Overview and Operation of U.S. Financial Sanctions, Including the Example of Iran

Financial sanctions are increasingly being used in the mix of international economic sanctions being employed by the United Nations, regional entities, and individual countries, including the United States. These financial sanctions have become more focused and effective as the tools and techniques have improved significantly for tracing and identifying the financial transactions of terrorists, weapons proliferators, human rights violators, drug cartels, and others. These sanctions can not only freeze financial assets and prohibit or limit financial transactions, but they also impede trade by making it difficult to pay for the export or import of goods and services. In spite of this growing impact of financial sanctions, these sanctions are not well understood outside of a small group of experts. This article provides an introduction to the mechanics and operation of U.S. financial sanctions, and it illustrates their use against Iran

Intramolecular Energy and Electron Transfer Within a Diazaperopyrenium-Based Cyclophane

Molecules capable of performing highly efficient energy transfer and ultrafast photo-induced electron transfer in well-defined multichromophoric structures are indispensable to the development of artificial photosynthetic systems. Herein, we report on the synthesis, characterization and photophysical properties of a rationally designed multichromophoric tetracationic cyclophane, DAPPBox^(4+), containing a diazaperopyrenium (DAPP^(2+)) unit and an extended viologen (ExBIPY^(2+)) unit, which are linked together by two p-xylylene bridges. Both ^1H NMR spectroscopy and single crystal X-ray diffraction analysis confirm the formation of an asymmetric, rigid, box-like cyclophane, DAPPBox^(4+). The solid-state superstructure of this cyclophane reveals a herringbone-type packing motif, leading to two types of π···π interactions: (i) between the ExBIPY^(2+) unit and the DAPP^(2+) unit (π···π distance of 3.7 Å) in the adjacent parallel cyclophane, as well as (ii) between the ExBIPY^(2+) unit (π···π distance of 3.2 Å) and phenylene ring in the closest orthogonal cyclophane. Moreover, the solution-phase photophysical properties of this cyclophane have been investigated by both steady-state and time-resolved absorption and emission spectroscopies. Upon photoexcitation of DAPPBox^(4+) at 330 nm, rapid and quantitative intramolecular energy transfer occurs from the ^1*ExBIPY^(2+) unit to the DAPP^(2+) unit in 0.5 ps to yield ^1*DAPP^(2+). The same excitation wavelength simultaneously populates a higher excited state of ^1*DAPP^(2+) which then undergoes ultrafast intramolecular electron transfer from ^1*DAPP^(2+) to ExBIPY^(2+) to yield the DAPP^(3+•) – ExBIPY^(+•) radical ion pair in τ = 1.5 ps. Selective excitation of DAPP^(2+) at 505 nm populates a lower excited state where electron transfer is kinetically unfavorable

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

Overview and Operation of U.S. Financial Sanctions, Including the Example of Iran

Financial sanctions are increasingly being used in the mix of international economic sanctions being employed by the United Nations, regional entities, and individual countries, including the United States. These financial sanctions have become more focused and effective as the tools and techniques have improved significantly for tracing and identifying the financial transactions of terrorists, weapons proliferators, human rights violators, drug cartels, and others. These sanctions can not only freeze financial assets and prohibit or limit financial transactions, but they also impede trade by making it difficult to pay for the export or import of goods and services. In spite of this growing impact of financial sanctions, these sanctions are not well understood outside of a small group of experts. This article provides an introduction to the mechanics and operation of U.S. financial sanctions, and it illustrates their use against Iran

Catalytic Solvolytic and Hydrolytic Degradation of Toxic Methyl Paraoxon with La(catecholate)-Functionalized Porous Organic Polymers

Two robust catechol-functionalized porous organic polymers (catPOPs) with different <i>T</i>_d-directing nodes were synthesized using a cobalt-catalyzed acetylene trimerization (CCAT) strategy. Postsynthesis metallation was readily carried out with La­(acac)₃ to afford catalytically active La-functionalized catPOPs for the solvolytic and hydrolytic degradation of the toxic organophosphate compound methyl paraoxon, a simulant for nerve agents

Enhanced Catalytic Activity through the Tuning of Micropore Environment and Supercritical CO₂ Processing: Al(Porphyrin)-Based Porous Organic Polymers for the Degradation of a Nerve Agent Simulant

An Al­(porphyrin) functionalized with a large axial ligand was incorporated into a porous organic polymer (POP) using a cobalt-catalyzed acetylene trimerization strategy. Removal of the axial ligand afforded a microporous POP that is catalytically active in the methanolysis of a nerve agent simulant. Supercritical CO₂ processing of the POP dramatically increased the pore size and volume, allowing for significantly higher catalytic activities