180 research outputs found
Dynamics of a Limit Cycle Oscillator under Time Delayed Linear and Nonlinear Feedbacks
We study the effects of time delayed linear and nonlinear feedbacks on the
dynamics of a single Hopf bifurcation oscillator. Our numerical and analytic
investigations reveal a host of complex temporal phenomena such as phase slips,
frequency suppression, multiple periodic states and chaos. Such phenomena are
frequently observed in the collective behavior of a large number of coupled
limit cycle oscillators. Our time delayed feedback model offers a simple
paradigm for obtaining and investigating these temporal states in a single
oscillator.We construct a detailed bifurcation diagram of the oscillator as a
function of the time delay parameter and the driving strengths of the feedback
terms. We find some new states in the presence of the quadratic nonlinear
feedback term with interesting characteristics like birhythmicity, phase
reversals, radial trapping, phase jumps and spiraling patterns in the amplitude
space. Our results may find useful applications in physical, chemical or
biological systems.Comment: VERSION 4: Fig. 10(d) added, an uncited reference removed; (To appear
in Physica D) (17 pages, 21 figures, two column, aps RevTeX); VERSION 3:
Revised. In Section 2, small tau approximation added; Section 3 is divided
into subsections; periodic solution discussed in detail; Figs. 7 and 11
discarded; Figs. 12 and 14 altered; three new figures (now Figs. 10, 11 and
21) added. VERSION 2: Figs. 1 and 2 replace
Time Delay Effects on Coupled Limit Cycle Oscillators at Hopf Bifurcation
We present a detailed study of the effect of time delay on the collective
dynamics of coupled limit cycle oscillators at Hopf bifurcation. For a simple
model consisting of just two oscillators with a time delayed coupling, the
bifurcation diagram obtained by numerical and analytical solutions shows
significant changes in the stability boundaries of the amplitude death, phase
locked and incoherent regions. A novel result is the occurrence of amplitude
death even in the absence of a frequency mismatch between the two oscillators.
Similar results are obtained for an array of N oscillators with a delayed mean
field coupling and the regions of such amplitude death in the parameter space
of the coupling strength and time delay are quantified. Some general analytic
results for the N tending to infinity (thermodynamic) limit are also obtained
and the implications of the time delay effects for physical applications are
discussed.Comment: 20 aps formatted revtex pages (including 13 PS figures); Minor
changes over the previous version; To be published in Physica
Signatures of Supernova Neutrino Oscillations into Extra Dimensions
We consider the mixing of muon and tau neutrinos with sterile fermion fields
propagating in extra dimensions in the context of core collapse supernova
physics, extending the analysis of the electron neutrino case done in a
previous work. We show that the potentially dramatic modifications to the
supernova evolution are prevented by a mechanism of feedback, so that no severe
bounds on the parameters of the extra dimensions need to be imposed.
Nevertheless, the supernova core evolution is significantly modified. We
discuss the consequences on the delayed explosion mechanism and the
compatibility with the SN1987A signal. Then, for the cases of both nu_{mu,tau}
and nu_e mixing with bulk fermions, we analyse the distinctive features of the
signal on Earth.Comment: 16 pages, 7 figures; v2: minor changes, matches published versio
Chlorophyll and carbohydrates in Arachis pintoi plants under influence of water regimes and nitrogen fertilization
Non-local rheology in dense granular flows -- Revisiting the concept of fluidity
Granular materials belong to the class of amorphous athermal systems, like foams, emulsion or suspension they can resist shear like a solid, but flow like a liquid under a sufficiently large applied shear stress. They exhibit a dynamical phase transition between static and flowing states, as for phase transitions of thermodynamic systems, this rigidity transition exhibits a diverging length scales quantifying the degree of cooperatively. Several experiments have shown that the rheology of granular materials and emulsion is non-local, namely that the stress at a given location does not depend only on the shear rate at this location but also on the degree of mobility in the surrounding region. Several constitutive relations have recently been proposed and tested successfully against numerical and experimental results. Here we use discrete elements simulation of 2D shear flows to shed light on the dynamical mechanism underlying non-locality in dense granular flows
Observations of the High Redshift Universe
(Abridged) In these lectures aimed for non-specialists, I review progress in
understanding how galaxies form and evolve. Both the star formation history and
assembly of stellar mass can be empirically traced from redshifts z~6 to the
present, but how the various distant populations inter-relate and how stellar
assembly is regulated by feedback and environmental processes remains unclear.
