Normalizations of Eisenstein integrals for reductive symmetric spaces

We construct minimal Eisenstein integrals for a reductive symmetric space G/H as matrix coefficients of the minimal principal series of G. The Eisenstein integrals thus obtained include those from the \sigma-minimal principal series. In addition, we obtain related Eisenstein integrals, but with different normalizations. Specialized to the case of the group, this wider class includes Harish-Chandra's minimal Eisenstein integrals.Comment: 66 pages. Minor revisions. To be published in Journal of Functional Analysi

KK-invariant cusp forms for reductive symmetric spaces of split rank one

Let $G/H$ be a reductive symmetric space of split rank $1$ and let $K$ be a maximal compact subgroup of $G$. In a previous article the first two authors introduced a notion of cusp forms for $G/H$. We show that the space of cusp forms coincides with the closure of the $K$-finite generalized matrix coefficients of discrete series representations if and only if there exist no $K$-spherical discrete series representations. Moreover, we prove that every $K$-spherical discrete series representation occurs with multiplicity $1$ in the Plancherel decomposition of $G/H$.Comment: 12 page

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

A CONVEXITY THEOREM FOR SEMISIMPLE SYMMETRIC SPACES

We generalize Kostant's convexity theorem for the Iwasawa decomposition of a real semisimple Lie group G to the following situation. Let T be an involution of G, and H = (G τ)°. Then there exists an Iwasawa decomposition G = KA N with certain compatibility properties, e.g