Co-Variation of Tonality in the Music and Speech of Different Cultures

Whereas the use of discrete pitch intervals is characteristic of most musical traditions, the size of the intervals and the way in which they are used is culturally specific. Here we examine the hypothesis that these differences arise because of a link between the tonal characteristics of a culture's music and its speech. We tested this idea by comparing pitch intervals in the traditional music of three tone language cultures (Chinese, Thai and Vietnamese) and three non-tone language cultures (American, French and German) with pitch intervals between voiced speech segments. Changes in pitch direction occur more frequently and pitch intervals are larger in the music of tone compared to non-tone language cultures. More frequent changes in pitch direction and larger pitch intervals are also apparent in the speech of tone compared to non-tone language cultures. These observations suggest that the different tonal preferences apparent in music across cultures are closely related to the differences in the tonal characteristics of voiced speech

Terrace reconstruction and long profile projection: a case study from the Solent river system near Southampton, England

River terrace sequences are important frameworks for archaeological evidence and as such it is important to produce robust correlations between what are often fragmentary remnants of ancient terraces. This paper examines both conceptual and practical issues related to such correlations, using a case study from the eastern part of the former Solent River system near Southampton, England. In this region two recent terrace schemes have been constructed using different data to describe the terrace deposits: one based mainly on terrace surfaces; the other on gravel thicknesses, often not recording the terrace surface itself. The utility of each of these types of data in terrace correlation is discussed in relation to the complexity of the record, the probability of post-depositional alteration of surface sediments and comparison of straight-line projections with modern river long profiles. Correlation using age estimates is also discussed, in relation to optically-stimulated luminescence dating of sand lenses within terrace gravels in this region during the PASHCC project. It is concluded that the need for replication at single sites means that this approach has limited use for correlative purposes, although dating of sediments is important for understanding wider landscape evolution and patterns of human occupation

A Multi-Wavelength Study of Low Redshift Cluster of Galaxies II. Environmental Impact on Galaxy Growth

Galaxy clusters provide powerful laboratories for the study of galaxy evolution, particularly the origin of correlations of morphology and star formation rate (SFR) with density. We construct visible to MIR spectral energy distributions (SEDs) of cluster galaxies and use them to measure stellar masses and SFRs in eight low redshift clusters, which we examine as a function of environment. A partial correlation analysis indicates that SFR depends strongly on R/R200 (>99.9% confidence) and is independent of projected local density at fixed radius. SFR also shows no residual dependence on stellar mass. We therefore conclude that interactions with the intra-cluster medium drive the evolution of SFRs in cluster galaxies. A merged sample of galaxies from the five most complete clusters shows \propto(R/R200)^(1.3+/-0.7) for galaxies with R/R200<0.4. A decline in the fraction of SFGs toward the cluster center contributes most of this effect, but it is accompanied by a reduction in SFRs among star-forming galaxies (SFGs) near the cluster center. The increase in the fraction of SFGs toward larger R/R200 and the isolation of SFGs with reduced SFRs near the cluster center are consistent with ram pressure stripping as the mechanism to truncate star formation in galaxy clusters. We conclude that stripping drives the properties of SFGs over the range of radii we examine. We also find that galaxies near the cluster center are more massive than galaxies farther out in the cluster at ~3.5\sigma, which suggests that cluster galaxies experience dynamical relaxation during the course of their evolution.Comment: 22 ApJ pages, 11 figures. Submitted to Ap

Mergers, AGN, and 'Normal' Galaxies: Contributions to the Distribution of Star Formation Rates and Infrared Luminosity Functions

We use a novel method to predict the contribution of normal star-forming galaxies, merger-induced bursts, and obscured AGN, to IR luminosity functions (LFs) and global SFR densities. We use empirical halo occupation constraints to populate halos with galaxies and determine the distribution of normal and merging galaxies. Each system can then be associated with high-resolution hydrodynamic simulations. We predict the distribution of observed luminosities and SFRs, from different galaxy classes, as a function of redshift from z=0-6. We provide fitting functions for the predicted LFs, quantify the uncertainties, and compare with observations. At all redshifts, 'normal' galaxies dominate the LF at moderate luminosities ~L* (the 'knee'). Merger-induced bursts increasingly dominate at L>>L*; at the most extreme luminosities, AGN are important. However, all populations increase in luminosity at higher redshifts, owing to increasing gas fractions. Thus the 'transition' between normal and merger-dominated sources increases from the LIRG-ULIRG threshold at z~0 to bright Hyper-LIRG thresholds at z~2. The transition to dominance by obscured AGN evolves similarly, at factor of several higher L_IR. At all redshifts, non-merging systems dominate the total luminosity/SFR density, with merger-induced bursts constituting ~5-10% and AGN ~1-5%. Bursts contribute little to scatter in the SFR-stellar mass relation. In fact, many systems identified as 'ongoing' mergers will be forming stars in their 'normal' (non-burst) mode. Counting this as 'merger-induced' star formation leads to a stronger apparent redshift evolution in the contribution of mergers to the SFR density.Comment: 16 pages, 9 figures (+appendices), accepted to MNRAS. A routine to return the galaxy merger rates discussed here is available at http://www.cfa.harvard.edu/~phopkins/Site/mergercalc.htm

A new method for classifying galaxy SEDs from multiwavelength photometry

We present a new method to classify the broad-band optical–near-infrared spectral energy distributions (SEDs) of galaxies using three shape parameters (super-colours) based on a principal component analysis of model SEDs. As well as providing a compact representation of the wide variety of SED shapes, the method allows for easy visualization of information loss and biases caused by the incomplete sampling of the rest-frame SED as a function of redshift. We apply the method to galaxies in the United Kingdom Infrared Telescope Infrared Deep Sky Survey Ultra Deep Survey with 0.9 11, declining steadily to 13 per cent at logM∗/M_ = 10. The properties and mass function of the poststarburst galaxies are consistent with a scenario in which gas-rich mergers contribute to the growth of the low- and intermediate-mass range of the red sequence

Disability activism and the politics of scale

In this paper, we examine the role of spatial scale in mediating and shaping political struggles between disabled people and the state. Specifically, we draw on recent theoretical developments concerning the social construction of spatial scale to interpret two case studies of disability activism within Canada and Ireland. In particular, we provide an analysis of how successful the disability movement in each locale has been at 'jumping scale' and enacting change, as well as examining what the consequences of such scaling-up have been for the movement itself. We demonstrate that the political structures operating in each country markedly affect the scaled nature of disability issues and the effectiveness of political mobilization at different scales

Genetic mechanisms of critical illness in COVID-19.

Host-mediated lung inflammation is present1, and drives mortality2, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development3. Here we report the results of the GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2,244 critically ill patients with COVID-19 from 208 UK intensive care units. We have identified and replicated the following new genome-wide significant associations: on chromosome 12q24.13 (rs10735079, P = 1.65 × 10-8) in a gene cluster that encodes antiviral restriction enzyme activators (OAS1, OAS2 and OAS3); on chromosome 19p13.2 (rs74956615, P = 2.3 × 10-8) near the gene that encodes tyrosine kinase 2 (TYK2); on chromosome 19p13.3 (rs2109069, P = 3.98 ×  10-12) within the gene that encodes dipeptidyl peptidase 9 (DPP9); and on chromosome 21q22.1 (rs2236757, P = 4.99 × 10-8) in the interferon receptor gene IFNAR2. We identified potential targets for repurposing of licensed medications: using Mendelian randomization, we found evidence that low expression of IFNAR2, or high expression of TYK2, are associated with life-threatening disease; and transcriptome-wide association in lung tissue revealed that high expression of the monocyte-macrophage chemotactic receptor CCR2 is associated with severe COVID-19. Our results identify robust genetic signals relating to key host antiviral defence mechanisms and mediators of inflammatory organ damage in COVID-19. Both mechanisms may be amenable to targeted treatment with existing drugs. However, large-scale randomized clinical trials will be essential before any change to clinical practice