Exploring the nanoscale origin of performance enhancement in Li1.1_{1.1}Ni0.35_{0.35}Mn0.55_{0.55}O2_2 batteries due to chemical doping

Despite significant potential as energy storage materials for electric vehicles due to their combination of high energy density per unit cost and reduced environmental and ethical concerns, Co-free lithium ion batteries based off layered Mn oxides presently lack the longevity and stability of their Co-containing counterparts. Here, we demonstrate a reduction in this performance gap via chemical doping, with Li$_{1.1}$Ni$_{0.35}$Mn$_{0.55}$O$_2$ achieving an initial discharge capacity of 159 mAhg$^{-1}$ at C/3 rate and a corresponding capacity retention of 94.3% after 150 cycles. We subsequently explore the nanoscale origins of this improvement through a combination of advanced diffraction, spectroscopy, and electron microscopy techniques, finding that optimized doping profiles lead to an improved structural and chemical compatibility between the two constituent sub-phases that characterize the layered Mn oxide system, resulting in the formation of unobstructed lithium ion pathways between them. We also directly observe a structural stabilization effect of the host compound near the surface using aberration corrected scanning transmission electron microscopy and integrated differential phase contrast imaging.Comment: 20 pages, 8 figure

Servicios y trámites de salud oportunos

La prestación de servicios de salud es una actividad que reviste una complejidad importante, no sólo por el veloz desarrollo de la tecnología, sino también, porque ese mismo desarrollo ha hecho necesario la conformación de entes cada vez más complejos IPS, EPS en donde se suman los esfuerzos de personas de diferente calificación profesional, con el uso de equipos, instalaciones y materiales, bajo la dirección de ese ente aglutinador para quien surgen importantes obligaciones y responsabilidades en el desarrollo de esa actividad. El presente trabajo, pretende analizar aspectos relacionados con la efectividad que tienen la región de Bosconia para conseguir citas médicas en las Instituciones Prestadoras de Salud, IPS, como las denominó la nueva ley de seguridad social, tienen con sus pacientes en el proceso de atenderlos o con los terceros que puedan verse afectados por su funcionamiento, por eso hemos creado la empresa SERVISALUD la cual prestamos servicios y tramites de salud mediante plataformas, de esta manera nos encárganos de conseguir las citas médicas que necesita cada paciente en tiempos oportunos y no tiene la necesidad de esperar tanto tiempo para que pueda ser atendido.The provision of health services is an activity that has an important complexity, not only because of the rapid development of technology, but also, because that same development has made it necessary to create increasingly complex IPS, EPS entities where they are added the efforts of people of different professional qualifications, with the use of equipment, facilities and materials, under the direction of that agglutinating entity for whom important obligations and responsibilities arise in the development of that activity. The present work aims to analyze aspects related to the effectiveness of the Bosconia region in obtaining medical appointments in the Lending Institutions of Health, IPS, as the new social security law called them, they have with their patients in the process of attending them or with the third parties that may be affected by its operation, that is why we have created the SERVISALUD company which provides health services and procedures through platforms, in this way we are responsible for getting the medical appointments that each patient needs in a timely manner and does not have the Need to wait so long for it to be taken care of

Potential impacts of climate change on flow regime and fish habitat in mountain rivers of the southwestern Balkans

The climate change in the Mediterranean area is expected to have significant impacts on the aquatic ecosystems and particular in the mountain rivers and streams that often host important species such as the Salmo farioides, Karaman 1938. These impacts will most possibly affect the habitat availability for various aquatic species resulting to an essential alteration of the water requirements, either for dams or other water abstractions, in order to maintain the essential levels of ecological flow for the rivers. The main scope of this study was to assess potential climate change impacts on the hydrological patterns and typical biota for a south-western Balkan mountain river, the Acheloos. The altered flow regimes under different emission scenarios of the Intergovernmental Panel on Climate Change (IPCC) were estimated using a hydrologicalmodel and based on regional climate simulations over the study area. The Indicators of Hydrologic Alteration (IHA) methodology was then used to assess the potential streamflow alterations in the studied river due to predicted climate change conditions. A fish habitat simulation method integrating univariate habitat suitability curves and hydraulic modeling techniques were used to assess the impacts on the relationships between the aquatic biota and hydrological status utilizing a sentinel species, the West Balkan trout. The most prominent effects of the climate change scenarios depict severe flow reductions that are likely to occur especially during the summer flows, changing the duration and depressing the magnitude of the natural low flow conditions. Weighted Usable Area-flow curves indicated the limitation of suitable habitat for the native trout. Finally, this preliminary application highlighted the potential of science-based hydrological and habitat simulation approaches that are relevant to both biological quality elements (fish) and current EUWater policy to serve as efficient tools for the estimation of possible climate change impacts on the south-western Balkan river ecosystems.This study was supported by the ECOFLOW project funded by the Hellenic General Secretariat of Research and Technology in the framework of the NSRF 2007-2013. The W. B. trout data collection was partially funded by the Spanish Ministry of Economy and Competitiveness with the project SCARCE (Consolider-Ingenio 2010 CSD2009-00065).Papadaki, C.; Soulis, K.; Muñoz Mas, R.; Martinez-Capel, F.; Zogaris, S.; Ntoanidis, L.; Dimitriou, E. (2016). Potential impacts of climate change on flow regime and fish habitat in mountain rivers of the southwestern Balkans. Science of the Total Environment. 540:418-428. https://doi.org/10.1016/j.scitotenv.2015.06.134S41842854

Performance of the CMS Cathode Strip Chambers with Cosmic Rays

The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns

Performance and Operation of the CMS Electromagnetic Calorimeter

The operation and general performance of the CMS electromagnetic calorimeter using cosmic-ray muons are described. These muons were recorded after the closure of the CMS detector in late 2008. The calorimeter is made of lead tungstate crystals and the overall status of the 75848 channels corresponding to the barrel and endcap detectors is reported. The stability of crucial operational parameters, such as high voltage, temperature and electronic noise, is summarised and the performance of the light monitoring system is presented

Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors

BACKGROUND: We aimed to describe the most frequently prescribed initial antiretroviral therapy (ART) regimens in recent years in HIV-positive persons in the Cohort of the Spanish HIV/AIDS Research Network (CoRIS) and to investigate factors associated with the choice of each regimen. METHODS: We analyzed initial ART regimens prescribed in adults participating in CoRIS from 2014 to 2017. Only regimens prescribed in >5% of patients were considered. We used multivariable multinomial regression to estimate Relative Risk Ratios (RRRs) for the association between sociodemographic and clinical characteristics and the choice of the initial regimen. RESULTS: Among 2874 participants, abacavir(ABC)/lamivudine(3TC)/dolutegavir(DTG) was the most frequently prescribed regimen (32.1%), followed by tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC)/elvitegravir(EVG)/cobicistat(COBI) (14.9%), TDF/FTC/rilpivirine (RPV) (14.0%), tenofovir alafenamide (TAF)/FTC/EVG/COBI (13.7%), TDF/FTC+DTG (10.0%), TDF/FTC+darunavir/ritonavir or darunavir/cobicistat (bDRV) (9.8%) and TDF/FTC+raltegravir (RAL) (5.6%). Compared with ABC/3TC/DTG, starting TDF/FTC/RPV was less likely in patients with CD4100.000 copies/mL. TDF/FTC+DTG was more frequent in those with CD4100.000 copies/mL. TDF/FTC+RAL and TDF/FTC+bDRV were also more frequent among patients with CD4<200 cells//muL and with transmission categories other than men who have sex with men. Compared with ABC/3TC/DTG, the prescription of other initial ART regimens decreased from 2014-2015 to 2016-2017 with the exception of TDF/FTC+DTG. Differences in the choice of the initial ART regimen were observed by hospitals' location. CONCLUSIONS: The choice of initial ART regimens is consistent with Spanish guidelines' recommendations, but is also clearly influenced by physician's perception based on patient's clinical and sociodemographic variables and by the prescribing hospital location

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection are often non-specific, and there is no definitive test for the accurate diagnosis of infection. The 'omics' approaches to identifying biomarkers from the host-response to bacterial infection are promising. In this study, lipidomic analysis was carried out with plasma samples obtained from febrile children with confirmed bacterial infection (n = 20) and confirmed viral infection (n = 20). We show for the first time that bacterial and viral infection produces distinct profile in the host lipidome. Some species of glycerophosphoinositol, sphingomyelin, lysophosphatidylcholine and cholesterol sulfate were higher in the confirmed virus infected group, while some species of fatty acids, glycerophosphocholine, glycerophosphoserine, lactosylceramide and bilirubin were lower in the confirmed virus infected group when compared with confirmed bacterial infected group. A combination of three lipids achieved an area under the receiver operating characteristic (ROC) curve of 0.911 (95% CI 0.81 to 0.98). This pilot study demonstrates the potential of metabolic biomarkers to assist clinicians in distinguishing bacterial from viral infection in febrile children, to facilitate effective clinical management and to the limit inappropriate use of antibiotics

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements