62 research outputs found

    Violence Against Women Through the Lens of Objectification Theory

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    The purpose of this research was to examine the effects of violence on body image variables for college women. Undergraduate women participated in an online study assessing sexual violence (SV), intimate partner violence (IPV), self-objectification, body surveillance, and body shame experiences. Findings suggest that both SV and IPV contribute to women’s body shame. In addition, the associations between IPV and body shame appear to be explained through self-objectification processes, but not the associations between SV and body shame. Thus, important differences between IPV and SV regarding self-objectification processes emerged. Theoretical and practical implications, as well as directions for future research, are discussed

    Relations Between Intimate Partner Violence and Forgiveness Among College Women

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    The purpose of the current investigation was to examine forgiveness and intimate partner violence (IPV) among college women. Undergraduate women (N = 502) participated in an online study in which overall experiences of IPV, as well as experiences of psychological and physical IPV, were investigated with respect to transgression-specific and dispositional forgiveness. Simultaneous multivariate regressions revealed that (a) the experience of IPV was associated with higher levels of avoidance and revenge, and lower levels of benevolence, forgiveness of self, forgiveness of others, and forgiveness of uncontrollable situations; (b) types of IPV demonstrated differing impacts on forgiveness; and (c) the mere experience of IPV is more salient than its frequency

    Relations Between Intimate Partner Violence and Forgiveness Among College Women

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    The purpose of the current investigation was to examine forgiveness and intimate partner violence (IPV) among college women. Undergraduate women (N = 502) participated in an online study in which overall experiences of IPV, as well as experiences of psychological and physical IPV, were investigated with respect to transgression-specific and dispositional forgiveness. Simultaneous multivariate regressions revealed that (a) the experience of IPV was associated with higher levels of avoidance and revenge, and lower levels of benevolence, forgiveness of self, forgiveness of others, and forgiveness of uncontrollable situations; (b) types of IPV demonstrated differing impacts on forgiveness; and (c) the mere experience of IPV is more salient than its frequency

    Investigating the Justice System Response to Domestic Violence in Missouri

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    One in four women will experience domestic violence in their lifetimes. Each year, 5.3 million domestic violence assaults occur in the United States alone and domestic violence is the leading cause of injury to women. Yet, despite the prevalence of domestic violence, little empirical research on the justice system\u27s response to it exists. This paper seeks to describe a state funded project that was created to assess and compare responses to domestic violence throughout the state of Missouri. The project lasted for three years and was conducted by an interdisciplinary team of University of Missouri-Columbia (MU) professors and students

    An Integrated Conceptual Framework Linking Attachment Insecurity to Increased Risk for Both Enacting and Experiencing Objectification

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    Sexual objectification (i.e., reducing a person to their appearance, body, or sex appeal and functions) is a significant risk factor for negative health outcomes. In the present investigation, we examined multiple manifestations of objectification (i.e., objectification of others, objectification of self, and objectification by others) in an interpersonal context. We merged objectification theory with attachment theory, one of the most prominent theories of close relationships, and propose that sexual objectification can shed light on attachment processes (and vice versa). To bolster this conceptual overlap, we tested this novel, integrated framework across two independent samples of women and men including (a) a sample of 813 undergraduate students—both partnered and single—who completed self-report questionnaires of attachment security and multiple forms of objectification and (b) a sample of 159 committed couples navigating pregnancy who were observed during naturalistic interactions to assess attachment security and completed self-report questionnaires of attachment security and objectification (including partner objectification). Results from both studies demonstrate the utility of our proposed conceptual framework linking attachment insecurity to increased risk for both enacting and experiencing objectification. The most compelling evidence emerged for (a) a link between attachment anxiety and self-objectification with moderate effect sizes across both samples, and (b) an association between a less secure base within the couple relationship during pregnancy and feeling more objectified by one’s partner as well as less humanized (i.e., feeling that your partner values you more for your physical attributes and less for your non-physical attributes)

    Strategies to Recruit and Retain College Smokers in Cessation Trials

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    Techniques to recruit and retain college fraternity and sorority members who reported past 30-day smoking into a cessation trial are described. Recruitment efforts included relationship-building, raffles, and screening survey administration during existing meetings. Surveys were administered to 76% (n = 3,276) of members in 30 chapters, 79% of eligible members agreed to participate, and 76% of those completed assessments and were enrolled in the trial (n = 452). The retention rate was 73%. Retention efforts included cash incentives, flexible scheduling, multiple reminders, chapter incentives, and use of chapter members as study personnel. Retention was not related to demographic, behavioral, or group characteristics. The strategies of partnership, convenience, and flexibility appear effective and may prove useful to investigators recruiting similar samples