I also discuss how these studies are being extended to locate and characterize
the earlier sources beyond z~6. Did early star-forming galaxies contribute
significantly to the reionization process and over what period did this occur?
Neither theory nor observations are well-developed in this frontier topic but
the first results presented here provide important guidance on how we will use
more powerful future facilities.Comment: To appear in `First Light in Universe', Saas-Fee Advanced Course 36,
Swiss Soc. Astrophys. Astron. in press. 115 pages, 64 figures (see
http://www.astro.caltech.edu/~rse/saas-fee.pdf for hi-res figs.) For lecture
ppt files see
http://obswww.unige.ch/saas-fee/preannouncement/course_pres/overview_f.htm
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015
Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context.
Methods: We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors—the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI).
Findings: Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57·8% (95% CI 56·6–58·8) of global deaths and 41·2% (39·8–42·8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211·8 million [192·7 million to 231·1 million] global DALYs), smoking (148·6 million [134·2 million to 163·1 million]), high fasting plasma glucose (143·1 million [125·1 million to 163·5 million]), high BMI (120·1 million [83·8 million to 158·4 million]), childhood undernutrition (113·3 million [103·9 million to 123·4 million]), ambient particulate matter (103·1 million [90·8 million to 115·1 million]), high total cholesterol (88·7 million [74·6 million to 105·7 million]), household air pollution (85·6 million [66·7 million to 106·1 million]), alcohol use (85·0 million [77·2 million to 93·0 million]), and diets high in sodium (83·0 million [49·3 million to 127·5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa.
Interpretation: Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden.
Funding: Bill & Melinda Gates Foundation
Researching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design
Importance Pregnancy induces unique physiologic changes to the immune response and hormonal changes leading to plausible differences in the risk of developing post-acute sequelae of SARS-CoV-2 (PASC), or Long COVID. Exposure to SARS-CoV-2 during pregnancy may also have long-term ramifications for exposed offspring, and it is critical to evaluate the health outcomes of exposed children. The National Institutes of Health (NIH) Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC aims to evaluate the long-term sequelae of SARS-CoV-2 infection in various populations. RECOVER-Pregnancy was designed specifically to address long-term outcomes in maternal-child dyads. Methods RECOVER-Pregnancy cohort is a combined prospective and retrospective cohort that proposes to enroll 2,300 individuals with a pregnancy during the COVID-19 pandemic and their offspring exposed and unexposed in utero, including single and multiple gestations. Enrollment will occur both in person at 27 sites through the Eunice Kennedy Shriver National Institutes of Health Maternal-Fetal Medicine Units Network and remotely through national recruitment by the study team at the University of California San Francisco (UCSF). Adults with and without SARS-CoV-2 infection during pregnancy are eligible for enrollment in the pregnancy cohort and will follow the protocol for RECOVER-Adult including validated screening tools, laboratory analyses and symptom questionnaires followed by more in-depth phenotyping of PASC on a subset of the overall cohort. Offspring exposed and unexposed in utero to SARS-CoV-2 maternal infection will undergo screening tests for neurodevelopment and other health outcomes at 12, 18, 24, 36 and 48 months of age. Blood specimens will be collected at 24 months of age for SARS-CoV-2 antibody testing, storage and anticipated later analyses proposed by RECOVER and other investigators. Discussion RECOVER-Pregnancy will address whether having SARS-CoV-2 during pregnancy modifies the risk factors, prevalence, and phenotype of PASC. The pregnancy cohort will also establish whether there are increased risks of adverse long-term outcomes among children exposed in utero
Determinação do sistema endócrino difuso nos intestinos de três Teleostei (Pisces) de água doce com hábitos alimentares diferentes
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