A writer identification and verification system using HMM based recognizers

In this paper, an off-line, text independent system for writer identification and verification of handwritten text lines using Hidden Markov Model (HMM) based recognizers is presented. For each writer, an individual recognizer is built and trained on text lines of that writer. This results in a number of recognizers, each of which is an expert on the handwriting of exactly one writer. In the identification and verification phase, a text line of unknown origin is presented to each of these recognizers and each one returns a transcription that includes the log-likelihood score for the generated output. These scores are sorted and the resulting ranking is used for both identification and verification. Several confidence measures are defined on this ranking. The proposed writer identification and verification system is evaluated using different experimental setup

Educational Expansion and Interest in Politics in Temporal and Cross-cultural Perspective: A Comparison of West Germany and Switzerland

Interest in politics is a prerequisite for political participation and political engagement. The promotion of political engagement and the education of citizens to become politically mature were basic concerns of educational reforms in the 1960s. This article examines whether educational expansion since then has had an impact on citizens' political interest. The effects of education, age, period, and cohort on political interest are analysed simultaneously. A cross-cultural perspective is included by comparing these effects in Switzerland, a direct democracy that provides its people with extensive opportunities to participate, and West Germany, a representative democracy with less such opportunities. The data base consists of cumulated data sets (ALLBUS, UNIVOX). Results show that there is a robust effect of education: the more educated are more politically interested. The younger generation is not, as is often suggested, more distant from politics. Taking into account their higher educational level, these younger cohorts show the same level of political interest as the older cohorts did at the same ag

T cells in the skin: lymphoma and inflammatory skin disease.

T cells are established contributors to the pathogenesis of atopic dermatitis (AD) and psoriasis, yet whether they are the key drivers or simply unwitting participants remains incompletely understood. Conversely, malignant T cells are the undisputed culprits of cutaneous T cell lymphoma (CTCL), a group of diseases that share key clinical, histopathological and molecular features with inflammatory skin disease (ISD). Here, we compare the pathogenesis of ISD and CTCL and discuss the resulting insights. Recurrent, skin-limited disease implicates skin-resident T cells (TRM) in both ISD and CTCL. In CTCL, malignant T cells recruit benign T cells into inflammatory skin lesions, a disease-amplifying function also proposed for pathogenic T cells in ISD. Mechanistically, cytokines produced by malignant T cells in CTCL and by pathogenic T cells in ISD, respectively, are likely both necessary and sufficient to drive skin inflammation and pruritus, which in turn promotes skin barrier dysfunction and dysbiosis. Therapies for ISD target T cell effector functions but do not address the chronicity of disease while treatments for CTCL target malignant T cells but not primarily the symptoms of the disease. By integrating our understanding of ISD and CTCL, important insights into pathogenesis and therapy can be made which may improve the lives of sufferers of both disease groups

Investigation of the feasibility of FLOX for performance improvement on the S-IC

Feasibility of using liquid fluorine and oxygen /FLOX/ as oxidizer to improve performance of Saturn S-IC stag

Automatic estimation of the readability of handwritten text

Publication in the conference proceedings of EUSIPCO, Lausanne, Switzerland, 200