5 research outputs found

    Shape of an elastica under growth restricted by friction

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    We investigate the quasi-static growth of elastic fibers in the presence of dry or viscous friction. An unusual form of destabilization beyond a critical length is described. In order to characterize this phenomenon, a new definition of stability against infinitesimal perturbations over finite time intervals is proposed and a semi-analytical method for the determination of the critical length is developed. The post-critical behavior of the system is studied by using an appropriate numerical scheme based on variational methods. We find post-critical shapes for uniformly distributed as well as for concentrated growth and demonstrate convergence to a figure-8 shape for large lengths when self-crossing is allowed. Comparison with simple physical experiments yields reasonable accuracy of the theoretical predictions

    Shape of an elastica under growth restricted by friction

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    We investigate the quasi-static growth of elastic fibers in the presence of isotropic dry or viscous friction. An unusual form of destabilization beyond a critical length is described. In order to characterize this phenomenon, a new definition of stability against infinitesimal perturbations over finite time intervals is proposed and a semi-analytical method for the determination of the critical length is developed. The post-critical behavior of the system is studied by using an appropriate numerical scheme based on variational methods. We find post-critical shapes for uniformly distributed as well as for concentrated growth and demonstrate convergence to a figure 8 shape for large lengths when self-crossing is allowed. Comparison with simple physical experiments yields reasonable accuracy of the theoretical predictions

    Quantitative Analysis of Inflammatory Uterine Lesions of Pregnant Gilts with Digital Image Analysis Following Experimental PRRSV-1 Infection

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    Reproductive disorders caused by porcine reproductive and respiratory syndrome virus-1 are not yet fully characterized. We report QuPath-based digital image analysis to count inflammatory cells in 141 routinely, and 35 CD163 immunohistochemically stained endometrial slides of vaccinated or unvaccinated pregnant gilts inoculated with a high or low virulent PRRSV-1 strain. To illustrate the superior statistical feasibility of the numerical data determined by digital cell counting, we defined the association between the number of these cells and endometrial, placental, and fetal features. There was strong concordance between the two manual scorers. Distributions of total cell counts and endometrial and placental qPCR results differed significantly between examiner1\u27s endometritis grades. Total counts\u27 distribution differed significantly between groups, except for the two unvaccinated. Higher vasculitis scores were associated with higher endometritis scores, and higher total cell counts were expected with high vasculitis/endometritis scores. Cell number thresholds of endometritis grades were determined. A significant correlation between fetal weights and total counts was shown in unvaccinated groups, and a significant positive correlation was found between these counts and endometrial qPCR results. We revealed significant negative correlations between CD163+ counts and qPCR results of the unvaccinated group infected with the highly virulent strain. Digital image analysis was efficiently applied to assess endometrial inflammation objectively

    The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project

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    The PREDICTS project—Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)—has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3.2 million records sampled at over 26,000 locations and representing over 47,000 species. We outline how the database can help in answering a range of questions in ecology and conservation biology. To our knowledge, this is the largest and most geographically and taxonomically representative database of spatial comparisons of biodiversity that has been collated to date; it will be useful to researchers and international efforts wishing to model and understand the global status of biodiversity
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