A micromechanics based constitutive model for fibre reinforced cementitious composites

A new constitutive model for fibre reinforced cementitious composites based on micromechanical solutions is proposed. The model employs a two-phase composite based on the Eshelby matrix-inclusion solution and the Mori-Tanaka homogenization scheme and also simulates directional microcracking. An exterior point Eshelby based criterion is employed to model crack-initiation in the matrix-inclusion interface. Microcrack surfaces are assumed to be rough and able to regain contact under both normal and shear displacements. Fibres are included into the formulation in both cracked and uncracked conditions. Once cracks start to develop, the crack-bridging action of fibres is simulated using a local constitutive equation that accounts for the debonding and pull-out of fibre groups with different orientations. It is shown that the combination of the rough microcrack and fibre-bridging sub-models allows microcracking behaviour deriving from both tensile and compressive loads to be modelled in a unified manner. This ability to model tensile and compressive behaviour using the same micromechanical mechanisms is considered to be a particularly attractive feature of the formulation, which removes the need for multi-parameter triaxial yield surfaces and evolution functions that bedevil many competitor models. The model is successfully validated using a series of examples based on experimental test data

A plastic-damage constitutive model for the finite element analysis of fibre reinforced concrete

A unique constitutive model for fibre reinforced concrete (FRC) is presented, which combines a number of mechanics-based sub models for the simulation of directional cracking, rough crack contact and the crack-bridging action of fibres. The model also contains a plasticity component to simulate compressive behaviour. The plasticity component employs a frictional hardening/softening function which considers the variation of compressive strength and strain at peak stress with fibre content. Numerical results from a range of single-point and finite element simulations of experimental tests show that the model captures the characteristic behaviour of conventional fibre reinforced concrete with good accuracy

Micromechanics-driven variational method for diffuse-to-localised fracture in quasi-brittle solids

A novel multiscale variational method for modelling fracture propagation is proposed. The method employs strong discontinuity kinematics enhancement, enabling macroscopic cracks to be modelled explicitly, while minimum remeshing is ensured. In addition, the response of quadrature points in the bulk is up-scaled using a Micromechanical continua, which enables the evolution of directional micro-defects (e.g. microcracks) without venturing into prohibitive computational burden. Noticeably, the method allows the Micromechanical continua to interact with macroscopic cracks. The framework is conveniently formulated as a variational setting to provide a minimum energy solution. The new computational framework has been found to diagnose realistic failure mechanisms in quasi-brittle materials

Assessing Tourists’ Preferences for Recreational Trips in National and Natural Parks as a Premise for Long-Term Sustainable Management Plans

Sustainable tourism management plans rely on relevant and consistent information about factors that can influence the decision to visit a protected area. This paper uses the choice experiment method to investigate tourists’ preferences with regard to recreational trip characteristics in national and natural parks in Romania. An on-site survey questionnaire was administered to visitors. The multinomial logit model was employed to investigate the preference orderings of the identified groups of recreational users. Overall, results indicate that tourists gain benefits after visiting the parks. Main preference differences were found for information sources and location of campsites. Visitors who stated that the park was the main trip destination were willing to have access to more information sources, the marks on trails being insufficient. Camping is preferred only in organized places, expressing the concern for environmental protection. The results of this study have management implications, highlighting the importance of assessing tourists’ preferences as a foundation for developing sustainable tourism strategies

Advancements in bacteria based self-healing concrete and the promise of modelling

In the last two decades self-healing of concrete through microbial based carbonate precipitation has emerged as a promising technology for making concrete structures more resilient and sustainable. Currently, progress in the field is achieved mainly through physical experiments, but their duration and cost are barriers to innovation and keep the number of large scale applications still very limited. Modelling and simulation of the phenomena underlying microbial based healing of concrete may provide a key to complement the experimental efforts, but their development is still in its infancy. In this review, we briefly present the field, introduce some key aspects emerged from the experiments, present the main ongoing developments in modelling and simulation of mineral and microbial systems, and discuss how their synergy may be accomplished to speed up progress in the near future

Peri-operative red blood cell transfusion in neonates and infants: NEonate and Children audiT of Anaesthesia pRactice IN Europe: A prospective European multicentre observational study

BACKGROUND: Little is known about current clinical practice concerning peri-operative red blood cell transfusion in neonates and small infants. Guidelines suggest transfusions based on haemoglobin thresholds ranging from 8.5 to 12 g dl-1, distinguishing between children from birth to day 7 (week 1), from day 8 to day 14 (week 2) or from day 15 (≥week 3) onwards. OBJECTIVE: To observe peri-operative red blood cell transfusion practice according to guidelines in relation to patient outcome. DESIGN: A multicentre observational study. SETTING: The NEonate-Children sTudy of Anaesthesia pRactice IN Europe (NECTARINE) trial recruited patients up to 60 weeks' postmenstrual age undergoing anaesthesia for surgical or diagnostic procedures from 165 centres in 31 European countries between March 2016 and January 2017. PATIENTS: The data included 5609 patients undergoing 6542 procedures. Inclusion criteria was a peri-operative red blood cell transfusion. MAIN OUTCOME MEASURES: The primary endpoint was the haemoglobin level triggering a transfusion for neonates in week 1, week 2 and week 3. Secondary endpoints were transfusion volumes, 'delta haemoglobin' (preprocedure - transfusion-triggering) and 30-day and 90-day morbidity and mortality. RESULTS: Peri-operative red blood cell transfusions were recorded during 447 procedures (6.9%). The median haemoglobin levels triggering a transfusion were 9.6 [IQR 8.7 to 10.9] g dl-1 for neonates in week 1, 9.6 [7.7 to 10.4] g dl-1 in week 2 and 8.0 [7.3 to 9.0] g dl-1 in week 3. The median transfusion volume was 17.1 [11.1 to 26.4] ml kg-1 with a median delta haemoglobin of 1.8 [0.0 to 3.6] g dl-1. Thirty-day morbidity was 47.8% with an overall mortality of 11.3%. CONCLUSIONS: Results indicate lower transfusion-triggering haemoglobin thresholds in clinical practice than suggested by current guidelines. The high morbidity and mortality of this NECTARINE sub-cohort calls for investigative action and evidence-based guidelines addressing peri-operative red blood cell transfusions strategies. TRIAL REGISTRATION: ClinicalTrials.gov, identifier: NCT02350348

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)

From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions

Residents’ Perception of Destination Quality: Key Factors for Sustainable Rural Development

Tourism represents a viable alternative for economic activities in rural areas, and improves the living standards of the communities. The aim of the paper is to assess residents’ perceptions towards tourism destination quality in the North-West Development Region of Romania using the following items: natural attractions: cultural and social attractions; accommodation; food; availability of transportation to destination area; quality of information and communication; hospitality of host community; feeling of security and safety. A survey was conducted to collect the data and a total of 433 questionnaires were validated and analyzed. Descriptive and inferential statistics (Principal component analysis, ANOVA, Scheffe multiple range test) were used to analyze the data. Results show that there are statistically significant differences in residents’ perceptions between counties. Two of the components of destination quality (general infrastructure and tourism potential) are affected by the gender of residents, while the level of education has no significant effect. A weak and indirect correlation was found between the age of residents and their perception towards a quality destination. This study makes two contributions to the existing literature. First, a questionnaire was developed based on the QUALITEST tool adapted to the realities of the research area. Second, we analyzed the perception of residents towards a quality destination in relation to their socio-demographic characteristics and county of residence. Understanding the implications of tourism development from the residents’ point of view helps to increase knowledge about the factors affecting the long-term, sustainable success of tourism destinations

Gender Differences in the Levels of Periodontal Destruction, Behavioral Risk Factors and Systemic Oxidative Stress in Ischemic Stroke Patients: A Cohort Pilot Study

Background: Due to the higher frequency of ischemic stroke in men compared to women, we aimed to determine if gender differences exist regarding periodontal status and several plasma biomarkers in patients with a recent large artery atherosclerosis ischemic stroke (IS). Material and methods: Patients with their first IS within less than six weeks who were able to undergo periodontal examinations were evaluated. Demographic data, periodontal status, oxidative stress parameters/plasma antioxidant capacity, and C-reactive protein in patients who suffered a recent large artery atherosclerosis ischemic stroke were reccorded. Results: 93 patients were included in the study. More men were smokers (12/57 vs. 3/36) and consumed alcohol (17/57 vs. 3/36), and more women had higher glycemic values (p = 0.023), total cholesterol (p < 0.001), LDL (low-density lipoprotein)-cholesterol (p = 0.010), and HDL (high-density lipoprotein)-cholesterol (p = 0.005) levels. Significantly more men than women had moderate plus severe periodontal disease (p = 0.018), significantly higher levels of nitric oxide (p = 0.034), and significantly lower levels of total antioxidant capacity (p = 0.028). Conclusions: In this pilot study, men seem to be more prone to oxidative stress and to develop more severe forms of periodontitis among patients with stroke, but the results need validation on a larger sample