Inclusive production of X→bbˉ\rightarrow b\bar{b} plus a recoil for the LHC Run-II

This letter presents a study of the inclusive production of X$\rightarrow b\bar{b}$ plus a recoil, using simulated samples of $pp$ collisions at $\sqrt{s}=14$ TeV for an integrated luminosity in the range between 30 fb$^{-1}$ to 3 ab$^{-1}$. The case for experiments to include un-prescaled $b$-tag multijet triggers for this topology is made and the ideal jet thresholds are discussed. The sensitivity to Standard Model Higgs with a transverse momentum of at least 200 GeV is evaluated with respect to a continuous background, dominated by multijet processes. The mass of $b$-jet-pairs is analysed, quoting sensitivity to cross-sections in the range of 1 to 2 pb, for 100 fb$^{-1}$, covering the Higgs production cross section of 1.8 pb. The trigger strategy presented in this letter is compared to triggers already in use, showing an increase on the signal efficiency for masses below 200 GeV and a performance comparable to a logic OR of all the currently available akin triggers for higher masses. The robustness of the expected sensitivity against systematic uncertainties is estimated by considering various typical sources, such as those on the fitting parameters of the continuous background, shape uncertainties affecting the signal acceptance and the background modelling. The accuracy of a Higgs production cross section measurements is also discussed, quoting sensitivity to deviations of 50% for 100 fb$^{-1}$ and 10% for 3 ab$^{-1}$.Comment: 6 pages, 7 figure

A synthetic biology approach for consistent production of plant-made recombinant polyclonal antibodies against snake venom toxins

Antivenoms developed from the plasma of hyperimmunized animals are the only effective treatment available against snakebite envenomation but shortage of supply contributes to the high morbidity and mortality toll of this tropical disease. We describe a synthetic biology approach to affordable and cost-effective antivenom production based on plant-made recombinant polyclonal antibodies (termed pluribodies). The strategy takes advantage of virus superinfection exclusion to induce the formation of somatic expression mosaics in agroinfiltrated plants, which enables the expression of complex antibody repertoires in a highly reproducible manner. Pluribodies developed using toxin-binding genetic information captured from peripheral blood lymphocytes of hyperimmunized camels recapitulated the overall binding activity of the immune response. Furthermore, an improved plant-made antivenom (plantivenom) was formulated using an in vitro selected pluribody against Bothrops asper snake venom toxins and has been shown to neutralize a wide range of toxin activities and provide protection against lethal venom doses in mice.Fil: Julve Parreño, Jose Manuel. Universidad Politécnica de Valencia; EspañaFil: Huet, Estefanía. Universidad Politécnica de Valencia; EspañaFil: Fernández del Carmen, Asun. Universidad Politécnica de Valencia; EspañaFil: Segura, Alvaro. Universidad de Costa Rica; Costa RicaFil: Venturi, Micol. Universidad Politécnica de Valencia; EspañaFil: Gandía, Antoni. Universidad Politécnica de Valencia; EspañaFil: Pan, Wei-Song. Universidad Politécnica de Valencia; EspañaFil: Albaladejo, Irene. Universidad Politécnica de Valencia; EspañaFil: Forment, Javier. Universidad Politécnica de Valencia; EspañaFil: Pla, Davinia. Instituto de Biomedicina de Valencia; EspañaFil: Wigdorovitz, Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Genética; ArgentinaFil: Calvete, Juan J.. Instituto de Biomedicina de Valencia; EspañaFil: Gutiérrez, Carlos. Universidad de Las Palmas de Gran Canaria; EspañaFil: Gutiérrez, José María. Universidad de Costa Rica; Costa RicaFil: Granell, Antonio. Universidad Politécnica de Valencia; EspañaFil: Orzáez, Diego. Universidad Politécnica de Valencia; Españ

International Environmental Justice on Hold: Revisiting the Basel Ban from a Philippine Perspective

Nineteen years after the Basel Ban was adopted it still has not garnered the necessary ratifications to enter into force. This article aims to revisit the Basel Ban and understand it from the perspective of a developing country, particularly the Philippines, and draw out possible obstacles it faces in ratifying this instrument of international environmental justice. In addition the article will review the major issues raised by those opposed to the Basel Ban and verify if these concerns raised nineteen years ago still hold true today. This article has four main sections. The first section of this article briefly looks at the roots of international environmental justice in domestic environmental justice. The second section reviews the rise of toxic waste trade in the 1980s and the eventual rise of the Basel Convention and the Basel Ban. The article delves into the framework of the Basel Convention and the Basel Ban, their weaknesses and the elements of environmental justice found in both instruments. The third part of the article examines the current landscape of the Basel Ban from the perspective of a developing country, the Philippines. The Philippines is similar to many developing countries, with its high incidence of poverty and its own experience with illegal toxic waste trade. The Philippine perspective is important because it was a party to the Basel Convention when the Basel Ban was adopted. Thus, it is one of the qualifying countries whose ratification is needed for the Basel Ban to enter into force. Moreover, the Philippines is often cited as a case where the Basel Ban could cause adverse impacts on the local recycling industry and in turn affect national development. In examining the Philippine context, the article focuses on the trade in used lead acid batteries (ULABs) and electronic waste (e-waste) and where the country derives these wastes for its recycling industry. The article will also examine the anti-trade arguments leveled against the Basel Ban and the agreements that the Philippines has entered into to see the precedents the government is following, if any. The last section of this article is the conclusion. What is critical at this point in the ongoing saga of the Basel Ban is for countries to reexamine the issues surrounding the Basel Ban, and see if the arguments of the past still hold true. Undoubtedly, the Basel Ban has firmly left its mark in international law. Whether it remains a paper tiger will depend on the perseverance of developing countries to fight for this principle at the international level and ratify the instrument, and its observance and implementation nationally at the domestic level

On Cr−C^r-closing for flows on 2-manifolds

For some full measure subset B of the set of iet's (i.e. interval exchange transformations) the following is satisfied: Let X be a $C^r$, $1\le r\le \infty$, vector field, with finitely many singularities, on a compact orientable surface M. Given a nontrivial recurrent point $p\in M$ of X, the holonomy map around p is semi-conjugate to an iet $E :[0,1) \to [0,1).$ If $E\in B$ then there exists a $C^r$ vector field Y, arbitrarily close to X, in the $C^r-$topology, such that Y has a closed trajectory passing through p.Comment: 7 pages, 1 figur