6 research outputs found
'Only' and association with negative antonyms
- Author
- Publication venue
- Massachusetts Institute of Technology
- Publication date
- 01/01/2013
- Field of study
Thesis (Ph. D. in Linguistics)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, 2013.Cataloged from PDF version of thesis. "September 2013."Includes bibliographical references (pages 138-144).A problem is detected in how only, traditionally viewed, associates with Negative Quantifiers (NQs) like few, [at most n], and [less than n]. The predicted meanings, which negate the stronger alternatives of the relevant NQs, is shown to be incorrect. The attested meanings are shown to be truth-conditionally equivalent to the result of removing only, hence giving the illusion that only is vacuous. It is further observed that, given an NQ, sentences where only appears to be vacuous become ungrammatical when the NQ is replaced with its positive counterpart. I argue for a view that relates the two phenomena: the ungrammaticality of the only-positive cases explains the unavailability of the predicted meanings in only-negative cases. The attested readings for the negatives, where only appears to be vacuous, is derived from LFs that feature a silent existential quantifier above the NQ. Thesis supervisor:by Sam Al Khatib.Ph.D.in Linguistic
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati Cristiana
- Abbas Kaja M.
- Abbasi Mohammad
- Abbasi-Kangevari Mohsen
- Abbasifard Mitra
- Abbastabar Hedayat
- Abd El Razek Hassan Magdy
- Abd El Razek Muhammed Magdy
- Abd-Allah Foad
- Abdelalim Ahmed
- Abdollahi Mohammad
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abdullah Kanaan Hamagharib
- Abedi Aidin
- Abedi Parisa
- Abegaz Kedir Hussein
- Abolhassani Hassan
- Abosetugn Akine Eshete
- Aboyans Victor
- Abrams Elissa M.
- Abreu Lucas Guimaraes
- Abrigo Michael R. M.
- Abu Haimed Abdulaziz Khalid
- Abu-Gharbieh Eman
- Abu-Raddad Laith Jamal
- Abualhasan Ahmed
- Abushouk Abdelrahman I.
- Acebedo Alyssa
- Ackerman Ilana N.
- Adabi Maryam
- Adair Tim
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adedeji Isaac Akinkunmi
- Adekanmbi Victor
- Adelson Jaimie D.
- Adeoye Abiodun Moshood
- Adetokunboh Olatunji O.
- Adham Davoud
- Advani Shailesh M.
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agardh Emilie E.
- Agarwal Gina
- Agasthi Pradyumna
- Agesa Kareha M.
- Aghaali Mohammad
- Aghamir Seyed Mohammad Kazem
- Agrawal Anurag
- Ahmad Tauseef
- Ahmadi Alireza
- Ahmadi Keivan
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmadpour Ehsan
- Ahmed Muktar Beshir
- Aji Budi
- Akalu Temesgen Yihunie
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akombi Blessing
- Akunna Chisom Joyqueenet
- Al-Aly Ziyad
- Al-Mekhlafi Hesham M.
- Al-Raddadi Rajaa M.
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Samiah
- Alam Tahiya
- Alanezi Fahad Mashhour
- Alanzi Turki M.
- Albertson Samuel B.
- Alcalde-Rabanal Jacqueline Elizabeth
- Alema Niguse Meles
- Alemu Biresaw Wassihun
- Alemu Yihun Mulugeta
- Alhabib Khalid F.
- Alhassan Robert Kaba
- Ali Muhammad
- Ali Saqib
- Alicandro Gianfranco
- Alijanzadeh Mehran
- Alinia Cyrus
- Alipour Vahid
- Alizade Hesam
- Aljunid Syed Mohamed
- Alla Francois
- Allebeck Peter
- Almadi Majid Abdulrahman Hamad
- Almasi Ali
- Almasi-Hashiani Amir
- Almasri Nihad A.
- Almulhim Abdulaziz M.
- Alonso Jordi
- Altirkawi Khalid A.
- Alumran Arwa Khalid
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J.
- Amare Azmeraw T.
- Amare Bekalu
- Amini Saeed
- Amini-Rarani Mostafa
- Aminorroaya Arya
- Amiri Fatemeh
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- Amugsi Dickson A.
- Amul Gianna Gayle Herrera
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- Ancuceanu Robert
- Anderlini Deanna
- Anderson Jason A.
- Andrei Catalina Liliana
- Andrei Tudorel
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- Antony Catherine M.
- Antriyandarti Ernoiz
- Anvari Davood
- Anwer Razique
- Appiah Seth Christopher Yaw
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- Arabloo Jalal
- Aravkin Aleksandr Y.
