289 research outputs found

    Saberes previos: su importancia en la promoción de aprendizajes

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    El Curso Introducción a las Ciencias Agrarias y Forestales, del Departamento de Desarrollo Rural, es una materia propedéutica de primer año de la carrera de Ingeniería Agronómica y Forestal de la UNLP., que se desarrolla desde el año 1999. Durante los distintos ciclos en los que se ha desarrollado el curso, se privilegiaron los contenidos y actividades que promueven aprendizajes significativos, mediante el contacto de los estudiantes con diferentes realidades, a las que se enfrentarán en su vida profesional, intentando desarrollar diversas habilidades necesarias para la práctica profesional. Si bien la cantidad de estudiantes ingresantes se mantiene constante en los últimos años, los datos del año 2015 sobre un total de 318 inscriptos, el 59 % provienen de escuelas públicas y un 41 % del sector privado. El trabajo hace un análisis de conocimientos previos de los estudiantes ingresantes sobre temas que son abordados en el curso, y las estrategias de aprendizaje que se abordan en la cursada para la promoción de aprendizajes significativos.Eje 1: La enseñanza universitaria en el contexto actual: transformaciones y propuestas. Reflexiones y experiencias en la enseñanza de las Ciencias Exactas.Secretaría de Asuntos Académico

    Los saberes previos: una base para mirar la educación en el aula

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    El Curso Introducción a las Ciencias Agrarias y Forestales, del Departamento de Desarrollo Rural, es una materia propedéutica de primer año de la carrera de Ingeniería Agronómica y Forestal de la UNLP., que se desarrolla desde el año 1999. Durante los distintos ciclos en los que se ha desarrollado el curso, se privilegiaron los contenidos y actividades que promueven aprendizajes significativos, mediante el contacto de los estudiantes con diferentes realidades, a las que se enfrentarán en su vida profesional, intentando desarrollar diversas habilidades necesarias para la práctica profesional. Si bien la cantidad de estudiantes ingresantes se mantiene constante en los últimos años, los datos del año 2015 sobre un total de 318 inscriptos, el 59 % provienen de escuelas públicas y un 41 % del sector privado. El trabajo muestra una primera aproximación de análisis de conocimientos previos de los estudiantes ingresantes sobre temas que son abordados en el curso, y las estrategias de aprendizaje que se abordan en la cursada para la promoción de aprendizajes significativos.Facultad de Ciencias Agrarias y Forestale

    Effect of tides on the orbital evolution of the redback system PSR 1723-2837

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    The standard model of stellar evolution in close binary systems assumes that during mass transfer episodes, the system is in a synchronized and circularized state. Remarkably, the redback system PSR J1723–2837 has an orbital period derivative P˙orb too large to be explained by this model. Motivated by this fact, we investigate the action of tidal forces in between two consecutive mass transfer episodes for a system under irradiation feedback, which is a plausible progenitor for PSR J1723–2837. We base our analysis on Hut’s treatment of equilibrium tidal evolution, generalized by considering the donor as a two layers object that may not rotate as a rigid body. We also analyse three different relations for the viscosity with the tidal forcing frequency. We found that the large value measured for P˙orb can be reached by systems where the donor star rotates slower (by few per cent) than the orbit just after mass transfer episodes. Van Staden & Antoniadis have observed this object and reported a lack of synchronism, opposite to that required by the Hut’s theory to account for the observed P˙orb⁠. Motivated by this discrepancy, we analyse photometric data obtained by the spacecraft Kepler second mission K2, with the purpose of identifying the periods present in PSR J1723–2837. We notice several periods close to those of the orbit and the rotation. The obtained periods pattern reveals the presence of a more complex phenomenology, which would not be well described in the frame of the weak friction model of equilibrium tides.Instituto de Astrofísica de La Plat

    Materias propedéuticas: la mirada de los estudiantes que finalizaron el curso de Introducción a las Ciencias Agrarias y Forestales de La Plata

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    Desde el Curso de Introducción a las Ciencias Agrarias y Forestales, se realiza anualmente un relevamiento de la opinión y percepciones de los estudiantes acerca de la enseñanza al finalizar la cursada. Se utiliza un instrumento de evaluación con preguntas abiertas y cerradas, en relación al desarrollo de los teóricos y prácticos, las salidas a campo, las modalidades de trabajo en aula, el desempeño docente, las formas de evaluación de los alumnos. Los resultados que se muestran corresponden a las encuestas realizadas desde el año 2003 hasta el año 2011, con las valoraciones que hacen los estudiantes del proceso de enseñanza aprendizaje y que posibilita repensar la práctica docente. Las conclusiones preliminares reflejan por un lado el interés de los alumnos en los conocimientos abordados, el análisis que se realiza de la realidad del sector en las salidas a campo y en el aula, por el otro lado la necesidad de rediseñar el instrumento de evaluación utilizado para profundizar la riqueza explicativa que realizan los estudiantes.Eje temático 1: Problemáticas y alternativas de mejora de la enseñanza c - Los enfoques y experiencias en cátedras con orientación propedéuticaFacultad de Ciencias Agrarias y Forestale

