621 research outputs found
A numerical algorithm for endochronic plasticity and comparison with experiment
A numerical algorithm based on the finite element method of analysis of the boundary value problem in a continuum is presented, in the case where the plastic response of the material is given in the context of endochronic plasticity. The relevant constitutive equation is expressed in incremental form and plastic effects are accounted for by the method of an induced pseudo-force in the matrix equations. The results of the analysis are compared with observed values in the case of a plate with two symmetric notches and loaded longitudinally in its own plane. The agreement between theory and experiment is excellent
On the Application of Deformation Kinetics to Nonlinear Constitutive Relations at Higher Temperatures
A single phenomenological constitutive equation is derived theoretically from first principles and applied to aluminum, tin and lead. The theory is based on deformation kinetics of steady creep in which the fundamental mechanism is atomic transport over potential barriers whose conformation is distorted by the application of a stress field. The form of the functional dependence of barrier distortion and stress over the entire temperature range is found to be a sigmoidal curve which tends to straight lines of a unit slope in the small and high stress regions. With this form of barrier distortion, the constitutive equation prediction the steady creep behavior of aluminum, tin and lead over a wide range of temperature and stress
Some Recent Developments in the Endochronic Theory with Application to Cyclic Histories
Constitutive equations with only two easily determined material constants predict the stress (strain) response of normalized mild steel to a variety of general strain (stress) histories, without a need for special unloading-reloading rules. The equations are derived from the endochronic theory of plasticity of isotropic materials with an intrinsic time scale defined in the plastic strain space. Agreement between theoretical predictions and experiments are are excellent quantitatively in cases of various uniaxial constant amplitude histories, variable uniaxial strain amplitude histories and cyclic relaxation. The cyclic ratcheting phenomenon is predicted by the present theory
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Strategies for recruitment to a population-based lung cancer prevention trial: The CARET experience with heavy smokers
Peristaltic Transport of a Couple Stress Fluid: Some Applications to Hemodynamics
The present paper deals with a theoretical investigation of the peristaltic
transport of a couple stress fluid in a porous channel. The study is motivated
towards the physiological flow of blood in the micro-circulatory system, by
taking account of the particle size effect. The velocity, pressure gradient,
stream function and frictional force of blood are investigated, when the
Reynolds number is small and the wavelength is large, by using appropriate
analytical and numerical methods. Effects of different physical parameters
reflecting porosity, Darcy number, couple stress parameter as well as amplitude
ratio on velocity profiles, pumping action and frictional force, streamlines
pattern and trapping of blood are studied with particular emphasis. The
computational results are presented in graphical form. The results are found to
be in good agreement with those of Shapiro et. al \cite{r25} that was carried
out for a non-porous channel in the absence of couple stress effect. The
present study puts forward an important observation that for peristaltic
transport of a couple stress fluid during free pumping when the couple stress
effect of the fluid/Darcy permeability of the medium, flow reversal can be
controlled to a considerable extent. Also by reducing the permeability it is
possible to avoid the occurrence of trapping phenomenon
Materials - Man\u27s Essential Link with the Future
(An invited address delivered on the occasion of the commemoration of the 100th anniversary of the Iowa Academy of Science.)
