Modeling of some pistachio drying characteristics in fix, semi fluid and fluid bed dryer

Modeling of pistachio (cv. Ohadi) drying kinetic was carried out in a thin layer dryer of fix, semi fluid and fluid bed. Initial moisture content of pistachio samples was about 50.3% (d.b.).  Three drying characteristics of effective diffusivity, energy of activation and specific energy consumption were computed and influences of drying parameters were investigated.  Air temperature levels of 45, 60, 75 and 90℃ and bed conditions of fix, semi fluid and fluid bed were applied in these experiments.  Six mathematical models were used to predict the moisture ratio of pistachio samples in thin layer drying. Results showed that the Two-term model had supremacy in prediction of pistachio drying behavior.  Effective moisture diffusivity of pistachio was calculated using Fick’s second law.  Maximum and minimum values of effective moisture diffusivity calculated between 8.60×10-9 m2/sand 1.98×10-9 m2/s, respectively.  The calculated values of energy of activation for pistachio samples were computed between 30.52 kJ/mol and 35.26 kJ/mol for temperature boundary of 45 to 90℃ and bed conditions of fix to fluid bed.  Specific consumption of energy in thin layer drying of pistachio varied between 0.531×106 and 1.447×106 kJ/kg. Increase in air temperature in each bed condition cause decrease inspecific consumption of energy.  These pistachio properties are necessary to design the dryer system and to adjust the dryer in the best point.Keywords: Two-term model, thin layer drying, pistachio, diffusivity, energy&nbsp

Level of Moral Distress in Operating Room Technologist Students in Iran: A Cross‑Sectional Study

AbstractIntroduction: Moral distress is one of the issues considered in the educational environment. That it can affect the physical, psychological, and social dimensions of individuals and access to ethical and educational goals. This study aimed to investigate the moral distress in operating room technologist students of Iran University of Medical Sciences.Methods: This cross-sectional study was performed on Iran University of Medical Sciences' operating room technologist students in 2017. Data were collected with two questionnaires, including demographic information and a moral distress questionnaire. Data were analyzed by SPSS software using an independent t-test and one-way ANOVA (P < 0.05).Results: In this study, 121 operating room technologist students participated. The mean score of moral distress in the scores' severity and frequency dimensions was (3.5 ± 1.76) and (3.11 ± 1.6), respectively. The results showed that only age and semester had a significant relationship with the total score of moral distress, and with increasing age and semester, students’ moral pain has decreased.Conclusions: This study's results indicated that the moral distress in operating room technologist students was moderate, which requires investigating the factors involved in creating moral distress and providing strategies and measures to reduce its adverse effects in the educational setting

Determinants of Weight Loss and Obesity Control Behaviors Among Women Based on the Pender’s Health Promotion Model

Background: Lifestyle changes, advertising, and access to high-calorie, low-value foods have led to an increase in the prevalence of obesity and overweight, and women are at greater risk in this regard. The aim of the present study was to identify the determinants of weight loss and obesity control behaviors based on Pender’s health promotion model (HPM) among women referring to the healthcare centers of Shahrekord, Iran. Methods: This descriptive-analytical study was performed on 500 women aged 18-49 years with a body mass index (BMI) ≥ 25 in 2019. The cluster sampling method was performed on the healthcare centers, and women were selected using simple random sampling. The data collection instrument included a researcher-made questionnaire, the reliability and validity of which were approved, and finally, data were analyzed using analytical tests in SPSS 22 and Stata14. Results: The mean (± standard deviation) of the women’s age was 34.33 ± 8.2 years. A total of 57.8% of women had no history of weight loss and obesity control behaviors. Variables such as age, education level, and marital status were statistically significantly related to weight loss and obesity control behaviors (P≤ 0.05). Moreover, the constructs of prior related behaviors, interpersonal influences, and commitment to a plan of action were among the predictors of weight loss and obesity control behaviors and predicted 6.6% of behavioral changes (R2: 6.6, P< 0.05). Conclusion: Overall, prior related behaviors, interpersonal influences, and commitment to a plan of action are predictors of weight loss and obesity control behaviors, and thus it is suggested to place more on these constructs while designing relevant health-promotion interventions

Quantity and Quality of Vision Using Tinted Filters in Patients with Low Vision Due to Diabetic Retinopathy.

