Zarebkohan A
- Zarrouk A
- Zeitlin SO
- Zeng J
- Zeng J-D
- Zhan L
- Zhang B
- Zhang DD
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H-L
- Zhang J
- Zhang J
- Zhang J-P
- Zhang KYB
- Zhang L
- Zhang L
- Zhang L
- Zhang L
- Zhang LW
- Zhang M
- Zhang P
- Zhang S
- Zhang W
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X-W
- Zhang XD
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y-D
- Zhang Y-Y
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhao H
- Zhao L
- Zhao S
- Zhao T
- Zhao X-F
- Zhao Y
- Zhao Y
- Zhao Y
- Zhao Y
- Zheng G
- Zheng K
- Zheng L
- Zheng S
- Zheng X-L
- Zheng Y
- Zheng Z-G
- Zhivotovsky B
- Zhong Q
- Zhou A
- Zhou B
- Zhou C
- Zhou G
- Zhou H
- Zhou H
- Zhou H
- Zhou J
- Zhou J
- Zhou J
- Zhou J
- Zhou K
- Zhou R
- Zhou X-J
- Zhou Y
- Zhou Y
- Zhou Y
- Zhou Z
- Zhou Z-Y
- Zhu B
- Zhu C
- Zhu G-Q
- Zhu H
- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Álvarez ÉMC
- Ávalos Y
- Önal G
- Üstün S
- Čolić M
- Đokić J
- Žerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Alternative splicing: the pledge, the turn, and the prestige
- Author
- A Aartsma-Rus
- A Berger
- A DeMicco
- A Goren
- A Haraga
- A Ivanov
- A Kalsotra
- A Krämer
- A Malamitsi-Puchner
- A Mankodi
- A Pawellek
- A Peri
- A Sureau
- A Sveen
- A Zaghlool
- A. C. Leote
- AA Melton
- AD Norris
- AG Matera
- AGL Douglas
- AJ Linares
- AJ Ward
- AJ Westermann
- AJ Westermann
- AL Shaffer
- AM Muise
- AN Brooks
- AN Kuhn
- AR Grosso
- AR Grosso
- AR Krainer
- AR Krainer
- AV Chee
- B Chabot
- B Hu
- B Ng
- B Raj
- B Raj
- B Raj
- B Ruskin
- B Ruskin
- B Treutlein
- BD Berkovits
- BJ Albert
- BJ Blencowe
- BJG Baaten
- BK Dredge
- C Francavilla
- C Gao
- C Ghigna
- C Holland
- C Karakaya
- C Kress
- C Liu
- C Vernet
- C Wei
- C Zhu
- CA Opitz
- CA Turner Jr
- CH George
- CJ David
- CJ David
- CK Vuong
- CM Koh
- CR Rothrock
- CV Clower
- D Ahmadi Rastegar
- D Dominguez
- D Hanahan
- D Kumar
- D Lipscombe
- D Memon
- D Sakamuro
- DD Licatalosi
- DD Licatalosi
- DG Nowak
- DJ Elliott
- DO Bates
- DP Hughes
- DW Seol
- DW Walke
- E Brody
- E Lara-Pezzi
- E Lara-Pezzi
- E Sebestyén
- E Sebestyén
- EJ Love
- EL Heinzen
- ES Goers
- ET Wang
- ET Wang
- EY Osman
- F Melchers
- F Wang
- FALM Eskens
- G Lamson
- G Lev-Maor
- G Magistrelli
- G McClorey
- G Pintucci
- G Yeo
- H Bierne
- H Cheng
- H Domdey
- H Dvinge
- H Dvinge
- H Gallinaro
- H Jung
- H Maatz
- H Wang
- H Yong
- H-Y Wang
- HC DeGrendele
- HE Bryant
- HR Hernandez-Lopez
- I Evsyukova
- I Meininger
- IS Trowbridge
- J Bao
- J Bauman
- J Cheng
- J Derbinski
- J Giudice
- J Giudice
- J Guo
- J Häsler
- J Merkin
- J Okuda
- J Rogers
- J Solana
- J Ule
- J Ule
- J Wang
- J Woolard
- J Xu
- J Yang
- J-A Lee
- J-H Kim
- JA Calarco
- JC Leggere
- JC Shultz
- JD Topp
- JE Lee
- JG Conboy
- JK Nussbacher
- JM Izquierdo
- JM Izquierdo
- JM Simon
- JP Venables
- JP Venables
- JR Tollervey
- JW Harbour
- JY Ip
- KK Kim
- KS Sciabica
- KW Lynch
- L Cartegni
- L Chen
- L Conti De
- L Du
- L Klein
- L Saucedo
- L Sedlackova
- L Traunmüller
- L. M. Gallego-Paez
- LB Motta-Mena
- LH Boise
- LS Young
- LT Chow
- LT Gehman
- M Ajiro
- M Danan-Gotthold
- M Danan-Gotthold
- M Fardilha
- M Gigli
- M Hafner
- M Irimia
- M Ladomery
- M Llorian
- M Martin
- M McFarlane
- M Merkenschlager
- M Minnich
- M Pistoni
- M Polymenidou
- M Preussner
- M Ryan
- M Salton
- M Sammeth
- M Ver Heyen
