Understanding liquid-jet atomization cascades via vortex dynamics

Temporal instabilities of a planar liquid jet are studied using direct numerical simulation (DNS) of the incompressible Navier-Stokes equations with level-set (LS) and volume-of-fluid (VoF) surface tracking methods. $\lambda_2$ contours are used to relate the vortex dynamics to the surface dynamics at different stages of the jet breakup, namely, lobe formation, lobe perforation, ligament formation, stretching, and tearing. Three distinct breakup mechanisms are identified in the primary breakup, which are well categorized on the parameter space of gas Weber number ($We_g$) versus liquid Reynolds number ($Re_l$). These mechanisms are analyzed here from a vortex dynamics perspective. Vortex dynamics explains the hairpin formation, and the interaction between the hairpins and the Kelvin-Helmholtz (KH) roller explains the perforation of the lobes, which is attributed to the streamwise overlapping of two oppositely-oriented hairpin vortices on top and bottom of the lobe. The formation of corrugations on the lobe front edge at high $Re_l$ is also related to the location and structure of the hairpins with respect to the KH vortex. The lobe perforation and corrugation formation are inhibited at low $Re_l$ and low $We_g$ due to the high surface tension and viscous forces, which damp the small scale corrugations and resist hole formation. Streamwise vorticity generation - resulting in three-dimensional instabilities - is mainly caused by vortex stretching and baroclinic torque at high and low density ratios, respectively. Generation of streamwise vortices and their interaction with spanwise vortices produce the liquid structures seen at various flow conditions. Understanding the liquid sheet breakup and the related vortex dynamics are crucial for controlling the droplet size distribution in primary atomization.Comment: Submitted for publication in Journal of Fluid Mechanics. 56 pages; 52 figure

Length-scale cascade and spread rate of atomizing planar liquid jets

The primary breakup of a planar liquid jet is explored via direct numerical simulation (DNS) of the incompressible Navier-Stokes equation with level-set and volume-of-fluid interface capturing methods. PDFs of the local radius of curvature and the local cross-flow displacement of the liquid-gas interface are evaluated over wide ranges of the Reynolds number ($Re$), Weber number ($We$), density ratio and viscosity ratio. The temporal cascade of liquid-structure length scales and the spread rate of the liquid jet during primary atomization are analyzed. The formation rate of different surface structures, e.g. lobes, ligaments and droplets, are compared for different flow conditions and are explained in terms of the vortex dynamics in each atomization domain that we identified recently. With increasing $We$, the average radius of curvature of the surface decreases, the number of small droplets increases, and the cascade and the surface area growth occur at faster rates. The spray angle is mainly affected by $Re$ and density ratio, and is larger at higher $We$, at higher density ratios, and also at lower $Re$. The change in the spray spread rate versus $Re$ is attributed to the angle of ligaments stretching from the jet core, which increases as $Re$ decreases. Gas viscosity has negligible effect on both the droplet-size distribution and the spray angle. Increasing the wavelength-to-sheet-thickness ratio, however, increases the spray angle and the structure cascade rate, while decreasing the droplet size. The smallest length scale is determined more by surface tension and liquid inertia than by the liquid viscosity, while gas inertia and liquid surface tension are the key parameters in determining the spray angle.Comment: Submitted for publication to International Journal of Multiphase Flow. 37 pages; 33 figure

Mechanisms of Liquid Stream Breakup: Vorticity and Time and Length Scales

[EN] The 3D, temporal instabilities on a planar liquid jet are studied using DNS with level-set and VoF interface-capturing methods. The λ2 method has been used to relate the vortex dynamics to the surface dynamics at different stages of the jet breakup. The breakup character depends on the Ohnesorge number (Oh) and gas-to-liquid density ratio. At high Reynolds number (Re) and high Oh, hairpin vortices form on the braid and overlap with the lobe hairpins, thinning the lobes, which then puncture creating holes and bridges. The bridges break, creating ligaments that stretch and break into droplets by capillary action. At low Oh and high Re, lobe stretching and thinning is hindered by high surface tension and splitting of the original Kelvin-Helmholtz vortex, preventing early hole formation. Corrugations form on the lobe edges, influenced by the split vortices, and stretch to form ligaments. Both mechanisms are present in a transitional region in the W e-Re map. At lower Re and not-too-large Weber number (W e), lobe stretching occurs but with longer and larger ligaments in this third domain which has a hyperbolic transition to the hole formation domain as W e increases. The three domains with differing breakup behaviors each occupy distinct portions of a plot of W e based on gas density versus Re based on liquid properties. Characteristic times for the hole formation, as well as the lobe and ligament stretching are different - the former depending on the surface tension and the latter on liquid viscosity. In the transitional region, both times are of the same order.Zandian, A.; Sirignano, W.; Hussain, F. (2017). Mechanisms of Liquid Stream Breakup: Vorticity and Time and Length Scales. En Ilass Europe. 28th european conference on Liquid Atomization and Spray Systems. Editorial Universitat Politècnica de València. 362-367. https://doi.org/10.4995/ILASS2017.2017.4616OCS36236