    Human Immunodeficiency Virus/Hepatits C Virus Coinfection in Spain: Elimination Is Feasible, but the Burden of Residual Cirrhosis Will Be Significant

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    Background: We assessed the prevalence of antibodies against hepatitis C virus (HCV-Abs) and active HCV infection in patients infected with human immunodeficiency virus (HIV) in Spain in 2016 and compared the results with those of similar studies performed in 2002, 2009, and 2015. Methods: The study was performed in 43 centers during October-November 2016. The sample was estimated for an accuracy of 2% and selected by proportional allocation and simple random sampling. During 2016, criteria for therapy based on direct-acting antiviral agents (DAA) were at least significant liver fibrosis, severe extrahepatic manifestations of HCV, and high risk of HCV transmissibility. Results: The reference population and the sample size were 38904 and 1588 patients, respectively. The prevalence of HCV-Abs in 2002, 2009, 2015, and 2016 was 60.8%, 50.2%, 37.7%, and 34.6%, respectively (P trend <.001, from 2002 to 2015). The prevalence of active HCV in 2002, 2009, 2015, and 2016 was 54.0%, 34.0%, 22.1%, and 11.7%, respectively (P trend <.001). The anti-HCV treatment uptake in 2002, 2009, 2015, and 2016 was 23.0%, 48.0%, 59.3%, and 74.7%, respectively (P trend <.001). In 2016, HCV-related cirrhosis was present in 7.6% of all HIV-infected individuals, 15.0% of patients with active HCV, and 31.5% of patients who cleared HCV after anti-HCV therapy. Conclusions: Our findings suggest that with universal access to DAA-based therapy and continued efforts in prevention and screening, it will be possible to eliminate active HCV among HIV-infected individuals in Spain in the short term. However, the burden of HCV-related cirrhosis will continue to be significant among HIV-infected individuals.This work was funded by grant Ref. no. GLD14-00279 from the GILEAD Fellowship Programme (Spain) and by the Spanish AIDS Research Network (RD16/0025/0017, RD16/0025/0018) that is included in the Spanish I+D+I Plan and is co-financed by ISCIII-Subdirección General de Evaluacion and European Funding for Regional Development (FEDER).S

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

    Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019

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    Altres ajuts: Spanish AIDS Research Network; European Funding for Regional Development (FEDER).Objectives: We assessed the prevalence of anti-hepatitis C virus (HCV) antibodies and active HCV infection (HCV-RNA-positive) in people living with HIV (PLWH) in Spain in 2019 and compared the results with those of four similar studies performed during 2015-2018. Methods: The study was performed in 41 centres. Sample size was estimated for an accuracy of 1%. Patients were selected by random sampling with proportional allocation. Results: The reference population comprised 41 973 PLWH, and the sample size was 1325. HCV serostatus was known in 1316 PLWH (99.3%), of whom 376 (28.6%) were HCV antibody (Ab)-positive (78.7% were prior injection drug users); 29 were HCV-RNA-positive (2.2%). Of the 29 HCV-RNA-positive PLWH, infection was chronic in 24, it was acute/recent in one, and it was of unknown duration in four. Cirrhosis was present in 71 (5.4%) PLWH overall, three (10.3%) HCV-RNA-positive patients and 68 (23.4%) of those who cleared HCV after anti-HCV therapy (p = 0.04). The prevalence of anti-HCV antibodies decreased steadily from 37.7% in 2015 to 28.6% in 2019 (p < 0.001); the prevalence of active HCV infection decreased from 22.1% in 2015 to 2.2% in 2019 (p < 0.001). Uptake of anti-HCV treatment increased from 53.9% in 2015 to 95.0% in 2019 (p < 0.001). Conclusions: In Spain, the prevalence of active HCV infection among PLWH at the end of 2019 was 2.2%, i.e. 90.0% lower than in 2015. Increased exposure to DAAs was probably the main reason for this sharp reduction. Despite the high coverage of treatment with direct-acting antiviral agents, HCV-related cirrhosis remains significant in this population

    Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

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    Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

    Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

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    A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV
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