Materials are essential for the support of human life. At the primitive level they provide food, shelter and protection against the natural elements. At the advanced level of the technological civilization of the 20th century they support the luxuries to which we have become accustomed-and which we insist upon calling our needs. Today they are essential to our industry, our economy and our national security
Interventions for promoting smoking cessation during pregnancy
Original article can be found at: http://www3.interscience.wiley.com This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2004, Issue 4. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic Reviews should be consulted for the most recent version of the Review.’ Lumley, J. , Oliver, S.S. , Chamberlain, C. and Oakley, L. 'Interventions for promoting smoking cessation during pregnancy.' Cochrane Database of Systematic Reviews 2004 (4) CD001055 DOI: 10.1002/14651858.CD001055.pub2Background: Tobacco smoking in pregnancy remains one of the few preventable factors associated with complications in pregnancy, low birthweight, preterm birth and has serious long-term health implications for women and babies. Smoking in pregnancy is decreasing in high-income countries and increasing in low- to middle-income countries and is strongly associated with poverty, low educational attainment, poor social support and psychological illness. Objectives: To assess the effects of smoking cessation interventions during pregnancy on smoking behaviour and perinatal health outcomes. Search strategy: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (June 2008), the Cochrane Tobacco Addiction Group's Trials Register (June 2008), EMBASE, PsycLIT, and CINAHL (all from January 2003 to June 2008). We contacted trial authors to locate additional unpublished data. Selection criteria: Randomised controlled trials where smoking cessation during pregnancy was a primary aim of the intervention. Data collection and analysis: Trials were identified and data extracted by one person and checked by a second. Subgroup analysis was conducted to assess the effect of risk of trial bias, intensity of the intervention and main intervention strategy used. Main results: Seventy-two trials are included. Fifty-six randomised controlled trials (over 20,000 pregnant women) and nine cluster-randomised trials (over 5000 pregnant women) provided data on smoking cessation outcomes. There was a significant reduction in smoking in late pregnancy following interventions (risk ratio (RR) 0.94, 95% confidence interval (CI) 0.93 to 0.96), an absolute difference of six in 100 women who stopped smoking during pregnancy. However, there is significant heterogeneity in the combined data (I2 > 60%). In the trials with the lowest risk of bias, the interventions had less effect (RR 0.97, 95% CI 0.94 to 0.99), and lower heterogeneity (I2 = 36%). Eight trials of smoking relapse prevention (over 1000 women) showed no statistically significant reduction in relapse. Smoking cessation interventions reduced low birthweight (RR 0.83, 95% CI 0.73 to 0.95) and preterm birth (RR 0.86, 95% CI 0.74 to 0.98), and there was a 53.91g (95% CI 10.44 g to 95.38 g) increase in mean birthweight. There were no statistically significant differences in neonatal intensive care unit admissions, very low birthweight, stillbirths, perinatal or neonatal mortality but these analyses had very limited power. Authors' conclusions: Smoking cessation interventions in pregnancy reduce the proportion of women who continue to smoke in late pregnancy, and reduce low birthweight and preterm birth. Smoking cessation interventions in pregnancy need to be implemented in all maternity care settings. Given the difficulty many pregnant women addicted to tobacco have quitting during pregnancy, population-based measures to reduce smoking and social inequalities should be supported.Peer reviewe
Application of the orthogonality principle to the endochronic and Mroz models of plasticity
A new description of the endochronic and the Mroz model is discussed. It is
based on the definition of a suitable pseudo-potential and the use of the
generalized normality assumption. The key-point of this formulation is the
dependence of the pseudo-potentials on state variables
Pseudo-potentials and loading surfaces for an endochronic plasticity theory with isotropic damage
The endochronic theory, developed in the early 70s, allows the plastic
behavior of materials to be represented by introducing the notion of intrinsic
time. With different viewpoints, several authors discussed the relationship
between this theory and the classical theory of plasticity. Two major
differences are the presence of plastic strains during unloading phases and the
absence of an elastic domain. Later, the endochronic plasticity theory was
modified in order to introduce the effect of damage. In the present paper, a
basic endochronic model with isotropic damage is formulated starting from the
postulate of strain equivalence. Unlike the previous similar analyses, in this
presentation the formal tools chosen to formulate the model are those of convex
analysis, often used in classical plasticity: namely pseudopotentials,
indicator functions, subdifferentials, etc. As a result, the notion of loading
surface for an endochronic model of plasticity with damage is investigated and
an insightful comparison with classical models is made possible. A damage
pseudopotential definition allowing a very general damage evolution is given
Psychosocial interventions for supporting women to stop smoking in pregnancy
Background: Tobacco smoking remains one of the few preventable factors associated with complications in pregnancy, and has serious long-term implications for women and babies. Smoking in pregnancy is decreasing in high-income countries, but is strongly associated with poverty and is increasing in low- to middle-income countries.
Objectives: To assess the effects of smoking cessation interventions during pregnancy on smoking behaviour and perinatal health outcomes.
Search methods: In this sixth update, we searched the Cochrane Pregnancy and Childbirth Group's Trials Register (13 November 2015), checked reference lists of retrieved studies and contacted trial authors.
Selection criteria: Randomised controlled trials, cluster-randomised trials, and quasi-randomised controlled trials of psychosocial smoking cessation interventions during pregnancy.
Data collection and analysis: Two review authors independently assessed trials for inclusion and trial quality, and extracted data. Direct comparisons were conducted in RevMan, with meta-regression conducted in STATA 14.
Main results: The overall quality of evidence was moderate to high, with reductions in confidence due to imprecision and heterogeneity for some outcomes. One hundred and two trials with 120 intervention arms (studies) were included, with 88 trials (involving over 28,000 women) providing data on smoking abstinence in late pregnancy. Interventions were categorised as counselling, health education, feedback, incentives, social support, exercise and dissemination.
In separate comparisons, there is high-quality evidence that counselling increased smoking cessation in late pregnancy compared with usual care (30 studies; average risk ratio (RR) 1.44, 95% confidence interval (CI) 1.19 to 1.73) and less intensive interventions (18 studies; average RR 1.25, 95% CI 1.07 to 1.47). There was uncertainty whether counselling increased the chance of smoking cessation when provided as one component of a broader maternal health intervention or comparing one type of counselling with another. In studies comparing counselling and usual care (largest comparison), it was unclear whether interventions prevented smoking relapse among women who had stopped smoking spontaneously in early pregnancy. However, a clear effect was seen in smoking abstinence at zero to five months postpartum (11 studies; average RR 1.59, 95% CI 1.26 to 2.01) and 12 to 17 months (two studies, average RR 2.20, 95% CI 1.23 to 3.96), with a borderline effect at six to 11 months (six studies; average RR 1.33, 95% CI 1.00 to 1.77). In other comparisons, the effect was unclear for most secondary outcomes, but sample sizes were small.
Evidence suggests a borderline effect of health education compared with usual care (five studies; average RR 1.59, 95% CI 0.99 to 2.55), but the quality was downgraded to moderate as the effect was unclear when compared with less intensive interventions (four studies; average RR 1.20, 95% CI 0.85 to 1.70), alternative interventions (one study; RR 1.88, 95% CI 0.19 to 18.60), or when smoking cessation health education was provided as one component of a broader maternal health intervention.
There was evidence feedback increased smoking cessation when compared with usual care and provided in conjunction with other strategies, such as counselling (average RR 4.39, 95% CI 1.89 to 10.21), but the confidence in the quality of evidence was downgraded to moderate as this was based on only two studies and the effect was uncertain when feedback was compared to less intensive interventions (three studies; average RR 1.29, 95% CI 0.75 to 2.20).
High-quality evidence suggests incentive-based interventions are effective when compared with an alternative (non-contingent incentive) intervention (four studies; RR 2.36, 95% CI 1.36 to 4.09). However pooled effects were not calculable for comparisons with usual care or less intensive interventions (substantial heterogeneity, I2 = 93%).
High-quality evidence suggests the effect is unclear in social support interventions provided by peers (six studies; average RR 1.42, 95% CI 0.98 to 2.07), in a single trial of support provided by partners, or when social support for smoking cessation was provided as part of a broader intervention to improve maternal health.
The effect was unclear in single interventions of exercise compared to usual care (RR 1.20, 95% CI 0.72 to 2.01) and dissemination of counselling (RR 1.63, 95% CI 0.62 to 4.32).
Importantly, high-quality evidence from pooled results demonstrated that women who received psychosocial interventions had a 17% reduction in infants born with low birthweight, a significantly higher mean birthweight (mean difference (MD) 55.60 g, 95% CI 29.82 to 81.38 g higher) and a 22% reduction in neonatal intensive care admissions. However the difference in preterm births and stillbirths was unclear. There did not appear to be adverse psychological effects from the interventions.
The intensity of support women received in both the intervention and comparison groups has increased over time, with higher-intensity interventions more likely to have higher-intensity comparisons, potentially explaining why no clear differences were seen with increasing intervention intensity in meta-regression analyses. Among meta-regression analyses: studies classified as having 'unclear' implementation and unequal baseline characteristics were less effective than other studies. There was no clear difference between trials implemented by researchers (efficacy studies), and those implemented by routine pregnancy staff (effectiveness studies), however there was uncertainty in the effectiveness of counselling in four dissemination trials where the focus on the intervention was at an organisational level. The pooled effects were similar in interventions provided for women classified as having predominantly low socio-economic status, compared to other women. The effect was significant in interventions among women from ethnic minority groups; however not among indigenous women. There were similar effect sizes in trials with biochemically validated smoking abstinence and those with self-reported abstinence. It was unclear whether incorporating use of self-help manuals or telephone support increased the effectiveness of interventions.
Authors' conclusions: Psychosocial interventions to support women to stop smoking in pregnancy can increase the proportion of women who stop smoking in late pregnancy and the proportion of infants born low birthweight. Counselling, feedback and incentives appear to be effective, however the characteristics and context of the interventions should be carefully considered. The effect of health education and social support is less clear. New trials have been published during the preparation of this review and will be included in the next update
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