    Adolescent Relationship Violence: Help-Seeking and Help-Giving Behaviors among Peers

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    Young people tend to disclose relationship violence experiences to their peers, if they disclose at all, yet little is known about the nature and frequency of adolescent help-seeking and help-giving behaviors. Conducted within a sample of 1,312 young people from four New York City high schools, this is the first paper to ask adolescent help-givers about the various forms of help they provide and among the first to examine how ethnicity and nativity impact help-seeking behaviors. Relationship violence victims who had ever disclosed (61 %) were more likely to choose their friends for informal support. Ethnicity was predictive of adolescent disclosure outlets, whereas gender and nativity were not. Latinos were significantly less likely than non-Latinos to ever disclose to only friends, as compared to disclosing to at least one adult. The likelihood of a young person giving help to their friend in a violent relationship is associated with gender, ethnicity, and nativity, with males being significantly less likely than females to give all forms of help to their friends (talking to their friends about the violence, suggesting options, and taking action). Foreign-born adolescents are less likely to talk or suggest options to friends in violent relationships. This study also found that Latinos were significantly more likely than non-Latinos to report taking action with or on behalf of a friend in a violent relationship. This research shows that adolescents often rely on each other to address relationship violence, underlining the importance of adolescents’ receipt of training and education on how to support their friends, including when to seek help from more formal services. To further understand the valuable role played by adolescent peers of victims, future research should explore both which forms of help are perceived by the victim to be most helpful and which are associated with more positive outcomes

    Microsomal Triglyceride Transfer Protein Transfers and Determines Plasma Concentrations of Ceramide and Sphingomyelin but Not Glycosylceramide

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    Sphingolipids, a large family of bioactive lipids, are implicated in stress responses, differentiation, proliferation, apoptosis, and other physiological processes. Aberrant plasma levels of sphingolipids contribute to metabolic disease, atherosclerosis, and insulin resistance. They are fairly evenly distributed in high density and apoB-containing lipoproteins (B-lps). Mechanisms involved in the transport of sphingolipids to the plasma are unknown. Here, we investigated the role of microsomal triglyceride transfer protein (MTP), required for B-lp assembly and secretion, in sphingolipid transport to the plasma. Abetalipoproteinemia patients with deleterious mutations in MTP and absence of B-lps had significantly lower plasma ceramide and sphingomyelin but normal hexosylceramide, lactosylceramide, and different sphingosines compared with unaffected controls. Furthermore, similar differential effects on plasma sphingolipids were seen in liver- and intestine-specific MTP knock-out (L,I-Mttp(-/-)) mice, suggesting that MTP specifically plays a role in the regulation of plasma ceramide and sphingomyelin. We hypothesized that MTP deficiency may affect either their synthesis or secretion. MTP deficiency had no effect on ceramide and sphingomyelin synthesis but reduced secretion from primary hepatocytes and hepatoma cells. Therefore, MTP is involved in ceramide and sphingomyelin secretion but not in their synthesis. We also found that MTP transferred these lipids between vesicles in vitro. Therefore, we propose that MTP might regulate plasma ceramide and sphingomyelin levels by transferring these lipids to B-lps in the liver and intestine and facilitating their secretion

    Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5

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    ATAD5, the human ortholog of yeast Elg1, plays a role in PCNA deubiquitination. Since PCNA modification is important to regulate DNA damage bypass, ATAD5 may be important for suppression of genomic instability in mammals in vivo. To test this hypothesis, we generated heterozygous (Atad5+/m) mice that were haploinsuffficient for Atad5. Atad5+/m mice displayed high levels of genomic instability in vivo, and Atad5+/m mouse embryonic fibroblasts (MEFs) exhibited molecular defects in PCNA deubiquitination in response to DNA damage, as well as DNA damage hypersensitivity and high levels of genomic instability, apoptosis, and aneuploidy. Importantly, 90% of haploinsufficient Atad5+/m mice developed tumors, including sarcomas, carcinomas, and adenocarcinomas, between 11 and 20 months of age. High levels of genomic alterations were evident in tumors that arose in the Atad5+/m mice. Consistent with a role for Atad5 in suppressing tumorigenesis, we also identified somatic mutations of ATAD5 in 4.6% of sporadic human endometrial tumors, including two nonsense mutations that resulted in loss of proper ATAD5 function. Taken together, our findings indicate that loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis

    Large expert-curated database for benchmarking document similarity detection in biomedical literature search

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    Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
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