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- Aremu Olatunde
- Ariani Filippo
- Aripov Timur
- Armoon Bahram
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- Arzani Afsaneh
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- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens
Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016 : a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abajobir Amanuel Alemu
- Abajobir Amanuel Alemu
- Abbafati Cristiana
- Abbafati Cristiana
- Abbas Kaja M
- Abbas Kaja M
- Abd-Allah Foad
- Abd-Allah Foad
- Abera Semaw Ferede
- Abera Semaw Ferede
- Aboyans Victor
- Aboyans Victor
- Adetokunboh Olatunji
- Adetokunboh Olatunji
- Afshin Ashkan
- Afshin Ashkan
- Agrawal Anurag
- Agrawal Anurag
- Ahmadi Alireza
- Ahmadi Alireza
- Ahmed Muktar Beshir
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Aichour Miloud Taki Eddine
- Aiyar Sneha
- Aiyar Sneha
- Al-Aly Ziyad
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Eyadhy Ayman
- Al-Raddadi Rajaa
- Al-Raddadi Rajaa
- Alahdab Fares
- Alahdab Fares
- Alam Khurshid
- Alam Khurshid
- Alam Noore
- Alam Noore
- Alam Tahiya
- Alam Tahiya
- Alene Kefyalew Addis
- Alene Kefyalew Addis
- Ali Syed Danish
- Ali Syed Danish
- Alizadeh-Navaei Reza
- Alizadeh-Navaei Reza
- Alkaabi Juma M
- Alkaabi Juma M
- Alkerwi Ala'a
- Alkerwi Ala'a
- Alla François
- Alla François
- Allebeck Peter
- Allebeck Peter
- Allen Christine
- Allen Christine
- Alsharif Ubai
- Alsharif Ubai
- Altirkawi Khalid A
- Altirkawi Khalid A
- Alvis-Guzman Nelson
- Alvis-Guzman Nelson
- Amare Azmeraw T
- Amare Azmeraw T
- Amini Erfan
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- Ammar Walid
- Ammar Walid
- Amoako Yaw Ampem
- Amoako Yaw Ampem
- Anber Nahla
- Anber Nahla
- Andersen Hjalte H
- Andersen Hjalte H
- Andrei Catalina Liliana
- Andrei Catalina Liliana
- Androudi Sofia
- Androudi Sofia
- Ansari Hossein
- Ansari Hossein
- Antonio Carl Abelardo T
- Antonio Carl Abelardo T
- Anwari Palwasha
- Anwari Palwasha
- Arora Megha
- Arora Megha
- Artaman Al
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- Aryal Krishna Kumar
- Aryal Krishna Kumar
- Asayesh Hamid
- Asayesh Hamid
- Asgedom Solomon W
- Asgedom Solomon W
- Atey Tesfay Mehari
- Atey Tesfay Mehari
- Avila-Burgos Leticia
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel G
- Avokpaho Euripide Frinel G
- Awasthi Ashish
- Awasthi Ashish
- Babalola Tesleem Kayode
- Babalola Tesleem Kayode
- Bacha Umar
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- Balakrishnan Kalpana
- Balakrishnan Kalpana
- Barac Aleksandra
- Barac Aleksandra
- Barboza Miguel A
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- Barker-Collo Suzanne L
- Barker-Collo Suzanne L
- Barquera Simon
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- Barregard Lars
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- Barrero Lope H
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- Baune Bernhard T
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- Bedi Neeraj
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- Beghi Ettore
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- Bekele Bayu Begashaw
- Bekele Bayu Begashaw
- Bell Michelle L
- Bell Michelle L
- Bennett James R
- Bennett James R
- Bensenor Isabela M
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- Berhane Adugnaw
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- Bernabé Eduardo
- Bernabé Eduardo
- Betsu Balem Demtsu
- Betsu Balem Demtsu
- Beuran Mircea
- Beuran Mircea
- Bhatt Samir
- Bhatt Samir
- Biadgilign Sibhatu
- Biadgilign Sibhatu
- Bienhoff Kelly
- Bienhoff Kelly
- Bikbov Boris
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- Bisanzio Donal
- Bisanzio Donal
- Bourne Rupert RA
- Bourne Rupert RA
- Breitborde Nicholas JK
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- Bulto Lemma Negesa Bulto
- Bulto Lemma Negesa Bulto
- Bumgarner Blair R
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- Butt Zahid A
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- Béjot Yannick
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- Cahuana-Hurtado Lucero
- Cahuana-Hurtado Lucero
- Cameron Ewan
- Cameron Ewan
- Campuzano Julio Cesar
- Campuzano Julio Cesar
- Car Josip
- Car Josip
- Carrero Juan Jesus
- Carrero Juan Jesus
- Carter Austin
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- Casey Daniel C
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- Castañeda-Orjuela Carlos A
- Castañeda-Orjuela Carlos A
- Catalá-López Ferrán
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- Charlson Fiona J
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- Chibueze Chioma Ezinne
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- Chimed-Ochir Odgerel
- Chimed-Ochir Odgerel
- Chisumpa Vesper Hichilombwe
- Chisumpa Vesper Hichilombwe
- Chitheer Abdulaal A
- Chitheer Abdulaal A
- Christopher Devasahayam Jesudas
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- Ciobanu Liliana G
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- Cirillo Massimo
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- Cohen Aaron J
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- Colombara Danny
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- Cooper Cyrus
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- Cowie Benjamin C
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- Criqui Michael H
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- Cárdenas Rosario
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- Dandona Lalit
- Dandona Lalit
- Dandona Rakhi
- Dandona Rakhi
- Dargan Paul I
- Dargan Paul I
- das Neves José
- das Neves José
- Davitoiu Dragos V
- Davitoiu Dragos V
- Davletov Kairat
- Davletov Kairat
- de Courten Barbora
- de Courten Barbora
- Defo Barthelemy Kuate
- Defo Barthelemy Kuate
- Degenhardt Louisa
- Degenhardt Louisa
- Deiparine Selina
- Deiparine Selina
- Deribe Kebede
- Deribe Kebede
- Deribew Amare
- Deribew Amare
- Dey Subhojit
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- Dicker Daniel
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- Ding Eric L
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- Djalalinia Shirin
- Djalalinia Shirin
- Do Huyen Phuc
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- Doku David Teye
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- Douwes-Schultz Dirk
- Douwes-Schultz Dirk
- Driscoll Tim R
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- Dubey Manisha
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- Duncan Bruce Bartholow
- Duncan Bruce Bartholow
- Echko Michelle
- Echko Michelle
- El-Khatib Ziad Ziad
- El-Khatib Ziad Ziad
- Ellingsen Christian Lycke
- Ellingsen Christian Lycke
- Enayati Ahmadali
- Enayati Ahmadali
- Ermakov Sergey Petrovich
- Ermakov Sergey Petrovich
- Erskine Holly E
- Erskine Holly E
- Eskandarieh Sharareh
- Eskandarieh Sharareh
- Esteghamati Alireza
- Esteghamati Alireza
- Estep Kara
- Estep Kara
- Farinha Carla Sofia E Sa
- Farinha Carla Sofia E Sa
- Faro André
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- Farzadfar Farshad
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- Feigin Valery L
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- Fereshtehnejad Seyed-Mohammad
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- Fernandes João C
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- Ferrari Alize J
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- Feyissa Tesfaye Regassa
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- Filip Irina
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- Finegold Samuel
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- Fischer Florian
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- Fitzmaurice Christina
- Fitzmaurice Christina
- Flaxman Abraham D
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- Foigt Nataliya
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- Frank Tahvi
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- Fraser Maya
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- Fullman Nancy
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- Furtado Joao M
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- Fürst Thomas
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- Gakidou Emmanuela
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- Garcia-Basteiro Alberto L
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- Gebre Teshome
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- Gebregergs Gebremedhin Berhe
- Gebregergs Gebremedhin Berhe
- Gebrehiwot Tsegaye Tewelde
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- Gebremichael Delelegn Yilma
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- Geleijnse Johanna M
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- Gesesew Hailay Abrha
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- Gething Peter W
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- Gillum Richard F
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- Giref Ababi Zergaw
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- Giroud Maurice
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- Giussani Giorgia
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- Godwin William W
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- Goulart Alessandra Carvalho
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- Griswold Max
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- Gupta Parkash C
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- Gupta Rajeev
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- Gupta Tanush
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- Gupta Vipin
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- Haagsma Juanita A
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- Hafezi-Nejad Nima
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- Hailu Alemayehu Desalegne
- Hailu Alemayehu Desalegne
- Hailu Gessessew Bugssa
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- Hamadeh Randah Ribhi
- Hamadeh Randah Ribhi
- Hambisa Mitiku Teshome
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- Hamidi Samer
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- Hammami Mouhanad
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- Hancock Jamie
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- Hareri Habtamu Abera
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- Hassanvand Mohammad Sadegh
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- Havmoeller Rasmus
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- Hay Simon I
- Hay Simon I
- He Fei
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- Hedayati Mohammad T
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- Henry Nathaniel J
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- Heredia-Pi Ileana Beatriz
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- Herteliu Claudiu
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- Hoek Hans W
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- Horino Masako
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- Horita Nobuyuki
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- Hostiuc Sorin
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- Ikeda Chad
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- Ileanu Bogdan Vasile
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- Irenso Asnake Ararsa
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- Islam Sheikh Mohammed Shariful
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- Jayaraman Sudha P
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- Jeemon Panniyammakal
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- Jha Vivekanand
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- John Denny
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- Johnson Sarah Charlotte
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- Jonas Jost B
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- Jürisson Mikk
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- Kabir Zubair
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- Kahsay Amaha
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- Kamal Ritul
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- Karimi Seyed M
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- Kasaeian Amir
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- Kassaw Nigussie Assefa
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- Katikireddi Srinivasa Vittal
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- Kawakami Norito
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- Keiyoro Peter Njenga
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- Kemmer Laura
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- Kesavachandran Chandrasekharan Nair
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- Khader Yousef Saleh
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- Khan Ejaz Ahmad
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- Khang Young-Ho
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- Khoja Abdullah Tawfih Abdullah
- Khoja Abdullah Tawfih Abdullah
- Khosravi Ardeshir
- Khosravi Ardeshir
- Khosravi Mohammad Hossein
- Khosravi Mohammad Hossein
- Khubchandani Jagdish
- Khubchandani Jagdish
- Kiadaliri Aliasghar Ahmad
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- Kim Daniel
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- Kim Yun Jin
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- Kimokoti Ruth W
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- Kissoon Niranjan
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- Knudsen Ann Kristin
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- Kopec Jacek A
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- Koul Parvaiz A
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- Koyanagi Ai
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- Kulikoff Xie Rachel
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- Kumar Pushpendra
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- Kyu Hmwe H
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- Lal Dharmesh Kumar
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- Lan Qing
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- Leigh James
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- Levi Miriam
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- Li Kappe Darya
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- Li Yongmei
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- Liang Xiaofeng
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- Liben Misgan Legesse
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- Lim Stephen S
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- Liu Angela
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- Liu Patrick Y
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- Liu Yang
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- Lodha Rakesh
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- Logroscino Giancarlo
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- Lopez Alan D
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- Lorkowski Stefan
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- Lotufo Paulo A
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- Lozano Rafael
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- Lucas Timothy CD
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- Ma Stefan
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- Macarayan Erlyn Rachelle King
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- Maddison Emilie R
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- Magdy Abd El Razek Mohammed
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- Majdan Marek
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- Majdzadeh Reza
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- Majeed Azeem
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- Malekzadeh Reza
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- Malhotra Rajesh
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- Malta Deborah Carvalho
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- Manguerra Helena
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- Manyazewal Tsegahun
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- Mapoma Chabila C
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- Marczak Laurie B
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- Markos Desalegn
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- Martinez-Raga Jose
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- Martins-Melo Francisco Rogerlândio
- Martins-Melo Francisco Rogerlândio
- Martopullo Ira
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- McAlinden Colm
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- McGaughey Madeline
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- Memiah Peter
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- Memish Ziad A
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- Mengesha Melkamu Merid
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- Mengistu Desalegn Tadese
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- Menota Bereket Gebremichael
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- Mensah George A
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- Millear Anoushka
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- Miller Ted R
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- Minnig Shawn
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- Mirarefin Mojde
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- Mirrakhimov Erkin M
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- Misganaw Awoke
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- Mishra Shiva Raj
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- Mohamed Ibrahim Abdelmageem
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- Mohammad Karzan Abdulmuhsin
- Mohammad Karzan Abdulmuhsin
- Mohammadi Alireza
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- Mohammed Shafiu
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- Mokdad Ali H
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- Mola Glen Liddell D
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- Mollenkopf Sarah K
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- Molokhia Mariam
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- Monasta Lorenzo
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- Montañez Julio C
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- Montico Marcella
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- Mooney Meghan D
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- Moradi-Lakeh Maziar
