Análisis neuropsicológico de la epilepsia rolándica benigna y su comparación con el trastorno de hiperactividad en la edad escolar

El objetivo general de la tesis se enmarca dentro del ámbito de la neuropsicología clínica infantil, abordando dos patologías que presentan alteraciones cognitivas y conductuales sustentadas en disfunción cerebral: epilepsia rolándica benigna y trastorno por déficit de atención con hiperactividad (tdah). La evaluación neuropsicológica se llevó a cabo con la utilización de la batería luria-dni en muestras clínicas, ofreciendo amplios perfiles de competencias, que permiten establecer las habilidades neurocognitivas deficitarias características de estos dos síndromes, y el diagnóstico diferencial entre condiciones que cursan con sintomatología similar. El estudio de niños con epilepsia benigna rolándica, a través de una selección homogénea, muestra dificultades específicas en habla expresiva cuando la lateralización del foco epiléptico se halla en el hemisferio izquierdo (zona inferior rolándica). También se consiguieron resultados satisfactorios con el grupo de niños hiperactivos, al aparecer un perfil característico con déficit en la "regulación verbal del acto motor", con referencia a disfunción de los lóbulos frontales, según postula el modelo neuropsicológico de luria para la organización del cerebro en desarrollo; lo que sin duda ayuda a apoyar y hacer mas fiable el diagnostico conductual de este síndrome. Tales perfiles neuropsicológicos proporcionan una sólida base teórica que permite orientar la intervención desde una mejor comprensión de ambos trastornos

Análisis estático no lineal para la evaluación del desempeño sísmico de la I.E.I. N° 652-02 Santa Rosa de Lima en el sector 2 de la IV etapa de Pachacamac, Distrito Villa el Salvador, Lima Metropolitana

La problemática de esta investigación surge debido las múltiples quejas de parte de los usuarios de un grupo de siete instituciones educativas, construidas por la Municipalidad Distrital de Villa el Salvador en el año 2016, esto debido a la aparición de fisuras en gran parte de los elementos no estructurales, durante el primer año posterior a su ejecución. El objetivo principal de esta tesis es evaluar el desempeño sísmico de una de estas instituciones educativas, la I.E.I. N°. 652-02 “Santa Rosa De Lima”, mediante un análisis estático no-lineal, basado en los procedimientos y criterios establecidos por la norma ASCE 41-13, a fin de verificar si la estructura de la institución cumple con el desempeño estructural que corresponde, para de esta manera sosegar la intranquilidad de los ocupantes. La metodología utilizada consiste en la recolección de datos mediante ensayos e información de los planos de construcción, así como la inspección en campo y la posterior evaluación estructural a una muestra representativa: el pabellón de aulas N° 01 de la I.E.I. Santa Rosa de Lima. Para esto, se realizó el modelo matemático del Bloque de Aulas N° 01, considerando las características no-lineales de las secciones y materiales, sometiendo el modelo al análisis estático no lineal (Pushover). De los resultados del análisis, se observó que la estructura del Bloque de Aulas N° 01, no cumplió con los objetivos de desempeño establecidos por el código ASCE 41-13, para una edificación esencial. Debido a esto, se planteó una propuesta de adecuación y reforzamiento estructural, misma que consistió en aislar completamente los tabiques de albañilería existentes e incorporar placas de concreto armado en ambas direcciones. Los resultados de la evaluación de la edificación reforzada demostraron que, para los niveles de amenaza sísmica establecidos por el código ASCE 41-13, los niveles de desempeño obtenidos, son los adecuados para este tipo de edificacionesTesi

Especialidad sanitaria de psicología clínica de la infancia y la adolescencia: Una propuesta razonada