Dynamics of a spatially developing liquid jet with slower coaxial gas flow

A three-dimensional round liquid jet within a low-speed coaxial gas flow is numerically simulated and explained via vortex dynamics ($\lambda_2$ method). The instabilities on the liquid-gas interface reflect well the vortex interactions around the interface. Certain key features are identified for the first time. Two types of surface deformations are distinguished, which are separated by a large indentation on the jet stem: First, those near the jet start-up cap are encapsulated inside the recirculation zone behind the cap. These deformations are directly related to the dynamics of the growing cap and well explained by the vortices generated there. Second, deformations occurring farther upstream of the cap are mainly driven by the Kelvin-Helmholtz (KH) instability at the interface. Three-dimensional deformations occur in the vortex structures first, and the initially axisymmetric KH vortices deform and lead to several liquid lobes, which stretch first as thinning sheets and then either continue stretching directly into elongated ligaments - at lower relative velocity - or perforate to create liquid bridges and holes - at higher relative velocity. The different scenarios depend on Weber and Reynolds numbers based on the relative gas-liquid velocity as was found in the temporal studies. The deformations in the upstream region are well portrayed in a frame moving with the convective velocity of the liquid jet. The usefulness of the temporal analyses are now established.Comment: Presented at ICLASS 2018 conference; 8 pages; 19 Figure

Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations

Estimating global injuries morbidity and mortality : methods and data used in the Global Burden of Disease 2017 study

Background While there is a long history of measuring death and disability from injuries, modern research methods must account for the wide spectrum of disability that can occur in an injury, and must provide estimates with sufficient demographic, geographical and temporal detail to be useful for policy makers. The Global Burden of Disease (GBD) 2017 study used methods to provide highly detailed estimates of global injury burden that meet these criteria. Methods In this study, we report and discuss the methods used in GBD 2017 for injury morbidity and mortality burden estimation. In summary, these methods included estimating cause-specific mortality for every cause of injury, and then estimating incidence for every cause of injury. Non-fatal disability for each cause is then calculated based on the probabilities of suffering from different types of bodily injury experienced. Results GBD 2017 produced morbidity and mortality estimates for 38 causes of injury. Estimates were produced in terms of incidence, prevalence, years lived with disability, cause-specific mortality, years of life lost and disability-adjusted life-years for a 28-year period for 22 age groups, 195 countries and both sexes. Conclusions GBD 2017 demonstrated a complex and sophisticated series of analytical steps using the largest known database of morbidity and mortality data on injuries. GBD 2017 results should be used to help inform injury prevention policy making and resource allocation. We also identify important avenues for improving injury burden estimation in the future.Peer reviewe

Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-Adjusted life-years for 29 cancer groups, 1990 to 2017 : A systematic analysis for the global burden of disease study

Importance: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data. Objective: To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning. Evidence Review: We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-Adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence. Findings: In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs for men were TBL cancer (1.3 million deaths and 28.4 million DALYs), liver cancer (572000 deaths and 15.2 million DALYs), and stomach cancer (542000 deaths and 12.2 million DALYs). For women in 2017, the most common incident cancers were NMSC (3.3 million incident cases), breast cancer (1.9 million incident cases), and colorectal cancer (819000 incident cases). The leading causes of cancer deaths and DALYs for women were breast cancer (601000 deaths and 17.4 million DALYs), TBL cancer (596000 deaths and 12.6 million DALYs), and colorectal cancer (414000 deaths and 8.3 million DALYs). Conclusions and Relevance: The national epidemiological profiles of cancer burden in the GBD study show large heterogeneities, which are a reflection of different exposures to risk factors, economic settings, lifestyles, and access to care and screening. The GBD study can be used by policy makers and other stakeholders to develop and improve national and local cancer control in order to achieve the global targets and improve equity in cancer care. © 2019 American Medical Association. All rights reserved.Peer reviewe

Global injury morbidity and mortality from 1990 to 2017 : results from the Global Burden of Disease Study 2017

Correction:Background Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. Methods We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). Findings In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505). Interpretation Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care.Peer reviewe

The global burden of adolescent and young adult cancer in 2019 : a systematic analysis for the Global Burden of Disease Study 2019

Background In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15-39 years to define adolescents and young adults. Findings There were 1.19 million (95% UI 1.11-1.28) incident cancer cases and 396 000 (370 000-425 000) deaths due to cancer among people aged 15-39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59.6 [54.5-65.7] per 100 000 person-years) and high-middle SDI countries (53.2 [48.8-57.9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14.2 [12.9-15.6] per 100 000 person-years) and middle SDI (13.6 [12.6-14.8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23.5 million (21.9-25.2) DALYs to the global burden of disease, of which 2.7% (1.9-3.6) came from YLDs and 97.3% (96.4-98.1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe