El arte humanizado y la crítica cinematográfica de Jaime Torres Bodet y César Vallejo

This study analyzes the concept of Vanguard art of Jaime Torres Bodet and César Vallejo, as defined in their articles on silent film and their literary works. Both authors share a love of silent film, and their ideas about modern art have much in common, since both contend that true Vanguard art always possesses a deeply human quality. According to Torres Bodet, the velocity and artificiality of silent film are dazzling, energizing, and sometimes dangerous for Vanguard artists. In the silent films of Charlie Chaplin, Sergei Eisenstein, and Dziga Vertov, Vallejo finds an artificiality and a velocity that have been transformed into an admirable expression of the human condition

Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates.

Among novel compounds under recent investigation as potential new antimalarial drugs are three independently developed inhibitors of the Plasmodium falciparum P-type ATPase (PfATP4): KAE609 (cipargamin), PA92, and SJ733. We assessed ex vivo susceptibilities to these compounds of 374 fresh P. falciparum isolates collected in Tororo and Busia districts, Uganda, from 2016 to 2019. Median IC50s were 65 nM for SJ733, 9.1 nM for PA92, and 0.5 nM for KAE609. Sequencing of pfatp4 for 218 of these isolates demonstrated many nonsynonymous single nucleotide polymorphisms; the most frequent mutations were G1128R (69% of isolates mixed or mutant), Q1081K/R (68%), G223S (25%), N1045K (16%), and D1116G/N/Y (16%). The G223S mutation was associated with decreased susceptibility to SJ733, PA92, and KAE609. The D1116G/N/Y mutations were associated with decreased susceptibility to SJ733, and the presence of mutations at both codons 223 and 1116 was associated with decreased susceptibility to PA92 and SJ733. In all of these cases, absolute differences in susceptibilities of wild-type (WT) and mutant parasites were modest. Analysis of clones separated from mixed field isolates consistently identified mutant clones as less susceptible than WT. Analysis of isolates from other sites demonstrated the presence of the G223S and D1116G/N/Y mutations across Uganda. Our results indicate that malaria parasites circulating in Uganda have a number of polymorphisms in PfATP4 and that modestly decreased susceptibility to PfATP4 inhibitors is associated with some mutations now present in Ugandan parasites

Herbivore-Mediated Effects of Glucosinolates on Different Natural Enemies of a Specialist Aphid

The cabbage aphid Brevicoryne brassicae is a specialist herbivore that sequesters glucosinolates from its host plant as a defense against its predators. It is unknown to what extent parasitoids are affected by this sequestration. We investigated herbivore-mediated effects of glucosinolates on the parasitoid wasp Diaeretiella rapae and the predator Episyrphus balteatus. We reared B. brassicae on three ecotypes of Arabidopsis thaliana that differ in glucosinolate content and on one genetically transformed line with modified concentrations of aliphatic glucosinolates. We tested aphid performance and the performance and behavior of both natural enemies. We correlated this with phloem and aphid glucosinolate concentrations and emission of volatiles. Brevicoryne brassicae performance correlated positively with concentrations of both aliphatic and indole glucosinolates in the phloem. Aphids selectively sequestered glucosinolates. Glucosinolate concentration in B. brassicae correlated negatively with performance of the predator, but positively with performance of the parasitoid, possibly because the aphids with the highest glucosinolate concentrations had a higher body weight. Both natural enemies showed a positive performance-preference correlation. The predator preferred the ecotype with the lowest emission of volatile glucosinolate breakdown products in each test combination, whereas the parasitoid wasp preferred the A. thaliana ecotype with the highest emission of these volatiles. The study shows that there are differential herbivore-mediated effects of glucosinolates on a predator and a parasitoid of a specialist aphid that selectively sequesters glucosinolates from its host plant

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

Un vagabundo revolucionario y antimaterialista: Charlot en Don Quijote de Hollywood de Luis Felipe Rodríguez (Cuba, 1936)

This article proposes to analyze, through a close reading of the novel Don Quijote de Hollywood by Luis Felipe Rodríguez, how the author blends two contrasting versions of Chaplin’s Tramp character in this literary rendering of Charlot: the empathic hero described by practitioners of humanist avant-garde, and the hero who fights against bourgeois culture. Our goal is to point out how Rodríguez adapts specific scenes from the film City Lights (Charles Chaplin, 1931) in order to create an original and hybrid protagonist, a humanized cinematic idol, a Marxist revolutionary manufactured in a Hollywood studio.Keywords: history of media, silent film, literature, Cuba, Chaplin. ___________Un vagabundo revolucionario y antimaterialista. Charlot en la novela Don Quijote de Hollywood de Luis Felipe Rodríguez (Cuba, 1936)Resumen: Este artículo propone analizar, a través de una minuciosa lectura de la novela Don Quijote de Hollywood de Luis Felipe Rodríguez, cómo el autor fusiona dos versiones contrastantes del personaje del Vagabundo de Chaplin: el héroe empático descrito por los practicantes de una vanguardia humanista y el héroe que lucha contra la cultura burguesa. Nuestro objetivo es señalar cómo Rodríguez adapta escenas específicas de la película City Lights (Luces de la ciudad, Charles Chaplin, 1931) para crear un protagonista original e híbrido, un ídolo cinematográfico humanizado, un revolucionario fabricado en un estudio de Hollywood.Palabras clave: historia de los medios, cine mudo, literatura, Cuba, Chaplin.___________Um vagabundo revolucionário e antimaterialista: Charlot em o romance Don Quijote de Hollywood de Luis Felipe Rodríguez (Cuba, 1936)Resumo: Este artigo se propõe a analisar, por meio de uma leitura atenta do romance Don Quijote de Hollywood de Luis Felipe Rodríguez, como o autor mescla duas versões contrastantes do Vagabundo de Chaplin nesta versão literária de Charlot: o herói empático descrito por praticantes de uma vanguarda humanista e o herói que luta contra a cultura burguesa. Nosso objetivo é apontar como Rodríguez adapta cenas específicas do filme City Lights (Charles Chaplin, 1931) para criar um protagonista original e híbrido, um ídolo cinematográfico humanizado, um revolucionário marxista fabricado em um estúdio de Hollywood.Palavras chave: história da mídia, filmes mudos, literatura, Cuba, Chaplin.___________Date of reception: 20th June 2022Date of acceptance: 18th October 2022___________ ARK CAICYT: http://id.caicyt.gov.ar/ark:/s24690767/a2bbatysbEste artículo propone analizar, a través de una minuciosa lectura de la novela Don Quijote de Hollywood de Luis Felipe Rodríguez, cómo el autor fusiona dos versiones contrastantes del personaje del Vagabundo de Chaplin: el héroe empático descrito por los practicantes de una vanguardia humanista y el héroe que lucha contra la cultura burguesa. Nuestro objetivo es señalar cómo Rodríguez adapta escenas específicas de la película City Lights (Luces de la ciudad, Charles Chaplin, 1931) para crear un protagonista original e híbrido, un ídolo cinematográfico humanizado, un revolucionario fabricado en un estudio de Hollywood.Palabras clave: historia de los medios, cine mudo, literatura, Cuba, Chaplin.___________ A revolutionary and anti-materialistic Tramp: Charlot in the novel Don Quijote de Hollywood by Luis Felipe Rodríguez (Cuba, 1936)Abstract: This article proposes to analyze, through a close reading of the novel Don Quijote de Hollywood by Luis Felipe Rodríguez, how the author blends two contrasting versions of Chaplin’s Tramp character in this literary rendering of Charlot: the empathic hero described by practitioners of humanist avant-garde, and the hero who fights against bourgeois culture. Our goal is to point out how Rodríguez adapts specific scenes from the film City Lights (Charles Chaplin, 1931) in order to create an original and hybrid protagonist, a humanized cinematic idol, a Marxist revolutionary manufactured in a Hollywood studio.Keywords: history of media, silent film, literature, Cuba, Chaplin.___________ Um vagabundo revolucionário e antimaterialista: Charlot em o romance Don Quijote de Hollywood de Luis Felipe Rodríguez (Cuba, 1936)Resumo: Este artigo se propõe a analisar, por meio de uma leitura atenta do romance Don Quijote de Hollywood de Luis Felipe Rodríguez, como o autor mescla duas versões contrastantes do Vagabundo de Chaplin nesta versão literária de Charlot: o herói empático descrito por praticantes de uma vanguarda humanista e o herói que luta contra a cultura burguesa. Nosso objetivo é apontar como Rodríguez adapta cenas específicas do filme City Lights (Charles Chaplin, 1931) para criar um protagonista original e híbrido, um ídolo cinematográfico humanizado, um revolucionário marxista fabricado em um estúdio de Hollywood.Palavras chave: história da mídia, filmes mudos, literatura, Cuba, Chaplin.___________ Fecha de recepción: 20 de junio de 2022Fecha de aceptación: 18 de octubre de 2022___________ ARK CAICYT: http://id.caicyt.gov.ar/ark:/s24690767/a2bbatys

Rural Cooperatives Magazine, January/February 1999

Features- Magazine Overview; The 1930s; The 1940s; The 1950s; The 1960s; The 1970s; The 1980s; The 1990

Rural Cooperatives Magazine, January/February 1999

Features- Magazine Overview; The 1930s; The 1940s; The 1950s; The 1960s; The 1970s; The 1980s; The 1990