831 research outputs found
Reported shoes size during GH therapy: is foot overgrowth a myth or reality?
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Achkar B
- Adachi S
- Adam L
- Adamczyk L
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- Adelman J
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- Zemaityte G
- Zeng JC
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- Zhemchugov A
- Zheng Z
- Zhong D
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- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
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- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Performance of the CMS Cathode Strip Chambers with Cosmic Rays
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2009
- Field of study
The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device
in the CMS endcaps. Their performance has been evaluated using data taken
during a cosmic ray run in fall 2008. Measured noise levels are low, with the
number of noisy channels well below 1%. Coordinate resolution was measured for
all types of chambers, and fall in the range 47 microns to 243 microns. The
efficiencies for local charged track triggers, for hit and for segments
reconstruction were measured, and are above 99%. The timing resolution per
layer is approximately 5 ns
miRNAs Expression Analysis in Paired Fresh/Frozen and Dissected Formalin Fixed and Paraffin Embedded Glioblastoma Using Real-Time PCR
- Author
- Agati R
- Albani F
- Amadori A
- Ambrosetto G
- Api P
- Ariatti A
- Artioli F
- Bacci A
- Baldin E
- Baldrati A
- Barbieri E
- Bartolini S
- Baruzzi A
- Bellavista E
- Bernardini I
- Bertolini F
- Biasini C
- Bigliardi G
- Bisulli F
- Bonora E
- Brandes A
- Bunkheila F
- Calbucci F
- Carelli V
- Carpeggiani P
- Cartei F
- Casmiro M
- Cavalleri F
- Cavallo M
- Cavallo M
- Cavanna L
- Cenni P
- Cerasoli S
- Cerasti D
- Ceruti S
- Costa M
- Crafa P
- Cremonini Am
- Crisci M
- Crisi G
- Cruciani G
- D'Alessandro R
- Dall'Agata M
- Dall'Occa P
- Dascola I
- Dazzi C
- de Biase D
- de Pasqua S
- Depenni R
- Emiliani E
- Eusebi V
- Faedi M
- Fainardi E
- Fallica E
- Ferro S
- Fiorica F
- Florindo I
- Franceschi C
- Franceschi E
- Frattarelli M
- Frezza G
- Galletti G
- Gamboni A
- Gentili G
- Giombelli E
- Giorgi C
- Giovannini A
- Granieri E
- Grasso V
- Greco G
- Guerzoni R
- Guidetti D
- Guidi Ar
- Guidi C
- Guiducci G
- Iaccarino C
- Immovilli P
- Iorio P
- Latini F
- Lelli G
- Leonardi M
- Marcello N
- Marucci G
- Mazza S
- Meletti Stefano
- Michelucci R
- Monetti C
- Montanari E
- Morandi L
- Morelli N
- Mostacci B
- Mucciarini C
- Neri W
- Nichelli Paolo Frigio
- Nobile C. PERNO Study Group
- Palandri G
- Pasini E
- Pasini G
- Pasquinelli M
- Pasquini E
- Pasquini U
- Pastore Trossello M
- Patuelli A
- Pession A
- Pettorelli E
- Pinna G
- Pisanello A
- Poggi R
- Polselli A
- Ragazzi M
- Ramponi V
- Rasi F
- Ravasio A
- Riguzzi P
- Rinaldi R
- Rizzi R
- Rizzi S
- Romeo G
- Saletti A
- Sasso E
- Schivalocchi R
- Seraceni S
- Servadei F
- Silini Em
- Sintini M
- Spagnolli F
- Strumia S
- Stucchi C
- Taccioli C
- Tamarozzi R
- Testoni S
- Tinuper P
- Tola Mr
- Torelli P
- Tosoni A
- Trocino C
- Urbini B
- Valentini A
- Vanzo C
- Visani M
- Viti B
- Zuccoli G
- Zumaglini F
- Zunarelli E
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
miRNAs are small molecules involved in gene regulation. Each tissue shows a characteristic miRNAs epression profile that could be altered during neoplastic transformation. Glioblastoma is the most aggressive brain tumour of the adult with a high rate of mortality. Recognizing a specific pattern of miRNAs for GBM could provide further boost for target therapy. The availability of fresh tissue for brain specimens is often limited and for this reason the possibility of starting from formalin fixed and paraffin embedded tissue (FFPE) could very helpful even in miRNAs expression analysis. We analysed a panel of 19 miRNAs in 30 paired samples starting both from FFPE and Fresh/Frozen material. Our data revealed that there is a good correlation in results obtained from FFPE in comparison with those obtained analysing miRNAs extracted from Fresh/Frozen specimen. In the few cases with a not good correlation value we noticed that the discrepancy could be due to dissection performed in FFPE samples. To the best of our knowledge this is the first paper demonstrating that the results obtained in miRNAs analysis using Real-Time PCR starting from FFPE specimens of glioblastoma are comparable with those obtained in Fresh/Frozen samples
Pattern of care and effectiveness of treatment for glioblastoma patients in the real world: Results from a prospective population-based registry. Could survival differ in a high-volume center?