[en] PURPOSE: To investigate the effect of tinted filters on visual acuity (VA), contrast sensitivity and patient satisfaction in diabetic retinopathy associated with low vision. METHODS: In a prospective study, 51 patients with diabetic retinopathy and low vision were assessed. We chose a simple random sampling method and used the patient's files for data collection. LogMAR notations were applied for assessing VA and a contrast sensitivity chart (CSV-1000) was employed for measuring contrast sensitivity. First, measurements were performed without tinted filters and then using them. Appropriate lenses were given to the patients for 2 days, and they were questioned about their satisfaction using them in different places. RESULTS: A total of 20 male and 31 female patients with mean age of 57.3 years participated in the study. With a 527 ± 10 nm filter, mean VA improved significantly (P ≤ 0.05). Using the 527 ± 10 nm and 511 ± 10 nm filters, mean contrast sensitivity was improved significantly at 3 and 6 cycles/degree frequencies (P < 0.05). The effect of other filters on VA and contrast sensitivity was not significant. Patient satisfaction rate was generally high. CONCLUSION: Tinted filters are able to rehabilitate low-vision patients due to diabetic retinopathy. The 527 ± 10 and 511 ± 10 nm wavelength filters improved contrast sensitivity and the 527 ± 10 nm filter improved VA to some extent. Further investigations are recommended to assess the effect of these filters in patients with other causes of low-vision

Non-invasive diagnostic tests for Helicobacter pylori infection

BACKGROUND: Helicobacter pylori (H pylori) infection has been implicated in a number of malignancies and non-malignant conditions including peptic ulcers, non-ulcer dyspepsia, recurrent peptic ulcer bleeding, unexplained iron deficiency anaemia, idiopathic thrombocytopaenia purpura, and colorectal adenomas. The confirmatory diagnosis of H pylori is by endoscopic biopsy, followed by histopathological examination using haemotoxylin and eosin (H & E) stain or special stains such as Giemsa stain and Warthin-Starry stain. Special stains are more accurate than H & E stain. There is significant uncertainty about the diagnostic accuracy of non-invasive tests for diagnosis of H pylori. OBJECTIVES: To compare the diagnostic accuracy of urea breath test, serology, and stool antigen test, used alone or in combination, for diagnosis of H pylori infection in symptomatic and asymptomatic people, so that eradication therapy for H pylori can be started. SEARCH METHODS: We searched MEDLINE, Embase, the Science Citation Index and the National Institute for Health Research Health Technology Assessment Database on 4 March 2016. We screened references in the included studies to identify additional studies. We also conducted citation searches of relevant studies, most recently on 4 December 2016. We did not restrict studies by language or publication status, or whether data were collected prospectively or retrospectively. SELECTION CRITERIA: We included diagnostic accuracy studies that evaluated at least one of the index tests (urea breath test using isotopes such as13C or14C, serology and stool antigen test) against the reference standard (histopathological examination using H & E stain, special stains or immunohistochemical stain) in people suspected of having H pylori infection. DATA COLLECTION AND ANALYSIS: Two review authors independently screened the references to identify relevant studies and independently extracted data. We assessed the methodological quality of studies using the QUADAS-2 tool. We performed meta-analysis by using the hierarchical summary receiver operating characteristic (HSROC) model to estimate and compare SROC curves. Where appropriate, we used bivariate or univariate logistic regression models to estimate summary sensitivities and specificities. MAIN RESULTS: We included 101 studies involving 11,003 participants, of which 5839 participants (53.1%) had H pylori infection. The prevalence of H pylori infection in the studies ranged from 15.2% to 94.7%, with a median prevalence of 53.7% (interquartile range 42.0% to 66.5%). Most of the studies (57%) included participants with dyspepsia and 53 studies excluded participants who recently had proton pump inhibitors or antibiotics.There was at least an unclear risk of bias or unclear applicability concern for each study.Of the 101 studies, 15 compared the accuracy of two index tests and two studies compared the accuracy of three index tests. Thirty-four studies (4242 participants) evaluated serology; 29 studies (2988 participants) evaluated stool antigen test; 34 studies (3139 participants) evaluated urea breath test-13C; 21 studies (1810 participants) evaluated urea breath test-14C; and two studies (127 participants) evaluated urea breath test but did not report the isotope used. The thresholds used to define test positivity and the staining techniques used for histopathological examination (reference standard) varied between studies. Due to sparse data for each threshold reported, it was not possible to identify the best threshold for each test.Using data from 99 studies in an indirect test comparison, there was statistical evidence of a difference in diagnostic accuracy between urea breath test-13C, urea breath test-14C, serology and stool antigen test (P = 0.024). The diagnostic odds ratios for urea breath test-13C, urea breath test-14C, serology, and stool antigen test were 153 (95% confidence interval (CI) 73.7 to 316), 105 (95% CI 74.0 to 150), 47.4 (95% CI 25.5 to 88.1) and 45.1 (95% CI 24.2 to 84.1). The sensitivity (95% CI) estimated at a fixed specificity of 0.90 (median from studies across the four tests), was 0.94 (95% CI 0.89 to 0.97) for urea breath test-13C, 0.92 (95% CI 0.89 to 0.94) for urea breath test-14C, 0.84 (95% CI 0.74 to 0.91) for serology, and 0.83 (95% CI 0.73 to 0.90) for stool antigen test. This implies that on average, given a specificity of 0.90 and prevalence of 53.7% (median specificity and prevalence in the studies), out of 1000 people tested for H pylori infection, there will be 46 false positives (people without H pylori infection who will be diagnosed as having H pylori infection). In this hypothetical cohort, urea breath test-13C, urea breath test-14C, serology, and stool antigen test will give 30 (95% CI 15 to 58), 42 (95% CI 30 to 58), 86 (95% CI 50 to 140), and 89 (95% CI 52 to 146) false negatives respectively (people with H pylori infection for whom the diagnosis of H pylori will be missed).Direct comparisons were based on few head-to-head studies. The ratios of diagnostic odds ratios (DORs) were 0.68 (95% CI 0.12 to 3.70; P = 0.56) for urea breath test-13C versus serology (seven studies), and 0.88 (95% CI 0.14 to 5.56; P = 0.84) for urea breath test-13C versus stool antigen test (seven studies). The 95% CIs of these estimates overlap with those of the ratios of DORs from the indirect comparison. Data were limited or unavailable for meta-analysis of other direct comparisons. AUTHORS' CONCLUSIONS: In people without a history of gastrectomy and those who have not recently had antibiotics or proton ,pump inhibitors, urea breath tests had high diagnostic accuracy while serology and stool antigen tests were less accurate for diagnosis of Helicobacter pylori infection.This is based on an indirect test comparison (with potential for bias due to confounding), as evidence from direct comparisons was limited or unavailable. The thresholds used for these tests were highly variable and we were unable to identify specific thresholds that might be useful in clinical practice.We need further comparative studies of high methodological quality to obtain more reliable evidence of relative accuracy between the tests. Such studies should be conducted prospectively in a representative spectrum of participants and clearly reported to ensure low risk of bias. Most importantly, studies should prespecify and clearly report thresholds used, and should avoid inappropriate exclusions

