Human arrival and landscape dynamics in the northern Bahamas

© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Fall, P. L., van Hengstum, P. J., Lavold-Foote, L., Donnelly, J. P., Albury, N. A., & Tamalavage, A. E. Human arrival and landscape dynamics in the northern Bahamas. Proceedings of the National Academy of Sciences of the United States of America, 118(10), (2021): e2015764118, https://doi.org/10.1073/pnas.2015764118.The first Caribbean settlers were Amerindians from South America. Great Abaco and Grand Bahama, the final islands colonized in the northernmost Bahamas, were inhabited by the Lucayans when Europeans arrived. The timing of Lucayan arrival in the northern Bahamas has been uncertain because direct archaeological evidence is limited. We document Lucayan arrival on Great Abaco Island through a detailed record of vegetation, fire, and landscape dynamics based on proxy data from Blackwood Sinkhole. From about 3,000 to 1,000 y ago, forests dominated by hardwoods and palms were resilient to the effects of hurricanes and cooling sea surface temperatures. The arrival of Lucayans by about 830 CE (2σ range: 720 to 920 CE) is demarcated by increased burning and followed by landscape disturbance and a time-transgressive shift from hardwoods and palms to the modern pine forest. Considering that Lucayan settlements in the southern Bahamian archipelago are dated to about 750 CE (2σ range: 600 to 900 CE), these results demonstrate that Lucayans spread rapidly through the archipelago in less than 100 y. Although precontact landscapes would have been influenced by storms and climatic trends, the most pronounced changes follow more directly from landscape burning and ecosystem shifts after Lucayan arrival. The pine forests of Abaco declined substantially between 1500 and 1670 CE, a period of increased regional hurricane activity, coupled with fires on an already human-impacted landscape. Any future intensification of hurricane activity in the tropical North Atlantic Ocean threatens the sustainability of modern pine forests in the northern Bahamas.This research was supported by NSF Awards GSS-1118340 (P.L.F.), OCE-1356509 (P.J.v.H.), OCE-1703087 (P.J.v.H.), and OCE-1356708 (J.P.D.)

The Star Cluster Population of the Collisional Ring Galaxy NGC 922

We present a detailed study of the star cluster population detected in the galaxy NGC922, one of the closest collisional ring galaxies known to date, using HST/WFPC2 UBVI photometry, population synthesis models, and N-body/SPH simulations.We find that 69% of the clusters are younger than 7Myr, and that most of them are located in the ring or along the bar, consistent with the strong Halpha emission. The cluster luminosity function slope of 2.1-2.3 for NGC922 is in agreement with those of young clusters in nearby galaxies. Models of the cluster age distribution match the observations best when cluster disruption is considered. We also find clusters with ages (>50Myr) and masses (>10^5 Msun) that are excellent progenitors for faint fuzzy clusters. The images also show a tidal plume pointing toward the companion. Its stellar age from our analysis is consistent with pre-existing stars that were stripped off during the passage of the companion. Finally, a comparison of the star-forming complexes observed in NGC922 with those of a distant ring galaxy from the GOODS field indicates very similar masses and sizes, suggesting similar origins.Comment: 17 pages including 13 figures. Accepted for publication in AJ. Full resolution version at http://people.physics.tamu.edu/pellerin/Pellerin_etal_NGC922.pd

Stellar Populations and Radial Migrations in Virgo Disk Galaxies

We present stellar age profiles for 64 Virgo cluster disk galaxies whose analysis poses a challenge for current galaxy formation models. Our results can be summarized as follows: first, and contrary to observations of field galaxies, these cluster galaxies are distributed almost equally amongst the three main types of disk galaxy luminosity profiles (I/II/III), indicating that the formation and/or survival of Type II breaks is suppressed within the cluster environment. Second, we find examples of statistically-significant inversions ("U-shapes") in the age profiles of all three disk galaxy types, reminescent of predictions from high-resolution simulations of classically-truncated Type II disks in the field. These features characterize the age profiles for only about a third (<36%) of each disk galaxy type in our sample. An even smaller fraction of cluster disks (~11% of the total sample), exhibit age profiles which decrease outwards (i.e., negative age gradients). Instead, flat and/or positive age gradients prevail (>50%) within our Type I, II and III sub-samples. These observations thus suggest that while stellar migrations and inside-out growth can play a significant role in the evolution of all disk galaxy types, other factors contributing to the evolution of galaxies can overwhelm the predicted signatures of these processes. We interpret our observations through a scenario whereby Virgo cluster disk galaxies formed initially like their bretheren in the field but which, upon falling into the cluster, were transformed into their present state through external processes linked to the environment. Current disk galaxy formation models fail to reproduce these results, thus calling for adequate hydrodynamical simulations of dense galaxy environments, for which the current paper provides many constraints. [Abridged]Comment: 47 pages, 10 figures. ApJ, in press. Full resolution version available at http://www.astro.queensu.ca/~courteau/papers/migrations2012.pd

The Formation and Survival of Discs in a Lambda-CDM Universe

We study the formation of galaxies in a Lambda-CDM Universe using high resolution hydrodynamical simulations with a multiphase treatment of gas, cooling and feedback, focusing on the formation of discs. Our simulations follow eight haloes similar in mass to the Milky Way and extracted from a large cosmological simulation without restriction on spin parameter or merger history. This allows us to investigate how the final properties of the simulated galaxies correlate with the formation histories of their haloes. We find that, at z = 0, none of our galaxies contain a disc with more than 20 per cent of its total stellar mass. Four of the eight galaxies nevertheless have well-formed disc components, three have dominant spheroids and very small discs, and one is a spheroidal galaxy with no disc at all. The z = 0 spheroids are made of old stars, while discs are younger and formed from the inside-out. Neither the existence of a disc at z = 0 nor the final disc-to-total mass ratio seems to depend on the spin parameter of the halo. Discs are formed in haloes with spin parameters as low as 0.01 and as high as 0.05; galaxies with little or no disc component span the same range in spin parameter. Except for one of the simulated galaxies, all have significant discs at z > ~2, regardless of their z = 0 morphologies. Major mergers and instabilities which arise when accreting cold gas is misaligned with the stellar disc trigger a transfer of mass from the discs to the spheroids. In some cases, discs are destroyed, while in others, they survive or reform. This suggests that the survival probability of discs depends on the particular formation history of each galaxy. A realistic Lambda-CDM model will clearly require weaker star formation at high redshift and later disc assembly than occurs in our models.Comment: 14 pages, 10 figures, mn2e.cls. MNRAS in press, updated to match published versio

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function. METHODS: We performed GWAS of the rate of change in forced expiratory volume in the first second (FEV1) in 14 longitudinal, population-based cohort studies comprising 27,249 adults of European ancestry using linear mixed effects model and combined cohort-specific results using fixed effect meta-analysis to identify novel genetic loci associated with longitudinal change in lung function. Gene expression analyses were subsequently performed for identified genetic loci. As a secondary aim, we estimated the mean rate of decline in FEV1 by smoking pattern, irrespective of genotypes, across these 14 studies using meta-analysis. RESULTS: The overall meta-analysis produced suggestive evidence for association at the novel IL16/STARD5/TMC3 locus on chromosome 15 (P  =  5.71 × 10(-7)). In addition, meta-analysis using the five cohorts with ≥3 FEV1 measurements per participant identified the novel ME3 locus on chromosome 11 (P  =  2.18 × 10(-8)) at genome-wide significance. Neither locus was associated with FEV1 decline in two additional cohort studies. We confirmed gene expression of IL16, STARD5, and ME3 in multiple lung tissues. Publicly available microarray data confirmed differential expression of all three genes in lung samples from COPD patients compared with controls. Irrespective of genotypes, the combined estimate for FEV1 decline was 26.9, 29.2 and 35.7 mL/year in never, former, and persistent smokers, respectively. CONCLUSIONS: In this large-scale GWAS, we identified two novel genetic loci in association with the rate of change in FEV1 that harbor candidate genes with biologically plausible functional links to lung function

Cystatin C and Cardiovascular Disease

Background Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of creatinine-based renal function measurements. It is unclear whether this relationship is causal, arises from residual confounding, and/or is a consequence of reverse causation. Objectives The aim of this study was to use Mendelian randomization to investigate whether cystatin C is causally related to CVD in the general population. Methods We incorporated participant data from 16 prospective cohorts (n = 76,481) with 37,126 measures of cystatin C and added genetic data from 43 studies (n = 252,216) with 63,292 CVD events. We used the common variant rs911119 in CST3 as an instrumental variable to investigate the causal role of cystatin C in CVD, including coronary heart disease, ischemic stroke, and heart failure. Results Cystatin C concentrations were associated with CVD risk after adjusting for age, sex, and traditional risk factors (relative risk: 1.82 per doubling of cystatin C; 95% confidence interval [CI]: 1.56 to 2.13; p = 2.12 × 10−14). The minor allele of rs911119 was associated with decreased serum cystatin C (6.13% per allele; 95% CI: 5.75 to 6.50; p = 5.95 × 10−211), explaining 2.8% of the observed variation in cystatin C. Mendelian randomization analysis did not provide evidence for a causal role of cystatin C, with a causal relative risk for CVD of 1.00 per doubling cystatin C (95% CI: 0.82 to 1.22; p = 0.994), which was statistically different from the observational estimate (p = 1.6 × 10−5). A causal effect of cystatin C was not detected for any individual component of CVD. Conclusions Mendelian randomization analyses did not support a causal role of cystatin C in the etiology of CVD. As such, therapeutics targeted at lowering circulating cystatin C are unlikely to be effective in preventing CVD

The Eurasian Modern Pollen Database (EMPD), version 2

The Eurasian (née European) Modern Pollen Database (EMPD) was established in 2013 to provide a public database of high-quality modern pollen surface samples to help support studies of past climate, land cover, and land use using fossil pollen. The EMPD is part of, and complementary to, the European Pollen Database (EPD) which contains data on fossil pollen found in Late Quaternary sedimentary archives throughout the Eurasian region. The EPD is in turn part of the rapidly growing Neotoma database, which is now the primary home for global palaeoecological data. This paper describes version 2 of the EMPD in which the number of samples held in the database has been increased by 60 % from 4826 to 8134. Much of the improvement in data coverage has come from northern Asia, and the database has consequently been renamed the Eurasian Modern Pollen Database to reflect this geographical enlargement. The EMPD can be viewed online using a dedicated map-based viewer at https://empd2.github.io and downloaded in a variety of file formats at https://doi.pangaea.de/10.1594/PANGAEA.909130 (Chevalier et al., 2019)Swiss National Science Foundation | Ref. 200021_16959

The Eurasian Modern Pollen Database (EMPD), version 2

The Eurasian (nee European) Modern Pollen Database (EMPD) was established in 2013 to provide a public database of high-quality modern pollen surface samples to help support studies of past climate, land cover, and land use using fossil pollen. The EMPD is part of, and complementary to, the European Pollen Database (EPD) which contains data on fossil pollen found in Late Quaternary sedimentary archives throughout the Eurasian region. The EPD is in turn part of the rapidly growing Neotoma database, which is now the primary home for global palaeoecological data. This paper describes version 2 of the EMPD in which the number of samples held in the database has been increased by 60% from 4826 to 8134. Much of the improvement in data coverage has come from northern Asia, and the database has consequently been renamed the Eurasian Modern Pollen Database to reflect this geographical enlargement. The EMPD can be viewed online using a dedicated map-based viewer at https://empd2.github.io and downloaded in a variety of file formats at https://doi.pangaea.de/10.1594/PANGAEA.909130 (Chevalier et al., 2019).Peer reviewe

Association of Forced Vital Capacity with the Developmental Gene <i>NCOR2</i>

Background Forced Vital Capacity (FVC) is an important predictor of all-cause mortality in the absence of chronic respiratory conditions. Epidemiological evidence highlights the role of early life factors on adult FVC, pointing to environmental exposures and genes affecting lung development as risk factors for low FVC later in life. Although highly heritable, a small number of genes have been found associated with FVC, and we aimed at identifying further genetic variants by focusing on lung development genes. Methods Per-allele effects of 24,728 SNPs in 403 genes involved in lung development were tested in 7,749 adults from three studies (NFBC1966, ECRHS, EGEA). The most significant SNP for the top 25 genes was followed-up in 46,103 adults (CHARGE and SpiroMeta consortia) and 5,062 chi