Majorana neutrinos and lepton-number-violating signals in top-quark and W-boson rare decays

We discuss rare lepton-number-violating top-quark and W-boson four-body decays to final states containing a same-charge lepton pair, of the same or of different flavors: t -> b W- li^+ lj^+ and W+ -> J J' li^+ lj^+, where i \ne j or i=j and J J' stands for two light jets originating from a (u-bar d) or a (c-bar s) pair. These \Delta L=2 decays are forbidden in the Standard Model and may be mediated by exchanges of Majorana neutrinos. We adopt a model independent approach for the Majorana neutrinos mixing pattern and calculate the branching ratios (BR) for these decays. We find, for example, that for O(1) mixings between heavy and light Majorana neutrinos (not likely but not ruled out) and if at least one of the heavy Majorana neutrinos has a mass of ~100 GeV, then the BR's for these decays are: BR(t -> b li^+ lj^+ W-) ~ 10^{-4} and BR(W+ -> li^+ lj^+ J J') ~ 10^{-7} if m_N ~ 100 GeV and BR(t -> b li^+ lj^+ J J') ~ BR(W+ -> li^+ lj^+ J J') ~ 0.01 if m_N < 50 GeV. Taking into account the present limits on the neutrino mixing parameters, we obtain more realistic values for these BR's: BR(t -> b li^+ lj^+ W-) ~ 10^{-6} and BR(W+ -> li^+ lj^+ J J') ~ 10^{-10} for m_N ~ 100 GeV and BR(t -> b li^+ lj^+ J J') ~ BR(W+ -> li^+ lj^+ J J') ~ 10^{-6} for m_N < 50 GeV.Comment: latex, 7 pages, 2 figures. V2 as published in PL

Heavy Majorana Neutrinos in the Effective Lagrangian Description: Application to Hadron Colliders

We consider the effects of heavy Majorana neutrinos N with sub-TeV masses. We argue that the mere presence of these particles would be a signal of physics beyond the minimal seesaw mechanism and their interactions are, therefore, best described using an effective Lagrangian. We then consider the complete set of leading effective operators (up to dimension 6) involving the N and Standard Model fields and show that these interactions can be relatively easy to track at high-energy colliders. For example, we find that an exchange of a TeV-scale heavy vector field can yield thousands of characteristic same-sign lepton number violating l^+ l^+ j j events (j=light jet) at the LHC if m_N < 600 GeV, which can also have a distinctive forward-backward asymmetry signal; even the Tevatron has good prospects for this signature if m_N < 300 GeV.Comment: 4 pages, 1 figur

The roles of immune cells in bone healing; what we know, do not know and future perspectives

Key events occurring during the bone healing include well-orchestrated and complex interactions between immune cells, multipotential stromal cells (MSCs), osteoblasts and osteoclasts. Through three overlapping phases of this physiological process, innate and adaptive immune cells, cytokines and chemokines have a significant role to play. The aim of the escalating immune response is to achieve an osseous healing in the shortest time and with the least complications facilitating the restoration of function. The uninterrupted progression of these biological events in conjunction with a favourable mechanical environment (stable fracture fixation) remains the hallmark of successful fracture healing. When failure occurs, either the biological environment or the mechanical one could have been disrupted. Not infrequently both may be compromised. Consequently, regenerative treatments involving the use of bone autograft, allograft or synthetic matrices supplemented with MSCs are increasingly used. A better understanding of the bone biology and osteoimmunology can help to improve these evolving cell-therapy based strategies. Herein, an up to date status of the role of immune cells during the different phases of bone healing is presented. Additionally, the known and yet to know events about immune cell interactions with MSCs and osteoblasts and osteoclasts and the therapeutic implications are being discussed

Multi-messenger observations of a binary neutron star merger

On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta