9 research outputs found
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- Abellán AN
- Abellán AN
- Abellán AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
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- Affatato R
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- Aguilar-Alonso E
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- Ahmadnia E
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- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
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- Ko JI
- Ko SB
- Kobayashi A
- Koco E
- Kodate A
- Kodate A
- Kodate A
- Kokkini S
- Kolnikova I
- Komuro T
- Kondili E
- Kongpolprom N
- Kooner G
- Kostalas M
- Kosuk ME
- Kotsopoulos A
- Kou PS
- Kouatchet A
- Kovacikova L
- Kox M
- Kraegpoeth A
- Krenn CG
- Krishna B
- Kristof J
- Kruger A
- Kruger A
- Krüger A
- Ku NS
- Ku NS
- Kubik M
- Kubota K
- Kuebler WM
- Kulaga EV
- Kulkarni AP
- Kumari BK
- Kumbamu A
- Kunze-Szikszay N
- Kurmukov IA
- Kurth T
- Kurtz P
- Kurtz P
- Kwon HM
- Kwon HM
- Kwon WY
- Kwon WY
- Kwon WY
- Kye YC
- Kyle UG
- Kyle UG
- Labaune MA
- Labra C
- Lacerda P
- Laerkner E
- Lafaurie M
- Lafuente E
- Lagonidis D
- Lagos R
- Lahmer T
- Lai CC
- Lai CH
- Lake K
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- Lapteva K
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- Latini R
- Latini R
- Latini R
- Latorre J
- Lattuada M
- Lattuada M
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- Laurent A
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- Le Brocque R
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- Lebiedz P
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- Lee EY
- Lee JH
- Lee S
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- Lee SJ
- Lee WY
- Lee YJ
- Lee YJ
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- Legrand M
- Legrand M
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- Leitao AL
- Leite RT
- Leonard H
- Leone M
- Leone M
- Lerma FA
- Lesmes SP
- Lesmes SP
- Lesmes SP
- Lesmes SP
- Lesmes SP
- Lesmes SP
- Letizia T
- Levrat Q
- Levy B
- León JL
- León JP
- León JP
- León JP
- Lheureux O
- Lheureux O
- Lheureux O
- Lheureux O
- Li R
- Li SH
- Liao X
- Lichtenstein D
- Lim TH
- Limuti R
- Lin KC
- Lin KC
- Lin KC
- Lin KC
- Lin KL
- Lin PH
- Lin SC
- Lin SC
- Lin SC
- Lin SC
- Lin WC
- Lin WC
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- Lischinsky A
- Lissonde F
- Lissonde F
- Litchfield K
- Liu CP
- Liu CP
- Liu CP
- Liu CP
- Liu D
- Llaurado-Serra M
- Llorente B
- Llorente MÁ
- Lobato MS
- Lobo-Civico A
- Loizou C
- Lombardo MD
- Londoño JG
- Longani N
- Longhi L
- Lopes JA
- Lopez GD
- Lopez R
- Lopez-Caler C
- Lopez-Gude MJ
- Lorini L
- Lortat-Jacob B
- Lortat-Jacob B
- Lotay R
- Loudet CI
- Louf-Durier A
- Louf-Durier A
- Louis B
- Lourido CM
- Lozano JA
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- Lucendo AP
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- Lucinio NM
- Luini M
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- Lukaszewicz AC
- Luna RR
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- Lusk J
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- Lázaro AS
- López AR
- López L
- López MA
- Macfarlane B
- MacKay A
- MacKay A
- Mackey G
- Mackey G
- MacPhee I
- Macrì M
- Madueño VP
- Maekawa K
- Maekawa K
- Maekawa K
- Maekawa K
- Maertens B
- Maggiorini M
- Maghsoudi B
- Magnanimi E
- Magnoni S
- Magret M
- Mainardi JL
- Maistry N
- Maitra S
- Makiko S
- Malagurski B
- Malek F
- Malo LR
- Maly M
- Malyshev A
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- Mancebo J
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- Mancino A
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- Marcos-Zambrano LJ
- Mariani M
- Mariman A
- Marin-Mateos H
- Marine-Vidal J
- Mariotte E
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- Marmanidou K
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- Martinez-Reyes L
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- Martínez F
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- Martínez-Carmona JF
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- Melo N
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- Mendonca AV
- Mendsaikhan N
- Menendez R
- Mengelle C
- Mercat A
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- Mergulhão PJ
- Merino-Vega D
- Messenger D
- Mezidi M
- Mezidi M
- Michel L
- Midwinter MJ
- Mignot T
- Miguelena PR
- Mihara Y
- Millar M
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- Mimoz O
- Min A
- Min HJ
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- Miranda F
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- Mistry M
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- Mitchell M
- Mitchell S
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- Mizugaki A
- Mizugaki A
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- Olaechea P
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- Philips BJ
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- Radu V
- Rai S
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- Rodríguez FG
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- Romero I
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- Spahn DR
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- Spijkstra JJ
- Spronk PE
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- Sprung CL
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- Stamm J
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- Stanić R
- Starczewska M
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- Stiphout C
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- Stocchetti N
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- Stretti F
- Struijs A
- Stubbs C
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- Stümpfle R
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- Su PL
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- Suchomel P
- Suh GJ
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- Suh JW
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- Sun WZ
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- Suzuki T
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- Sánchez B
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- Sánchez EC
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- Tabatabaei HR
- Tabei SH
- Taccone F
- Taccone FS
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- Taccone FS
- Taccone FS
- Taccone FS
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- Taggu A
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- Takaki S
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- Takeda M
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- Takei T
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- Tamura T
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- Tanaka S
- Tanaka S
- Tane N
- Tang KB
- Tang LK
- Tapia A
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- Tapponnier R
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- Temprano-Gómez I
- Tena SA
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- Terzi N
- Terzi N
- Terzi N
- Terzi N
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- Thabut G
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- Thompson E
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- Tirkkonen J
- Tirumala S
- Tjepkema-Cloostermans MC
- Tobar M
- Tofiño AL
- Toh CH
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- Tomas E
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- Tonetti T
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- Wildenberg L
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- WIND study group
- WIND study group
- WIND study group
- Winder-Rhodes S
- Witter T
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- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Alcohol use and burden for 195 countries and territories, 1990-2016 : a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abate Degu
- Abate Kalkidan Hassen
- Abay Solomon M
- Abbafati Cristiana
- Abdulkader Rizwan Suliankatchi
- Abebe Zegeye
- Aboyans Victor
- Abrar Mohammed Mehdi
- Acharya Pawan
- Adetokunboh Olatunji O
- Adhikari Tara Ballav
- Adsuar Jose C
- Afarideh Mohsen
- Agardh Emilie Elisabet
- Agarwal Gina
- Aghayan Sargis Aghasi
- Agrawal Sutapa
- Ahmed Muktar Beshir
- Akibu Mohammed
- Akinyemiju Tomi
- Akseer Nadia
- Al-Aly Ziyad
- Alahdab Fares
- Alam Khurshid
- Albujeer Ammar
- Alene Kefyalew Addis
- Ali Raghib
- Ali Syed Danish
- Alijanzadeh Mehran
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Allebeck Peter
- Alvis-Guzman Nelson
- Amare Azmeraw T
- Aminde Leopold N
- Ammar Walid
- Amoako Yaw Ampem
- Amul Gianna Gayle Herrera
- Andrei Catalina Liliana
- Angus Colin
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T
- Aremu Olatunde
- Arian Nicholas
- Artaman Al
- Aryal Krishna K
- Asfoor Deena H Al
- Assadi Reza
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide F
- Awasthi Ashish
- Ayele Henok Tadesse
- Ayer Rakesh
- Ayuk Tambe B
- Azzopardi Peter S
- Badali Hamid
- Badawi Alaa
- Banach Maciej
- Barker-Collo Suzanne Lyn
- Barrero Lope H
- Basaleem Huda
- Baye Estifanos
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Belachew Abate Bekele
- Belay Saba Abraham
- Bennett Derrick A
- Bensenor Isabela M
- Bernabe Eduardo
- Bernstein Robert S
- Beyene Addisu Shunu
- Beyranvand Tina
- Bhaumik Soumyadeeep
- Bhutta Zulfiqar A
- Biadgo Belete
- Bijani Ali
- Bililign Nigus
- Birlik Sait Mentes
- Birungi Charles
- Bizuneh Hailemichael
- Bjerregaard Peter
- Bjørge Tone
- Borges Guilherme
- Bosetti Cristina
- Boufous Soufiane
- Bragazzi Nicola Luigi
- Brenner Hermann
- Butt Zahid A
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Calabria Bianca
- Campos-Nonato Ismael R
- Campuzano Julio Cesar
- Carreras Giulia
- Carrero Juan J
- Carvalho Félix
- Castañeda-Orjuela Carlos A
- Castillo Rivas Jacqueline
- Catalá-López Ferrán
- Chang Jung-Chen
- Charlson Fiona J
- Chattopadhyay Aparajita
- Chaturvedi Pankaj
- Chowdhury Rajiv
- Christopher Devasahayam J
- Chung Sheng-Chia
- Ciobanu Liliana G
- Claro Rafael M
- Conti Sara
- Cousin Ewerton
- Criqui Michael H
- Dachew Berihun Assefa
- Dargan Paul I
- Daryani Ahmad
- Das Neves José
- Davletov Kairat
- De Castro Filipa
- De Courten Barbora
- De Neve Jan-Walter
- Degenhardt Louisa
- Demoz Gebre Teklemariam
- Des Jarlais Don C
- Dey Subhojit
- Dhaliwal Rupinder Singh
- Dharmaratne Samath Dhamminda
- Dhimal Meghnath
- Doku David Teye
- Doyle Kerrie E
- Dubey Manisha
- Dubljanin Eleonora
- Duncan Bruce B
- Ebrahimi Hedyeh
- Edessa Dumessa
- El Sayed Zaki Maysaa
- Ermakov Sergei Petrovich
- Erskine Holly E
- Esteghamati Alireza
- Faramarzi Mahbobeh
- Farioli Andrea
- Faro Andre
- Farvid Maryam S
- Farzadfar Farshad
- Feigin Valery L
- Felisbino-Mendes Mariana Santos
- Fernandes Eduarda
- Ferrari Alize J
- Ferri Cleusa P
- Fijabi Daniel Obadare
- Filip Irina
- Finger Jonas David
- Fischer Florian
- Flaxman Abraham D
- Forouzanfar Mohammad H
- Franklin Richard Charles
- Fullman Nancy
- Futran Neal D
- Gakidou Emmanuela
- Gallus Silvano
- Ganji Morsaleh
- Gankpe Fortune Gbetoho
- Gebregergs Gebremedhin Berhe
- Gebrehiwot Tsegaye Tewelde
- Geleijnse Johanna M
- Ghadimi Reza
- Ghandour Lilian A
- Ghimire Mamata
- Gill Paramjit Singh
- Ginawi Ibrahim Abdelmageed
- Giref Ababi Zergaw Z
- Gona Philimon N
- Gopalani Sameer Vali
- Gotay Carolyn C
- Goulart Alessandra C
- Greaves Felix
- Griswold Max G
- Grosso Giuseppe
- Guo Yuming
- Gupta Rahul
- Gupta Rajeev
- Gupta Vipin
- Gutiérrez Reyna Alma
- GVS Murthy
- Hafezi-Nejad Nima
- Hagos Tekleberhan Beyene
- Hailu Gessessew Bugssa
- Hamadeh Randah R
- Hankey Graeme J
- Harb Hilda L
- Harikrishnan Sivadasanpillai
- Haro Josep Maria
- Hassen Hamid Yimam
- Havmoeller Rasmus
- Hawley Caitlin
- Hay Simon I
- Heibati Behzad
- Henok Andualem
- Heredia-Pi Ileana
- Hernández-Llanes Norberto Francisco
- Herteliu Claudiu
- Hibstu Desalegn Ts Tsegaw
- Hoogar Praveen
- Horita Nobuyuki
- Hosgood H Dean
- Hosseini Mostafa
- Hostiuc Mihaela
- Hu Guoqing
- Huang Hsiang
- Husseini Abdullatif
- Idrisov Bulat
- Ileanu Bogdan Vasile
- Ilesanmi Olayinka Stephen
- Irvani Seyed Sina Naghibi
- Islam Sheikh Mohammed Shariful
- Jackson Maria D
- Jakovljevic Mihajlo
- Jalu Moti Tolera
- Jayatilleke Achala Upendra
- Jha Ravi Prakash
- Jonas Jost B
- Jozwiak Jacek Jerzy
- Kabir Zubair
- Kadel Rajendra
- Kahsay Amaha
- Kapil Umesh
- Kasaeian Amir
- Kassa Tesfaye D Dessale
- Katikireddi Srinivasa Vittal
- Kawakami Norito
- Kebede Seifu
- Kefale Adane Teshome
- Keiyoro Peter Njenga
- Kengne Andre Pascal
- Khader Yousef
- Khafaie Morteza Abdullatif
- Khalil Ibrahim A
- Khan Md Nuruzzaman
- Khang Young-Ho
- Khater Mona M
- Khubchandani Jagdish
- Kim Cho-Il
- Kim Daniel
- Kim Yun Jin
- Kimokoti Ruth W
- Kisa Adnan
- Kivimäki Mika
- Kochhar Sonali
- Kosen Soewarta
- Koul Parvaiz A
- Koyanagi Ai
- Krishan Kewal
- Kuate Defo Barthelemy
- Kucuk Bicer Burcu
- Kulkarni Veena S
- Kumar Pushpendra
- Lafranconi Alessandra
- Lakshmana Balaji Arjun
- Lalloo Ratilal
- Lallukka Tea
- Lam Hilton
- Lami Faris Hasan
- Lan Qing
- Lang Justin J
- Lansky Sonia
- Larsson Anders O
- Latifi Arman
- Leasher Janet L
- Lee Paul H
- Leigh James
- Leinsalu Mall
- Leung Janni
- Levi Miriam
- Li Yichong
- Lim Lee-Ling
- Lobato-Cordero Andrea
- Lopez Alan D
- Lotufo Paulo A
- Macarayan Erlyn Rachelle King
- Machado Isis Eloah
- Madotto Fabiana
- Magdy Abd El Razek Hassan
- Magdy Abd El Razek Muhammed
- Majdan Marek
- Majdzadeh Reza
- Majeed Azeem
- Malekzadeh Reza
- Malta Deborah Carvalho
- Mapoma Chabila Christopher
- Martinez-Raga Jose
- Maulik Pallab K
- Mazidi Mohsen
- Mckee Martin
- Mehta Varshil
- Meier Toni
- Mekonen Tesfa
- Meles Kidanu Gebremariam
- Melese Addisu
- Memiah Peter T N
- Mendoza Walter
- Mengistu Desalegn Tadese
- Mensah George A
- Meretoja Tuomo J
- Mezgebe Haftay Berhane
- Miazgowski Tomasz
- Miller Ted R
- Mini Gk
- Mirica Andreea
- Mirrakhimov Erkin M
- Moazen Babak
- Mohammad Karzan Abdulmuhsin
- Mohammadifard Noushin
- Mohammed Shafiu
- Mokdad Ali H
- Monasta Lorenzo
- Moraga Paula
- Morawska Lidia
- Mousavi Seyyed Meysam
- Mukhopadhyay Satinath
- Murray Christopher J L
- Musa Kamarul Imran
- Naghavi Mohsen
- Naheed Aliya
- Naik Gurudatta
- Najafi Farid
- Nangia Vinay
- Nansseu Jobert Richie
- Nayak Mudavath Siva Durga Prasad
- Nejjari Chakib
- Neupane Subas
- Neupane Sudan Prasad
- Ngunjiri Josephine W
- Nguyen Cuong Tat
- Nguyen Long Hoang
- Nguyen Trang Huyen
- Ningrum Dina Nur Anggraini
- Nirayo Yirga Legesse
- Noubiap Jean Jacques
- Ofori-Asenso Richard
- Ogbo Felix Akpojene
- Oh In-Hwan
- Oladimeji Olanrewaju
- Olagunju Andrew T
- Olivares Pedro R
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Oommen Anu Mary
- Oren Eyal
- Orpana Heather M
- Ortega-Altamirano Doris D V
- Ortiz Justin R
- Ota Erika
- Owolabi Mayowa Ojo
- Oyekale Abayomi Samuel
- P A Mahesh
- Pana Adrian
- Park Eun-Kee
- Parry Charles D H
- Parsian Hadi
- Patle Ajay
- Patton George C
- Paudel Deepak
- Petzold Max
- Phillips Michael R
- Phillips Michael R
- Pillay Julian David
- Pillay Julian David
- Postma Maarten J
- Postma Maarten J
- Pourmalek Farshad
- Pourmalek Farshad
- Prabhakaran Dorairaj
- Qorbani Mostafa
- Radfar Amir
- Rafay Anwar
- Rafiei Alireza
- Rahim Fakher
- Rahimi-Movaghar Afarin
- Rahman Mahfuzar
- Rahman Muhammad Aziz
- Rai Rajesh Kumar
- Rajsic Sasa
- Raju Sree Bhushan
- Ram Usha
- Rana Saleem M
- Ranabhat Chhabi Lal
- Rawaf David Laith
- Rawaf Salman
- Reiner Robert C
- Reis Cesar
- Renzaho Andre M N
- Rezai Mohammad Sadegh
- Roever Leonardo
- Ronfani Luca
- Room Robin
- Roshandel Gholamreza
- Rostami Ali
- Roth Gregory A
- Roy Ambuj
- Sabde Yogesh Damodar
- Saddik Basema
- Safiri Saeid
- Sahebkar Amirhossein
- Salama Joseph S
- Salama Joseph S
- Saleem Zikria
- Salomon Joshua A
- Salvi Sundeep Santosh
- Sanabria Juan
- Sanchez-Niño Maria Dolores
- Santomauro Damian Francesco
- Santos Itamar S
- Santric Milicevic Milena M M
- Sarker Abdur Razzaque
- Sarmiento-Suárez Rodrigo
- Sarrafzadegan Nizal
- Sartorius Benn
- Satpathy Maheswar
- Sawhney Monika
- Saxena Sonia
- Saylan Mete
- Schaub Michael P
- Schmidt Maria Inês
- Schneider Ione J C
- Schutte Aletta Elisabeth
- Schwendicke Falk
- Schöttker Ben
- Sepanlou Sadaf G
- Shaikh Masood Ali
- Sharif Mehdi
- She Jun
- Sheikh Aziz
- Shen Jiabin
- Shiferaw Mekonnen Sisay
- Shigematsu Mika
- Shiri Rahman
- Shishani Kawkab
- Shiue Ivy
- Shukla Sharvari Rahul
- Sigfusdottir Inga Dora
- Silva Diego Augusto Santos
- Silva Natacha Torres Da
- Silveira Dayane Gabriele Alves
- Sinha Dhirendra Narain
- Sitas Freddy
- Soares Filho Adauto Martins
- Soofi Moslem
- Sorensen Reed J D
- Soriano Joan B
- Sreeramareddy Chandrashekhar T
- Steckling Nadine
- Stein Dan J
- Sufiyan Mu'awiyyah Babale
- Sur Patrick J
- Sykes Bryan L
- Tabarés-Seisdedos Rafael
- Tabuchi Takahiro
- Tapp Austin Douglas
- Tavakkoli Mohammad
- Tehrani-Banihashemi Arash
- Tekle Merhawi Gebremedhin
- Thapa Subash
- Thomas Nihal
- Topor-Madry Roman
- Topouzis Fotis
- Tran Bach Xuan
- Troeger Christopher E
- Truelsen Thomas Clement
- Tsilimparis Nikolaos
- Tymeson Hayley D
- Tyrovolas Stefanos
- Ukwaja Kingsley Nnanna
- Ullah Irfan
- Uthman Olalekan A
- Valdez Pascual R
- Van Boven Job F M
- Vasankari Tommi Juhani
- Venkateswaran Vidhya
- Venketasubramanian Narayanaswamy
- Violante Francesco S
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vollset Stein Emil
- Vos Theo
- Wagnew Fasil Wagnew Shiferaw
- Waheed Yasir
- Wang Yuan-Pang
- Weiderpass Elisabete
- Weldegebreal Fitsum
- Weldegwergs Kidu Gidey
- Werdecker Andrea
- Westerman Ronny
- Whiteford Harvey A
- Widecka Justyna
- Wijeratne Tissa
- Wyper Grant M A
- Xu Gelin
- Yamada Tomohide
- Yano Yuichiro
- Ye Pengpeng
- Yimer Ebrahim M
- Yip Paul
- Yirsaw Biruck Desalegn
- Yisma Engida
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z
- Zachariah Geevar
- Zaidi Zoubida
- Zamani Mohammad
- Zhang Xueying
- Zimsen Stephanie R M
- Zodpey Sanjay
- Ärnlöv Johan
- Publication venue
- Publication date
- 01/01/2018
- Field of study
Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life-years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2.2% (95% uncertainty interval [UI] 1.5-3.0) of age-standardised female deaths and 6.8% (5.8-8.0) of age-standardised male deaths. Among the population aged 15-49 years, alcohol use was the leading risk factor globally in 2016, with 3.8% (95% UI 3.2-4-3) of female deaths and 12.2% (10.8-13-6) of male deaths attributable to alcohol use. For the population aged 15-49 years, female attributable DALYs were 2.3% (95% UI 2.0-2.6) and male attributable DALYs were 8.9% (7.8-9.9). The three leading causes of attributable deaths in this age group were tuberculosis (1.4% [95% UI 1. 0-1. 7] of total deaths), road injuries (1.2% [0.7-1.9]), and self-harm (1.1% [0.6-1.5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27.1% (95% UI 21.2-33.3) of total alcohol-attributable female deaths and 18.9% (15.3-22.6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0.0-0.8) standard drinks per week. Interpretation Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that the risk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.Peer reviewe
Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
- Author
- Abate D
- Abate KH
- Abay SM
- Abbafati C
- Abd El Razek HM
- Abd El Razek MM
- Abdulkader RS
- Abebe Z
- Aboyans V
- Abrar MM
- Acharya P
- Adetokunboh OO
- Adhikari TB
- Adsuar JC
- Afarideh M
- Agardh EE
- Agarwal G
- Aghayan SA
- Agrawal S
- Ahmed MB
- Akibu M
- Akinyemiju T
- Akseer N
- Al Asfoor DH
- Al-Aly Z
- Alahdab F
- Alam K
- Albujeer A
- Alene KA
- Ali R
- Ali SD
- Alijanzadeh M
- Aljunid SM
- Alkerwi A
- Allebeck P
- Alma Gutierrez R
- Alves Silveira DG
- Alvis-Guzman N
- Amare AT
- Aminde LN
- Ammar W
- Amoako YA
- Amul GGH
- Andrei CL
- Angus C
- Ansha MG
- Antonio CAT
- Aremu O
- Arian N
- Arnlov J
- Artaman A
- Aryal KK
- Assadi R
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Awasthi A
- Ayele HT
- Ayer R
- Ayuk TB
- Azzopardi PS
- Badali H
- Badawi A
- Balaji AL
- Banach M
- Barker-Collo SL
- Barrero LH
- Basaleem H
- Baye E
- Bazargan-Hejazi S
- Bedi N
- Bejot Y
- Belachew AB
- Belay SA
- Bennett DA
- Bensenor IM
- Bernabe E
- Bernstein RS
- Beyene AS
- Beyranvand T
- Bhaumik S
- Bhutta ZA
- Biadgo B
- Bicer BK
- Bijani A
- Bililign N
- Birlik SM
- Birungi C
- Bizuneh H
- Bjerregaard P
- Bjorge T
- Borges G
- Bosetti C
- Boufous S
- Bragazzi NL
- Brenner H
- Butt ZA
- Cahuana-Hurtado L
- Calabria B
- Campos-Nonato IR
- Campuzano Rincon JC
- Carreras G
- Carrero JJ
- Carvalho F
- Castaneda-Orjuela CA
- Castillo Rivas J
- Catala-Lopez F
- Chang J-C
- Charlson FJ
- Chattopadhyay A
- Chaturvedi P
- Chowdhury R
- Christopher DJ
- Chung S-C
- Ciobanu LG
- Claro RM
- Conti S
- Cousin E
- Criqui MH
- Cuong TN
- Da Silva NT
- Dachew BA
- Dargan P
- Daryani A
- Das Neves J
- Davletov K
- De Castro F
- De Courten B
- De Neve J-W
- Defo BK
- Degenhardt L
- Demoz GT
- Des Jarlais DC
- Dey S
- Dhaliwal RS
- Dharmaratne SD
- Dhimal M
- Doku DT
- Dolores Sanchez-Nino M
- Doyle KE
- Dubey M
- Dubljanin E
- Duncan BB
- Ebrahimi H
- Edessa D
- Ermakov SP
- Erskine HE
- Esteghamati A
- Faramarzi M
- Farioli A
- Faro A
- Farvid MS
- Farzadfar F
- Feigin VL
- Felisbino-Mendes MS
- Fernandes E
- Ferrari AJ
- Ferri CP
- Fijabi DO
- Filip I
- Finger JD
- Fischer F
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- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 22/09/2018
- Field of study
BACKGROUND:
Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life-years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older.
METHODS:
Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health.
FINDINGS:
Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age-standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks per week.
INTERPRETATION:
Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that the risk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.
FUNDING:
Bill & Melinda Gates Foundation
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- Raju S. B.
- Ram U.
- Rana S. M.
- Ranabhat C. L.
- Rawaf D. L.
- Rawaf S.
- Reiner R. C.
- Reis C.
- Renzaho Andre M. N. (R17978)
- Rivas J. C.
- Salama J. S.
- Tapp A. D.
- Tymeson H. D.
- Venkateswaran V.
- Zaki M. E. S.
- Zimsen S. R.
- Ärnlöv J.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we generated improved estimates of alcohol use and alcohol-attributable deaths and disability-adjusted life-years (DALYs) for 195 locations from 1990 to 2016, for both sexes and for 5-year age groups between the ages of 15 years and 95 years and older. Methods: Using 694 data sources of individual and population-level alcohol consumption, along with 592 prospective and retrospective studies on the risk of alcohol use, we produced estimates of the prevalence of current drinking, abstention, the distribution of alcohol consumption among current drinkers in standard drinks daily (defined as 10 g of pure ethyl alcohol), and alcohol-attributable deaths and DALYs. We made several methodological improvements compared with previous estimates: first, we adjusted alcohol sales estimates to take into account tourist and unrecorded consumption; second, we did a new meta-analysis of relative risks for 23 health outcomes associated with alcohol use; and third, we developed a new method to quantify the level of alcohol consumption that minimises the overall risk to individual health. Findings: Globally, alcohol use was the seventh leading risk factor for both deaths and DALYs in 2016, accounting for 2·2% (95% uncertainty interval [UI] 1·5–3·0) of age-standardised female deaths and 6·8% (5·8–8·0) of age-standardised male deaths. Among the population aged 15–49 years, alcohol use was the leading risk factor globally in 2016, with 3·8% (95% UI 3·2–4·3) of female deaths and 12·2% (10·8–13·6) of male deaths attributable to alcohol use. For the population aged 15–49 years, female attributable DALYs were 2·3% (95% UI 2·0–2·6) and male attributable DALYs were 8·9% (7·8–9·9). The three leading causes of attributable deaths in this age group were tuberculosis (1·4% [95% UI 1·0–1·7] of total deaths), road injuries (1·2% [0·7–1·9]), and self-harm (1·1% [0·6–1·5]). For populations aged 50 years and older, cancers accounted for a large proportion of total alcohol-attributable deaths in 2016, constituting 27·1% (95% UI 21·2–33·3) of total alcohol-attributable female deaths and 18·9% (15·3–22·6) of male deaths. The level of alcohol consumption that minimised harm across health outcomes was zero (95% UI 0·0–0·8) standard drinks per week. Interpretation: Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that the risk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption. Funding: Bill & Melinda Gates Foundation
Recommended from our members
ESICM LIVES 2016: part three: Milan, Italy. 1–5 October 2016
- Author
- Abbott T. E. F.
- Abdallah R. I.
- Abdel-Aal I. R.
- Abdelmonem S. A.
- Abdo W. F.
- Abellan A. Naharro
- Abellán A. Naharro
- Abellán A. Navarro
- Abrams S. T.
- Ackerley C.
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 18/11/2016
- Field of study
A framework for assessing the impact of chemical exposures on neurodevelopment in ECHO: Opportunities and challenges
- Author
- Abid
- Adgent
- Andersen
- Anderson
- Anderson
- AnneMarie Stroustrup
- Arbuckle
- Arbuckle
- Arora
- Barr
- Barr
- Bearer
- Bellinger
- Bellinger
- Bellinger
- Bellinger
- Bellinger
- Bellinger
- Bellinger
- Bennett
- Blount
- Blount
- Bollmann
- Bornehag
- Bouchard
- Bouchard
- Boucher
- Bowler
- Bradman
- Bradway
- Braun
- Braun
- Braun
- Braun
- Braun
- Braun
- Braun
- Braun
- Braun
- Brenda Eskenazi
- Buckley
- Calafat
- Calafat
- Calafat
- Carwile
- Casas
- Casas
- Caspersen
- Caspersen
- Caspersen
- Chao
- Chapin
- Chatterjee
- Chen
- Chen
- Cheslack-Postava
- Children’s Health Exposure Analysis Resource [CHEAR]
- Chrustek
- Chung
- Claus Henn
- Coetzee
- Cordier
- Counter
- Cowell
- Dallaire
- Davidson
- de Graaf-Peters
- Deborah H. Bennett
- Deborah J. Watkins
- Desrochers-Couture
- Dewan
- Ding
- Doherty
- Donauer
- DuBois
- Dzwilewski
- Edwards
- Ehrlich
- Engel
- Engel
- Engel
- Eskenazi
- Eskenazi
- Eskenazi
- Eskenazi
- Eskenazi
- Evans
- Factor-Litvak
- Fei
- Fei
- Fenster
- Ferguson
- Fernandez-Cornejo
- Finkelstein
- Forns
- Forns
- Fortier
- Froehlich
- Furlong
- Garcia-Repetto
- Gascon
- Gascon
- Gascon
- Gaspar
- Geyer
- Goldman
- Gomez-Rubio
- Goodman
- Gore
- Grandjean
- Grandjean
- Grandjean
- Gray
- Guidry
- Gump
- Gunier
- Gunier
- Gunier
- Guodong
- Gupta
- Hall
- Hamadani
- Hamra
- Harley
- Harris
- Heather E. Volk
- Herbstman
- Hertz-Picciotto
- Hines
- Hoffman
- Hoffman
- Hoffman
- Hong
- Horton
- Huang
- Huang
- Huttenlocher
- Hyland
- Høyer
- Høyer
- Ipapo
- Irva Hertz-Picciotto
- Jacobson
- Jaishankar
- Jayaraj
- Jean A. Frazier
- Jedrychowski
- Jedrychowski
- Jenna N. Sprowles
- Jessie P. Buckley
- Johnnye Lewis
- Jose Cordero
- Joseph M. Braun
- Jurewicz
- Jurewicz
- Jusko
- Kalloo
- Kershaw
- Kessler
- Keyes
- Khan
- Khan
- Kim
- Kim
- Kim
- Kingsley
- Kjellstrom
- Kobrosly
- Koch
- Koch
- Korrick
- Kristen Lyall
- Kyriklaki
- Laine
- Lam
- Lanphear
- Latini
- Latini
- Lee
- Lee
- Leng
- Lesko
- Lien
- Lien
- Liew
- Liew
- Lin
- Liu
- Liu
- Lyall
- Lyall
- Lyall
- Maffini
- Marek
- Marks
- Menezes-Filho
- Menezes-Filho
- Millenson
- Miodovnik
- Mogensen
- Montes-Grajales
- Mora
- Mora
- Mora
- Morales
- Mori
- Mortamais
- Myers
- Nakajima
- Nakiwala
- Needham
- Needham
- Newman
- Newschaffer
- Ode
- Oken
- Olesen
- Olsen
- Orenstein
- Osteen
- Oulhote
- Oulhote
- Padula
- Pan
- Park
- Pasquet
- Perera
- Perera
- Perera
- Perera
- Perez-Lobato
- Perrier
- Pesch
- Peterson
- Polańska
- Puertas
- Quaak
- Quirós-Alcalá
- Radke
- Rauh
- Rauh
- Rauh
- Ribas-Fito
- Ribas-Fitó
- Rice
- Roberts
- Robinson
- Rodier
- Rodier
- Roen
- Rohlman
- Rosado
- Rosas
- Rowe
- Roy
- Sagiv
- Sagiv
- Sagiv
- Sagiv
- Sagiv
- Sagiv
- Sagiv
- Sara S. Nozadi
- Schantz
- Selevan
- Sharon Sagiv
- Shelton
- Sioen
- Sjödin
- Soderlund
- Stacy
- Stacy
- Stein
- Stein
- Steinmaus
- Stewart
- Stewart
- Stroustrup
- Strøm
- Susan L. Schantz
- Székács
- Sánchez
- Taylor
- Taylor
- Tewar
- Thayer
- Tolins
- Torres-Sánchez
- Traglia
- Trunnelle
- Tsuji
- Téllez-Rojo
- Uylings
- van Wendel de Joode
- van Wendel de Joode
- Vandenberg
- Ventrice
- Verner
- Verner
- Viel
- Viel
- von Ehrenstein
- Vrijheid
- Vuong
- Vuong
- Vuong
- Vuong
- Wagner-Schuman
- Wang
- Wani
- Wasserman
- Watkins
- Watson
- Weldon
- Whyatt
- Whyatt
- Wigle
- Williams
- Woodruff
- Wright
- Yamazaki
- Yolton
- Young
- Zartarian
- Zhang
- Zhang
- Zhang
- Zhang
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study