- Author
- Agati R
- Albani Fiorenzo
- Albani Francesca
- Amadori A
- Ambrosetto G
- Api P
- Ariatti A
- Artioli F
- Bacci A
- Baldin E
- Baldrati A
- Barbieri E
- Bartolini S
- Bartolini Stefania
- Baruzzi A
- Baruzzi Agostino
- Bellavista Elena
- Bernardini I
- Bertolini F
- Biasini C
- Bigliardi G
- Bisulli F
- Bonora E
- Brandes A
- Brandes Alba A
- Bunkheila F
- Calbucci F
- Carelli V
- Carpeggiani P
- Cartei Gian Franco
- Casmiro M
- Cavalleri F
- Cavallo M
- Cavallo M
- Cavanna L
- Cavanna Luigi
- Cavuto Silvio
- Cenni Paola
- Cerasoli S
- Cerasoli Serenella
- Cerasti D
- Ceruti S
- Costa M
- Crafa P
- Cremonini A. M
- Crisci M
- Crisi G
- Crisi Girolamo
- Cruciani Giovanni
- D&apos
- Dall&apos
- Dall&apos
- Dascola I
- Dazzi C
- Dazzi Claudio
- De Biase D
- De Pasqua S
- Depenni R
- Depenni Roberta
- Di Iorio Paolo
- Emiliani E
- Ermani Mario
- Eusebi V
- Faedi M
- Faedi Marina
- Fainardi Enrico
- Fallica E
- Ferro S
- Fiorica F
- Florindo I
- Franceschi C
- Franceschi E
- Franceschi Enrico
- Frattarelli M
- Frezza G
- Galletti G
- Gamboni A
- Gardini Giorgio
- Gentili G
- Giorgi C
- Giovannini A
- Granieri E
- Grasso V
- Greco G
- Guerzoni R
- Guidetti D
- Guidi Ar
- Guidi Caterina
- Guiducci Gianluca
- Iaccarino C
- Immovilli P
- Lanza Giovanni
- Latini F
- Lelli Anna Giulia
- Leonardi M
- Marcello N
- Marucci G
- Marucci Gianluca
- Mazza S
- Mazzocchi Valeria
- Meletti S
- Michelucci R
- Monetti C
- Montanari E
- Morandi L
- Morandi Luca
- Morelli N
- Mostacci B
- Mucciarini C
- Mucciarini Claudia
- Neri W
- Nichelli P
- Palandri G
- Pasini E
- Pasini G
- Pasini Giuseppe
- Pasquinelli M
- Pasquini E
- Pasquini Umberto
- Pastore Trossello M
- Patuelli A
- Pession A
- Pettorelli E
- Pinna G
- Pisanello A
- Pisanello Anna
- Polselli A
- Ragazzi M
- Ramponi V
- Rasi F
- Ravasio A
- Riguzzi P
- Rinaldi R
- Rizzi Riccardo
- Rizzi S
- Romeo G
- Saletti A
- Sasso E
- Schivalocchi R
- Seraceni S
- Servadei F
- Silini Em
- Silini Enrico Maria
- Sintini M
- Spagnolli F
- Strumia S
- Stucchi C
- Tamarozzi R
- Testoni S
- Tinuper P
- Tola M. R
- Torelli P
- Tosoni A
- Tosoni Alicia
- Trocino C
- Urbini B
- Urbini Benedetta
- Valentini A
- Vanzo C.
- Viti B
- Zuccoli G
- Zumaglini F
- Zunarelli E
- Zunarelli Elena
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2014
- Field of study
BACKGROUND:
As yet, no population-based prospective studies have been conducted to investigate the incidence and clinical outcome of glioblastoma (GBM) or the diffusion and impact of the current standard therapeutic approach in newly diagnosed patients younger than aged 70 years.
METHODS:
Data on all new cases of primary brain tumors observed from January 1, 2009, to December 31, 2010, in adults residing within the Emilia-Romagna region were recorded in a prospective registry in the Project of Emilia Romagna on Neuro-Oncology (PERNO). Based on the data from this registry, a prospective evaluation was made of the treatment efficacy and outcome in GBM patients.
RESULTS:
Two hundred sixty-seven GBM patients (median age, 64 y; range, 29-84 y) were enrolled. The median overall survival (OS) was 10.7 months (95% CI, 9.2-12.4). The 139 patients 64aged 70 years who were given standard temozolomide treatment concomitant with and adjuvant to radiotherapy had a median OS of 16.4 months (95% CI, 14.0-18.5). With multivariate analysis, OS correlated significantly with KPS (HR = 0.458; 95% CI, 0.248-0.847; P = .0127), MGMT methylation status (HR = 0.612; 95% CI, 0.388-0.966; P = .0350), and treatment received in a high versus low-volume center (HR = 0.56; 95% CI, 0.328-0.986; P = .0446).
CONCLUSIONS:
The median OS following standard temozolomide treatment concurrent with and adjuvant to radiotherapy given to (72.8% of) patients aged 6470 years is consistent with findings reported from randomized phase III trials. The volume and expertise of the treatment center should be further investigated as a prognostic factor
Combined measurement of differential and total cross sections in the H → γγ and the H → ZZ* → 4ℓ decay channels at s=13 TeV with the ATLAS detector
- Author
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- Álvarez Piqueras D
- Åkesson TPA
- Šfiligoj T
- Ženiš T
- Živković L
- Publication venue
- Elsevier
- Publication date
- 01/01/2018
- Field of study
A combined measurement of differential and inclusive total cross sections of Higgs boson production is performed using 36.1 fb−1 of 13 TeV proton–proton collision data produced by the LHC and recorded by the ATLAS detector in 2015 and 2016. Cross sections are obtained from measured H→γγ and H→ZZ*(→4ℓ event yields, which are combined taking into account detector efficiencies, resolution, acceptances and branching fractions. The total Higgs boson production cross section is measured to be 57.0−5.9 +6.0 (stat.) −3.3 +4.0 (syst.) pb, in agreement with the Standard Model prediction. Differential cross-section measurements are presented for the Higgs boson transverse momentum distribution, Higgs boson rapidity, number of jets produced together with the Higgs boson, and the transverse momentum of the leading jet. The results from the two decay channels are found to be compatible, and their combination agrees with the Standard Model predictions
Measurement of VH, H → b b ¯ production as a function of the vector-boson transverse momentum in 13 TeV pp collisions with the ATLAS detector
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- Aad G
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- Abdinov O
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- Chelkov GA
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- Zhang Z
- Zhao P
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- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
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- Zhou MS
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- Zhu CG
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- Zhu HL
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- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Cross-sections of associated production of a Higgs boson decaying into bottom-quark pairs and an electroweak gauge boson, W or Z, decaying into leptons are measured as a function of the gauge boson transverse momentum. The measurements are performed in kinematic fiducial volumes defined in the `simplified template cross-section' framework. The results are obtained using 79.8 fb-1 of proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13 TeV. All measurements are found to be in agreement with the Standard Model predictions, and limits are set on the parameters of an effective Lagrangian sensitive to modifications of the Higgs boson couplings to the electroweak gauge bosons
Search for High-Mass Resonances Decaying to τν in pp Collisions at √s=13 TeV with the ATLAS Detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Adachi S
- Adamczyk L
- Adelman J
- Adersberger M
- Adye T
- Affolder AA
- Afik Y
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahlen SP
- Ahmadov F
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov AV
- Alberghi GL
- Albert J
- Albicocco P
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexander G
- Alexopoulos T
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
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- Zorbas TG
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- Zu Theenhausen H Meyer
- zur Nedden M
- Zwalinski L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2018
- Field of study
A search for high-mass resonances decaying to τν using proton-proton collisions at √s=13 TeV produced by the Large Hadron Collider is presented. Only τ-lepton decays with hadrons in the final state are considered. The data were recorded with the ATLAS detector and correspond to an integrated luminosity of 36.1 fb−1. No statistically significant excess above the standard model expectation is observed; model-independent upper limits are set on the visible τν production cross section. Heavy W′ bosons with masses less than 3.7 TeV in the sequential standard model and masses less than 2.2–3.8 TeV depending on the coupling in the nonuniversal G(221) model are excluded at the 95% credibility level
Measurement of the t¯tZ and t¯tW cross sections in proton-proton collisions at √s=13 TeV with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abbott DC
- Abdinov O
- Abeloos B
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
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- Abulaiti Y
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- Zhemchugov A
- Zheng Z
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- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
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- Zwalinski L
- Álvarez Piqueras D
- Åkesson TPA
- Šfiligoj T
- Ženiš T
- Živković L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2019
- Field of study
A measurement of the associated production of a top-quark pair (t¯t) with a vector boson (W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV is presented, using 36.1 fb−1 of integrated luminosity collected by the ATLAS detector at the Large Hadron Collider. Events are selected in channels with two same- or opposite-sign leptons (electrons or muons), three leptons or four leptons, and each channel is further divided into multiple regions to maximize the sensitivity of the measurement. The t¯tZ and t¯tW production cross sections are simultaneously measured using a combined fit to all regions. The best-fit values of the production cross sections are σt¯tZ=0.95±0.08stat±0.10syst pb and σt¯tW=0.87±0.13stat±0.14syst pb in agreement with the Standard Model predictions. The measurement of the t¯tZ cross section is used to set constraints on effective field theory operators which modify the t¯tZ vertex
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