Nuevas citas de plantas acuáticas para la Laguna Redonda (Málaga), recientemente restaurada

La Laguna Redonda es una de las ocho lagunas pertenecientes al complejo lacustre “Lagunas de Campillos” situado en las Zonas externas de la Subbética. Esta laguna fue objeto de fuertes alteraciones antrópicas en las décadas de los años 70 y 80, al ser utilizada con cierta asiduidad para el depósito de escombros. La ocupación de la mayor parte del vaso lacustre por estos materiales, junto con las alteraciones de las escorrentías superficiales que alimentan la laguna ocasionó un comportamiento hídrico propio de un humedal temporal ocasional (Carrasco et al. 2005). Todas estas perturbaciones debieron tener repercusiones negativas en las comunidades acuáticas de la misma. A principios de otoño de 2008 dentro del proyecto “Corrección de riberas y zonas húmedas en la provincia de Málaga”, llevado a cabo por parte de la Consejería de Medio Ambiente de la Junta de Andalucía, se procedió a una serie de actuaciones en el vaso lagunar

Determinación de diferentes escalas de riesgo cardiovascular en el profesorado español: variables asociadas

Artículos originales[EN] Introduction: Cardiovascular disease is currently one of the most prevalent non-communicable diseases, affecting nearly 57% of the world’s population, accounting for 32% of deaths worldwide. The aim of the study is to determine the cardiovascular risk of teaching staff. Methods: Retrospective, cross-sectional study carried out on 4,738 teachers from different Spanish geographical areas with a mean age of 41 years. Different variables related to cardiovascular risk are determined, such as overweight and obesity scales, nonalcoholic fatty liver scales, atherogenic indices, metabolic syndrome and cardiovascular risk scales, among others. Results: Among the results we highlight a prevalence of hypercholesterolemia of 41%, hyperteriglyceridemia 12.1%, hypertension 15.5%, obesity using BMI 13%, high risk of fatty liver 11.3% and moderate or high SCORE values 11.4%. Conclusion: The teaching staff is not free from developing CVD that we can relate to the lack of physical activity and an unhealthy diet that increases the prevalence of obesity and overweight. [ES] Introducción: Las enfermedades cardiovasculares son actualmente una de las enfermedades no transmisibles más prevalentes, ya que afectan a casi el 57% de la población mundial siendo responsables del 32% de las muertes en el mundo. El objetivo del estudio es conocer el riesgo cardiovascular del personal docente. Métodos: Estudio retrospectivo y transversal realizado en 4.738 profesores de diferentes zonas geográficas españo las con una edad media de 41 años. Se determinan diferentes variables relacionadas con el riesgo cardiovascular, como escalas de sobrepeso y obesidad, escalas de hígado graso no alcohólico, índices aterogénicos, síndrome me tabólico y escalas de riesgo cardiovascular, entre otras. Resultados: Entre los resultados destacamos una prevalencia de hipercolesterolemia del 41%, hiperterigliceri demia del 12,1%, hipertensión del 15,5%, obesidad mediante IMC del 13%, alto riesgo de hígado graso del 11,3% y valores de SCORE moderados o altos del 11,4%. Conclusión: El profesorado no está exento de desarrollar ECV que podemos relacionar con la falta de actividad física y una dieta poco saludable que aumenta la prevalencia de obesidad y sobrepeso.N

Two multi-fragment recombination events resulted in the beta-lactam-resistant serotype 11A-ST6521 related to Spain9V-ST156 pneumococcal clone spreading in south-western Europe, 2008 to 2016

Background: The successful pneumococcal clone Spain(9V)-ST156 (PMEN3) is usually associated with vaccine serotypes 9V and 14. Aim: Our objective was to analyse the increase of a serotype 11A variant of PMEN3 as cause of invasive pneumococcal disease (IPD) in Spain and its spread in south-western Europe. Methods: We conducted a prospective multicentre study of adult IPD in Spain (2008-16). Furthermore, a subset of 61 penicillin-resistant serotype 11A isolates from France, Italy, Portugal and Spain were subjected to whole genome sequencing (WGS) and compared with 238 genomes from the European Nucleotide Archive (ENA). Results: Although the incidence of serotype 11A in IPD was stable, a clonal shift was detected from CC62 (penicillin-susceptible) to CC156 (penicillin-resistant). By WGS, three major 11A-CC156 lineages were identified, linked to ST156 (n=5 isolates; France, Italy and Portugal), ST166 (n=4 isolates; France and Portugal) and ST838/6521 (n=52 isolates; France, Portugal and Spain). Acquisition of the capsule allowed to escape vaccine effect. AP200 (11A-ST62) was the donor for ST156 and ST838/6521 but not for ST166. In-depth analysis of ST838/6521 lineage showed two multi-fragment recombination events including four and seven fragments from an 11A-ST62 and an NT-ST344 representative, respectively. Conclusion: The increase in penicillin-resistant serotype 11A IPD in Spain was linked to the spread of a vaccine escape PMEN3 recombinant clone. Several recombination events were observed in PMEN3 acquiring an 11A capsule. The most successful 11A-PMEN3 lineage spreading in south-western Europe appeared after two multi-fragment recombination events with representatives of two major pneumococcal clones (11A-ST62 and NT-ST344)

Surface indicators are correlated with soil multifunctionality in global drylands

1. Multiple ecosystem functions need to be considered simultaneously to manage and protect the several ecosystem services that are essential to people and their environments. Despite this, cost effective, tangible, relatively simple and globally relevant methodologies to monitor in situ soil multifunctionality, that is, the provision of multiple ecosystem functions by soils, have not been tested at the global scale. 2. We combined correlation analysis and structural equation modelling to explore whether we could find easily measured, field‐based indicators of soil multifunctionality (measured using functions linked to the cycling and storage of soil carbon, nitrogen and phosphorus). To do this, we gathered soil data from 120 dryland ecosystems from five continents. 3. Two soil surface attributes measured in situ (litter incorporation and surface aggregate stability) were the most strongly associated with soil multifunctionality, even after accounting for geographic location and other drivers such as climate, woody cover, soil pH and soil electric conductivity. The positive relationships between surface stability and litter incorporation on soil multifunctionality were greater beneath the canopy of perennial vegetation than in adjacent, open areas devoid of vascular plants. The positive associations between surface aggregate stability and soil functions increased with increasing mean annual temperature. 4. Synthesis and applications. Our findings demonstrate that a reduced suite of easily measured in situ soil surface attributes can be used as potential indicators of soil multifunctionality in drylands world‐wide. These attributes, which relate to plant litter (origin, incorporation, cover), and surface stability, are relatively cheap and easy to assess with minimal training, allowing operators to sample many sites across widely varying climatic areas and soil types. The correlations of these variables are comparable to the influence of climate or soil, and would allow cost‐effective monitoring of soil multifunctionality under changing land‐use and environmental conditions. This would provide important information for evaluating the ecological impacts of land degradation, desertification and climate change in drylands world‐wide.This work was funded by the European Research Council ERC Grant agreement 242658 (BIOCOM). CYTED funded networking activities (EPES, Acción 407AC0323). D.J.E. acknowledges support from the Australian Research Council (DP150104199) and F.T.M. support from the European Research Council (BIODESERT project, ERC Grant agreement no 647038), from the Spanish Ministerio de Economía y Competitividad (BIOMOD project, ref. CGL2013-44661-R) and from a Humboldt Research Award from the Alexander von Humboldt Foundation. M.D.-B. was supported by REA grant agreement no 702057 from the Marie Sklodowska-Curie Actions of the Horizon 2020 Framework Programme H2020-MSCA-IF-2016), J.R.G. acknowledges support from CONICYT/FONDECYT no 1160026

Analysis of the common genetic component of large-vessel vasculitides through a meta- Immunochip strategy

Giant cell arteritis (GCA) and Takayasu's arteritis (TAK) are major forms of large-vessel vasculitis (LVV) that share clinical features. To evaluate their genetic similarities, we analysed Immunochip genotyping data from 1,434 LVV patients and 3,814 unaffected controls. Genetic pleiotropy was also estimated. The HLA region harboured the main disease-specific associations. GCA was mostly associated with class II genes (HLA-DRB1/HLA-DQA1) whereas TAK was mostly associated with class I genes (HLA-B/MICA). Both the statistical significance and effect size of the HLA signals were considerably reduced in the cross-disease meta-analysis in comparison with the analysis of GCA and TAK separately. Consequently, no significant genetic correlation between these two diseases was observed when HLA variants were tested. Outside the HLA region, only one polymorphism located nearby the IL12B gene surpassed the study-wide significance threshold in the meta-analysis of the discovery datasets (rs755374, P?=?7.54E-07; ORGCA?=?1.19, ORTAK?=?1.50). This marker was confirmed as novel GCA risk factor using four additional cohorts (PGCA?=?5.52E-04, ORGCA?=?1.16). Taken together, our results provide evidence of strong genetic differences between GCA and TAK in the HLA. Outside this region, common susceptibility factors were suggested, especially within the IL12B locus

GEODIVULGAR: Geología y Sociedad

Fac. de Ciencias GeológicasFALSEsubmitte

Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies

Interleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of intensive research because of its crucial role in the pathogenesis of different diseases across many medical specialties. In this context, the present review in which a panel of 13 experts in immunology, dermatology, rheumatology, neurology, hematology, infectious diseases, hepatology, cardiology, ophthalmology and oncology have been involved, puts in common the mechanisms through which IL-17 is considered a molecular target for the development of novel biological therapies in these different fields. A comprehensive review of the literature and analysis of the most outstanding evidence have provided the basis for discussing the most relevant data related to IL-17A blocking agents for the treatment of different disorders, such as psoriasis, psoriatic arthritis, rheumatoid arthritis, ankylosing spondylitis, cardiovascular disorders, non alcoholic fatty liver disease, multiple sclerosis, inflammatory bowel disease, uveitis, hematological and solid cancer. Current controversies are presented giving an opening line for future research.This work was supported by Novartis Pharmaceuticals Spain

Global data on earthworm abundance, biomass, diversity and corresponding environmental properties

Publisher Copyright: © 2021, The Author(s).Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ecological groups. This global dataset contains 10,840 sites, with 184 species, from 60 countries and all continents except Antarctica. The data were obtained from 182 published articles, published between 1973 and 2017, and 17 unpublished datasets. Amalgamating data into a single global database will assist researchers in investigating and answering a wide variety of pressing questions, for example, jointly assessing aboveground and belowground biodiversity distributions and drivers of biodiversity change.Peer reviewe