Clinical child and adolescent psychology is a healthcarespecialty of psychology that is recognized with its own identity in many countries. In the Spanish National Health System, its institutionalization runs parallel to that of Clinical Psychology, mainly after the psychiatric reform law, which has resulted in its gradual consolidation in the different health structures and ways of doing of clinical psychologists.The objective of this article is to make a reasoned reflection on some of the most relevant issues of the Clinical Psychology of Children and Adolescents that allows the necessary debate for the training of the specialists in this field.For this, a review is carried out on its history, competencies, areas of action and future development that enables its consolidation through the Spanish internship specialist training model for clinical psychology.Health-care specialty in clinical child and adolescent psychology: A reasoned proposal Abstract: Clinical child and adolescent psychology is a health care specialty in psychology that is recognized with its own identity in many countries. In the Spanish National Health System, its institutionalization runs parallel to the one related to clinical psychology, mainly after the psychiatric reform law, which has led to its gradual consolidation in the different health structures and ways of doing of clinical psychologists. The objective of this article was to make a reasoned reflection on some of the most relevant issues concerning clinical child and adolescent psychology that allows the debate necessary for the training of specialists in this field. After a brief review of its history, competencies and areas of action that enables its consolidation, as well as the future development of this specialty through the Spanish internship specialist training model for clinical psychology are described. Keywords: Clinical child and adolescent psychology, internship training in clinical psychology, specialized training, psychological treatments. Resumen: La psicología clínica de la infancia y adolescencia (PCIA) es una especialidad sanitaria de la psicología que está reconocida con identidad propia en muchos países. En el Sistema Nacional de Salud (SNS) de España, su institucionalización corre paralela a la de la psicología clínica, principalmente tras la reforma psiquiátrica, lo que ha dado lugar a su paulatino afianzamiento en las diferentes estructuras sanitarias y formas de hacer de los psicólogos clínicos. El objetivo de este artículo fue realizar una reflexión razonada sobre algunos de los aspectos más importantes de la PCIA, que permita el debate necesario para la formación del especialista en este ámbito. Después de una breve reseña sobre su historia, se describen las competencias y áreas de actuación que posibilitan su consolidación, así como el futuro desarrollo de esta especialidad, a través del modelo español de residencia para la formación sanitaria especializada en psicología clínica. Palabras clave: Psicología clínica de la infancia y adolescencia, PIR, formación especializada, tratamientos psicológicos

Reversal of SARS-CoV2-Induced Hypoxia by Nebulized Sodium Ibuprofenate in a Compassionate Use Program

Introduction: Sodium ibuprofenate in hypertonic saline (NaIHS) administered directly to the lungs by nebulization and inhalation has antibacterial and anti-inflammatory effects, with the potential to deliver these benefits to hypoxic patients. We describe a compassionate use program that offered this therapy to hospitalized COVID-19 patients. Methods: NaIHS (50 mg ibuprofen, tid) was provided in addition to standard of care (SOC) to hospitalized COVID-19 patients until oxygen saturation levels of > 94% were achieved on ambient air. Patients wore a containment hood to diminish aerosolization. Outcome data from participating patients treated at multiple hospitals in Argentina between April 4 and October 31, 2020, are summarized. Results were compared with a retrospective contemporaneous control (CC) group of hospitalized COVID-19 patients with SOC alone during the same time frame from a subset of participating hospitals from Córdoba and Buenos Aires. Results: The evolution of 383 patients treated with SOC + NaIHS [56 on mechanical ventilation (MV) at baseline] and 195 CC (21 on MV at baseline) are summarized. At baseline, NaIHS-treated patients had basal oxygen saturation of 90.7 ± 0.2% (74.3% were on supplemental oxygen at baseline) and a basal respiratory rate of 22.7 ± 0.3 breath/min. In the CC group, basal oxygen saturation was 92.6 ± 0.4% (52.1% were on oxygen supplementation at baseline) and respiratory rate was 19.3 ± 0.3 breath/min. Despite greater pulmonary compromise at baseline in the NaIHS-treated group, the length of treatment (LOT) was 9.1 ± 0.2 gs with an average length of stay (ALOS) of 11.5 ± 0.3 days, in comparison with an ALOS of 13.3 ± 0.9 days in the CC group. In patients on MV who received NaIHS, the ALOS was lower than in the CC group. In both NaIHS-treated groups, a rapid reversal of deterioration in oxygenation and NEWS2 scores was observed acutely after initiation of NaIHS therapy. No serious adverse events were considered related to ibuprofen therapy. Mortality was lower in both NaIHS groups compared with CC groups. Conclusions: Treatment of COVID-19 pneumonitis with inhalational nebulized NaIHS was associated with rapid improvement in hypoxia and vital signs, with no serious adverse events attributed to therapy. Nebulized NaIHS s worthy of further study in randomized, placebo-controlled trials (ClinicalTrials.gov: NCT04382768).Fil: Salva, Oscar. Clínica Independencia; ArgentinaFil: Doreski, Pablo A.. Fundación Respirar; ArgentinaFil: Giler, Celia S.. Clínica Independencia; ArgentinaFil: Quinodoz, Dario C.. Sanatorio de la Cañada; ArgentinaFil: Guzmán, Lucia G.. Sanatorio de la Cañada; ArgentinaFil: Muñoz, Sonia Edith. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Carrillo, Mariana Norma del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Porta, Daniela Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Ambasch, Germán. Sanatorio Privado Mayo; ArgentinaFil: Coscia, Esteban. Sanatorio Privado Mayo; ArgentinaFil: Tambini Diaz, Jorge L.. Sanatorio Privado Mayo; ArgentinaFil: Bueno, Germán D.. Sanatorio Privado Mayo; ArgentinaFil: Fandi, Jorge O.. Clínica Independencia; ArgentinaFil: Maldonado, Miriam A.. Sanatorio San Roque; ArgentinaFil: Peña Chiappero, Leandro E.. Sanatori San Roque; ArgentinaFil: Fournier, Fernando. Clínica Francesa; ArgentinaFil: Pérez, Hernán A.. Sanatorio Alive; Argentina. University of Maryland; Estados UnidosFil: Quiroga, Mauro A.. Instituto Modelo de Cardiología; ArgentinaFil: Sala Mercado, Javier Agustin. Instituto Modelo de Cardiología; ArgentinaFil: Martínez Picco, Carlos. Clínica del Sol; ArgentinaFil: Beltrán, Marcelo Alejandro. Hospital Dr. Alberto Duhau; ArgentinaFil: Castillo Argañarás, Luis Fernando. Hospital Dr. Alberto Duhau; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Ríos, Nicolás Martínez. Quimica Luar Srl; ArgentinaFil: Kalayan, Galia I.. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; ArgentinaFil: Beltramo, Dante Miguel. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Garcia, Nestor Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Provincia de Córdoba. Ministerio de Ciencia y Técnica. Centro de Excelencia en Productos y Procesos de Córdoba; Argentin

Hadron Energy Reconstruction for the ATLAS Calorimetry in the Framework of the Non-parametrical Method

This paper discusses hadron energy reconstruction for the ATLAS barrel prototype combined calorimeter (consisting of a lead-liquid argon electromagnetic part and an iron-scintillator hadronic part) in the framework of the non-parametrical method. The non-parametrical method utilizes only the known $e/h$ ratios and the electron calibration constants and does not require the determination of any parameters by a minimization technique. Thus, this technique lends itself to an easy use in a first level trigger. The reconstructed mean values of the hadron energies are within $\pm 1$ of the true values and the fractional energy resolution is $[(58\pm3)/\sqrt{E}+(2.5\pm0.3)$. The value of the $e/h$ ratio obtained for the electromagnetic compartment of the combined calorimeter is $1.74\pm0.04$ and agrees with the prediction that $e/h > 1.7$ for this electromagnetic calorimeter. Results of a study of the longitudinal hadronic shower development are also presented. The data have been taken in the H8 beam line of the CERN SPS using pions of energies from 10 to 300 GeV.Comment: 33 pages, 13 figures, Will be published in NIM

Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector

This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}$and correspond to an integrated luminosity of$4.6\;{\rm f}{{{\rm b}}^{-1}}$. The measurement is performed by reconstructing the boosted W or Z bosons in single jets. The reconstructed jet mass is used to identify the W and Z bosons, and a jet substructure method based on energy cluster information in the jet centre-of-mass frame is used to suppress the large multi-jet background. The cross-section for events with a hadronically decaying W or Z boson, with transverse momentum${{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}$and pseudorapidity$|\eta |\lt 1.9$, is measured to be${{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques

Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector

Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02  TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1  μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos⁡2Δϕ modulation for all ΣETPb ranges and particle pT

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

This paper presents measurements of the $W^+ \rightarrow \mu^+\nu$ and $W^- \rightarrow \mu^-\nu$ cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13

Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector

Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente