1,994 research outputs found

    Monitoring SMEs’ performance in Europe: Methodological assessment of the SME Scoreboard 2017

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    The European Commission’s Directorate-General for Internal Market, Industry, Entrepreneurship and SMEs (DG GROW), with the scientific support by the European Commission Joint Research Centre (JRC), assesses the Performance of Small and Medium Enterprises in Europe, depending on the performance in the ten principles of: (1) Entrepreneurship, (2) ‘Second chance’, (3) ‘Think small first’, (4) ‘Responsive administration’, (5) State aid & public procurement, (6) Access to finance, (7) Single market, (8) Skills and innovation, (9) Environment, and (10) Internationalisation. This JRC technical report describes the underlying rationale behind the quantitative measurement of these principles and discusses the methodological approach which has been followed to calculate how countries perform in the outlined principles, from the choice of the indicators, to the data quality controls (including missing data and outliers), normalization and weightings, to the statistical coherence and robustness checks of the 2017 edition.JRC.I.1-Modelling, Indicators and Impact Evaluatio

    Access to finance and labor market performance in the EU 28

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    This paper examines the relationship between access to finance and labor market performance in the EU28 for the period 2003-2017. For this purpose, we first construct a composite indicator to measure access to finance by equal-weighting information about days needed to be paid, rejected loans, the willingness of banks to provide a loan, interest rate for small loans, venture capital, private equity, business angels, and public funding. Secondly, using a Two-Stage Least Squares (2SLS), we estimate the relationship between the employment and unemployment growth rates on our access to finance indicator while controlling for main macro-economic variables. Our results suggest that improved access to finance is likely to stimulate labor market performance - increased access to finance generates increased employment growth rates, and decreased unemployment growth rates respectively. Findings contribute to empirical literature and have important policy implications. Improving business environment conditions for SMEs through access to finance could improve labor market outcomes.JRC.I.1-Monitoring, Indicators & Impact Evaluatio

    Life Dissatisfaction and Anxiety in COVID-19 pandemic

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    The rising numbers of COVID-19 cases and deaths, prolonged lockdowns, substantial restrictions on public life and an economic downturn negatively affect personal well-being. In this paper, we explore COVID-19-related determinants of life dissatisfaction and feelings of anxiety using data collected from March 23 to April 30 2020 in 25 advanced and developing countries from four continents. We find that persons with better general health, with a paid job, living with a partner, daily exercising and those avoiding loneliness report less dissatisfaction and less anxiety. The presence of children and a pet in the household has no effect. Women report anxiety feelings more often than men. Older people report lower dissatisfaction and anxiety, remarkable given that the older population is among the most vulnerable in the current pandemic. Job-related changes due to COVID-19 such as income reduction and increase or decrease of workload are associated with more dissatisfaction and more anxiety. In reaction to the pandemic governments have adopted a range of measures. We show that restrictions on mobility and requirements to wear protective gear in public increase dissatisfaction and that the state-imposed emergency increase feelings of anxiety. We find that a growing number of confirmed COVID-19 cases increases dissatisfaction and anxiety but that this effect levels off with a higher number of cases. Our findings support targeted government policies to preserve economic security, and increase stability of employment.JRC.I.1-Monitoring, Indicators & Impact Evaluatio

    The semicircular flow of the data economy

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    This paper revisits the traditional ‘circular flow’ of the macroeconomy (Samuelson, 1948) and reworks it to capture the use of big data and artificial intelligence in the economy. The characterisation builds on the multifaceted role of data to conceptualise markets and differentiate them depending on whether data is an output, a means of payment, or an input in knowledge extraction processes. After this, the main differences between the circular flow economy and the data economy are described, identifying the new flows and agents and the circular flow assumptions that do not seem to be as relevant to the workings of the data economy. The result is a ‘semicircular’ flow diagram: unprocessed data flow from individuals, families, and firms to data holders. Only data processed in the form of digital services flows back to families and firms. The new model is used to explore the potential for market failures. Knowledge extraction to generate digital services occurs within a ‘black box’ that displays natural monopoly characteristics. Data holders operate simultaneously in the markets for data generation and knowledge extraction. They generate the amount of knowledge that maximises their profit. This creates data underutilisation and asymmetries between data holders and other agents in the economy such as anti-trust authorities, central banks, scientific communities, consumers, and firms. Public intervention should facilitate additional generation of knowledge by developing additional merit and non-rival uses of data in such a way that knowledge generation maximises the social gain from digitalisation. The semicircular model can incorporate data leakages and knowledge injections activated by data taxation. Data taxes should be paid with data respecting existing legislation, privacy concerns, and preserve the incentives of the data holder to innovate in competitive data generation markets. A centralised data authority, as initially proposed by Martens (2016) and more recently by Scott Morton et al. (2019), would be responsible for knowledge generation and aim to achieve better regulation, standards, and transparency, and maximise common good. Our conclusions are in line with an extensive user-centric approach to data portability (De Hert et al., 2018). This paper contributes to the digital economy discussion by developing a simple theoretical motivation for increased access to data for the public good, which will stimulate further theoretical and empirical exercises and lead to policy actions.JRC.I.1-Monitoring, Indicators & Impact Evaluatio

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

    Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

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    PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

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    PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

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    Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio

    Search for supersymmetry in events with one lepton and multiple jets in proton-proton collisions at root s=13 TeV

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