Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the field continues to expand and novel mechanisms that orchestrate multiple cell death pathways are unveiled, we propose an updated classification of cell death subroutines focusing on mechanistic and essential (as opposed to correlative and dispensable) aspects of the process. As we provide molecularly oriented definitions of terms including intrinsic apoptosis, extrinsic apoptosis, mitochondrial permeability transition (MPT)-driven necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic cell death, NETotic cell death, lysosome-dependent cell death, autophagy-dependent cell death, immunogenic cell death, cellular senescence, and mitotic catastrophe, we discuss the utility of neologisms that refer to highly specialized instances of these processes. The mission of the NCCD is to provide a widely accepted nomenclature on cell death in support of the continued development of the field

L'Atrazine (évaluation du risque sur la santé et méthode de dosage dans l'eau)

MONTPELLIER-BU Pharmacie (341722105) / SudocSudocFranceF

The Shaman and the Spirits: The Meaning of the Word 'ling' in the Jiuge Poems

In all major dictionaries the first entry for the Chinese word 'ling' is 'shaman' (wu). This meaning of the word is based on Wang Yi's interpretation of two Jiuge poems in the Chuci collection. The present article investigates the possibility of this identification and concludes that there is no evidence to support Wang Yi's opinion. On the other hand, there is ample evidence to suggest that the accepted meanings of ling (spirit, numinous, magical) and the general characteristics of the Chinese shaman are indeed interrelated in many respects