Fatal Rickettsia conorii subsp. israelensis Infection, Israel

Fatal Rickettsia conorii subsp. israelensis Infection, Israe

Random Matrix Theories in Quantum Physics: Common Concepts

We review the development of random-matrix theory (RMT) during the last decade. We emphasize both the theoretical aspects, and the application of the theory to a number of fields. These comprise chaotic and disordered systems, the localization problem, many-body quantum systems, the Calogero-Sutherland model, chiral symmetry breaking in QCD, and quantum gravity in two dimensions. The review is preceded by a brief historical survey of the developments of RMT and of localization theory since their inception. We emphasize the concepts common to the above-mentioned fields as well as the great diversity of RMT. In view of the universality of RMT, we suggest that the current development signals the emergence of a new "statistical mechanics": Stochasticity and general symmetry requirements lead to universal laws not based on dynamical principles.Comment: 178 pages, Revtex, 45 figures, submitted to Physics Report

Semitic Dialects and Dialectology

Characterised by the multiplicity and diversity of research and methodology, the European tradition of Semitic linguistics has always supported fieldwork and highly valued the data obtained in this way as it allows to create an interesting dynamic for linguistic studies itself. In the spirit of this tradition and to uphold it, the present book is a collection of articles based on data gathered primarily during field research expeditions. The volume is divided into two parts—Studies on various specific linguistic issues and Texts containing previously unpublished transcriptions of audio recordings in Arabic dialects, Maltese and Jibbali/Shehret.Die europäische Tradition der semitischen Linguistik, die sich durch Vielfalt der Forschungsmethoden auszeichnet, hat dialektologische Feldforschung immer hoch geschätzt, da die gewonnenen Sprachaufnahmen im Kontext der älteren Sprachformen gesetzt werden und somit eine hochgradig interessante Dynamik in der Sprachwissenschaft ermöglichen. Im Geiste dieser Tradition und um sie aufrechtzuerhalten, ist das vorliegende Buch eine Sammlung von Artikeln, deren Daten vor allem während der Feldforschung gesammelt wurden. Der Band gliedert sich in zwei Teile - Studien zu verschiedenen spezifischen linguistischen Fragestellungen und Texte mit bisher unveröffentlichten Transkriptionen von Audioaufnahmen in arabischen Dialekten, Maltesisch und Jibbali/Shehret

Structural modifications of the Ω loop in human acetylcholinesterase

AbstractConformational mobility of the surface Ω loop (Cys-69-Cys-96) in human acetylcholinesterase (HuAChE) was recently implicated in substrate accessibility to the active center and in the mechanism of allosteric modulation of enzymatic activity. We therefore generated and kinetically evaluated the following modifications or replacements in HuAChE: (a) residues at the loop ends, (b) residues involved in putative hydrogen-bond interactions within the loop and between the loop and the protein core, (c) ChEs conserved proline residues within the loop and (d) a deletion of a conserved segment of 5 residues. All the residue replacements, including those of the prolines, had either limited or no effect on enzyme reactivity. These results suggest that unlike the case of lipase, the Ω loop in the HuAChE is not involved in large lid-like displacements. In cases where modifications of the loop sequence had some effect on reactivity, the effects could be attributed to an altered position of residue Trp-86 supporting the proposed coupling between the structure of the Ω loop and the positioning of the Trp-86 indole moiety, in catalytic activity and in allosterism

Semitic Dialects and Dialectology

Characterised by the multiplicity and diversity of research and methodology, the European tradition of Semitic linguistics has always supported fieldwork and highly valued the data obtained in this way as it allows to create an interesting dynamic for linguistic studies itself. In the spirit of this tradition and to uphold it, the present book is a collection of articles based on data gathered primarily during field research expeditions. The volume is divided into two parts—Studies on various specific linguistic issues and Texts containing previously unpublished transcriptions of audio recordings in Arabic dialects, Maltese and Jibbali/Shehret