Regulation of nitrogen fixation in rhizobia-legume symbioses

Rhizobia are soil-dwelling bacteria capable of infecting legume roots and forming a symbiotic association. Inside root nodules, low O2 levels trigger expression of the nitrogenase enzyme complex in rhizobia, allowing them to fix atmospheric N2 into NH3, and secrete this reduced nitrogen source to the host plant. Rhizobial N2 fixation is activated via the transcriptional regulator NifA, which is itself induced by low O2 concentration in legume root nodules, most commonly via the two-component sensor-regulator FixLJ or a modified version of this regulon. For rhizobia in the genus Mesorhizobium, it is currently unclear how low O2 tension is sensed and transduced into a signal to activate N2 fixation, with the FixLJ system shown to be dispensable for N2 fixation. Mesorhizobium ciceri CC1192, which forms a symbiosis with Cicer arietinum (chickpea) and is the commercial inoculant for this crop legume in Australia, harbours fixV, a putative LacI/GalR transcriptional regulator which may directly control the expression of nifA in this strain. To investigate the role of fixV and nifA within CC1192, inactivation vectors were constructed in the suicide vector pJQ200SK via Gibson Assembly and fixV and nifA deletion mutants generated, along with a nitrogenase null mutant (nifH) as a non-N2-fixing control. nifH mutants were symbiotically defective on C. arietinum, with nitrogenase activity completely abolished. Deletion of fixV resulted in reduced, but not abolished, nitrogenase activity on a per nodule basis and reduced foliage dry weights, while the ΔnifA mutant phenotype remains to be tested. FixV, therefore, is not essential for N2 fixation in CC1192 but likely plays a vital role alongside another as yet unidentified regulator

Investigating the role of mobile health in epilepsy management: A systematic review

Epilepsy is the most common chronic neurologic disease which is characterized by recurrent attacks of headache after seizure. Researches show that self-management is an important factor in improving the quality of life and quality of care of people affected by epilepsy. Mobile phone technologies play a potential role in patient care assistance and treatment of epilepsy. This systematic review was conducted with an aim to study the role of mobile health in the management of epilepsy. This study was conducted by searching databases such as PubMed, Scopus, Web of Science, and Google scholar search engines using the following keywords: “m-health,” “mobile health,” “Telemedicine,” “Mobile Application,” “Smartphone,” “epilepsy,” and “epilepsy management.” Articles published from January 1, 1990 to September 1, 2021 were searched. Inclusion criteria included all articles published in English with a focus on the role of mHealth in the management of epilepsy. Review articles and studies that were not about patients were omitted. In this study, of a total of 4225 retrieved articles, 10 studies met the full-text inclusion criteria. Three types of researches (30%) were done in the USA, five studies (50%) were conducted as randomized controlled trials, and eight articles (80%) had the highest quality. Among the considered articles, three articles (30%) were engaged in training users in epilepsy management. Five articles (50%) reported improvement in seizure control in patients with epilepsy and two articles (20%) did not report any significant improvement. Mobile technologies have a promising role in providing health assessment, education, and other services for patients, and they also help in controlling seizures attack and improvement of epilepsy management. These technologies enjoy great attractiveness, and utilizing them will lead to patient satisfaction