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- Moraga Paula
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- Morawska Lidia
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- Morozoff Chloe
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- Morrison Shane D
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- Mountjoy-Venning Cliff
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- Mruts Kalayu Birhane
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- Muller Kate
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- Murray Christopher JL
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- Murthy Gudlavalleti Venkata Satyanarayana
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- Musa Kamarul Imran
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- Nachega Jean B
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- Naghavi Mohsen
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- Naheed Aliya
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- Naldi Luigi
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- Nangia Vinay
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- Nascimento Bruno Ramos
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- Nasher Jamal T
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- Natarajan Gopalakrishnan
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- Negoi Ionut
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- Ngunjiri Josephine Wanjiku
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- Nguyen Cuong Tat
- Nguyen Cuong Tat
- Nguyen Grant
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- Nguyen Minh
- Nguyen Minh
- Nguyen Quyen Le
- Nguyen Quyen Le
- Nguyen Trang Huyen
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- Ningrum Dina Nur Anggraini
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- Nong Vuong Minh
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- Noubiap Jean Jacques N
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- Ogbo Felix Akpojene
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- Oh In-Hwan
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- Olagunju Andrew Toyin
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- Olsen Helen E
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- Olusanya Bolajoko Olubukunola
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Olusanya Jacob Olusegun
- Ong Kanyin
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- Opio John Nelson
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- Oren Eyal
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- Ortiz Alberto
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- Osman Majdi
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- Ota Erika
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- PA Mahesh
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- Pacella Rosana E
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- Pakhale Smita
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- Pana Adrian
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- Panda Basant Kumar
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- Panda-Jonas Songhomitra
- Panda-Jonas Songhomitra
- Papachristou Christina
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- Park Eun-Kee
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- Purcell Caroline
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- Qorbani Mostafa
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- Quintanilla Beatriz Paulina Ayala
- Quintanilla Beatriz Paulina Ayala
- Radfar Amir
- Radfar Amir
- Rafay Anwar
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- Rahimi-Movaghar Vafa
- Rahimi-Movaghar Vafa
- Rahman Mahfuzar
- Rahman Mahfuzar
- Rahman Mohammad Hifz Ur
- Rahman Mohammad Hifz Ur
- Rai Rajesh Kumar
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- Ranabhat Chhabi Lal
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- Rankin Zane
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- Rao Puja C
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- Rath Goura Kishor
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- Rawaf Salman
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- Ray Sarah E
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- Rehm Jürgen
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- Reiner Robert C
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- Reitsma Marissa B
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- Remuzzi Giuseppe
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- Rezaei Satar
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- Rezai Mohammad Sadegh
- Rezai Mohammad Sadegh
- Rokni Mohammad Bagher
- Rokni Mohammad Bagher
- Ronfani Luca
- Ronfani Luca
- Roshandel Gholamreza
- Roshandel Gholamreza
- Roth Gregory A
- Roth Gregory A
- Rothenbacher Dietrich
- Rothenbacher Dietrich
- Ruhago George Mugambage
- Ruhago George Mugambage
- SA Rizwan
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- Saadat Soheil
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- Sachdev Perminder S
- Sachdev Perminder S
- Sadat Nafis
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- Safdarian Mahdi
- Safdarian Mahdi
- Safi Sare
- Safi Sare
- Safiri Saeid
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- Sagar Rajesh
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- Sahathevan Ramesh
- Sahathevan Ramesh
- Salama Joseph
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- Salamati Payman
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- Salomon Joshua A
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- Samy Abdallah M
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- Santomauro Damian
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- Santos Itamar S
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- Santric Milicevic Milena M
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- Satpathy Maheswar
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- Schmidt Maria Inês
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- Schulhofer-Wohl Sam
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- Schutte Aletta E
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- Schwendicke Falk
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- Sepanlou Sadaf G
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- Servan-Mori Edson E
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- Shackelford Katya Anne
- Shackelford Katya Anne
- Shahraz Saeid
- Shahraz Saeid
- Shaikh Masood Ali
- Shaikh Masood Ali
- Shamsipour Mansour
- Shamsipour Mansour
- Shamsizadeh Morteza
- Shamsizadeh Morteza
- Sharma Jayendra
- Sharma Jayendra
- Sharma Rajesh
- Sharma Rajesh
- She Jun
- She Jun
- Sheikhbahaei Sara
- Sheikhbahaei Sara
- Shey Muki
- Shey Muki
- Shi Peilin
- Shi Peilin
- Shields Chloe
- Shields Chloe
- Shigematsu Mika
- Shigematsu Mika
- Shiri Rahman
- Shiri Rahman
- Shirude Shreya
- Shirude Shreya
- Shiue Ivy
- Shiue Ivy
- Shoman Haitham
- Shoman Haitham
- Shrime Mark G
- Shrime Mark G
- Sigfusdottir Inga Dora
- Sigfusdottir Inga Dora
- Silpakit Naris
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- Silva João Pedro
- Silva João Pedro
- Singh Abhishek
- Singh Abhishek
- Singh Jasvinder A
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- Skiadaresi Eirini
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- Sligar Amber
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- Smith Alison
- Smith Alison
- Smith David L
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- Smith Mari
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- Sobaih Badr HA
- Sobaih Badr HA
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- Sorensen Reed JD
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- Soriano Joan B
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- Sreeramareddy Chandrashekhar T
- Sreeramareddy Chandrashekhar T
- Srinivasan Vinay
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- Stanaway Jeffrey D
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- Stathopoulou Vasiliki
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- Swaminathan Soumya
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- Tabarés-Seisdedos Rafael
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- Tadakamadla Santosh Kumar
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- Takahashi Ken
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- Tarawneh Mohammed Rasoul
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- Thomas Katie E
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- Thompson Alex H
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- Yimam Hassen Hamid
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- Yonemoto Naohiro
- Yoon Seok-Jun
- Yoon Seok-Jun
- Yotebieng Marcel
- Yotebieng Marcel
- Younis Mustafa Z
- Younis Mustafa Z
- Zaidi Zoubida
- Zaidi Zoubida
- Zaki Maysaa El Sayed
- Zaki Maysaa El Sayed
- Zegeye Elias Asfaw
- Zegeye Elias Asfaw
- Zenebe Zerihun Menlkalew
- Zenebe Zerihun Menlkalew
- Zerfu Taddese Alemu
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- Zhang Anthony Lin
- Zhang Anthony Lin
- Zhang Xueying
- Zhang Xueying
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- Zodpey Sanjay
- Ärnlöv Johan
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2017
- Field of study
Background Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides a comprehensive assessment of cause-specific mortality for 264 causes in 195 locations from 1980 to 2016. This assessment includes evaluation of the expected epidemiological transition with changes in development and where local patterns deviate from these trends. Methods We estimated cause-specific deaths and years of life lost (YLLs) by age, sex, geography, and year. YLLs were calculated from the sum of each death multiplied by the standard life expectancy at each age. We used the GBD cause of death database composed of: vital registration (VR) data corrected for under-registration and garbage coding; national and subnational verbal autopsy (VA) studies corrected for garbage coding; and other sources including surveys and surveillance systems for specific causes such as maternal mortality. To facilitate assessment of quality, we reported on the fraction of deaths assigned to GBD Level 1 or Level 2 causes that cannot be underlying causes of death (major garbage codes) by location and year. Based on completeness, garbage coding, cause list detail, and time periods covered, we provided an overall data quality rating for each location with scores ranging from 0 stars (worst) to 5 stars (best). We used robust statistical methods including the Cause of Death Ensemble model (CODEm) to generate estimates for each location, year, age, and sex. We assessed observed and expected levels and trends of cause-specific deaths in relation to the Socio-demographic Index (SDI), a summary indicator derived from measures of average income per capita, educational attainment, and total fertility, with locations grouped into quintiles by SDI. Relative to GBD 2015, we expanded the GBD cause hierarchy by 18 causes of death for GBD 2016. Findings The quality of available data varied by location. Data quality in 25 countries rated in the highest category (5 stars), while 48, 30, 21, and 44 countries were rated at each of the succeeding data quality levels. Vital registration or verbal autopsy data were not available in 27 countries, resulting in the assignment of a zero value for data quality. Deaths from non-communicable diseases (NCDs) represented 72.3% (95% uncertainty interval [UI] 71.2-73.2) of deaths in 2016 with 19.3% (18.5-20.4) of deaths in that year occurring from communicable, maternal, neonatal, and nutritional (CMNN) diseases and a further 8.43% (8.00-8.67) from injuries. Although age-standardised rates of death from NCDs decreased globally between 2006 and 2016, total numbers of these deaths increased; both numbers and age-standardised rates of death from CMNN causes decreased in the decade 2006-16-age-standardised rates of deaths from injuries decreased but total numbers varied little. In 2016, the three leading global causes of death in children under-5 were lower respiratory infections, neonatal preterm birth complications, and neonatal encephalopathy due to birth asphyxia and trauma, combined resulting in 1.80 million deaths (95% UI 1.59 million to 1.89 million). Between 1990 and 2016, a profound shift toward deaths at older ages occurred with a 178% (95% UI 176-181) increase in deaths in ages 90-94 years and a 210% (208-212) increase in deaths older than age 95 years. The ten leading causes by rates of age-standardised YLL significantly decreased from 2006 to 2016 (median annualised rate of change was a decrease of 2.89%); the median annualised rate of change for all other causes was lower (a decrease of 1.59%) during the same interval. Globally, the five leading causes of total YLLs in 2016 were cardiovascular diseases; diarrhoea, lower respiratory infections, and other common infectious diseases; neoplasms; neonatal disorders; and HIV/AIDS and tuberculosis. At a finer level of disaggregation within cause groupings, the ten leading causes of total YLLs in 2016 were ischaemic heart disease, cerebrovascular disease, lower respiratory infections, diarrhoeal diseases, road injuries, malaria, neonatal preterm birth complications, HIV/AIDS, chronic obstructive pulmonary disease, and neonatal encephalopathy due to birth asphyxia and trauma. Ischaemic heart disease was the leading cause of total YLLs in 113 countries for men and 97 countries for women. Comparisons of observed levels of YLLs by countries, relative to the level of YLLs expected on the basis of SDI alone, highlighted distinct regional patterns including the greater than expected level of YLLs from malaria and from HIV/AIDS across sub-Saharan Africa; diabetes mellitus, especially in Oceania; interpersonal violence, notably within Latin America and the Caribbean; and cardiomyopathy and myocarditis, particularly in eastern and central Europe. The level of YLLs from ischaemic heart disease was less than expected in 117 of 195 locations. Other leading causes of YLLs for which YLLs were notably lower than expected included neonatal preterm birth complications in many locations in both south Asia and southeast Asia, and cerebrovascular disease in western Europe. Interpretation The past 37 years have featured declining rates of communicable, maternal, neonatal, and nutritional diseases across all quintiles of SDI, with faster than expected gains for many locations relative to their SDI. A global shift towards deaths at older ages suggests success in reducing many causes of early death. YLLs have increased globally for causes such as diabetes mellitus or some neoplasms, and in some locations for causes such as drug use disorders, and conflict and terrorism. Increasing levels of YLLs might reflect outcomes from conditions that required high levels of care but for which effective treatments remain elusive, potentially increasing costs to health systems. Copyright (C) The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
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- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
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- Abed Saeed
- Abelló David
- Abiola Olajide
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- Abou El.soud Moustafa Ramadan
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- Abraham Joyner
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- Abu Ahammala Ayman B.
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- Misk Rami
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- Yilmaz Duygu
- Yip Ching Wan
- Ylatoma Díaz Edgar Alcides
- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
- Younes Eman
- Younes Maha
- Yousry Basant
- Yozgatli Tahir Koray
- Yu Kristin
- Yue Sum Yu Pansy
- Yunes Asmaa
- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
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- Alasttal Mohammed
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- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
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- Alimi Marjan
- Aliosin Oleg
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- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
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- Alser Osaid
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- Altaf Amna
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- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
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- Alwali Abdallah
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- Alzabti Fatima
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- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
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- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
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- Appukuttan Akhila
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- Archibald Jess
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- Athamneh Sarah
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- Baggaley Caitlin
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- Baiao José Miguel
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- Barrera López Francisco Javier
- Barsic Neven
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- Bartosiak Katarzyna
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- Basso Stefano Maria Massimiliano.
- Bastiaenen Vivian
- Batashki Ilia
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- Belal qadomi Asef
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- El-taweel Alaa
- Elazab Yasmin
- Elbarouni Sofian
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- Elbeshina Aya Elseed
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- Eldmaty Asmaa
- Eldoseuky mohammed Amany
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- Elewaily Mohamed Ibrahim Elsayed
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- Elrais Safa
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- Elsayed Mohammad
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- Elshaibani Mahmoud
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- Elshawy Mohamed Elemam
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- Esposito Giovanni
- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
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- Fairfield Cameron J
- Falato Armando
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- M R Rashmi
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- Ma Yanru
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- Manatakis Dimitrios K.
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- Nsengiyumva Carlos
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- Obaid Mohammed
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- Ojewola Rufus Wale
- Okalany Noella
- Olajide Thomas Olagboyega
- Olaogun Julius
- Olasehinde Olalekan
- Olazo Espejo Dennet Arturo
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- Sánchez-García Jorge
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- V Sushmita
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- van Berge Henegouwen Mark
- van Berge Henegouwen Mark I.
- van Dalen Anne Sophie
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- Van hentenryck Marie
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- Vaska Ashish I
- Vaughan-Shaw Peter G
- Vaysse Charlotte
- Vazquez Fernandez Andrea
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- Warden Claire
- Warren Craig Russell
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- Warwicker Sean
- Wason Deepender
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- Watts Daniel
- Weiser Thomas G
- Welch Matthew
- Wellington Jack
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- Whitaker John
- White Rebecca
- Wiberg Rebecca
- Widmer Lukas Werner
- Wierdak Mateusz
- Wijekoon Arachchilage Nimeshi
- Wilguens Lartigue Jean
- Willemin Melissa
- Williams Christopher Yee Khang
- Wills Vanessa
- Wilson Karim
- Wilson Michael
- Wimmer Kerstin
- Windsor John
- Wineberg Devorah
- Winiarski Marek
- Winoto Hadi
- Winter Beatty Jasmine
- Winter Des
- Wisal Maham
- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
- Wong Lai Fen
- Wong Michael Pak-Kai
- Wong Sui-Weng
- Wong Tsz Lun Ernest
- Wood Lauren
- Woon-Shoo-Tong Xiao-Ming Sarah
- Wren Sherry
- Wuraola Funmilola
- Xanthopoulou Georgia
- Yabut Kenneth
- Yacoub Aseel
- Yaghi Nadine
- Yaghi Yasmine
- Yahia Mohamed Ali Mohamed
- Yakushkina Al'ona
- Yalçinkaya Ali
- Yang P Zichu
- Yanikoğlu Erkan
- Yanni Fady
- Yates Charlotte
- Ye Geoffrey
- Yeen Chin Leow
- Yemez Kürşat
- Yenidünya Nilüfer
- Yenli Edwin
- Yeo Jeremy
- Yeoh Andrea
- Yepez Raul
- Yeşilsancak Merve
- Yildirim Reyyan
- Yildiz Alp
- Yilmaz Duygu
- Yip Ching Wan
- Ylatoma Díaz Edgar Alcides
- Yong Shun Qi
- Yoong Andrel
- Yorke Joseph
- Yotsov Tsanko
- You Lucia
- Younes Eman
- Younes Maha
- Yousry Basant
- Yozgatli Tahir Koray
- Yu Kristin
- Yue Sum Yu Pansy
- Yunes Asmaa
- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati Cristiana
- Abbas Kaja M.
- Abbasi Mohammad
- Abbasi-Kangevari Mohsen
- Abbasifard Mitra
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- Mohammad Yousef
- Mohammadbeigi Abolfazl
- Mohammadian-Hafshejani Abdollah
- Mohammadifard Noushin
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- Moradi-Lakeh Maziar
- Moradzadeh Rahmatollah
- Moraga Paula
- Morales Linda
- Morawska Lidia
- Morgado-da-Costa Joana
- Morrison Shane Douglas
- Mosapour Abbas
- Mosser Jonathan F.
- Motlagh Soraya Nouraei
- Mouodi Simin
- Mousavi Seyyed Meysam
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- Mukhopadhyay Satinath
- Mullany Erin C.
- Mumford John Everett
- Munro Sandra B.
- Muriithi Moses K.
- Murray Christopher J. L.
- Musa Kamarul Imran
- Mustafa Ghulam
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- Nabavizadeh Behnam
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- Nagaraja Sharath Burugina
- Nagarajan Ahamarshan Jayaraman
- Nagel Gabriele
- Naghavi Mohsen
- Naghshtabrizi Behshad
- Naik Gurudatta
- Naimzada Mukhammad David
- Nair Sanjeev
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- Naldi Luigi
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- Nasab Entezar Mehrabi
- Naserbakht Morteza
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- Ngari Kiirithio N.
- Nguefack-Tsague Georges
- Ngunjiri Josephine W.
- Nguyen Cuong Tat
- Nguyen Diep Ngoc
- Nguyen Huong Lan Thi
- Nguyen Jason
- Nguyen Michele
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- Nguyen Trang Huyen
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- Nowak Christoph
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- Nunez-Samudio Virginia
- Oancea Bogdan
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- Ogbo Felix Akpojene
- Oghenetega Onome Bright
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- Okunga Emmanuel Wandera
- Oladnabi Morteza
- Olagunju Andrew T.
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Oluwasanu Mojisola Morenike
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- Otstavnov Nikita
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- Overland Simon
- Owolabi Mayowa O.
- Padubidri Jagadish Rao
- Pakhale Smita
- Pakhare Abhijit P.
- Pakshir Keyvan
- Palladino Raffaele
- Pana Adrian
- Panda-Jonas Songhomitra
- Pandey Anamika
- Pangaribuan Helena Ullyartha
- Park Eun-Kee
- Park James
- Parmar Priya G. Kumari
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- Pasovic Maja
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- Patel Jenil R.
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- Pathak Ashish
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- Patton George C.
- Paudel Deepak
- Paudel Sagun
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- Pease Spencer A.
- Peden Amy E.
- Pennini Alyssa
- Pepito Veincent Christian Filipino
- Peprah Emmanuel K.
- Pereira Alexandre
- Pereira David M.
- Pereira Jeevan
- Perico Norberto
- Pescarini Julia Moreira
- Pesudovs Konrad
- Pham Hai Quang
- Phillips Michael R.
- Piccinelli Cristiano
- Pierce Maxwell
- Pigott David M.
- Pilgrim Thomas
- Pilz Tessa M.
- Pinheiro Marina
- Piradov Michael A.
- Pirsaheb Meghdad
- Pishgar Farhad
- Plana-Ripoll Oleguer
- Plass Dietrich
- Pletcher Martin
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- Polibin Roman V.
- Polinder Suzanne
- Polkinghorne Kevan R.
- Pond Constance Dimity
- Postma Maarten J.
- Pottoo Faheem Hyder
- Pourjafar Hadi
- Pourmalek Farshad
- Pourshams Akram
- Poznanska Anna
- Prada Sergio I.
- Prakash Sanjay
- Prakash V.
- Prasad Narayan
- Preotescu Liliana
- Pribadi Dimas Ria Angga
- Pupillo Elisabetta
- Quazi Syed Zahiruddin
- Quintanilla Beatriz Paulina Ayala
- Rabiee Mohammad
- Rabiee Navid
- Radfar Amir
- Rafiee Ata
- Rafiei Alireza
- Raggi Alberto
- Rahim Fakher
- Rahimi-Movaghar Afarin
- Rahman Mohammad Hifz Ur
- Rahman Muhammad Aziz
- Rajabpour-Sanati Ali
- Rajati Fatemeh
- Rakovac Ivo
- Ram Pradhum
- Ramezanzadeh Kiana
- Rana Saleem Muhammad
- Ranabhat Chhabi Lal
- Ranta Annemarei
- Rao Puja C.
- Rao Sowmya J.
- Rasella Davide
- Rashedi Vahid
- Rastogi Prateek
- Rath Goura Kishor
- Rathi Priya
- Rawaf David Laith
- Rawaf Salman
- Rawal Lal
- Rawassizadeh Reza
- Rawat Ramu
- Razo Christian
- Regassa Lemma Demissie
- Reiner Jr., Robert C.
- Reinig Nickolas
- Reitsma Marissa Bettay
- Remuzzi Giuseppe
- Renjith Vishnu
- Renzaho Andre M. N.
- Resnikoff Serge
- Rezaei Negar
- Rezaei Nima
- Rezai Mohammad Sadegh
- Rezapour Aziz
- Rhinehart Phoebe-Anne
- Riahi Seyed Mohammad
- Ribeiro Antonio Luiz P.
- Ribeiro Daniel Cury
- Ribeiro Daniela
- Rickard Jennifer
- Rincon Julio Cesar Campuzano
- Rivera Juan A.
- Robalik Toshana
- Roberts Nicholas L. S.
- Roberts Shaun
- Robinson Stephen R.
- Rodriguez-Ramirez Sonia
- Roever Leonardo
- Rolfe Sam
- Romoli Michele
- Ronfani Luca
- Room Robin
- Roshandel Gholamreza
- Rostamian Morteza
- Roth Gregory A.
- Rothenbacher Dietrich
- Rubagotti Enrico
- Rumisha Susan Fred
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- Sabour Siamak
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- Saddik Basema
- Sadeghi Ehsan
- Sadeghi Masoumeh
- Saeedi Reza
- Saeidi Shahram
- Safari Yahya
- Safi Sare
- Safiri Saeid
- Sagar Rajesh
- Sahebkar Amirhossein
- Sahraian Mohammad Ali
- Sajadi S. Mohammad
- Salahshoor Mohammad Reza
- Salam Nasir
- Salama Joseph S.
- Salamati Payman
- Salem Hosni
- Salem Marwa R.
- Salimi Yahya
- Salimzadeh Hamideh
- Salman Omar Mukhtar
- Salomon Joshua A.
- Salz Inbal
- Samad Zainab
- Sambala Evanson Zondani
- Samy Abdallah M.
- Sanabria Juan
- Sanchez-Pimienta Tania G.
- Santomauro Damian Francesco
- Santos Itamar S.
- Santos Joao Vasco
- Santric-Milicevic Milena M.
- Saraswathy Sivan Yegnanarayana Iyer
- Sarmiento-Suarez Rodrigo
- Sarrafzadegan Nizal
- Sartorius Benn
- Sarveazad Arash
- Sathian Brijesh
- Sathish Thirunavukkarasu
- Sattin Davide
- Savic Miloje
- Sawyer Susan M.
- Saxena Deepak
- Saxena Sonia
- Saylan Mete
- Sbarra Alyssa N.
- Schaeffer Lauren E.
- Schiavolin Silvia
- Schlaich Markus P.
- Schmidt Maria Ines
- Schutte Aletta Elisabeth
- Schwebel David C.
- Schwendicke Falk
- Section Mahesh P. A.
- Seedat Soraya
- Sekerija Mario
- Senbeta Anbissa Muleta
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- Sepanlou Sadaf G.
- Serdar Berrin
- Serre Marc L.
- Servan-Mori Edson
- Sha Feng
- Shabani Mahsima
- Shackelford Katya Anne
- Shadid Jamileh
- Shafaat Omid
- Shahabi Saeed
- Shahbaz Mohammad
- Shaheen Amira A.
- Shaikh Masood Ali
- Shaji K. S.
- Shalash Ali S.
- Shams-Beyranvand Mehran
- Shamsi MohammadBagher
- Shamsizadeh Morteza
- Shannawaz Mohammed
- Sharafi Kiomars
- Sharafi Zeinab
- Sharan Subodh
- Sharara Fablina
- Sharifi Hamid
- Sharma Rajesh
- Shaw David H.
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- Sheikh Aziz
- Sheikhtaheri Abbas
- Shetty B. Suresh Kumar
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- Shin Min-Jeong
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- Shuval Kerem
- Siabani Soraya
- Sierpinski Radoslaw
- Sigfusdottir Inga Dora
- Sigurvinsdottir Rannveig
- Silva Diego Augusto Santos
- Silva Joao Pedro
- Simonetti Biagio
- Simpson Kyle E.
- Singh Ambrish
- Singh Jasvinder A.
- Singh Pushpendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skou Soren T.
- Skryabin Valentin Yurievich
- Sliwa Karen
- Smith Amanda
- Smith Emma U. R.
- Sobngwi Eugene
- Soheili Amin
- Sokhan Anton
- Soltani Shahin
- Somefun Oluwaseyi Dolapo
- Soofi Moslem
- Sorensen Reed J. D.
- Soriano Joan B.
- Sorrie Muluken Bekele
- Soshnikov Sergey
- Soyiri Ireneous N.
- Spencer Cory N.
- Spotin Adel
- Spurlock Emma Elizabeth
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Sripada Kam
- Stanaway Jeffrey D.
- Stark Benjamin A.
- Steel Nicholas
- Stefan Simona Catalina
- Stein Caroline
- Stein Dan J.
- Steiner Caitlyn
- Steiner Timothy J.
- Steuben Krista M.
- Stockfelt Leo
- Stokes Mark A.
- Stovner Lars Jacob
- Straif Kurt
- Stranges Saverio
- Stubbs Jacob L.
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- Sudaryanto Agus
- Sufiyan Mu'awiyyah Babale
- Suleria Hafiz Ansar Rasul
- Sulo Gerhard
- Sultan Iyad
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- Szocska Miklos
- Szumowski Lukasz
- Tabares-Seisdedos Rafael
- Tabb Karen M.
- Tabuchi Takahiro
- Tadakamadla Santosh Kumar
- Taddele Biruk Wogayehu
- Tadesse Degena Bahrey
- Taherkhani Amir
- Tahir Zarfishan
- Tajdini Masih
- Takahashi Ken
- Takala Jukka S.
- Tamiru Animut Tagele
- Tang Muming
- Tanser Frank C.
- Tareque Md Ismail
- Tarigan Ingan Ukur
- Taveira Nuno
- Taylor Heather Jean
- Teagle Whitney L.
- Teame Hirut
- Tediosi Fabrizio
- Tefera Yonas Getaye
- Tehrani-Banihashemi Arash
- Teklehaimanot Berhane Fseha
- Tela Freweini Gebrearegay
- Temsah Mohamad-Hani
- Terrason Sonyah
- Tesema Getayeneh Antehunegn
- Tessema Zemenu Tadesse
- Thakur Bhaskar
- Thankappan Kavumpurathu Raman
- Thapar Rekha
- Thomas Nihal
- Thomson Azalea M.
- Thrift Amanda G.
- Thurston George D.
- Titova Mariya Vladimirovna
- Tlou Boikhutso
- Tohidinik Hamid Reza
- Tonelli Marcello
- Topor-Madry Roman
- Topouzis Fotis
- Toroudi Hamidreza Pazoki
- Torre Anna E.
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Traini Eugenio
- Tran Bach Xuan
- Travillian Ravensara
- Trias-Llimos Sergi
- Troeger Christopher E.
- Truelsen Thomas Clement
- Tsai Alexander C.
- Tsatsakis Aristidis
- Tyrovolas Stefanos
- Uddin Riaz
- Ullah Irfan
- Ullah Saif
- Umeokonkwo Chukwuma David
- Undurraga Eduardo A.
- Unnikrishnan Bhaskaran
- Upadhyay Era
- Uthman Olalekan A.
- Vacante Marco
- Vaicekonyte Regina
- Vakilian Alireza
- Valdez Pascual R.
- Valli Alessandro
- Van Donkelaar Aaron
- Vardavas Constantine
- Varughese Santosh
- Vasankari Tommi Juhani
- Vasconcelos Ana Maria Nogales
- Vasseghian Yasser
- Veisani Yousef
- Velasquez Ilais Moreno
- Venketasubramanian Narayanaswamy
- Vidale Simone
- Violante Francesco S.
- Vlassov Vasily
- Vollset Stein Emil
- Vongpradith Avina
- Vos Theo
- Vu Giang Thu
- Vujcic Isidora S.
- Vukovic Ana
- Vukovic Rade
- Waheed Yasir
- Wallin Mitchell Taylor
- Walters Magdalene K.
- Wamai Richard G.
- Wang Fang
- Wang Haidong
- Wang Hongbo
- Wang Jiayu
- Wang Yafeng
- Wang Yanzhong
- Wang Yuan-Pang
- Ward Joseph L.
- Watson Alexandrea
- Watson Stefanie
- Wei Jingkai
- Wei Melissa Y. Wei
- Weintraub Robert G.
- Weiss Daniel J.
- Weiss Jordan
- Welay Fissaha Tekulu
- Weldesamuel Girmay Teklay
- Werdecker Andrea
- West J. Jason
- Westerman Ronny
- Whisnant Joanna L.
- Whiteford Harvey A.
- Wiangkham Taweewat
- Wickramasinghe Nuwan Darshana
- Wiens Kirsten E.
- Wijeratne Tissa
- Wilner Lauren B.
- Wilson Shadrach
- Wiysonge Charles Shey
- Wojtyniak Bogdan
- Woldu Gebremariam
- Wolfe Charles D. A.
- Wondmeneh Temesgen Gebeyehu
- Wondmieneh Adam Belay
- Wool Eve E.
- Wozniak Sarah S.
- Wu Ai-Min
- Wu Chenkai
- Wu Junjie
- Wunrow Han Yong
- Xie Yang
- Xu Gelin
- Xu Rixing
- Yadgir Simon
- Yamada Tomohide
- Yamagishi Kazumasa
- Yaminfirooz Mousa
- Yano Yuichiro
- Yaya Sanni
- Yazdi-Feyzabadi Vahid
- Yearwood Jamal A.
- Yeheyis Tomas Y.
- Yeshitila Yordanos Gizachew
- Yilgwan Christopher Sabo
- Yilma Mekdes Tigistu
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- York Hunter W.
- Younis Mustafa Z.
- Younker Theodore Patrick
- Yousefi Bahman
- Yousefi Zabihollah
- Yousefifard Mahmoud
- Yousefinezhadi Taraneh
- Yousuf Abdilahi Yousuf
- Yu Chuanhua
- Yu Yong
- Yuan Chun-Wei
- Yuce Deniz
- Yusefzadeh Hasan
- Zadey Siddhesh
- Zahabi Saleh Salehi
- Zaidi Syed Saoud
- Zaki Leila
- Zaki Maysaa El Sayed
- Zakzuk Josefina
- Zamani Mohammad
- Zamanian Maryam
- Zandian Hamed
- Zangeneh Alireza
- Zarafshan Hadi
- Zastrozhin Mikhail Sergeevich
- Zewdie Kaleab Alemayehu
- Zhang Jianrong
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Jeff T.
- Zhao Xiu-Ju George
- Zhao Yingxi
- Zheleva Bistra
- Zheng Peng
- Zhou Maigeng
- Zhu Cong
- Ziapour Arash
- Zimsen Stephanie R. M.
- Zlavog Bianca S.
- Zodpey Sanjay
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study