- M Yano
- M Zahid
- M. Ascensão-Ferreira
- M. C. Bordone
- MA Garcia-Blanco
- MA Havens
- MA Havens
- MA Jensen
- MB Coelho
- MB Warf
- MD Diaz-Muñoz
- MF Krummel
- MG Rosenfeld
- MG Rosenfeld
- MJ Benson
- MJ Mallory
- MJ Moore
- MK Oaks
- MK O’Bryan
- MM Scotti
- MP Paronetto
- MP Paronetto
- MR Cookson
- MR Lerner
- MS Anderson
- N Charlet-B
- N Droin
- N Hamada
- N Iwamori
- N Keppetipola
- N Martínez-Montiel
- N-T Chiou
- N. L. Barbosa-Morais
- N. Saraiva-Agostinho
- NA Olshavsky
- NL Barbosa-Morais
- NM Martinez
- NN Singh
- NS Foulkes
- O Anczuków
- O Anczuków
- O Kelemen
- O Muhlemann
- O Rossbach
- P Early
- P Early
- P Tucker
- PA Merwe van der
- PC Beverley
- PC Beverley
- PD Stenson
- PL Boutz
- PW Gunning
- Q Li
- R Aprianto
- R Arch
- R Ashwal-Fluss
- R Benabdillah
- R Jia
- R Karni
- R Klinck
- R Lambrot
- R Reed
- R Schmid
- R Spellman
- R Sperling
- RA Padgett
- RF Luco
- RM Sandri-Goldin
- RP House
- RS Savkur
- RW Ching
- S Alsafadi
- S Berto
- S Bonomi
- S Carpenter
- S Fletcher
- S Gueroussov
- S Leu
- S Oberdoerffer
- S Oltean
- S Ramalingam
- S Rosenberger
- S Shen
- S Zheng
- SD Wagner
- SE Butcher
- SF Nagueh
- SM Berget
- SM Dehm
- SM Rueter
- SM Weyn-Vanhentenryck
- SP Wongpalee
- SV Graham
- SV Kozyrev
- T Fukuhara
- T Hermann
- T Iijima
- T Iijima
- T Nojima
- T Stiewe
- TH Ho
- TM Miller
- TR Webb
- TY-T Hsu
- U Rosani
- V Cognata La
- V Gonçalves
- V Runfola
- VR Moulton
- W Gilbert
- W Guo
- W Liu
- W Xia
- W Zhong
- WR Jeck
- X-D Fu
- Y Barash
- Y Kanemori
- Y Kanemori
- Y Ohshima
- Y Onouchi
- Y Wang
- Y Xue
- Y Zhang
- Y-H Goo
- Y-S Lin
- YS Tsai
- Z Xu
- ZM Zheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Measurement of the inclusive and differential Higgs boson production cross sections in the decay mode to a pair of τ Leptons in pp collisions at sqrt[s]=13 TeV
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdalla H
- Abdelalim AA
- Abdullin S
- Abercrombie D
- Abreu A
- Acharya H
- Acosta D
- Adam W
- Adamidis K
- Adams E
- Adams MR
- Adams T
- Addesa FM
- Adloff C
- Adzic P
- Afanasiev S
- Agapitos A
- Agarwal G
- Aggleton R
- Agram J-L
- Aguilar-Benitez M
- Ahmad A
- Ahmad M
- Ahmed A
- Ahuja S
- Aime' C
- Akchurin N
- Akgun B
- Akpinar A
- Albergo S
- Albert A
- Albrecht S
- Albrow M
- Alcaraz Maestre J
- Aldaya Martin M
- Aldá Júnior WL
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Alison J
- Almond J
- Alpana K
- Alvarez Gonzalez B
- Alverson G
- Alves Gallo Pereira M
- Alves GA
- Aly R
- Alyari M
- Amapane N
- Ambrozas M
- Amendola C
- Amin N
- Amram O
- Amsler C
- An S
- An Y
- Anagnostou G
- Andrea J
- Andreassi G
- Andreev V
- Andreev Y
- Andrejkovic JW
- Andrews MB
- Androsov K
- Anguiano J
- Antchev G
- Anthony D
- Antunovic Z
- Apollinari G
- Apparu D
- Appelt E
- Apresyan A
- Apyan A
- Araujo M
- Arcaro D
- Arcidiacono R
- Arenton MW
- Argiro S
- Arneodo M
- Aruta C
- Asavapibhop B
- Asawatangtrakuldee C
- Asenov P
- Asghar MI
- Asilar E
- Askew A
- Asmuss P
- Atakisi IO
- Attikis A
- Auffray E
- Aushev T
- Auzinger G
- Avati V
- Avery P
- Avila C
- Awais A
- Awan MIM
- Ayala E
- Ayala G
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
- Baarmand MM
- Babaev A
- Bacchetta N
- Bachiller I
- Bachtis M
- Backhaus M
- Baden A
- Baechler J
- Bagliesi G
- Bahinipati S
- Baillon P
- Bainbridge R
- Bakas G
- Bakhshiansohi H
- Bakshi AS
- Baldenegro Barrera C
- Ban Y
- Band R
- Bandyopadhyay H
- Banerjee S
- Banerjee S
- Bansal S
- Barbagli G
- Barberis E
- Bargassa P
- Baringer P
- Barnes VE
- Barney D
- Baron O
- Barria P
- Barrio Luna M
- Barroso Ferreira Filho M
- Bartek R
- Bartosik N
- Bartók M
- Bastos D
- Battilana C
- Baty A
- Bauer G
- Bauerdick LAT
- Baxter S
- Bayatmakou M
- Bayshev I
- Bean A
- Beauceron S
- Beaudette F
- Becerril Gonzalez H
- Bechtel J
- Bedoya CF
- Beghin D
- Behera PK
- Behera SC
- Behnke O
- Bein S
- Belforte S
- Bell KW
- Bellan R
- Belloni A
- Bellora A
- Belyaev A
- Belyaev A
- Benaglia A
- Benato L
- Bencze G
- Bendavid J
- Benecke A
- Benelli G
- Benitez JF
- Benussi L
- Berenguer Antequera J
- Bergauer T
- Berger P
- Beri SB
- Bermúdez Martínez A
- Bernardes CA
- Bernet C
- Berry D
- Berryhill J
- Bertacchi V
- Besancon M
- Bestintzanos I
- Bethani A
- Beyrouthy T
- Bhal E
- Bhardwaj A
- Bharthuar S
- Bharti M
- Bhat PC
- Bhatnagar V
- Bhattacharya R
- Bhattacharya S
- Bhattacharya S
- Bhattacharya S
- Bhowmik D
- Bhowmik S
- Bhyun JH
- Bi R
- Bialkowska H
- Bianchini L
- Bianco M
- Bianco S
- Biino C
- Bilei GM
- Bilin B
- Bin Anuar AA
- Bin Norjoharuddeen N
- Bisello D
- Black K
- Blekman F
- Blinov V
- Bloch D
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Boccali T
- Bocci A
- Bodek A
- Boimska B
- Boldrini G
- Boletti A
- Bologna S
- Bols ES
- Bonacorsi D
- Bonanomi M
- Bonham B
- Bonilla J
- Bonomally S
- Boos E
- Boran F
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- Bornheim A
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- Borshch V
- Bortignon P
- Bose T
- Bossini E
- Botta C
- Botta V
- Boudoul G
- Bouhali O
- Bourgatte G
- Bourilkov D
- Bozzo M
- Bragagnolo A
- Braghieri A
- Brainerd C
- Brandao Malbouisson H
- Brandt S
- Branson JG
- Breedon R
- Breeze S
- Brew C
- Bright-Thonney S
- Brigliadori L
- Brigljevic V
- Brinkerhoff A
- Brivio F
- Brochero Cifuentes JA
- Brom J-M
- Brommer S
- Brooke JJ
- Brown RM
- Brunner D
- Bruno G
- Bryant P
- Bryson M
- Brzhechko D
- Brücken E
- Bucci R
- Buccilli A
- Buchmuller O
- Buchot Perraguin A
- Budkouski D
- Bueghly J
- Bundock A
- Bunichev V
- Bunkowski K
- Buontempo S
- Burkett K
- Burkle B
- Burt K
- Bury F
- Busson P
- Busza W
- Butalla S
- Butler JN
- Butler PH
- Butz E
- Bylinkin A
- Bylsma B
- Bärtschi P
- Cabrera A
- Cabrillo IJ
- Cadamuro L
- Caillol C
- Cakir A
- Calandri A
- Calderon De La Barca Sanchez M
- Calderon A
- Cali IA
- Calligaris L
- Calzaferri S
- Camen C
- Caminada L
- Campagnari C
- Campana M
- Campanini R
- Campbell A
- Camporesi T
- Candelise V
- Canelli MF
- Canepa A
- Cankocak K
- Capeans Garrido M
- Capiluppi P
- Cappati A
- Caputo C
- Caraway B
- Cardini A
- Cardwell B
- Carle A
- Carlin R
- Carnevali F
- Carrera Jarrin E
- Carrillo Montoya CA
- Carrillo Moreno S
- Cartiglia N
- Carvalho Antunes De Oliveira A
- Carvalho W
- Casarsa M
- Caspart R
- Cassese A
- Castaldi R
- Castaneda Hernandez A
- Castilla-Valdez H
- Castro A
- Cavallari F
- Cavallo FR
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- Cavanaugh R
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- Ceccarelli R
- Cepaitis V
- Cepeda M
- Cerati GB
- Cerci S
- Cerminara G
- Cerrada M
- Cerri O
- Cetorelli F
- Chabert EC
- Chadeeva M
- Chahal GS
- Chang P
- Chanon N
- Chao Y
- Chapon E
- Charlot C
- Chatterjee RM
- Chatterjee S
- Chaudhary G
- Chauhan S
- Chauhan S
- Chawla R
- Checchia P
- Chekhovsky V
- Chen C
- Chen GM
- Chen HS
- Chen KF
- Chen M
- Chen PH
- Chen X
- Chen Y
- Chen Y
- Chen Z
- Chenarani S
- Cheng C
- Cheng T
- Cheng Y
- Cherepanov V
- Chernyavskaya N
- Chertok M
- Cheung HWK
- Chhibra SS
- Chiarito B
- Chinellato J
- Chlebana F
- Cho S
- Choi J
- Choi M
- Choi S
- Chou JP
- Choudhary BC
- Choudhury S
- Christoforou K
- Chudasama R
- Chwalek T
- Ciangottini D
- Ciocci MA
- Cipriani M
- Citron M
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clement E
- Clerbaux B
- CMS Collaboration
- Cockerill DJA
- Colaleo A
- Coldham K
- Cole JE
- Colino N
- Collard C
- Colling D
- Colombina F
- Cometti S
- Connor P
- Consuegra Rodríguez S
- Contardo D
- Conway J
- Cooke C
- Cooper SI
- Cooperstein S
- Corcodilos L
- Cormier K
- Cornelis T
- Correia Silva G
- Cosby C
- Cossutti F
- Costa M
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- Coubez X
- Couderc F
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- Covarelli R
- Cox B
- Cox PT
- Cranshaw DJ
- Creanza D
- Cremonesi M
- Cristella L
- Csanad M
- Csorgo T
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cummings G
- Cussans D
- Cutts D
- Czellar S
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- D'Alfonso M
- D'Amante V
- D'Enterria D
- D'Hondt J
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- Da Rold A
- Da Silveira GG
- Dabrowski A
- Dalchenko M
- Dallavalle GM
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- Danilov V
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- Darwish MR
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- Dasu S
- Datta A
- Dauncey P
- David A
- David P
- Davies G
- Davignon O
- Davis J
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- De Guio F
- De Iorio A
- De Jesus Damiao D
- De La Cruz B
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- De Lentdecker G
- De Leo K
- De Palma M
- De Roeck A
- De Silva M
- De Trocóniz JF
- De Wit A
- De Wolf EA
- Decaro M
- Deelen N
- Defranchis MM
- Deile M
- Dejardin M
- Del Burgo R
- Del Re D
- Delaere C
- Delannoy AG
- Delcourt M
- Delgado Peris A
- Delgado A
- Dell'Orso R
- Della Negra M
- Della Ricca G
- Demaria N
- Demina R
- Demiragli Z
- Demiroglu ZS
- Denegri D
- Depasse P
- Dermenev A
- Dev N
- Dewanjee RK
- Dezoort G
- Dharmaratna WGD
- Dhingra N
- Di Croce D
- Di Domenico MR
- Di Florio A
- Di Marco E
- Di Mattia A
- Di Petrillo KF
- Di Pilato A
- Diab B
- Diamantopoulou M
- Diaz D
- Didukh L
- Diemoz M
- Dierlamm A
- Dildick S
- Dilsiz K
- Dimitrov A
- Dimova T
- Dinardo ME
- Dini P
- Diotalevi T
- Dissertori G
- Dittmann J
- Dittmar M
- Dittmer S
- Dobson M
- Dobur D
- Dodonova A
- Dogra S
- Dolek F
- Dolen J
- Dominguez A
- Donato S
- Donegà M
- Donertas IS
- Dordevic M
- Dorfer C
- Dorigo T
- Doroba K
- Dorsett A
- Dosselli U
- Dozen C
- Dragicevic M
- Dremin I
- Droll A
- Duarte Campderros J
- Duarte J
- Dube S
- Dubinin M
- Dudko L
- Dugad S
- Dulemba JL
- Dumanoglu I
- Dupont N
- Duric S
- Durkin LS
- Dutta D
- Dutta I
- Dutta S
- Dutta S
- Dutta V
- Dziwok C
- Dünser M
- Eble F
- Ebrahimi A
- Eckerlin G
- Ecklund KM
- Eckstein D
- Eerola P
- Ehataht K
- Eich M
- El Faham H
- El Mamouni H
- El Morabit K
- Eliseev D
- Elkafrawy T
- Elliott-Peisert A
- Ellis KV
- Elmer P
- Elmetenawee W
- Elumakhov D
- Elvira VD
- Eminizer M
- Emriskova N
- Eno SC
- Epshteyn V
- Erbacher R
- Erdmann M
- Erdmann W
- Erice C
- Erodotou E
- Errico F
- Ershov A
- Escalante Del Valle A
- Eskut E
- Estevez Banos LI
- Etesami SM
- Eusebi R
- Evangelou I
- Evans A
- Evdokimov O
- Everaerts P
- Eysermans J
- Fabbri F
- Fabozzi F
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- Fallavollita F
- Fallon C
- Falmagne G
- Faltermann N
- Fanfani A
- Fangmeier C
- Fanò L
- Farkas K
- Fasanella D
- Faure JL
- Favart L
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- Fayer S
- Fedi G
- Feindt F
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- Feng Y
- Ferbel T
- Ferencek D
- Ferguson T
- Fernandez Madrazo C
- Fernandez Menendez J
- Fernandez M
- Fernández Manteca PJ
- Fernández Ramos JP
- Ferri F
- Ferro F
- Field RD
- Fienga F
- Filatov O
- Finco L
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- Finger M
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- Fiorendi S
- Fiorina D
- Fischer B
- Flacher H
- Flix J
- Florent A
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- Flügge G
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- Folgueras S
- Fonseca De Souza S
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- Zecchinelli AG
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- Zeuner WD
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- Zorbilmez C
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- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Álvarez Fernández A
- Özçelik Ö
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
Measurements of the inclusive and differential fiducial cross sections of the Higgs boson are presented, using the τ lepton decay channel. The differential cross sections are measured as functions of the Higgs boson transverse momentum, jet multiplicity, and transverse momentum of the leading jet in the event, if any. The analysis is performed using proton-proton collision data collected with the CMS detector at the LHC at a center-of-mass energy of 13 TeV and corresponding to an integrated luminosity of 138 fb^{-1}. These are the first differential measurements of the Higgs boson cross section in the final state of two τ leptons. In final states with a large jet multiplicity or with a Lorentz-boosted Higgs boson, these measurements constitute a significant improvement over measurements performed in other final states
Reconstruction of the pollution history of alkylphenols (4-tert-octylphenol, 4-nonylphenol) in the Baltic Sea
- Author
- A Arditsoglou
- A David
- A Lewandowska
- A Szmytkiewicz
- AB Hansen
- AM Soto
- Anonymous
- Anonymous
- B Chen
- Bożena Graca
- D Schlenk
- Danuta Zakrzewska
- DM John
- DW McLeese
- F Wulff
- G Pojana
- GG Ying
- GG Ying
- H Fiege
- H Kumata
- HELCOM
- HELCOM
- I Koniecko
- J Carstensen
- J Eckhéll
- J Milinovič
- J Warzocha
- JA Robbins
- JL Zhou
- JS Khim
- K Bester
- K Jahan
- K Senthil Kumar
- L Håkanson
- L Håkanson
- L Nunez
- LJ Heinis
- LM Mayer
- M Ahel
- M Ahel
- M Hansson
- M Petrovic
- M Staniszewska
- M Staniszewska
- M Suplińska
- Marta Staniszewska
- MC Chuan
- MHI Comber
- N Jonkers
- OSPAR
- P Jonsson
- P Jonsson
- P Jonsson
- PA Lara-Martin
- PC Metre Van
- PG Appleby
- PL Ferguson
- PR Bierman
- R Ebinghaus
- R Kurihara
- R Loos
- S Blomqvist
- S Jobling
- S Jobling
- SH Fonselius
- T Isobe
- T Zalewska
- Tamara Zalewska
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- …